| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cecal Diseases | D002429 | 3 associated lipids |
| Cattle Diseases | D002418 | 24 associated lipids |
| Candidiasis, Oral | D002180 | 11 associated lipids |
| Campylobacter Infections | D002169 | 13 associated lipids |
| Bursitis | D002062 | 3 associated lipids |
| Burkitt Lymphoma | D002051 | 15 associated lipids |
| Brain Diseases | D001927 | 27 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Blind Loop Syndrome | D001765 | 3 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Asthma | D001249 | 52 associated lipids |
| Arthritis, Juvenile | D001171 | 8 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Anus Diseases | D001004 | 3 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Angioedema | D000799 | 6 associated lipids |
| Anemia, Sickle Cell | D000755 | 34 associated lipids |
| Amino Acid Metabolism, Inborn Errors | D000592 | 16 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
propionic acid
propionic acid is a lipid of Fatty Acyls (FA) class. Propionic acid is associated with abnormalities such as Epilepsy, Infection, Tuberculosis, Alkalosis and Ischemia. The involved functions are known as Uptake, Biosynthetic Pathways, Methylation, Protein Overexpression and Biochemical Pathway. Propionic acid often locates in Body tissue, Cytoplasmic matrix, Membrane, Protoplasm and Extracellular. The associated genes with propionic acid are TRIO gene, TRRAP gene, SLC5A8 gene, SLC33A1 gene and Homologous Gene. The related lipids are Fatty Acids, Propionate, butyrate, Valerates and mycocerosic acid.
Cross Reference
Introduction
To understand associated biological information of propionic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with propionic acid?
propionic acid is suspected in Propionic acidemia, Ischemia, Infection, Ulcerative Colitis, Alkalosis, Methylmalonic acidemia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with propionic acid
PubChem Associated disorders and diseases
What pathways are associated with propionic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with propionic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with propionic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with propionic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with propionic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with propionic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with propionic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Murphy EJ et al. | Engineering the substrate specificity and reactivity of a heme protein: creation of an ascorbate binding site in cytochrome c peroxidase. | 2008 | Biochemistry | pmid:19061385 |
| Chen Z et al. | Phe393 mutants of cytochrome P450 BM3 with modified heme redox potentials have altered heme vinyl and propionate conformations. | 2004 | Biochemistry | pmid:14967021 |
| Rwere F et al. | Resonance Raman interrogation of the consequences of heme rotational disorder in myoglobin and its ligated derivatives. | 2008 | Biochemistry | pmid:18986170 |
| Manna SK and Mazumdar S | Role of threonine 101 on the stability of the heme active site of cytochrome P450cam: multiwavelength circular dichroism studies. | 2006 | Biochemistry | pmid:17042489 |
| Ibrahim M et al. | Probing soluble guanylate cyclase activation by CO and YC-1 using resonance Raman spectroscopy. | 2010 | Biochemistry | pmid:20353168 |
| Haller T et al. | Discovering new enzymes and metabolic pathways: conversion of succinate to propionate by Escherichia coli. | 2000 | Biochemistry | pmid:10769117 |
| Timkovich R et al. | 1H NMR spectroscopy of Paracoccus denitrificans cytochrome c-550. | 1984 | Biochemistry | pmid:6087896 |
| Tran R et al. | Determinants of the heme-CO vibrational modes in the H-NOX family. | 2011 | Biochemistry | pmid:21714509 |
