propionic acid

propionic acid is a lipid of Fatty Acyls (FA) class. Propionic acid is associated with abnormalities such as Epilepsy, Infection, Tuberculosis, Alkalosis and Ischemia. The involved functions are known as Uptake, Biosynthetic Pathways, Methylation, Protein Overexpression and Biochemical Pathway. Propionic acid often locates in Body tissue, Cytoplasmic matrix, Membrane, Protoplasm and Extracellular. The associated genes with propionic acid are TRIO gene, TRRAP gene, SLC5A8 gene, SLC33A1 gene and Homologous Gene. The related lipids are Fatty Acids, Propionate, butyrate, Valerates and mycocerosic acid.

Cross Reference

Introduction

To understand associated biological information of propionic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with propionic acid?

propionic acid is suspected in Propionic acidemia, Ischemia, Infection, Ulcerative Colitis, Alkalosis, Methylmalonic acidemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with propionic acid

MeSH term MeSH ID Detail
Hyperlipoproteinemia Type II D006938 22 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Ischemia D007511 18 associated lipids
Glycosuria D006029 10 associated lipids
Seizures D012640 87 associated lipids
Nerve Degeneration D009410 53 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Hypertension D006973 115 associated lipids
Periodontitis D010518 22 associated lipids
Testicular Neoplasms D013736 5 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Leukemia, Lymphocytic, Chronic, B-Cell D015451 25 associated lipids
Galactosemias D005693 5 associated lipids
Erythema D004890 22 associated lipids
Ventricular Fibrillation D014693 16 associated lipids
Hyperlipidemias D006949 73 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Cardiomegaly D006332 31 associated lipids
Burkitt Lymphoma D002051 15 associated lipids
Rickets D012279 6 associated lipids
Arthritis, Juvenile D001171 8 associated lipids
Malabsorption Syndromes D008286 16 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Uveitis D014605 14 associated lipids
Reye Syndrome D012202 14 associated lipids
Poultry Diseases D011201 21 associated lipids
Hyperinsulinism D006946 27 associated lipids
Farmer's Lung D005203 2 associated lipids
Stevens-Johnson Syndrome D013262 3 associated lipids
Blind Loop Syndrome D001765 3 associated lipids
Coccidiosis D003048 3 associated lipids
Salmonella Infections, Animal D012481 9 associated lipids
Dysmenorrhea D004412 9 associated lipids
Drug Eruptions D003875 30 associated lipids
Campylobacter Infections D002169 13 associated lipids
Genetic Predisposition to Disease D020022 24 associated lipids
Atherosclerosis D050197 85 associated lipids
Gram-Positive Bacterial Infections D016908 3 associated lipids
Sleep Apnea, Obstructive D020181 9 associated lipids
Hepatoblastoma D018197 10 associated lipids
Cecal Diseases D002429 3 associated lipids
Foot-and-Mouth Disease D005536 1 associated lipids
Puerperal Disorders D011644 4 associated lipids
Candidiasis, Oral D002180 11 associated lipids
Stomatitis D013280 14 associated lipids
Tinea D014005 5 associated lipids
Gingival Diseases D005882 1 associated lipids
Bursitis D002062 3 associated lipids
Tendinopathy D052256 3 associated lipids
Tooth, Impacted D014095 9 associated lipids
Per page 10 20 50 100 | Total 142

PubChem Associated disorders and diseases

What pathways are associated with propionic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with propionic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with propionic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with propionic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with propionic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with propionic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with propionic acid

