propionic acid

propionic acid is a lipid of Fatty Acyls (FA) class. Propionic acid is associated with abnormalities such as Epilepsy, Infection, Tuberculosis, Alkalosis and Ischemia. The involved functions are known as Uptake, Biosynthetic Pathways, Methylation, Protein Overexpression and Biochemical Pathway. Propionic acid often locates in Body tissue, Cytoplasmic matrix, Membrane, Protoplasm and Extracellular. The associated genes with propionic acid are TRIO gene, TRRAP gene, SLC5A8 gene, SLC33A1 gene and Homologous Gene. The related lipids are Fatty Acids, Propionate, butyrate, Valerates and mycocerosic acid.

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Introduction

To understand associated biological information of propionic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with propionic acid?

propionic acid is suspected in Propionic acidemia, Ischemia, Infection, Ulcerative Colitis, Alkalosis, Methylmalonic acidemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with propionic acid

MeSH term MeSH ID Detail
Puberty, Delayed D011628 1 associated lipids
Corynebacterium Infections D003354 7 associated lipids
Opportunistic Infections D009894 8 associated lipids
Androgen-Insensitivity Syndrome D013734 1 associated lipids
Eczema D004485 4 associated lipids
Zoonoses D015047 3 associated lipids
Vasculitis, Leukocytoclastic, Cutaneous D018366 5 associated lipids
Keratosis D007642 9 associated lipids
Telangiectasis D013684 2 associated lipids
Mitochondrial Diseases D028361 25 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Placenta, Retained D018457 3 associated lipids
Constipation D003248 8 associated lipids
Ileitis D007079 2 associated lipids
Carcinoma, Embryonal D018236 8 associated lipids
Parturient Paresis D010319 2 associated lipids
Ostertagiasis D010029 2 associated lipids
Ergotism D004881 4 associated lipids
Liver Abscess D008100 6 associated lipids
Dysautonomia, Familial D004402 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with propionic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with propionic acid?

Related references are published most in these journals:

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What functions are associated with propionic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with propionic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with propionic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with propionic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with propionic acid

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Authors Title Published Journal PubMed Link
Smith RM and Osborne-White WS Synthesis of phosphoenolpyruvate from propionate in sheep liver. 1971 Biochem. J. pmid:4331860
Gaitonde MK Conversion of [U-14C]threonine into 14C-labelled amino acids in the brain of thiamin-deficient rats. 1975 Biochem. J. pmid:1180921
Biebuyck JF et al. The effects of halothane (2-bromo-2-chloro-1,1,1-trifluoroethane) on glycolysis and biosynthetic processes of the isolated perfused rat liver. 1972 Biochem. J. pmid:4344008
Wilkemeyer MF et al. Primary structure and activity of mouse methylmalonyl-CoA mutase. 1990 Biochem. J. pmid:1978672
Hancock FE et al. The 3H-labelling of bilirubin. 1976 Biochem. J. pmid:962882
Arinze IJ and Rowley DL Gluconeogenesis by isolated guinea-pig liver parenchymal cells. 1975 Biochem. J. pmid:177003
Ash R and Baird GD Activation of volatile fatty acids in bovine liver and rumen epithelium. Evidence for control by autoregulation. 1973 Biochem. J. pmid:4359516
Faulkner A and Turner JM Microbial metabolism of amino alcohols. Aminoacetone metabolism via 1-aminopropan-2-ol in Pseudomonas sp. N.C.I.B. 8858. 1974 Biochem. J. pmid:4362743
