| MeSH term | MeSH ID | Detail |
|---|---|---|
| Gingival Diseases | D005882 | 1 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Glycosuria | D006029 | 10 associated lipids |
| Growth Disorders | D006130 | 5 associated lipids |
| Cardiomegaly | D006332 | 31 associated lipids |
| Heart Failure | D006333 | 36 associated lipids |
| Hemoglobinopathies | D006453 | 7 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Gastrointestinal Hemorrhage | D006471 | 27 associated lipids |
| Homocystinuria | D006712 | 2 associated lipids |
propionic acid
propionic acid is a lipid of Fatty Acyls (FA) class. Propionic acid is associated with abnormalities such as Epilepsy, Infection, Tuberculosis, Alkalosis and Ischemia. The involved functions are known as Uptake, Biosynthetic Pathways, Methylation, Protein Overexpression and Biochemical Pathway. Propionic acid often locates in Body tissue, Cytoplasmic matrix, Membrane, Protoplasm and Extracellular. The associated genes with propionic acid are TRIO gene, TRRAP gene, SLC5A8 gene, SLC33A1 gene and Homologous Gene. The related lipids are Fatty Acids, Propionate, butyrate, Valerates and mycocerosic acid.
Cross Reference
Introduction
To understand associated biological information of propionic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with propionic acid?
propionic acid is suspected in Propionic acidemia, Ischemia, Infection, Ulcerative Colitis, Alkalosis, Methylmalonic acidemia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with propionic acid
PubChem Associated disorders and diseases
What pathways are associated with propionic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with propionic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with propionic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with propionic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with propionic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with propionic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with propionic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Burnard DM and MacVicar BA | Electrophysiological properties of glial cells are altered by propionate and barium-tetraethylammonium (TEA). | 1987 | Proc. West. Pharmacol. Soc. | pmid:2442772 |
| Ninio DM and Saint DA | The role of stretch-activated channels in atrial fibrillation and the impact of intracellular acidosis. | Prog. Biophys. Mol. Biol. | pmid:18367236 | |
| Juszczak GR and Swiergiel AH | Properties of gap junction blockers and their behavioural, cognitive and electrophysiological effects: animal and human studies. | 2009 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:19162118 |
| Appleton RA and Brown K | Conformational requirements at the prostaglandin cyclooxygenase receptor site: a template for designing non-steroidal anti-inflammatory drugs. | 1979 | Prostaglandins | pmid:118488 |
| Powell JG and Cochrane RL | The effects of a number of non-steroidal anti-inflammatory compounds on parturition in the rat. | 1982 | Prostaglandins | pmid:7202240 |
| Mustata G and Briggs JM | Cluster analysis of water molecules in alanine racemase and their putative structural role. | 2004 | Protein Eng. Des. Sel. | pmid:15115851 |
| Miller GT et al. | Expression of Pseudomonas stutzeri Zobell cytochrome c-551 and its H47A variant in Escherichia coli. | 2003 | Protein Expr. Purif. | pmid:12767816 |
| Takahashi K et al. | Expression and characterization of frog peptidylglycine alpha-hydroxylating monooxygenase. | 2003 | Protein Expr. Purif. | pmid:12509982 |
| Sode K et al. | Propionate sensor using coenzyme-A transferase and acyl-CoA oxidase. | 2008 | Protein Pept. Lett. | pmid:18855748 |
| Qian C et al. | Effects of charged amino-acid mutation on the solution structure of cytochrome b(5) and binding between cytochrome b(5) and cytochrome c. | 2001 | Protein Sci. | pmid:11714912 |
