| MeSH term | MeSH ID | Detail |
|---|---|---|
| Angioedema | D000799 | 6 associated lipids |
| Rickets | D012279 | 6 associated lipids |
| Vaginitis | D014627 | 6 associated lipids |
| Liver Abscess | D008100 | 6 associated lipids |
| Dysentery, Bacillary | D004405 | 6 associated lipids |
| Phenylketonurias | D010661 | 7 associated lipids |
| Corynebacterium Infections | D003354 | 7 associated lipids |
| Hemoglobinopathies | D006453 | 7 associated lipids |
| Enterocolitis, Pseudomembranous | D004761 | 8 associated lipids |
| Arthritis, Juvenile | D001171 | 8 associated lipids |
propionic acid
propionic acid is a lipid of Fatty Acyls (FA) class. Propionic acid is associated with abnormalities such as Epilepsy, Infection, Tuberculosis, Alkalosis and Ischemia. The involved functions are known as Uptake, Biosynthetic Pathways, Methylation, Protein Overexpression and Biochemical Pathway. Propionic acid often locates in Body tissue, Cytoplasmic matrix, Membrane, Protoplasm and Extracellular. The associated genes with propionic acid are TRIO gene, TRRAP gene, SLC5A8 gene, SLC33A1 gene and Homologous Gene. The related lipids are Fatty Acids, Propionate, butyrate, Valerates and mycocerosic acid.
Cross Reference
Introduction
To understand associated biological information of propionic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with propionic acid?
propionic acid is suspected in Propionic acidemia, Ischemia, Infection, Ulcerative Colitis, Alkalosis, Methylmalonic acidemia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with propionic acid
PubChem Associated disorders and diseases
What pathways are associated with propionic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with propionic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with propionic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with propionic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with propionic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with propionic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with propionic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Busse SC and Jue T | Two-dimensional NMR characterization of the deoxymyoglobin heme pocket. | 1994 | Biochemistry | pmid:8086410 |
| Sherry AD et al. | Orientation-conserved transfer of symmetric Krebs cycle intermediates in mammalian tissue. | 1994 | Biochemistry | pmid:7910760 |
| LeMagueres P et al. | Crystal structure at 1.45 A resolution of alanine racemase from a pathogenic bacterium, Pseudomonas aeruginosa, contains both internal and external aldimine forms. | 2003 | Biochemistry | pmid:14674749 |
| Rwere F et al. | Resonance Raman interrogation of the consequences of heme rotational disorder in myoglobin and its ligated derivatives. | 2008 | Biochemistry | pmid:18986170 |
| Louie GV et al. | Role of phenylalanine-82 in yeast iso-1-cytochrome c and remote conformational changes induced by a serine residue at this position. | 1988 | Biochemistry | pmid:2849996 |
| Haller T et al. | Discovering new enzymes and metabolic pathways: conversion of succinate to propionate by Escherichia coli. | 2000 | Biochemistry | pmid:10769117 |
| Tran R et al. | Determinants of the heme-CO vibrational modes in the H-NOX family. | 2011 | Biochemistry | pmid:21714509 |
| Nagai M et al. | Heme structure of hemoglobin M Iwate [alpha 87(F8)His-->Tyr]: a UV and visible resonance Raman study. | 2000 | Biochemistry | pmid:11052661 |
| Yang X et al. | Cholesterol metabolism increases the metabolic pool of propionate in Mycobacterium tuberculosis. | 2009 | Biochemistry | pmid:19364125 |
| Santucci R et al. | Anion size modulates the structure of the A state of cytochrome c. | 2000 | Biochemistry | pmid:11027143 |
| Yoshimura H et al. | Specific hydrogen-bonding networks responsible for selective O2 sensing of the oxygen sensor protein HemAT from Bacillus subtilis. | 2006 | Biochemistry | pmid:16819829 |
