propionic acid

propionic acid is a lipid of Fatty Acyls (FA) class. Propionic acid is associated with abnormalities such as Epilepsy, Infection, Tuberculosis, Alkalosis and Ischemia. The involved functions are known as Uptake, Biosynthetic Pathways, Methylation, Protein Overexpression and Biochemical Pathway. Propionic acid often locates in Body tissue, Cytoplasmic matrix, Membrane, Protoplasm and Extracellular. The associated genes with propionic acid are TRIO gene, TRRAP gene, SLC5A8 gene, SLC33A1 gene and Homologous Gene. The related lipids are Fatty Acids, Propionate, butyrate, Valerates and mycocerosic acid.

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Introduction

To understand associated biological information of propionic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with propionic acid?

propionic acid is suspected in Propionic acidemia, Ischemia, Infection, Ulcerative Colitis, Alkalosis, Methylmalonic acidemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with propionic acid

MeSH term MeSH ID Detail
Puberty, Delayed D011628 1 associated lipids
Corynebacterium Infections D003354 7 associated lipids
Opportunistic Infections D009894 8 associated lipids
Androgen-Insensitivity Syndrome D013734 1 associated lipids
Eczema D004485 4 associated lipids
Zoonoses D015047 3 associated lipids
Vasculitis, Leukocytoclastic, Cutaneous D018366 5 associated lipids
Keratosis D007642 9 associated lipids
Telangiectasis D013684 2 associated lipids
Mitochondrial Diseases D028361 25 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Placenta, Retained D018457 3 associated lipids
Constipation D003248 8 associated lipids
Ileitis D007079 2 associated lipids
Carcinoma, Embryonal D018236 8 associated lipids
Parturient Paresis D010319 2 associated lipids
Ostertagiasis D010029 2 associated lipids
Ergotism D004881 4 associated lipids
Liver Abscess D008100 6 associated lipids
Dysautonomia, Familial D004402 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with propionic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with propionic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with propionic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with propionic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with propionic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with propionic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with propionic acid