| Stephenson JR et al. | Role of aspartate 400, arginine 262, and arginine 401 in the catalytic mechanism of human coproporphyrinogen oxidase. | 2007 | Protein Sci. | pmid:17242372 |
| Smith LJ et al. | Molecular dynamics simulations of Hydrogenobacter thermophilus cytochrome c552: comparisons of the wild-type protein, a b-type variant, and the apo state. | 2006 | Proteins | pmid:16981201 |
| Bento I et al. | Molecular basis for redox-Bohr and cooperative effects in cytochrome c3 from Desulfovibrio desulfuricans ATCC 27774: crystallographic and modeling studies of oxidized and reduced high-resolution structures at pH 7.6. | 2004 | Proteins | pmid:14705030 |
| Fufezan C et al. | Ligand preference and orientation in b- and c-type heme-binding proteins. | 2008 | Proteins | pmid:18491383 |
| Stjernschantz E et al. | Structural rationalization of novel drug metabolizing mutants of cytochrome P450 BM3. | 2008 | Proteins | pmid:17957765 |
| Simanshu DK et al. | Crystal structures of Salmonella typhimurium propionate kinase and its complex with Ap4A: evidence for a novel Ap4A synthetic activity. | 2008 | Proteins | pmid:17894350 |
| Zubieta C et al. | Identification and structural characterization of heme binding in a novel dye-decolorizing peroxidase, TyrA. | 2007 | Proteins | pmid:17654547 |
| Diedrich M et al. | Brain region specific mitophagy capacity could contribute to selective neuronal vulnerability in Parkinson's disease. | 2011 | Proteome Sci | pmid:21943346 |
| Santos PM and Sá-Correia I | Adaptation to beta-myrcene catabolism in Pseudomonas sp. M1: an expression proteomics analysis. | 2009 | Proteomics | pmid:19798672 |
| Zhang J et al. | Protein profile in neuroblastoma cells incubated with S- and R-enantiomers of ibuprofen by iTRAQ-coupled 2-D LC-MS/MS analysis: possible action of induced proteins on Alzheimer's disease. | 2008 | Proteomics | pmid:18351690 |
| Murphy ER et al. | Impulsive behaviour induced by both NMDA receptor antagonism and GABAA receptor activation in rat ventromedial prefrontal cortex. | 2012 | Psychopharmacology (Berl.) | pmid:22101355 |
| Pałucha-Poniewiera A et al. | On the mechanism of the antidepressant-like action of group II mGlu receptor antagonist, MGS0039. | 2010 | Psychopharmacology (Berl.) | pmid:20703449 |
| Gonzalez NS et al. | The fate of P2Y-related orphan receptors: GPR80/99 and GPR91 are receptors of dicarboxylic acids. | 2004 | Purinergic Signal. | pmid:18404396 |
| Burnstock G and De Ryck M | UCB Pharma research day-25 October 2007 'Glia-neuron interactions and purinergic receptors in neurological disorders'. | 2008 | Purinergic Signal. | pmid:18368536 |
| Anil MH and Forbes JM | The roles of hepatic nerves in the reduction of food intake as a consequence of intraportal sodium propionate administration in sheep. | 1988 | Q J Exp Physiol | pmid:3174914 |
| Salem N et al. | PET imaging of hepatocellular carcinoma with 2-deoxy-2[18F]fluoro-D-glucose, 6-deoxy-6[18F] fluoro-D-glucose, [1-11C]-acetate and [N-methyl-11C]-choline. | 2009 | Q J Nucl Med Mol Imaging | pmid:19039303 |
| Häggström I et al. | Semi-automatic tumour segmentation by selective navigation in a three-parameter volume, obtained by voxel-wise kinetic modelling of 11C-acetate. | Radiat Prot Dosimetry | pmid:20200103 | |
| Mori Y et al. | Autoradiographic study on the distribution of suprofen in rats of both sexes. | 1984 | Radioisotopes | pmid:6473839 |
| Mori Y et al. | Distribution of suprofen in rats of both sexes. | 1984 | Radioisotopes | pmid:6473840 |
| Mori Y et al. | Syntheses of deuterated phenylpropionic acid derivatives. | 1983 | Radioisotopes | pmid:6675056 |
| Seppälä J et al. | Carbon-11 acetate PET/CT based dose escalated IMRT in prostate cancer. | 2009 | Radiother Oncol | pmid:19766336 |
| Cavaggioni A et al. | The scent of urine spots of male mice, Mus musculus: Changes in chemical composition over time. | 2006 | Rapid Commun. Mass Spectrom. | pmid:17120277 |