| Mikami S et al. | Effect of the redox-dependent ionization state of the heme propionic acid side chain on the entropic contribution to the redox potential of Pseudomonas aeruginosa cytochrome c551. | 2009 | Biochemistry | pmid:19627115 |
| Peng D et al. | Role of propionates in substrate binding to heme oxygenase from Neisseria meningitidis: a nuclear magnetic resonance study. | 2012 | Biochemistry | pmid:22913621 |
| Cutler RL et al. | Role of arginine-38 in regulation of the cytochrome c oxidation-reduction equilibrium. | 1989 | Biochemistry | pmid:2545252 |
| Chen Z et al. | Resonance Raman investigation of the interaction of thromboxane synthase with substrate analogues. | 2003 | Biochemistry | pmid:12614148 |
| Peyton DH et al. | Proton nuclear magnetic resonance study of the molecular and electronic structure of the heme cavity in Aplysia cyanometmyoglobin. | 1989 | Biochemistry | pmid:2548594 |
| Liu GY et al. | Ionic strength dependence of cytochrome c structure and Trp-59 H/D exchange from ultraviolet resonance Raman spectroscopy. | 1989 | Biochemistry | pmid:2548599 |
| Omura S et al. | Studies on the biosynthesis of 16-membered macrolide antibiotics using carbon-13 nuclear magnetic resonance spectroscopy. | 1977 | Biochemistry | pmid:18162 |
| Mascaretti OA et al. | Biosynthesis of the macrolide antibiotic chlorothricin. | 1981 | Biochemistry | pmid:7011379 |
| Lee HJ et al. | Properties of Arg481 mutants of the aa3-type cytochrome c oxidase from Rhodobacter sphaeroides suggest that neither R481 nor the nearby D-propionate of heme a3 is likely to be the proton loading site of the proton pump. | 2009 | Biochemistry | pmid:19575527 |
| Dayem LC et al. | Metabolic engineering of a methylmalonyl-CoA mutase-epimerase pathway for complex polyketide biosynthesis in Escherichia coli. | 2002 | Biochemistry | pmid:11955068 |
| Brigé A et al. | The 1.25 A resolution structure of the diheme NapB subunit of soluble nitrate reductase reveals a novel cytochrome c fold with a stacked heme arrangement. | 2002 | Biochemistry | pmid:11939777 |
| Behr J et al. | Functional properties of the heme propionates in cytochrome c oxidase from Paracoccus denitrificans. Evidence from FTIR difference spectroscopy and site-directed mutagenesis. | 2000 | Biochemistry | pmid:10684616 |
| Horswill AR and Escalante-Semerena JC | Characterization of the propionyl-CoA synthetase (PrpE) enzyme of Salmonella enterica: residue Lys592 is required for propionyl-AMP synthesis. | 2002 | Biochemistry | pmid:11841231 |
| Raman CS et al. | Crystal structure of nitric oxide synthase bound to nitro indazole reveals a novel inactivation mechanism. | 2001 | Biochemistry | pmid:11695891 |
| Stayton PS et al. | Putidaredoxin competitively inhibits cytochrome b5-cytochrome P-450cam association: a proposed molecular model for a cytochrome P-450cam electron-transfer complex. | 1989 | Biochemistry | pmid:2690937 |
| Ahmed AH et al. | Mechanisms of antagonism of the GluR2 AMPA receptor: structure and dynamics of the complex of two willardiine antagonists with the glutamate binding domain. | 2009 | Biochemistry | pmid:19284741 |
| Sherman MM and Hutchinson CR | Biosynthesis of lasalocid A: biochemical mechanism for assembly of the carbon framework. | 1987 | Biochemistry | pmid:3828316 |
| Shang L et al. | Biliverdin amides reveal roles for propionate side chains in bilin reductase recognition and in holophytochrome assembly and photoconversion. | 2010 | Biochemistry | pmid:20565135 |
| Sivuk VF et al. | Purification and characteristics of functional properties of soluble nucleoside triphosphatase (apyrase) from bovine brain. | 2008 | Biochemistry Mosc. | pmid:18976223 |
| Kondakova AN et al. | New structures of the O-specific polysaccharides of Proteus. 3. Polysaccharides containing non-carbohydrate organic acids. | 2003 | Biochemistry Mosc. | pmid:12765528 |
| Morishima I and Iizuka T | Nuclear magnetic resonance studies of hemoproteins. IV. Hindered rotation of heme side methyl group as a probe for studying van der Waals contacts in the heme side environments of myoglobin derivatives. | 1975 | Biochim. Biophys. Acta | pmid:1169971 |