| Yang X et al. | Cholesterol metabolism increases the metabolic pool of propionate in Mycobacterium tuberculosis. | 2009 | Biochemistry | pmid:19364125 |
| Hellwig P et al. | Electrochemical, FTIR, and UV/VIS spectroscopic properties of the ba(3) oxidase from Thermus thermophilus. | 1999 | Biochemistry | pmid:10423243 |
| Sakurai M et al. | Glutamate 325 is a general acid-base catalyst in the reaction catalyzed by fructose-2,6-bisphosphatase. | 2000 | Biochemistry | pmid:11123954 |
| Mauk MR et al. | Electrostatic analysis of the interaction of cytochrome c with native and dimethyl ester heme substituted cytochrome b5. | 1986 | Biochemistry | pmid:3026446 |
| Chao YY et al. | 1H NMR and ESR studies of oxidized cytochrome c551 from Pseudomonas aeruginosa. | 1979 | Biochemistry | pmid:33701 |
| Timkovich R and Cork MS | Proton NMR spectroscopy of cytochrome c-554 from Alcaligenes faecalis. | 1984 | Biochemistry | pmid:6324856 |
| Chen Z et al. | Resonance Raman investigation of the interaction of thromboxane synthase with substrate analogues. | 2003 | Biochemistry | pmid:12614148 |
| Wilson DF and Forman NG | Mitochondrial transmembrane pH and electrical gradients: evaluation of their energy relationships with respiratory rate and adenosine 5'-triphosphate synthesis. | 1982 | Biochemistry | pmid:7074098 |
| Stellwagen E and Babul J | Stabilization of the globular structure of ferricytochrome c by chloride in acidic solvents. | 1975 | Biochemistry | pmid:41 |
| Mimura K et al. | Isolation of stable (alphabeta)4-Tetraprotomer from Na+/K+-ATPase solubilized in the presence of short-chain fatty acids. | 2008 | Biochemistry | pmid:18465843 |
| Lee HJ et al. | Properties of Arg481 mutants of the aa3-type cytochrome c oxidase from Rhodobacter sphaeroides suggest that neither R481 nor the nearby D-propionate of heme a3 is likely to be the proton loading site of the proton pump. | 2009 | Biochemistry | pmid:19575527 |
| Dayem LC et al. | Metabolic engineering of a methylmalonyl-CoA mutase-epimerase pathway for complex polyketide biosynthesis in Escherichia coli. | 2002 | Biochemistry | pmid:11955068 |
| Brigé A et al. | The 1.25 A resolution structure of the diheme NapB subunit of soluble nitrate reductase reveals a novel cytochrome c fold with a stacked heme arrangement. | 2002 | Biochemistry | pmid:11939777 |
| Horswill AR and Escalante-Semerena JC | Characterization of the propionyl-CoA synthetase (PrpE) enzyme of Salmonella enterica: residue Lys592 is required for propionyl-AMP synthesis. | 2002 | Biochemistry | pmid:11841231 |
| Bunik VI et al. | Phosphonate analogues of alpha-ketoglutarate inhibit the activity of the alpha-ketoglutarate dehydrogenase complex isolated from brain and in cultured cells. | 2005 | Biochemistry | pmid:16060664 |
| Brändén G et al. | The protonation state of a heme propionate controls electron transfer in cytochrome c oxidase. | 2005 | Biochemistry | pmid:16060655 |
| Mills DA et al. | An arginine to lysine mutation in the vicinity of the heme propionates affects the redox potentials of the hemes and associated electron and proton transfer in cytochrome c oxidase. | 2005 | Biochemistry | pmid:16060654 |
| Sundaramoorthy M et al. | High-resolution crystal structure of manganese peroxidase: substrate and inhibitor complexes. | 2005 | Biochemistry | pmid:15850380 |
| Evans HJ and Wood HG | Purification and properties of pyruvate phosphate dikinase from propionic acid bacteria. | 1971 | Biochemistry | pmid:5544662 |
| Ahmed AH et al. | Mechanisms of antagonism of the GluR2 AMPA receptor: structure and dynamics of the complex of two willardiine antagonists with the glutamate binding domain. | 2009 | Biochemistry | pmid:19284741 |
| Schrimsher JL and Taylor KB | Octopine dehydrogenase from Pecten maximus: steady-state mechanism. | 1984 | Biochemistry | pmid:6722094 |