| Halket JM et al. | Deconvolution gas chromatography/mass spectrometry of urinary organic acids--potential for pattern recognition and automated identification of metabolic disorders. | 1999 | Rapid Commun. Mass Spectrom. | pmid:10097403 |
| da Graça Gama Melão M et al. | Determination of aerobic-anaerobic metabolism-related compounds in a Chaoborus flavicans population by infusion ion trap mass spectrometry of extracts of individual larvae. | 2006 | Rapid Commun. Mass Spectrom. | pmid:16482528 |
| Norwood DL et al. | Application of continuous-flow liquid chromatography/fast-atom bombardment mass spectrometry to the analysis of diagnostic acylcarnitines in human urine. | 1988 | Rapid Commun. Mass Spectrom. | pmid:2577839 |
| Ferchaud-Roucher V et al. | Solid-phase microextraction method for carbon isotopic analysis of volatile carboxylic acids in human plasma by gas chromatography/combustion/isotope ratio mass spectrometry. | 2006 | Rapid Commun. Mass Spectrom. | pmid:17083131 |
| Semchyshyn HM et al. | Acetate but not propionate induces oxidative stress in bakers' yeast Saccharomyces cerevisiae. | 2011 | Redox Rep. | pmid:21605494 |
| Yonezawa T et al. | Short-chain fatty acid signaling pathways in bovine mammary epithelial cells. | 2009 | Regul. Pept. | pmid:19101595 |
| Carman RJ et al. | Antibiotics in the human food chain: establishing no effect levels of tetracycline, neomycin, and erythromycin using a chemostat model of the human colonic microflora. | 2005 | Regul. Toxicol. Pharmacol. | pmid:16129531 |
| Grizard J and Szczygiel M | Plasma insulin and insulin kinetics in growing sheep. Influence of age and diet. | 1983 | Reprod Nutr Dev | pmid:6342076 |
| Jouany JP and Senaud J | [Effect of rumen ciliates on the digestive utilization of various carbohydrate-rich diets and on the end-products formed in the rumen. II. Utilization of inulin, saccharose and lactose]. | 1983 | Reprod Nutr Dev | pmid:6412334 |
| Thivend P and Jouany JP | Effect of lasalocid sodium on rumen fermentation and digestion in sheep. | 1983 | Reprod Nutr Dev | pmid:6648029 |
| Demigné C et al. | [Findings on intermediate metabolism in ruminants]. | 1988 | Reprod Nutr Dev | pmid:3281195 |
| Rémésy C et al. | Origin and utilization of volatile fatty acids in the rat. | 1980 | Reprod Nutr Dev | pmid:7349486 |
| Candau M and Kone L | [Influence of thiamine on bacterial proteosynthesis in sheep]. | 1980 | Reprod Nutr Dev | pmid:7349505 |
| Focant M | [Feeding behavior, rumination, reticulo-ruminal fermentation and plasma volatile fatty acids, compared in goats and sheep; influence of the diet]. | 1984 | Reprod Nutr Dev | pmid:6729237 |
| Vo TT et al. | Di-(2 ethylhexyl) phthalate and flutamide alter gene expression in the testis of immature male rats. | 2009 | Reprod. Biol. Endocrinol. | pmid:19781091 |
| Janowski T et al. | Combined gnRH and PGF2alpha application in cows with endometritis puerperalis treated with antibiotics. | 2001 | Reprod. Domest. Anim. | pmid:11885741 |
| Sano H and Terashima Y | The effect of supplemental propionate on insulin responsiveness to glucose and tissue responsiveness to insulin in relation to feeding in sheep. | 1998 Jan-Feb | Reprod. Nutr. Dev. | pmid:9606751 |
| Hurtaud C et al. | Effects of level and type of energy source (volatile fatty acids or glucose) on milk yield, composition and coagulating properties in dairy cows. | 1998 May-Jun | Reprod. Nutr. Dev. | pmid:9698283 |
| Sano H and Fujita T | Effect of supplemental calcium propionate on insulin action to blood glucose metabolism in adult sheep. | 2006 Jan-Feb | Reprod. Nutr. Dev. | pmid:16438911 |
| Adjiri D et al. | [In vitro simulation of rabbit cecal fermentation in a semi- continuous flow fermentor. I. Role of food substrate pretreatment]. | 1992 | Reprod. Nutr. Dev. | pmid:1418397 |
| Gidenne T and Bellier R | [In vivo study of cecal fermentation activity in the rabbit. Completion and validation of a new technique for cecal cannulation]. | 1992 | Reprod. Nutr. Dev. | pmid:1418398 |