| Enser U and Heber U | Metabolic regulation by pH gradients. Inhibition of photosynthesis by indirect proton transfer across the chloroplast envelope. | 1980 | Biochim. Biophys. Acta | pmid:6251871 |
| Yount EA and Harris RA | Studies on the inhibition of gluconeogenesis by oxalate. | 1980 | Biochim. Biophys. Acta | pmid:6778509 |
| Koutsoupakis C et al. | Time-resolved step-scan Fourier transform infrared investigation of heme-copper oxidases: implications for O2 input and H2O/H+ output channels. | 2004 | Biochim. Biophys. Acta | pmid:15100050 |
| Sorenson MM and De Meis L | Effects of anions, pH and magnesium on calcium accumulation and release by sarcoplasmic reticulum vesicles. | 1977 | Biochim. Biophys. Acta | pmid:16250336 |
| Taylor A et al. | The effects of propionate on sodium transport by the toad bladder. Evidence for a metabolic mode of action. | 1973 | Biochim. Biophys. Acta | pmid:4198138 |
| Riistama S et al. | Interaction between the formyl group of heme a and arginine 54 in cytochrome aa(3) from Paracoccus denitrificans. | 2000 | Biochim. Biophys. Acta | pmid:10611451 |
| Roos P et al. | Isolation of five active thyrotropin components from human pituitary gland. | 1975 | Biochim. Biophys. Acta | pmid:1125234 |
| Tomaro ML et al. | The oxidation of hemins by microsomal heme oxygenase. Structural requirements for the retention of substrate activity. | 1984 | Biochim. Biophys. Acta | pmid:6549143 |
| Wirthensohn G and Guder WG | Phosphatidylcholine biosynthesis in rabbit kidney tubule suspensions. Effect of metabolic substrates on precursor incorporation. | 1983 | Biochim. Biophys. Acta | pmid:6860690 |
| Alonso WR and Nelson DA | A novel yeast histone deacetylase: partial characterization and development of an activity assay. | 1986 | Biochim. Biophys. Acta | pmid:3513841 |
| Ku EC and Wasvary JM | Inhibition of prostaglandin synthase by pirprofen. Studies with sheep seminal vesicle enzyme. | 1975 | Biochim. Biophys. Acta | pmid:804924 |
| Moore GR et al. | A spectroscopic investigation of the structure and redox properties of Escherichia coli cytochrome b-562. | 1985 | Biochim. Biophys. Acta | pmid:2986699 |
| Martin JF and Mcdaniel LE | Specific inhibition of candicidin biosynthesis by the lipogenic inhibitor cerulenin. | 1975 | Biochim. Biophys. Acta | pmid:811262 |
| Yamamoto Y et al. | 1H-NMR study of dynamics and thermodynamics of Cl- binding to ferric hemoglobin of a midge larva (Tokunagayusurika akamusi). | 2003 | Biochim. Biophys. Acta | pmid:14644049 |
| Fonteriz RI et al. | The role of intracellular acidification in calcium mobilization in human neutrophils. | 1991 | Biochim. Biophys. Acta | pmid:2049405 |
| Moore GR et al. | pH dependence of the redox potential of Pseudomonas aeruginosa cytochrome c-551. | 1980 | Biochim. Biophys. Acta | pmid:6245686 |
| Wall MJ et al. | The effect of short chain fatty acids on transmural electrical potential across rat small intestine in vivo. | 1976 | Biochim. Biophys. Acta | pmid:179592 |
| Yoshikawa S et al. | Proton pumping mechanism of bovine heart cytochrome c oxidase. | Biochim. Biophys. Acta | pmid:16904626 | |
| Keller RM and Wüthrich K | Assignment of the heme c resonances in the 360 MHz H NMR spectra of cytochrome c. | 1978 | Biochim. Biophys. Acta | pmid:205265 |
| Loureiro SO et al. | Propionic and methylmalonic acids increase cAMP levels in slices of cerebral cortex of young rats via adrenergic and glutamatergic mechanisms. | 2005 | Biochim. Biophys. Acta | pmid:15949715 |
| Dyer C et al. | Cyanide reactivity of cytochrome c derivatives. | 1979 | Biochim. Biophys. Acta | pmid:231457 |
| Yu MA et al. | Radical formation in cytochrome c oxidase. | 2011 | Biochim. Biophys. Acta | pmid:21718686 |
| Hess JJ et al. | On the effects of propionate and other short-chain fatty acids on sodium transport by the toad bladder. | 1975 | Biochim. Biophys. Acta | pmid:236789 |