Download all related citations
Per page 10 20 50 100 | Total 6372
Authors Title Published Journal PubMed Link
Murphy EJ et al. Engineering the substrate specificity and reactivity of a heme protein: creation of an ascorbate binding site in cytochrome c peroxidase. 2008 Biochemistry pmid:19061385
Busse SC and Jue T Two-dimensional NMR characterization of the deoxymyoglobin heme pocket. 1994 Biochemistry pmid:8086410
Sherry AD et al. Orientation-conserved transfer of symmetric Krebs cycle intermediates in mammalian tissue. 1994 Biochemistry pmid:7910760
LeMagueres P et al. Crystal structure at 1.45 A resolution of alanine racemase from a pathogenic bacterium, Pseudomonas aeruginosa, contains both internal and external aldimine forms. 2003 Biochemistry pmid:14674749
de Vitry C et al. Biochemical and spectroscopic characterization of the covalent binding of heme to cytochrome b6. 2004 Biochemistry pmid:15049703
Ibrahim M et al. Soluble guanylate cyclase is activated differently by excess NO and by YC-1: resonance Raman spectroscopic evidence. 2010 Biochemistry pmid:20459051
Rwere F et al. Resonance Raman interrogation of the consequences of heme rotational disorder in myoglobin and its ligated derivatives. 2008 Biochemistry pmid:18986170
Ren Y et al. Mapping the electron transfer interface between cytochrome b5 and cytochrome c. 2004 Biochemistry pmid:15035623
Louie GV et al. Role of phenylalanine-82 in yeast iso-1-cytochrome c and remote conformational changes induced by a serine residue at this position. 1988 Biochemistry pmid:2849996
Manna SK and Mazumdar S Role of threonine 101 on the stability of the heme active site of cytochrome P450cam: multiwavelength circular dichroism studies. 2006 Biochemistry pmid:17042489
Seibold SA et al. Water chain formation and possible proton pumping routes in Rhodobacter sphaeroides cytochrome c oxidase: a molecular dynamics comparison of the wild type and R481K mutant. 2005 Biochemistry pmid:16060656
Haller T et al. Discovering new enzymes and metabolic pathways: conversion of succinate to propionate by Escherichia coli. 2000 Biochemistry pmid:10769117
Timkovich R et al. 1H NMR spectroscopy of Paracoccus denitrificans cytochrome c-550. 1984 Biochemistry pmid:6087896
Yang X et al. Cholesterol metabolism increases the metabolic pool of propionate in Mycobacterium tuberculosis. 2009 Biochemistry pmid:19364125
Santucci R et al. Anion size modulates the structure of the A state of cytochrome c. 2000 Biochemistry pmid:11027143
Yoshimura H et al. Specific hydrogen-bonding networks responsible for selective O2 sensing of the oxygen sensor protein HemAT from Bacillus subtilis. 2006 Biochemistry pmid:16819829
Hellwig P et al. Electrochemical, FTIR, and UV/VIS spectroscopic properties of the ba(3) oxidase from Thermus thermophilus. 1999 Biochemistry pmid:10423243
Sakurai M et al. Glutamate 325 is a general acid-base catalyst in the reaction catalyzed by fructose-2,6-bisphosphatase. 2000 Biochemistry pmid:11123954
Mikami S et al. Effect of the redox-dependent ionization state of the heme propionic acid side chain on the entropic contribution to the redox potential of Pseudomonas aeruginosa cytochrome c551. 2009 Biochemistry pmid:19627115
Mauk MR et al. Electrostatic analysis of the interaction of cytochrome c with native and dimethyl ester heme substituted cytochrome b5. 1986 Biochemistry pmid:3026446
Chao YY et al. 1H NMR and ESR studies of oxidized cytochrome c551 from Pseudomonas aeruginosa. 1979 Biochemistry pmid:33701
Peng D et al. Role of propionates in substrate binding to heme oxygenase from Neisseria meningitidis: a nuclear magnetic resonance study. 2012 Biochemistry pmid:22913621
Chen Z et al. Resonance Raman investigation of the interaction of thromboxane synthase with substrate analogues. 2003 Biochemistry pmid:12614148
Peyton DH et al. Proton nuclear magnetic resonance study of the molecular and electronic structure of the heme cavity in Aplysia cyanometmyoglobin. 1989 Biochemistry pmid:2548594
Liu GY et al. Ionic strength dependence of cytochrome c structure and Trp-59 H/D exchange from ultraviolet resonance Raman spectroscopy. 1989 Biochemistry pmid:2548599
Omura S et al. Studies on the biosynthesis of 16-membered macrolide antibiotics using carbon-13 nuclear magnetic resonance spectroscopy. 1977 Biochemistry pmid:18162