Young OA and Anderson JW The enzymology of short-chain fatty acyl-coenzyme A synthetase from seeds of Pinus radiata. Kinetic studies and a proposed reaction mechanism. 1974 Biochem. J. pmid:4370933
Young OA and Anderson JW Properties and substrate specificity of some reactions catalysed by a short-chain fatty acyl-coenzyme A synthetase from seeds of Pinus radiata. 1974 Biochem. J. pmid:4370976
Smith AJ and Lucas C Propionate resistance in blue-green algae. 1971 Biochem. J. pmid:5003469
Elliott KR and Pogson CI The effects of starvation and experimental diabetes on phosphoenol-pyruvate carboxykinase in the guinea pig. 1977 Biochem. J. pmid:141929
Woodnutt G and Parker DS Rabbit liver acetyl-CoA synthetase. 1978 Biochem. J. pmid:33661
Evans CT et al. [13C]propionate oxidation in wild-type and citrate synthase mutant Escherichia coli: evidence for multiple pathways of propionate utilization. 1993 Biochem. J. pmid:8098211
Brass EP and Beyerinck RA Effects of propionate and carnitine on the hepatic oxidation of short- and medium-chain-length fatty acids. 1988 Biochem. J. pmid:3134008
Sundqvist KE et al. Role of NADP+ (corrected)-linked malic enzymes as regulators of the pool size of tricarboxylic acid-cycle intermediates in the perfused rat heart. 1987 Biochem. J. pmid:3663104
Bell SC and Turner JM Bacterial catabolism of threonine. Threonine degradation initiated by l-threonine hydrolyase (deaminating) in a species of Corynebacterium. 1977 Biochem. J. pmid:16743051
Hartshorn RT and Moore GR A denaturation-induced proton-uptake study of horse ferricytochrome c. 1989 Biochem. J. pmid:2539812
Tonge P et al. Fourier-transform infra-red studies of the alkaline isomerization of mitochondrial cytochrome c and the ionization of carboxylic acids. 1989 Biochem. J. pmid:2539813
Baird GD et al. Net hepatic and splanchnic metabolism of lactate, pyruvate and propionate in dairy cows in vivo in relation to lactation and nutrient supply. 1980 Biochem. J. pmid:6989361
JAMES AT et al. The metabolism of propionic acid. 1956 Biochem. J. pmid:13382825
Malaisse WJ et al. Enzyme-to-enzyme channelling of Krebs cycle metabolic intermediates in Caco-2 cells exposed to [2-13c]propionate. 1996 Biochem. J. pmid:8760374
STORRY JE and ROOK JA EFFECT IN THE COW OF INTRARUMINAL INFUSIONS OF VOLATILE FATTY ACIDS AND OF LACTIC ACID ON THE SECRETION OF THE COMPONENT FATTY ACIDS OF THE MILK FAT AND ON THE COMPOSITION OF BLOOD. 1965 Biochem. J. pmid:14343134
Hayakawa S et al. Microbiological degradation of bile acids. Nitrogenous hexahydroindane derivatives formed from cholic acid by Streptomyces rubescens. 1976 Biochem. J. pmid:1016253
ANNISON EF et al. THE METABOLISM OF ACETIC ACID, PROPIONIC ACID AND BUTYRIC ACID IN SHEEP. 1963 Biochem. J. pmid:14063864
Jordan PM and Gibbs PN Mechanism of action of 5-aminolaevulinate dehydratase from human erythrocytes. 1985 Biochem. J. pmid:4004789
Hildmann B et al. Sodium ion/L-lactate co-transport in rabbit small-intestinal brush-border-membrane vesicles. 1980 Biochem. J. pmid:7370006
Gallegos AM et al. Structure and cholesterol domain dynamics of an enriched caveolae/raft isolate. 2004 Biochem. J. pmid:15149285
Hiltunen JK et al. Isolated rat heart mitochondria are able to metabolize pent-4-enoate to tricarboxylic acid-cycle intermediates. 1980 Biochem. J. pmid:7470030
Shepherd M and Hunter CN Transient kinetics of the reaction catalysed by magnesium protoporphyrin IX methyltransferase. 2004 Biochem. J. pmid:15239672
Giudici TA et al. Methylmalonic and propionic acidemias: lipid profiles of normal and affected human skin fibroblasts incubated with [1-14C]propionate. 1986 Biochem. Med. Metab. Biol. pmid:2872907
Marsden D et al. Anabolic effect of human growth hormone: management of inherited disorders of catabolic pathways. 1994 Biochem. Med. Metab. Biol. pmid:7993663
