propionic acid
propionic acid is a lipid of Fatty Acyls (FA) class. Propionic acid is associated with abnormalities such as Epilepsy, Infection, Tuberculosis, Alkalosis and Ischemia. The involved functions are known as Uptake, Biosynthetic Pathways, Methylation, Protein Overexpression and Biochemical Pathway. Propionic acid often locates in Body tissue, Cytoplasmic matrix, Membrane, Protoplasm and Extracellular. The associated genes with propionic acid are TRIO gene, TRRAP gene, SLC5A8 gene, SLC33A1 gene and Homologous Gene. The related lipids are Fatty Acids, Propionate, butyrate, Valerates and mycocerosic acid.
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Introduction
To understand associated biological information of propionic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with propionic acid?
propionic acid is suspected in Propionic acidemia, Ischemia, Infection, Ulcerative Colitis, Alkalosis, Methylmalonic acidemia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with propionic acid
PubChem Associated disorders and diseases
What pathways are associated with propionic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with propionic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with propionic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with propionic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with propionic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with propionic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with propionic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wilkemeyer MF et al. | Primary structure and activity of mouse methylmalonyl-CoA mutase. | 1990 | Biochem. J. | pmid:1978672 |
| Timkovich R | Chemical modification of the haem propionate of cytochrome c. | 1980 | Biochem. J. | pmid:6246879 |
| Hashimoto S and Hayakawa S | Microbiological degradation of bile acids. Metabolites formed from 3-(3a alpha-hexahydro-7a beta-methyl-1,5-dioxoindan-4 alpha-yl) propionic acid by Streptomyces rubescens. | 1977 | Biochem. J. | pmid:883963 |
| Ghosh NK et al. | Induction of human choriogonadotropin in heLa-cell cultures by aliphatic monocarboxylates and inhibitors of deoxyribonucleic acid synthesis. | 1977 | Biochem. J. | pmid:911320 |
| Scholem RD and Brown GK | Metabolism of malonic semialdehyde in man. | 1983 | Biochem. J. | pmid:6418146 |
| Zaleski J and Bryła J | Effect of alloxan-diabetes on gluconeogenesis and ureogenesis in isolated rabbit liver cells. | 1978 | Biochem. J. | pmid:743258 |
| Mathews AJ and Brittain T | Chemical modification of the haem propionate of cytochrome c. A re-evaluation of the reaction of cytochrome c with a water-soluble carbodi-imide. | 1986 | Biochem. J. | pmid:3030276 |
| Seehra JS et al. | Anaerobic and aerobic coproporphyrinogen III oxidases of Rhodopseudomonas spheroides. Mechanism and stereochemistry of vinyl group formation. | 1983 | Biochem. J. | pmid:6603215 |
| Jia Y et al. | Kinetics and product analysis of the reaction catalysed by recombinant homoaconitase from Thermus thermophilus. | 2006 | Biochem. J. | pmid:16524361 |
| Shepherd M et al. | Purification and kinetic characterization of the magnesium protoporphyrin IX methyltransferase from Synechocystis PCC6803. | 2003 | Biochem. J. | pmid:12489983 |
| Lomax MA et al. | Differences between lactating and non-lactating dairy cows in concentration and secretion rate of insulin. | 1979 | Biochem. J. | pmid:486110 |
| Sherry AD et al. | Propionate metabolism in the rat heart by 13C n.m.r. spectroscopy. | 1988 | Biochem. J. | pmid:3178775 |
| Girvan HM et al. | Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3. | 2010 | Biochem. J. | pmid:20180779 |
| KENTEN RH | The oxidation of beta-(3-indolyl) propionic acid and gamma-(3-indolyl)-n-butyric acid by peroxidase and Mn2+. | 1955 | Biochem. J. | pmid:13269367 |
| Williams DL et al. | Metabolic effects of propionate administration to normal and vitamin B12-deficient rats. | 1971 | Biochem. J. | pmid:5116531 |
| Nyhan WL et al. | Tiglicaciduria in propionicacidaemia. | 1972 | Biochem. J. | pmid:5073234 |
| Chan TM and Freedland RA | The effect of propionate on the metabolism of pyruvate and lactate in the perfused rat liver. | 1972 | Biochem. J. | pmid:5076196 |
| Ryan JP and Ryan H | The role of intracellular pH in the regulation of cation exchanges in yeast. | 1972 | Biochem. J. | pmid:4563763 |
| Srinivas SR et al. | Cloning and functional identification of slc5a12 as a sodium-coupled low-affinity transporter for monocarboxylates (SMCT2). | 2005 | Biochem. J. | pmid:16104846 |
| Jones A and Turner JM | Microbial metabolism of amino alcohols. 1-Aminopropan-2-ol and ethanolamine metabolism via propionaldehyde and acetaldehyde in a species of Pseudomonas. | 1973 | Biochem. J. | pmid:4723219 |
| Narumi K et al. | Biosynthesis of a mycobacterial lipopolysaccharide. Incorporation of (14C)acyl groups by whole cells in vivo. | 1973 | Biochem. J. | pmid:4725042 |
| Brass EP et al. | Inhibition of oxidative metabolism by propionic acid and its reversal by carnitine in isolated rat hepatocytes. | 1986 | Biochem. J. | pmid:3790065 |