| Kumar N et al. | Effect of different levels and sources of zinc supplementation on quantitative and qualitative semen attributes and serum testosterone level in crossbred cattle (Bos indicus x Bos taurus) bulls. | 2006 Nov-Dec | Reprod. Nutr. Dev. | pmid:17169313 |
| Broudiscou LP and Lassalas B | Effects of Lavandula officinalis and Equisetum arvense dry extracts and isoquercitrin on the fermentation of diets varying in forage contents by rumen microorganisms in batch culture. | 2000 Sep-Oct | Reprod. Nutr. Dev. | pmid:11140815 |
| Fiems LO et al. | Effect of a viable yeast culture on digestibility and rumen fermentation in sheep fed different types of diets. | 1993 | Reprod. Nutr. Dev. | pmid:8447942 |
| Fujita T et al. | Combined effect of salinomycin and feeding on whole body glucose kinetics in sheep fed a high-concentrate diet. | Reprod. Nutr. Dev. | pmid:17107640 | |
| Demeyer DI et al. | Attempted induction of reductive acetogenesis into the rumen fermentation in vitro. | 1996 | Reprod. Nutr. Dev. | pmid:8766728 |
| Doreau M and Chilliard Y | Effects of ruminal or postruminal fish oil supplementation on intake and digestion in dairy cows. | 1997 | Reprod. Nutr. Dev. | pmid:9115590 |
| Ortega HH et al. | Developmental programming: prenatal androgen excess disrupts ovarian steroid receptor balance. | 2009 | Reproduction | pmid:19261835 |
| Hanaki Y et al. | Effect of 3-(2,2,2-trimethylhydrazinium) propionate, gamma-butyrobetaine hydroxylase inhibitor, on isoproterenol-induced mitochondrial dysfunction. | 1989 | Res. Commun. Chem. Pathol. Pharmacol. | pmid:2546223 |
| Blank ML et al. | Structural features of platelet activating factor (1-alkyl-2-acetyl-sn-glycero-3-phosphocholine) required for hypotensive and platelet serotonin responses. | 1982 | Res. Commun. Chem. Pathol. Pharmacol. | pmid:7146619 |
| Dixon R and Crews T | An 125I-radioimmunoassay for the determination of the anticonvulsant agent clonazepam directly in plasma. | 1977 | Res. Commun. Chem. Pathol. Pharmacol. | pmid:928948 |
| De Cima S et al. | An acetyl-CoA synthetase not encoded by the facA gene is expressed under carbon starvation in Phycomyces blakesleeanus. | 2005 Jun-Jul | Res. Microbiol. | pmid:15921892 |
| Rúa J et al. | Glycogen and trehalose mobilization by acetic acid in Phycomyces blakesleeanus: dependence on the anion form. | 2008 | Res. Microbiol. | pmid:18359201 |
| Kholti A et al. | A new mini-transposon for in vivo protein epitope tagging: application to Burkholderia multivorans. | Res. Microbiol. | pmid:12892852 | |
| Grabowski A et al. | Characterization of long-chain fatty-acid-degrading syntrophic associations from a biodegraded oil reservoir. | 2005 | Res. Microbiol. | pmid:15939576 |
| Rattenbury JM et al. | Effect of propionic acid on urea synthesis by sheep liver. | 1983 | Res. Vet. Sci. | pmid:6622846 |
| Kendall PE and McLeay LM | Excitatory effects of volatile fatty acids on the in vitro motility of the rumen of sheep. | 1996 | Res. Vet. Sci. | pmid:8819185 |
| Tsiloyiannis VK et al. | The effect of organic acids on the control of porcine post-weaning diarrhoea. | 2001 | Res. Vet. Sci. | pmid:11676629 |
| Blum JW et al. | Metabolic effects of fasting in steers. | 1981 | Res. Vet. Sci. | pmid:7313312 |
| Calveyra JC et al. | Effect of organic acids and mannanoligosaccharide on excretion of Salmonella typhimurium in experimentally infected growing pigs. | 2012 | Res. Vet. Sci. | pmid:21944831 |
| Martineau B and Laflamme DP | Effect of diet on markers of intestinal health in dogs. | 2002 | Res. Vet. Sci. | pmid:12076118 |
| Weekes TE | Role of the rumen mucosa in the sheep: relative changes in weight, and in the ability to metabolize propionate, during pregnancy and lactation. | 1971 | Res. Vet. Sci. | pmid:5558543 |
| Gröhn Y | Propionate loading test for liver function in spontaneously ketotic dairy cows. | 1985 | Res. Vet. Sci. | pmid:4035089 |
| Strobel W et al. | Topical nasal steroid treatment does not improve CPAP compliance in unselected patients with OSAS. | 2011 | Respir Med | pmid:21129944 |