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Per page 10 20 50 100 | Total 6372
Authors Title Published Journal PubMed Link
Scott DA et al. Ca2+ storage in Trypanosoma brucei: the influence of cytoplasmic pH and importance of vacuolar acidity. 1995 Biochem. J. pmid:7575411
O'Keeffe DT and Anthony C The two cytochromes c in the facultative methylotroph Pseudomonas am1. 1980 Biochem. J. pmid:6263253
Arinze IJ and Rowley DL Gluconeogenesis by isolated guinea-pig liver parenchymal cells. 1975 Biochem. J. pmid:177003
Clark MG et al. Gluconeogenesis in isolated intact lamb liver cells. Effects of glucagon and butyrate. 1976 Biochem. J. pmid:949349
Hashimoto S and Hayakawa S Microbiological degradation of bile acids. Metabolites formed from 3-(3a alpha-hexahydro-7a beta-methyl-1,5-dioxoindan-4 alpha-yl) propionic acid by Streptomyces rubescens. 1977 Biochem. J. pmid:883963
Lomax MA et al. The control of fatty acid metabolism in liver cells from fed and starved sheep. 1983 Biochem. J. pmid:6615480
Ghosh NK et al. Induction of human choriogonadotropin in heLa-cell cultures by aliphatic monocarboxylates and inhibitors of deoxyribonucleic acid synthesis. 1977 Biochem. J. pmid:911320
Scholem RD and Brown GK Metabolism of malonic semialdehyde in man. 1983 Biochem. J. pmid:6418146
Seehra JS et al. Anaerobic and aerobic coproporphyrinogen III oxidases of Rhodopseudomonas spheroides. Mechanism and stereochemistry of vinyl group formation. 1983 Biochem. J. pmid:6603215
Jia Y et al. Kinetics and product analysis of the reaction catalysed by recombinant homoaconitase from Thermus thermophilus. 2006 Biochem. J. pmid:16524361
Schwab MA et al. Secondary mitochondrial dysfunction in propionic aciduria: a pathogenic role for endogenous mitochondrial toxins. 2006 Biochem. J. pmid:16686602
Girvan HM et al. Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3. 2010 Biochem. J. pmid:20180779
KENTEN RH The oxidation of beta-(3-indolyl) propionic acid and gamma-(3-indolyl)-n-butyric acid by peroxidase and Mn2+. 1955 Biochem. J. pmid:13269367
Williams DL et al. Metabolic effects of propionate administration to normal and vitamin B12-deficient rats. 1971 Biochem. J. pmid:5116531
Nyhan WL et al. Tiglicaciduria in propionicacidaemia. 1972 Biochem. J. pmid:5073234
Ryan JP and Ryan H The role of intracellular pH in the regulation of cation exchanges in yeast. 1972 Biochem. J. pmid:4563763
Malaisse WJ et al. Enzyme-to-enzyme channelling of Krebs cycle metabolic intermediates in Caco-2 cells exposed to [2-13c]propionate. 1996 Biochem. J. pmid:8760374
Jones A and Turner JM Microbial metabolism of amino alcohols. 1-Aminopropan-2-ol and ethanolamine metabolism via propionaldehyde and acetaldehyde in a species of Pseudomonas. 1973 Biochem. J. pmid:4723219
Narumi K et al. Biosynthesis of a mycobacterial lipopolysaccharide. Incorporation of (14C)acyl groups by whole cells in vivo. 1973 Biochem. J. pmid:4725042
ANNISON EF et al. THE METABOLISM OF ACETIC ACID, PROPIONIC ACID AND BUTYRIC ACID IN SHEEP. 1963 Biochem. J. pmid:14063864
Hiltunen JK Metabolic effects of pent-4-enoate in isolated perfused rat heart. 1978 Biochem. J. pmid:637839
Grunnet N and Katz J Effects of ammonia and norvaline on lactate metabolism by hepatocytes from starved rats. The use of 14C-labelled lactate in studies of hepatic gluconeogenesis. 1978 Biochem. J. pmid:687361
Killilea SD et al. Structures and apoprotein linkages of phycoerythrobilin and phycocyanobilin. 1980 Biochem. J. pmid:7396852
Lomax MA et al. The effect of fatty acids and starvation on the metabolism of gluconeogenic precursors by isolated sheep liver cells. 1986 Biochem. J. pmid:3827848
Killilea SD and O'Carra P Structure and apoprotein linkages of phycourobilin. 1985 Biochem. J. pmid:3838665
Burger-van Paassen N et al. The regulation of intestinal mucin MUC2 expression by short-chain fatty acids: implications for epithelial protection. 2009 Biochem. J. pmid:19228118
Iwaki A and Izawa S Acidic stress induces the formation of P-bodies, but not stress granules, with mild attenuation of bulk translation in Saccharomyces cerevisiae. 2012 Biochem. J. pmid:22686455
Sumegi B et al. Metabolism of [3-13C]pyruvate and [3-13C]propionate in normal and ischaemic rat heart in vivo: 1H- and 13C-NMR studies. 1995 Biochem. J. pmid:7492338
Koshihara Y et al. Effect of sodium n-butyrate on induction of prostaglandin synthase activity in cloned mastocytoma P-815 2-E-6 cells. 1981 Biochem. J. pmid:6796055
Arinze IJ et al. Effect of methylamalonic acid on gluconeogenesis in isolated rat and guinea-pig hepatocytes. 1979 Biochem. J. pmid:540062
Giudici TA et al. Methylmalonic and propionic acidemias: lipid profiles of normal and affected human skin fibroblasts incubated with [1-14C]propionate. 1986 Biochem. Med. Metab. Biol. pmid:2872907
Marsden D et al. Anabolic effect of human growth hormone: management of inherited disorders of catabolic pathways. 1994 Biochem. Med. Metab. Biol. pmid:7993663
Michalik M and Bryła J Inhibitory effect of gentamicin on gluconeogenesis from pyruvate, propionate, and lactate in isolated rabbit kidney-cortex tubules. 1987 Biochem. Med. Metab. Biol. pmid:3663396
Dutra JC et al. Effects of methylmalonate and propionate on uptake of glucose and ketone bodies in vitro by brain of developing rats. 1991 Biochem. Med. Metab. Biol. pmid:2015109
de Mello CF et al. Effects of methylmalonate and propionate on [3H]glutamate binding, adenylate cyclase activity and lipid synthesis in rat cerebral cortex. 1997 Biochem. Mol. Biol. Int. pmid:9305532
Larrey D et al. Effects of erythromycin on hepatic drug-metabolizing enzymes in humans. 1983 Biochem. Pharmacol. pmid:6838653
Wang H et al. Characterizing the effect of UDP-glucuronosyltransferase (UGT) 2B7 and UGT1A9 genetic polymorphisms on enantioselective glucuronidation of flurbiprofen. 2011 Biochem. Pharmacol. pmid:21856293
Larrey D et al. Formation of inactive cytochrome P-450 Fe(II)-metabolite complexes with several erythromycin derivatives but not with josamycin and midecamycin in rats. 1983 Biochem. Pharmacol. pmid:6860368
Otagiri M et al. Binding of pirprofen to human serum albumin studied by dialysis and spectroscopy techniques. 1989 Biochem. Pharmacol. pmid:2910295
Nambi P et al. Induction of functional beta-adrenergic receptors in rat aortic smooth muscle cells by sodium butyrate. 1986 Biochem. Pharmacol. pmid:3022740
Krahenbuhl S and Brass EP Inhibition of hepatic propionyl-CoA synthetase activity by organic acids. Reversal of propionate inhibition of pyruvate metabolism. 1991 Mar 15-Apr 1 Biochem. Pharmacol. pmid:2009071
Muramatsu M et al. Enhancement of affinity to receptors in the esterified glucocorticoid, hydrocortisone 17-butyrate 21-propionate (HBP), in the rat liver. 1986 Biochem. Pharmacol. pmid:3718538
Sumegi B et al. Is there tight channelling in the tricarboxylic acid cycle metabolon? 1991 Biochem. Soc. Trans. pmid:1794455
Sherry AD et al. Orientation-conserved transfer of symmetric Krebs cycle intermediates in mammalian tissue. 1994 Biochemistry pmid:7910760
Liu GY et al. Ionic strength dependence of cytochrome c structure and Trp-59 H/D exchange from ultraviolet resonance Raman spectroscopy. 1989 Biochemistry pmid:2548599
Efimov I et al. Structure and reaction mechanism in the heme dioxygenases. 2011 Biochemistry pmid:21361337
Mascaretti OA et al. Biosynthesis of the macrolide antibiotic chlorothricin. 1981 Biochemistry pmid:7011379
Raman CS et al. Crystal structure of nitric oxide synthase bound to nitro indazole reveals a novel inactivation mechanism. 2001 Biochemistry pmid:11695891
Stayton PS et al. Putidaredoxin competitively inhibits cytochrome b5-cytochrome P-450cam association: a proposed molecular model for a cytochrome P-450cam electron-transfer complex. 1989 Biochemistry pmid:2690937
Singh R et al. Unprecedented peroxidase-like activity of Rhodnius prolixus nitrophorin 2: identification of the [FeIV=O Por•]+ and [FeIV=O Por](Tyr38•) intermediates and their role(s) in substrate oxidation. 2010 Biochemistry pmid:20726527