| Henly DC and Berry MN | Relationship between the stimulation of citric acid cycle oxidation and the stimulation of fatty acid esterification and inhibition of ketogenesis by lactate in isolated rat hepatocytes. | 1991 | Biochim. Biophys. Acta | pmid:1828700 |
| Grinstein S et al. | Chemical modification of the Na+/H+ exchanger of thymic lymphocytes. Inhibition by N-ethylmaleimide. | 1985 | Biochim. Biophys. Acta | pmid:2981544 |
| de Silva DG and Sykes AG | Interpretation of effects of pH on rate constants for the oxidation of three ferrocytochromes c-551 with [Fe(CN)6]3- and [Co(phen)3]3+, and assignment of pKa values. | 1988 | Biochim. Biophys. Acta | pmid:2827782 |
| Lancaster CR et al. | Recent progress on obtaining theoretical and experimental support for the "E-pathway hypothesis" of coupled transmembrane electron and proton transfer in dihaem-containing quinol:fumarate reductase. | 2006 | Biochim. Biophys. Acta | pmid:16790236 |
| Knight LC and Welch MJ | Sites of direct and indirect halogenation of albumin. | 1978 | Biochim. Biophys. Acta | pmid:27226 |
| Wikström M et al. | Water-gated mechanism of proton translocation by cytochrome c oxidase. | 2003 | Biochim. Biophys. Acta | pmid:12765763 |
| Pettigrew GW et al. | Redox potentials of the photosynthetic bacterial cytochromes c2 and the structural bases for variability. | 1978 | Biochim. Biophys. Acta | pmid:28760 |
| Wasternack C et al. | Pyrimidine-degrading enzymes. Purification and properties of beta-ureidopropionase of Euglena gracilis. | 1979 | Biochim. Biophys. Acta | pmid:115499 |
| Trewhella J and Wright PE | 1H-NMR studies of ferric soybean leghemoglobin: assignment of hyperfine shifted resonances of complexes with cyanide, nicotinate, pyridine and azide. | 1980 | Biochim. Biophys. Acta | pmid:7192162 |
| Keller R et al. | Contact-shifted resonances in the 1H NMR spectra of cytochrome b5. Resonance identification and spin density distribution in the heme group. | 1976 | Biochim. Biophys. Acta | pmid:5127 |
| Baskin LS and Yang CS | Cross-linking studies of the protein topography of rat liver microsomes. | 1982 | Biochim. Biophys. Acta | pmid:7055568 |
| Rafidinarivo E et al. | Branched fatty acids from Mycobacterium aurum. | 1982 | Biochim. Biophys. Acta | pmid:7093295 |
| Rotsaert FA et al. | Mutations in cytochrome b that affect kinetics of the electron transfer reactions at center N in the yeast cytochrome bc1 complex. | 2008 | Biochim. Biophys. Acta | pmid:18328328 |
| Adir N et al. | Refined structure of c-phycocyanin from the cyanobacterium Synechococcus vulcanus at 1.6 A: insights into the role of solvent molecules in thermal stability and co-factor structure. | 2002 | Biochim. Biophys. Acta | pmid:12460674 |
| HASSALL H and GREENBERG DM | The oxidation of 4(5)-imidazolone-5(4)-propionic acid to hydantoin-5-propionic acid by xanthine oxidase. | 1963 | Biochim. Biophys. Acta | pmid:13960896 |
| Peuhkurinen KJ | Accumulation and disposal of tricarboxylic acid cycle intermediates during propionate oxidation in the isolated perfused rat heart. | 1982 | Biochim. Biophys. Acta | pmid:7138913 |
| Fiedor L et al. | Understanding chlorophylls: central magnesium ion and phytyl as structural determinants. | 2008 | Biochim. Biophys. Acta | pmid:18848915 |
| Fafournoux P et al. | Propionate transport in rat liver cells. | 1985 | Biochim. Biophys. Acta | pmid:4016114 |
| Bear CE et al. | Intracellular pH influences the resting membrane potential of isolated rat hepatocytes. | 1988 | Biochim. Biophys. Acta | pmid:3179283 |
| Ticku MK and Olsen RW | gamma-Aminobutyric acid-stimulated chloride permeability in crayfish muscle. | 1977 | Biochim. Biophys. Acta | pmid:836825 |
| Ziyadeh FN et al. | Taurine and cell volume maintenance in the shark rectal gland: cellular fluxes and kinetics. | 1988 | Biochim. Biophys. Acta | pmid:2840958 |
| Xu J and Voth GA | Redox-coupled proton pumping in cytochrome c oxidase: further insights from computer simulation. | 2008 | Biochim. Biophys. Acta | pmid:18155154 |