Wilson DF and Forman NG Mitochondrial transmembrane pH and electrical gradients: evaluation of their energy relationships with respiratory rate and adenosine 5'-triphosphate synthesis. 1982 Biochemistry pmid:7074098
Wang J et al. Alteration of the regiospecificity of human heme oxygenase-1 by unseating of the heme but not disruption of the distal hydrogen bonding network. 2006 Biochemistry pmid:16388581
Stellwagen E and Babul J Stabilization of the globular structure of ferricytochrome c by chloride in acidic solvents. 1975 Biochemistry pmid:41
Mascaretti OA et al. Biosynthesis of the macrolide antibiotic chlorothricin. 1981 Biochemistry pmid:7011379
Mimura K et al. Isolation of stable (alphabeta)4-Tetraprotomer from Na+/K+-ATPase solubilized in the presence of short-chain fatty acids. 2008 Biochemistry pmid:18465843
Baddam S and Bowler BE Thermodynamics and kinetics of formation of the alkaline state of a Lys 79-->Ala/Lys 73-->His variant of iso-1-cytochrome c. 2005 Biochemistry pmid:16274242
Lee HJ et al. Properties of Arg481 mutants of the aa3-type cytochrome c oxidase from Rhodobacter sphaeroides suggest that neither R481 nor the nearby D-propionate of heme a3 is likely to be the proton loading site of the proton pump. 2009 Biochemistry pmid:19575527
Dayem LC et al. Metabolic engineering of a methylmalonyl-CoA mutase-epimerase pathway for complex polyketide biosynthesis in Escherichia coli. 2002 Biochemistry pmid:11955068
Brigé A et al. The 1.25 A resolution structure of the diheme NapB subunit of soluble nitrate reductase reveals a novel cytochrome c fold with a stacked heme arrangement. 2002 Biochemistry pmid:11939777
Behr J et al. Functional properties of the heme propionates in cytochrome c oxidase from Paracoccus denitrificans. Evidence from FTIR difference spectroscopy and site-directed mutagenesis. 2000 Biochemistry pmid:10684616
Horswill AR and Escalante-Semerena JC Characterization of the propionyl-CoA synthetase (PrpE) enzyme of Salmonella enterica: residue Lys592 is required for propionyl-AMP synthesis. 2002 Biochemistry pmid:11841231
Delker SL et al. Role of zinc in isoform-selective inhibitor binding to neuronal nitric oxide synthase . 2010 Biochemistry pmid:21138269
Bunik VI et al. Phosphonate analogues of alpha-ketoglutarate inhibit the activity of the alpha-ketoglutarate dehydrogenase complex isolated from brain and in cultured cells. 2005 Biochemistry pmid:16060664
Brändén G et al. The protonation state of a heme propionate controls electron transfer in cytochrome c oxidase. 2005 Biochemistry pmid:16060655
Mills DA et al. An arginine to lysine mutation in the vicinity of the heme propionates affects the redox potentials of the hemes and associated electron and proton transfer in cytochrome c oxidase. 2005 Biochemistry pmid:16060654
Raman CS et al. Crystal structure of nitric oxide synthase bound to nitro indazole reveals a novel inactivation mechanism. 2001 Biochemistry pmid:11695891
Stayton PS et al. Putidaredoxin competitively inhibits cytochrome b5-cytochrome P-450cam association: a proposed molecular model for a cytochrome P-450cam electron-transfer complex. 1989 Biochemistry pmid:2690937
Sundaramoorthy M et al. High-resolution crystal structure of manganese peroxidase: substrate and inhibitor complexes. 2005 Biochemistry pmid:15850380
Andrews H et al. Expression, mutagenesis, and characterization of recombinant low-potential cytochrome c550 of photosystem II. 2005 Biochemistry pmid:15835898
Evans HJ and Wood HG Purification and properties of pyruvate phosphate dikinase from propionic acid bacteria. 1971 Biochemistry pmid:5544662
Ahmed AH et al. Mechanisms of antagonism of the GluR2 AMPA receptor: structure and dynamics of the complex of two willardiine antagonists with the glutamate binding domain. 2009 Biochemistry pmid:19284741
Schrimsher JL and Taylor KB Octopine dehydrogenase from Pecten maximus: steady-state mechanism. 1984 Biochemistry pmid:6722094
Mendoza MF et al. Human NAD(P)H:quinone oxidoreductase type I (hNQO1) activation of quinone propionic acid trigger groups. 2012 Biochemistry pmid:22989153
Shang L et al. Biliverdin amides reveal roles for propionate side chains in bilin reductase recognition and in holophytochrome assembly and photoconversion. 2010 Biochemistry pmid:20565135