Michalik M and Bryła J Inhibitory effect of gentamicin on gluconeogenesis from pyruvate, propionate, and lactate in isolated rabbit kidney-cortex tubules. 1987 Biochem. Med. Metab. Biol. pmid:3663396
Dutra JC et al. Effects of methylmalonate and propionate on uptake of glucose and ketone bodies in vitro by brain of developing rats. 1991 Biochem. Med. Metab. Biol. pmid:2015109
de Mello CF et al. Effects of methylmalonate and propionate on [3H]glutamate binding, adenylate cyclase activity and lipid synthesis in rat cerebral cortex. 1997 Biochem. Mol. Biol. Int. pmid:9305532
Larrey D et al. Effects of erythromycin on hepatic drug-metabolizing enzymes in humans. 1983 Biochem. Pharmacol. pmid:6838653
Wang H et al. Characterizing the effect of UDP-glucuronosyltransferase (UGT) 2B7 and UGT1A9 genetic polymorphisms on enantioselective glucuronidation of flurbiprofen. 2011 Biochem. Pharmacol. pmid:21856293
Larrey D et al. Formation of inactive cytochrome P-450 Fe(II)-metabolite complexes with several erythromycin derivatives but not with josamycin and midecamycin in rats. 1983 Biochem. Pharmacol. pmid:6860368
Otagiri M et al. Binding of pirprofen to human serum albumin studied by dialysis and spectroscopy techniques. 1989 Biochem. Pharmacol. pmid:2910295
Nambi P et al. Induction of functional beta-adrenergic receptors in rat aortic smooth muscle cells by sodium butyrate. 1986 Biochem. Pharmacol. pmid:3022740
Krahenbuhl S and Brass EP Inhibition of hepatic propionyl-CoA synthetase activity by organic acids. Reversal of propionate inhibition of pyruvate metabolism. 1991 Mar 15-Apr 1 Biochem. Pharmacol. pmid:2009071
Muramatsu M et al. Enhancement of affinity to receptors in the esterified glucocorticoid, hydrocortisone 17-butyrate 21-propionate (HBP), in the rat liver. 1986 Biochem. Pharmacol. pmid:3718538
Sumegi B et al. Is there tight channelling in the tricarboxylic acid cycle metabolon? 1991 Biochem. Soc. Trans. pmid:1794455
Busse SC and Jue T Two-dimensional NMR characterization of the deoxymyoglobin heme pocket. 1994 Biochemistry pmid:8086410
Chen Z et al. Phe393 mutants of cytochrome P450 BM3 with modified heme redox potentials have altered heme vinyl and propionate conformations. 2004 Biochemistry pmid:14967021
Sherry AD et al. Orientation-conserved transfer of symmetric Krebs cycle intermediates in mammalian tissue. 1994 Biochemistry pmid:7910760
LeMagueres P et al. Crystal structure at 1.45 A resolution of alanine racemase from a pathogenic bacterium, Pseudomonas aeruginosa, contains both internal and external aldimine forms. 2003 Biochemistry pmid:14674749
Ibrahim M et al. Soluble guanylate cyclase is activated differently by excess NO and by YC-1: resonance Raman spectroscopic evidence. 2010 Biochemistry pmid:20459051
Rwere F et al. Resonance Raman interrogation of the consequences of heme rotational disorder in myoglobin and its ligated derivatives. 2008 Biochemistry pmid:18986170
Louie GV et al. Role of phenylalanine-82 in yeast iso-1-cytochrome c and remote conformational changes induced by a serine residue at this position. 1988 Biochemistry pmid:2849996
Zhao D et al. Structure and stability effects of the mutation of glycine 34 to serine in Rhodobacter capsulatus cytochrome c(2). 2000 Biochemistry pmid:10747794
Manna SK and Mazumdar S Role of threonine 101 on the stability of the heme active site of cytochrome P450cam: multiwavelength circular dichroism studies. 2006 Biochemistry pmid:17042489
Seibold SA et al. Water chain formation and possible proton pumping routes in Rhodobacter sphaeroides cytochrome c oxidase: a molecular dynamics comparison of the wild type and R481K mutant. 2005 Biochemistry pmid:16060656
Ibrahim M et al. Probing soluble guanylate cyclase activation by CO and YC-1 using resonance Raman spectroscopy. 2010 Biochemistry pmid:20353168