| Barnes NC et al. | Initiation of maintenance treatment with salmeterol/fluticasone propionate 50/100 microg bd versus fluticasone propionate 100 microg bd alone in patients with persistent asthma: integrated analysis of four randomised trials. | 2007 | Respir Med | pmid:17689947 |
| Persson CG and Uller L | Resolution of cell-mediated airways diseases. | 2010 | Respir. Res. | pmid:20540713 |
| Siganaki M et al. | Deregulation of apoptosis mediators' p53 and bcl2 in lung tissue of COPD patients. | 2010 | Respir. Res. | pmid:20423464 |
| Lötvall J et al. | Inhaled steroid/long-acting beta 2 agonist combination products provide 24 hours improvement in lung function in adult asthmatic patients. | 2006 | Respir. Res. | pmid:16919161 |
| MacRedmond RE et al. | Epithelial expression of TLR4 is modulated in COPD and by steroids, salmeterol and cigarette smoke. | 2007 | Respir. Res. | pmid:18034897 |
| Valotis A and Högger P | Human receptor kinetics and lung tissue retention of the enhanced-affinity glucocorticoid fluticasone furoate. | 2007 | Respir. Res. | pmid:17650349 |
| Houghton CM et al. | Comparison of the effects of salmeterol/fluticasone propionate with fluticasone propionate on airway physiology in adults with mild persistent asthma. | 2007 | Respir. Res. | pmid:17629923 |
| Ni YF et al. | Histone deacetylase inhibitor, butyrate, attenuates lipopolysaccharide-induced acute lung injury in mice. | 2010 | Respir. Res. | pmid:20302656 |
| Kankaanranta H et al. | Add-on therapy options in asthma not adequately controlled by inhaled corticosteroids: a comprehensive review. | 2004 | Respir. Res. | pmid:15509300 |
| Stambuk B et al. | [Use of non-steroidal antiinflammatory drugs in specialty polyclinic practice]. | 1989 | Reumatizam | pmid:2491403 |
| Sánchez-Ródenas L et al. | [Infant boy with propionic acidemia: anesthetic implications]. | 2005 Aug-Sep | Rev Esp Anestesiol Reanim | pmid:16200924 |
| Benito Quintela F | [The propionic ester of erythromycin. Its value in dento-oral infections]. | 1982 Jul-Aug | Rev Esp Estomatol | pmid:6963709 |
| Simon C et al. | [Hepatic involvement induced by erythromycin propionate]. | 1985 | Rev Med Interne | pmid:4001646 |
| Nitzulescu V and Popescu A | [Propionylerythromycin in the treatment of giardiasis]. | 1980 Jul-Sep | Rev Pediatr Obstet Ginecol Pediatr | pmid:6781038 |
| Sonder E et al. | Inactivation of foot and mouth disease virus in skimmed milk with propionic acid, citric acid and hydrogen peroxide. | 1990 | Rev. - Off. Int. Epizoot. | pmid:1966751 |
| Benavides J and Ugarte M | [Molecular pathology of the hyperglycinemias]. | 1982 | Rev. Esp. Fisiol. | pmid:6128772 |
| Moore TL and Dorner RW | Separation and characterization of complement-fixing immune complexes in juvenile rheumatoid arthritis patients. | 1986 | Rheumatol. Int. | pmid:3532285 |
| Groeneboer S et al. | Optimized alkylated cyclodextrin polysulphates with reduced risks on thromboembolic accidents improve osteoarthritic chondrocyte metabolism. | 2011 | Rheumatology (Oxford) | pmid:21345936 |
| Marcucci M and Panattoni A | [Dental clinical trial of an erythromycin propionate preparation]. | 1981 | Riv Ital Stomatol | pmid:7036325 |
| Pappalardo G et al. | [Clinical experimental research on the use of 2-(3-benzoylphenyl) propionic acid, or Ketoprofen, an adjuvant of antibiotic action in oral surgery]. | 1978 Jul-Aug | Riv Ital Stomatol | pmid:368951 |
| Ohura T | [Propionic acidemia]. | 1998 | Ryoikibetsu Shokogun Shirizu | pmid:9590046 |
| Matsubara Y | [Acidemia, propionic]. | 2001 | Ryoikibetsu Shokogun Shirizu | pmid:11462351 |
| Davidson JS et al. | Studies on cultured fibroblasts in a case of methylmalonic aciduria. | 1984 | S. Afr. Med. J. | pmid:6141644 |
| Sass AM et al. | Diversity of Bacillus-like organisms isolated from deep-sea hypersaline anoxic sediments. | 2008 | Saline Syst. | pmid:18541011 |