| TOMLINSON N and MACLEOD RA | The oxidation of propionic acid by a marine bacterium. | 1955 | Biochim. Biophys. Acta | pmid:13304045 |
| Dwyer LA et al. | A 13C-NMR study of the biosynthesis of 3-methylpentacosane in the American cockroach. | 1981 | Biochim. Biophys. Acta | pmid:6894252 |
| Itoh N et al. | Cloning and biochemical characterization of Co(2+)-activated bromoperoxidase-esterase (perhydrolase) from Pseudomonas putida IF-3 strain. | 2001 | Biochim. Biophys. Acta | pmid:11342031 |
| WOOD HG and LEAVER FW | CO2 turnover in the fermentation of 3,4,5 and 6 carbon compounds by the propionic acid bacteria. | Biochim. Biophys. Acta | pmid:13115430 | |
| Kay WW | Genetic control of the metabolism of propionate by Escherichia coli K12. | 1972 | Biochim. Biophys. Acta | pmid:4554901 |
| Hokland BM and Bremer J | Metabolism and excretion of carnitine and acylcarnitines in the perfused rat kidney. | 1986 | Biochim. Biophys. Acta | pmid:3697382 |
| Egawa T et al. | Critical structural role of R481 in cytochrome c oxidase from Rhodobacter sphaeroides. | 2009 | Biochim. Biophys. Acta | pmid:19463779 |
| Richard E et al. | Genetic heterogeneity in propionic acidemia patients with alpha-subunit defects. Identification of five novel mutations, one of them causing instability of the protein. | 1999 | Biochim. Biophys. Acta | pmid:10101253 |
| Yoshikawa S et al. | Structural studies on bovine heart cytochrome c oxidase. | 2012 | Biochim. Biophys. Acta | pmid:22236806 |
| Emmanuel B | The relative contribution of propionate, and long-chain even-numbered fatty acids to the production of long-chain odd-numbered fatty acids in rumen bacteria. | 1978 | Biochim. Biophys. Acta | pmid:564207 |
| Desire B and Saint-Andre S | [Accelerating effect of heterocyclic quaternary ammonium salts on neutral ester hydrolysis by acetylcholinesterase and butyrylcholinesterase (author's transl)]. | 1981 | Biochim. Biophys. Acta | pmid:7260096 |
| Gens JS et al. | Different ionic conditions prompt NHE2 and NHE3 translocation to the plasma membrane. | 2007 | Biochim. Biophys. Acta | pmid:17303069 |
| Scaife JR and Tichivangana JZ | Short chain acyl-CoA synthetases in ovine rumen epithelium. | 1980 | Biochim. Biophys. Acta | pmid:7407228 |
| Clavero S et al. | Functional characterization of PCCA mutations causing propionic acidemia. | 2002 | Biochim. Biophys. Acta | pmid:12385775 |
| Kaila VR et al. | The identity of the transient proton loading site of the proton-pumping mechanism of cytochrome c oxidase. | 2011 | Biochim. Biophys. Acta | pmid:20831859 |
| Honig GR et al. | Hemoglobin F Lódź (G gamma I 44 Ser replaced by Arg). A newly identified variant from an American infant of Polish descent. | 1982 | Biochim. Biophys. Acta | pmid:6814491 |
| Benavides J et al. | Glycine transport in rat brain and liver mitochondria. | 1980 | Biochim. Biophys. Acta | pmid:7388024 |
| Jacobson G et al. | Human pituitary thyrotropin. Isolation of alpha and beta subunits by hydrophobic interaction chromatography. | 1978 | Biochim. Biophys. Acta | pmid:708778 |
| Hellwig P et al. | Spectroscopic study on the communication between a heme a3 propionate, Asp399 and the binuclear center of cytochrome c oxidase from Paracoccus denitrificans. | 2008 | Biochim. Biophys. Acta | pmid:18078804 |
| Kaur S et al. | Dimorphism-associated changes in intracellular pH of Candida albicans. | 1988 | Biochim. Biophys. Acta | pmid:2904280 |
| Ford SH | Amidation of, and (R)-1-amino-2-propanol attachment to, the corrin ring during vitamin B-12 biosynthesis by Clostridium tetanomorphum extracts. | 1985 | Biochim. Biophys. Acta | pmid:4027268 |
| Trotter PJ and Storch J | 3-[p-(6-phenyl)-1,3,5-hexatrienyl]phenylpropionic acid (PA-DPH): characterization as a fluorescent membrane probe and binding to fatty acid binding proteins. | 1989 | Biochim. Biophys. Acta | pmid:2742883 |
| Al-Lahham SH et al. | Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms. | 2010 | Biochim. Biophys. Acta | pmid:20691280 |