propionic acid

propionic acid is a lipid of Fatty Acyls (FA) class. Propionic acid is associated with abnormalities such as Epilepsy, Infection, Tuberculosis, Alkalosis and Ischemia. The involved functions are known as Uptake, Biosynthetic Pathways, Methylation, Protein Overexpression and Biochemical Pathway. Propionic acid often locates in Body tissue, Cytoplasmic matrix, Membrane, Protoplasm and Extracellular. The associated genes with propionic acid are TRIO gene, TRRAP gene, SLC5A8 gene, SLC33A1 gene and Homologous Gene. The related lipids are Fatty Acids, Propionate, butyrate, Valerates and mycocerosic acid.

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Introduction

To understand associated biological information of propionic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with propionic acid?

propionic acid is suspected in Propionic acidemia, Ischemia, Infection, Ulcerative Colitis, Alkalosis, Methylmalonic acidemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with propionic acid

MeSH term MeSH ID Detail
Puerperal Disorders D011644 4 associated lipids
Ergotism D004881 4 associated lipids
Eczema D004485 4 associated lipids
Hyperammonemia D022124 5 associated lipids
Vasculitis, Leukocytoclastic, Cutaneous D018366 5 associated lipids
Testicular Neoplasms D013736 5 associated lipids
Growth Disorders D006130 5 associated lipids
Galactosemias D005693 5 associated lipids
Tinea D014005 5 associated lipids
Angioedema D000799 6 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with propionic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with propionic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with propionic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with propionic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with propionic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with propionic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with propionic acid

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Authors Title Published Journal PubMed Link
Della-Fera MA et al. Central nervous system injection of dynorphin-(1-13) overrides gastric satiety factors in sheep. 1990 Am. J. Physiol. pmid:1970458
de Hemptinne A et al. Influence of organic acids on intracellular pH. 1983 Am. J. Physiol. pmid:6614155
Conn AR et al. Characterization of alpha-keto acid transport across blood-brain barrier in rats. 1983 Am. J. Physiol. pmid:6614164
Graber M et al. Acetazolamide inhibits acidification by the turtle bladder independent of cell pH. 1989 Am. J. Physiol. pmid:2541630
Parfenova H and Leffler CW Effects of hypercapnia on prostanoid and cAMP production by cerebral microvascular cell cultures. 1996 Am. J. Physiol. pmid:8967453
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Mariadason JM et al. Effect of short-chain fatty acids on paracellular permeability in Caco-2 intestinal epithelium model. 1997 Am. J. Physiol. pmid:9142899
Yamaji Y et al. Intracellular acidosis activates c-Src. 1997 Am. J. Physiol. pmid:9124524
Rojas-García PP et al. Prenatal testosterone excess alters Sertoli and germ cell number and testicular FSH receptor expression in rams. 2010 Am. J. Physiol. Endocrinol. Metab. pmid:20858754
Cohen DM et al. Glutamine cycling in isolated working rat heart. 2003 Am. J. Physiol. Endocrinol. Metab. pmid:12944323
Martini WZ et al. Quantitative assessment of anaplerosis from propionate in pig heart in vivo. 2003 Am. J. Physiol. Endocrinol. Metab. pmid:12388135
Jones JG et al. An integrated (2)H and (13)C NMR study of gluconeogenesis and TCA cycle flux in humans. 2001 Am. J. Physiol. Endocrinol. Metab. pmid:11551863
King AJ et al. Hypertension caused by prenatal testosterone excess in female sheep. 2007 Am. J. Physiol. Endocrinol. Metab. pmid:17327368
Jin ES et al. Evidence for reverse flux through pyruvate kinase in skeletal muscle. 2009 Am. J. Physiol. Endocrinol. Metab. pmid:19190256
Wilson KA et al. Inter-relations between 3-hydroxypropionate and propionate metabolism in rat liver: relevance to disorders of propionyl-CoA metabolism. 2017 Am. J. Physiol. Endocrinol. Metab. pmid:28634175
Aschenbach JR et al. Bicarbonate-dependent and bicarbonate-independent mechanisms contribute to nondiffusive uptake of acetate in the ruminal epithelium of sheep. 2009 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:19264953
Tyagi S et al. Mechanism of n-butyrate uptake in the human proximal colonic basolateral membranes. 2002 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:11897627
Cremin JD et al. Glucose alleviates ammonia-induced inhibition of short-chain fatty acid metabolism in rat colonic epithelial cells. 2003 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:12637251
Hadjiagapiou C et al. Mechanism(s) of butyrate transport in Caco-2 cells: role of monocarboxylate transporter 1. 2000 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:11005765
Grider JR and Piland BE The peristaltic reflex induced by short-chain fatty acids is mediated by sequential release of 5-HT and neuronal CGRP but not BDNF. 2007 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:16973914