Haller T et al. Discovering new enzymes and metabolic pathways: conversion of succinate to propionate by Escherichia coli. 2000 Biochemistry pmid:10769117
Meharenna YT et al. Engineering ascorbate peroxidase activity into cytochrome c peroxidase. 2008 Biochemistry pmid:18771292
Timkovich R et al. 1H NMR spectroscopy of Paracoccus denitrificans cytochrome c-550. 1984 Biochemistry pmid:6087896
Tran R et al. Determinants of the heme-CO vibrational modes in the H-NOX family. 2011 Biochemistry pmid:21714509
Nagai M et al. Heme structure of hemoglobin M Iwate [alpha 87(F8)His-->Tyr]: a UV and visible resonance Raman study. 2000 Biochemistry pmid:11052661
Yang X et al. Cholesterol metabolism increases the metabolic pool of propionate in Mycobacterium tuberculosis. 2009 Biochemistry pmid:19364125
Santucci R et al. Anion size modulates the structure of the A state of cytochrome c. 2000 Biochemistry pmid:11027143
Yoshimura H et al. Specific hydrogen-bonding networks responsible for selective O2 sensing of the oxygen sensor protein HemAT from Bacillus subtilis. 2006 Biochemistry pmid:16819829
Hellwig P et al. Electrochemical, FTIR, and UV/VIS spectroscopic properties of the ba(3) oxidase from Thermus thermophilus. 1999 Biochemistry pmid:10423243
Sakurai M et al. Glutamate 325 is a general acid-base catalyst in the reaction catalyzed by fructose-2,6-bisphosphatase. 2000 Biochemistry pmid:11123954
Nakamura S et al. Structure of cytochrome c552 from a moderate thermophilic bacterium, Hydrogenophilus thermoluteolus: comparative study on the thermostability of cytochrome c. 2006 Biochemistry pmid:16681384
Mauk MR et al. Electrostatic analysis of the interaction of cytochrome c with native and dimethyl ester heme substituted cytochrome b5. 1986 Biochemistry pmid:3026446
Chao YY et al. 1H NMR and ESR studies of oxidized cytochrome c551 from Pseudomonas aeruginosa. 1979 Biochemistry pmid:33701
Cutler RL et al. Role of arginine-38 in regulation of the cytochrome c oxidation-reduction equilibrium. 1989 Biochemistry pmid:2545252
Chen Z et al. Resonance Raman investigation of the interaction of thromboxane synthase with substrate analogues. 2003 Biochemistry pmid:12614148
Peyton DH et al. Proton nuclear magnetic resonance study of the molecular and electronic structure of the heme cavity in Aplysia cyanometmyoglobin. 1989 Biochemistry pmid:2548594
Liu GY et al. Ionic strength dependence of cytochrome c structure and Trp-59 H/D exchange from ultraviolet resonance Raman spectroscopy. 1989 Biochemistry pmid:2548599
Shokhireva TKh et al. Assignment of heme resonances and determination of the electronic structures of high- and low-spin nitrophorin 2 by 1H and 13C NMR spectroscopy: an explanation of the order of heme methyl resonances in high-spin ferriheme proteins. 2003 Biochemistry pmid:12534280
Hector ML and Fall RR Multiple acyl-coenzyme A carboxylases in Pseudomonas citronellolis. 1976 Biochemistry pmid:8091
Omura S et al. Studies on the biosynthesis of 16-membered macrolide antibiotics using carbon-13 nuclear magnetic resonance spectroscopy. 1977 Biochemistry pmid:18162
Wilson DF and Forman NG Mitochondrial transmembrane pH and electrical gradients: evaluation of their energy relationships with respiratory rate and adenosine 5'-triphosphate synthesis. 1982 Biochemistry pmid:7074098
Efimov I et al. Structure and reaction mechanism in the heme dioxygenases. 2011 Biochemistry pmid:21361337
Stellwagen E and Babul J Stabilization of the globular structure of ferricytochrome c by chloride in acidic solvents. 1975 Biochemistry pmid:41
Mileni M et al. Probing heme propionate involvement in transmembrane proton transfer coupled to electron transfer in dihemic quinol:fumarate reductase by 13C-labeling and FTIR difference spectroscopy. 2005 Biochemistry pmid:16342962