| Grunnet N and Katz J | Effects of ammonia and norvaline on lactate metabolism by hepatocytes from starved rats. The use of 14C-labelled lactate in studies of hepatic gluconeogenesis. | 1978 | Biochem. J. | pmid:687361 |
| Killilea SD et al. | Structures and apoprotein linkages of phycoerythrobilin and phycocyanobilin. | 1980 | Biochem. J. | pmid:7396852 |
| Pappu AS et al. | Possible interrelationship between vitamins E and b12 in the disturbance in methylmalonate metabolism in vitamin E deficiency. | 1978 | Biochem. J. | pmid:656065 |
| Burger-van Paassen N et al. | The regulation of intestinal mucin MUC2 expression by short-chain fatty acids: implications for epithelial protection. | 2009 | Biochem. J. | pmid:19228118 |
| Iwaki A and Izawa S | Acidic stress induces the formation of P-bodies, but not stress granules, with mild attenuation of bulk translation in Saccharomyces cerevisiae. | 2012 | Biochem. J. | pmid:22686455 |
| Sumegi B et al. | Metabolism of [3-13C]pyruvate and [3-13C]propionate in normal and ischaemic rat heart in vivo: 1H- and 13C-NMR studies. | 1995 | Biochem. J. | pmid:7492338 |
| Koshihara Y et al. | Effect of sodium n-butyrate on induction of prostaglandin synthase activity in cloned mastocytoma P-815 2-E-6 cells. | 1981 | Biochem. J. | pmid:6796055 |
| Arinze IJ et al. | Effect of methylamalonic acid on gluconeogenesis in isolated rat and guinea-pig hepatocytes. | 1979 | Biochem. J. | pmid:540062 |
| Giudici TA et al. | Methylmalonic and propionic acidemias: lipid profiles of normal and affected human skin fibroblasts incubated with [1-14C]propionate. | 1986 | Biochem. Med. Metab. Biol. | pmid:2872907 |
| Marsden D et al. | Anabolic effect of human growth hormone: management of inherited disorders of catabolic pathways. | 1994 | Biochem. Med. Metab. Biol. | pmid:7993663 |
| Michalik M and Bryła J | Inhibitory effect of gentamicin on gluconeogenesis from pyruvate, propionate, and lactate in isolated rabbit kidney-cortex tubules. | 1987 | Biochem. Med. Metab. Biol. | pmid:3663396 |
| Dutra JC et al. | Effects of methylmalonate and propionate on uptake of glucose and ketone bodies in vitro by brain of developing rats. | 1991 | Biochem. Med. Metab. Biol. | pmid:2015109 |
| de Mello CF et al. | Effects of methylmalonate and propionate on [3H]glutamate binding, adenylate cyclase activity and lipid synthesis in rat cerebral cortex. | 1997 | Biochem. Mol. Biol. Int. | pmid:9305532 |
| Larrey D et al. | Effects of erythromycin on hepatic drug-metabolizing enzymes in humans. | 1983 | Biochem. Pharmacol. | pmid:6838653 |
| Wang H et al. | Characterizing the effect of UDP-glucuronosyltransferase (UGT) 2B7 and UGT1A9 genetic polymorphisms on enantioselective glucuronidation of flurbiprofen. | 2011 | Biochem. Pharmacol. | pmid:21856293 |
| Larrey D et al. | Formation of inactive cytochrome P-450 Fe(II)-metabolite complexes with several erythromycin derivatives but not with josamycin and midecamycin in rats. | 1983 | Biochem. Pharmacol. | pmid:6860368 |
| Otagiri M et al. | Binding of pirprofen to human serum albumin studied by dialysis and spectroscopy techniques. | 1989 | Biochem. Pharmacol. | pmid:2910295 |
| Nambi P et al. | Induction of functional beta-adrenergic receptors in rat aortic smooth muscle cells by sodium butyrate. | 1986 | Biochem. Pharmacol. | pmid:3022740 |
| Krahenbuhl S and Brass EP | Inhibition of hepatic propionyl-CoA synthetase activity by organic acids. Reversal of propionate inhibition of pyruvate metabolism. | 1991 Mar 15-Apr 1 | Biochem. Pharmacol. | pmid:2009071 |
| Muramatsu M et al. | Enhancement of affinity to receptors in the esterified glucocorticoid, hydrocortisone 17-butyrate 21-propionate (HBP), in the rat liver. | 1986 | Biochem. Pharmacol. | pmid:3718538 |
| Sumegi B et al. | Is there tight channelling in the tricarboxylic acid cycle metabolon? | 1991 | Biochem. Soc. Trans. | pmid:1794455 |
| Rwere F et al. | Resonance Raman interrogation of the consequences of heme rotational disorder in myoglobin and its ligated derivatives. | 2008 | Biochemistry | pmid:18986170 |
| Liu GY et al. | Ionic strength dependence of cytochrome c structure and Trp-59 H/D exchange from ultraviolet resonance Raman spectroscopy. | 1989 | Biochemistry | pmid:2548599 |
| Dayem LC et al. | Metabolic engineering of a methylmalonyl-CoA mutase-epimerase pathway for complex polyketide biosynthesis in Escherichia coli. | 2002 | Biochemistry | pmid:11955068 |
| Horswill AR and Escalante-Semerena JC | Characterization of the propionyl-CoA synthetase (PrpE) enzyme of Salmonella enterica: residue Lys592 is required for propionyl-AMP synthesis. | 2002 | Biochemistry | pmid:11841231 |
| Stayton PS et al. | Putidaredoxin competitively inhibits cytochrome b5-cytochrome P-450cam association: a proposed molecular model for a cytochrome P-450cam electron-transfer complex. | 1989 | Biochemistry | pmid:2690937 |
| Evans HJ and Wood HG | Purification and properties of pyruvate phosphate dikinase from propionic acid bacteria. | 1971 | Biochemistry | pmid:5544662 |
| Ahmed AH et al. | Mechanisms of antagonism of the GluR2 AMPA receptor: structure and dynamics of the complex of two willardiine antagonists with the glutamate binding domain. | 2009 | Biochemistry | pmid:19284741 |