propionic acid is a lipid of Fatty Acyls (FA) class. Propionic acid is associated with abnormalities such as Epilepsy, Infection, Tuberculosis, Alkalosis and Ischemia. The involved functions are known as Uptake, Biosynthetic Pathways, Methylation, Protein Overexpression and Biochemical Pathway. Propionic acid often locates in Body tissue, Cytoplasmic matrix, Membrane, Protoplasm and Extracellular. The associated genes with propionic acid are TRIO gene, TRRAP gene, SLC5A8 gene, SLC33A1 gene and Homologous Gene. The related lipids are Fatty Acids, Propionate, butyrate, Valerates and mycocerosic acid.
To understand associated biological information of propionic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
propionic acid is suspected in Propionic acidemia, Ischemia, Infection, Ulcerative Colitis, Alkalosis, Methylmalonic acidemia and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with propionic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Di Lisa F et al. | Contrasting effects of propionate and propionyl-L-carnitine on energy-linked processes in ischemic hearts. | 1994 | Am. J. Physiol. | pmid:8067396 |
Harada E and Kato S | Effect of short-chain fatty acids on the secretory response of the ovine exocrine pancreas. | 1983 | Am. J. Physiol. | pmid:6187225 |
Leffler CW et al. | cAMP production by piglet cerebral vascular smooth muscle cells: pH(o), pH(i), and permissive action of PGI(2). | 1999 | Am. J. Physiol. | pmid:10564143 |
Della-Fera MA et al. | Central nervous system injection of dynorphin-(1-13) overrides gastric satiety factors in sheep. | 1990 | Am. J. Physiol. | pmid:1970458 |
Grinstein S et al. | Amiloride-sensitive Na+-H+ exchange in platelets and leukocytes: detection by electronic cell sizing. | 1984 | Am. J. Physiol. | pmid:6089580 |
Nutting CW et al. | Vasorelaxant effects of short chain fatty acid salts in rat caudal artery. | 1991 | Am. J. Physiol. | pmid:1877681 |
Petersen KU and Reuss L | Electrophysiological effects of propionate and bicarbonate on gallbladder epithelium. | 1985 | Am. J. Physiol. | pmid:2981476 |
Harada E et al. | Potentiation of carbachol-induced amylase release by propionate in guinea pig and vole pancreatic acini. | 1999 | Am. J. Physiol. | pmid:10484494 |
Rabinowitz L et al. | Effects of glucagon, insulin, propionate, acetate, and HCO3 on K excretion in sheep. | 1984 | Am. J. Physiol. | pmid:6320683 |
Leclerc J et al. | Metabolism of R-beta-hydroxypentanoate and of beta-ketopentanoate in conscious dogs. | 1995 | Am. J. Physiol. | pmid:7900792 |
Wall SM and Koger LM | NH+4 transport mediated by Na(+)-K(+)-ATPase in rat inner medullary collecting duct. | 1994 | Am. J. Physiol. | pmid:7943362 |
Rowe WA et al. | Propionate activates multiple ion transport mechanisms in the HT29-18-C1 human colon cell line. | 1993 | Am. J. Physiol. | pmid:8214077 |
Graber M et al. | Acetazolamide inhibits acidification by the turtle bladder independent of cell pH. | 1989 | Am. J. Physiol. | pmid:2541630 |
Montrose MH et al. | Separate control of regulatory volume increase and Na+-H+ exchange by cultured renal cells. | 1988 | Am. J. Physiol. | pmid:2839037 |
Pi-Sunyer FX et al. | Glucagon, insulin, and gluconeogenesis in fasted odd carbon fatty acid-enriched rats. | 1976 | Am. J. Physiol. | pmid:961887 |
Ritucci NA et al. | Intracellular pH regulation in neurons from chemosensitive and nonchemosensitive areas of the medulla. | 1998 | Am. J. Physiol. | pmid:9756546 |
Keifer DW | Effect of weak acids on pH regulation and anion transport in barnacle muscle fibers. | 1981 | Am. J. Physiol. | pmid:7304732 |
Grinstein S and Furuya W | Characterization of the amiloride-sensitive Na+-H+ antiport of human neutrophils. | 1986 | Am. J. Physiol. | pmid:3953781 |
Forte JG et al. | Substrate dependency for HCl secretion by isolated piglet gastric mucosa. | 1980 | Am. J. Physiol. | pmid:7377308 |
Hsu P et al. | Mechanisms of hypercapnia-stimulated PG production in piglet cerebral microvascular endothelial cells. | 1995 | Am. J. Physiol. | pmid:7864184 |