Mascaretti OA et al. Biosynthesis of the macrolide antibiotic chlorothricin. 1981 Biochemistry pmid:7011379
Barrows TP and Poulos TL Role of electrostatics and salt bridges in stabilizing the compound I radical in ascorbate peroxidase. 2005 Biochemistry pmid:16245922
Dayem LC et al. Metabolic engineering of a methylmalonyl-CoA mutase-epimerase pathway for complex polyketide biosynthesis in Escherichia coli. 2002 Biochemistry pmid:11955068
Brigé A et al. The 1.25 A resolution structure of the diheme NapB subunit of soluble nitrate reductase reveals a novel cytochrome c fold with a stacked heme arrangement. 2002 Biochemistry pmid:11939777
Behr J et al. Functional properties of the heme propionates in cytochrome c oxidase from Paracoccus denitrificans. Evidence from FTIR difference spectroscopy and site-directed mutagenesis. 2000 Biochemistry pmid:10684616
Gaudin CF et al. Unique heme-iron coordination by the hemoglobin receptor IsdB of Staphylococcus aureus. 2011 Biochemistry pmid:21574663
Horswill AR and Escalante-Semerena JC Characterization of the propionyl-CoA synthetase (PrpE) enzyme of Salmonella enterica: residue Lys592 is required for propionyl-AMP synthesis. 2002 Biochemistry pmid:11841231
Delker SL et al. Role of zinc in isoform-selective inhibitor binding to neuronal nitric oxide synthase . 2010 Biochemistry pmid:21138269
Bunik VI et al. Phosphonate analogues of alpha-ketoglutarate inhibit the activity of the alpha-ketoglutarate dehydrogenase complex isolated from brain and in cultured cells. 2005 Biochemistry pmid:16060664
Raman CS et al. Crystal structure of nitric oxide synthase bound to nitro indazole reveals a novel inactivation mechanism. 2001 Biochemistry pmid:11695891
Stayton PS et al. Putidaredoxin competitively inhibits cytochrome b5-cytochrome P-450cam association: a proposed molecular model for a cytochrome P-450cam electron-transfer complex. 1989 Biochemistry pmid:2690937
Sundaramoorthy M et al. High-resolution crystal structure of manganese peroxidase: substrate and inhibitor complexes. 2005 Biochemistry pmid:15850380
Harada K et al. Structure and ligand binding properties of myoglobins reconstituted with monodepropionated heme: functional role of each heme propionate side chain. 2007 Biochemistry pmid:17636874
Evans HJ and Wood HG Purification and properties of pyruvate phosphate dikinase from propionic acid bacteria. 1971 Biochemistry pmid:5544662
Key J and Moffat K Crystal structures of deoxy and CO-bound bjFixLH reveal details of ligand recognition and signaling. 2005 Biochemistry pmid:15779889
Ahmed AH et al. Mechanisms of antagonism of the GluR2 AMPA receptor: structure and dynamics of the complex of two willardiine antagonists with the glutamate binding domain. 2009 Biochemistry pmid:19284741
Sherman MM and Hutchinson CR Biosynthesis of lasalocid A: biochemical mechanism for assembly of the carbon framework. 1987 Biochemistry pmid:3828316
Singh R et al. Unprecedented peroxidase-like activity of Rhodnius prolixus nitrophorin 2: identification of the [FeIV=O Por•]+ and [FeIV=O Por](Tyr38•) intermediates and their role(s) in substrate oxidation. 2010 Biochemistry pmid:20726527
Zhang H et al. Characterization of the high-spin heme x in the cytochrome b6f complex of oxygenic photosynthesis. 2004 Biochemistry pmid:15610027
Grimshaw CE et al. Use of isotope effects and pH studies to determine the chemical mechanism of Bacillus subtilis L-alanine dehydrogenase. 1981 Biochemistry pmid:6794612
Schrimsher JL and Taylor KB Octopine dehydrogenase from Pecten maximus: steady-state mechanism. 1984 Biochemistry pmid:6722094
Mendoza MF et al. Human NAD(P)H:quinone oxidoreductase type I (hNQO1) activation of quinone propionic acid trigger groups. 2012 Biochemistry pmid:22989153