| Sivuk VF et al. | Purification and characteristics of functional properties of soluble nucleoside triphosphatase (apyrase) from bovine brain. | 2008 | Biochemistry Mosc. | pmid:18976223 |
| Kondakova AN et al. | New structures of the O-specific polysaccharides of Proteus. 3. Polysaccharides containing non-carbohydrate organic acids. | 2003 | Biochemistry Mosc. | pmid:12765528 |
| Enser U and Heber U | Metabolic regulation by pH gradients. Inhibition of photosynthesis by indirect proton transfer across the chloroplast envelope. | 1980 | Biochim. Biophys. Acta | pmid:6251871 |
| Yount EA and Harris RA | Studies on the inhibition of gluconeogenesis by oxalate. | 1980 | Biochim. Biophys. Acta | pmid:6778509 |
| Koutsoupakis C et al. | Time-resolved step-scan Fourier transform infrared investigation of heme-copper oxidases: implications for O2 input and H2O/H+ output channels. | 2004 | Biochim. Biophys. Acta | pmid:15100050 |
| Sokolov S et al. | Ysp2 mediates death of yeast induced by amiodarone or intracellular acidification. | Biochim. Biophys. Acta | pmid:16962064 | |
| Taylor A et al. | The effects of propionate on sodium transport by the toad bladder. Evidence for a metabolic mode of action. | 1973 | Biochim. Biophys. Acta | pmid:4198138 |
| Riistama S et al. | Interaction between the formyl group of heme a and arginine 54 in cytochrome aa(3) from Paracoccus denitrificans. | 2000 | Biochim. Biophys. Acta | pmid:10611451 |
| Roos P et al. | Isolation of five active thyrotropin components from human pituitary gland. | 1975 | Biochim. Biophys. Acta | pmid:1125234 |
| Tomaro ML et al. | The oxidation of hemins by microsomal heme oxygenase. Structural requirements for the retention of substrate activity. | 1984 | Biochim. Biophys. Acta | pmid:6549143 |
| Alonso WR and Nelson DA | A novel yeast histone deacetylase: partial characterization and development of an activity assay. | 1986 | Biochim. Biophys. Acta | pmid:3513841 |
| Ku EC and Wasvary JM | Inhibition of prostaglandin synthase by pirprofen. Studies with sheep seminal vesicle enzyme. | 1975 | Biochim. Biophys. Acta | pmid:804924 |
| Martin JF and Mcdaniel LE | Specific inhibition of candicidin biosynthesis by the lipogenic inhibitor cerulenin. | 1975 | Biochim. Biophys. Acta | pmid:811262 |
| Yamamoto Y et al. | 1H-NMR study of dynamics and thermodynamics of Cl- binding to ferric hemoglobin of a midge larva (Tokunagayusurika akamusi). | 2003 | Biochim. Biophys. Acta | pmid:14644049 |
| Sundqvist KE et al. | Effect of acetate and octanoate on tricarboxylic acid cycle metabolite disposal during propionate oxidation in the perfused rat heart. | 1984 | Biochim. Biophys. Acta | pmid:6487652 |
| Fonteriz RI et al. | The role of intracellular acidification in calcium mobilization in human neutrophils. | 1991 | Biochim. Biophys. Acta | pmid:2049405 |
| Moore GR et al. | pH dependence of the redox potential of Pseudomonas aeruginosa cytochrome c-551. | 1980 | Biochim. Biophys. Acta | pmid:6245686 |
| Wall MJ et al. | The effect of short chain fatty acids on transmural electrical potential across rat small intestine in vivo. | 1976 | Biochim. Biophys. Acta | pmid:179592 |
| Yoshikawa S et al. | Proton pumping mechanism of bovine heart cytochrome c oxidase. | Biochim. Biophys. Acta | pmid:16904626 | |
| Keller RM and Wüthrich K | Assignment of the heme c resonances in the 360 MHz H NMR spectra of cytochrome c. | 1978 | Biochim. Biophys. Acta | pmid:205265 |
| Loureiro SO et al. | Propionic and methylmalonic acids increase cAMP levels in slices of cerebral cortex of young rats via adrenergic and glutamatergic mechanisms. | 2005 | Biochim. Biophys. Acta | pmid:15949715 |
| Dyer C et al. | Cyanide reactivity of cytochrome c derivatives. | 1979 | Biochim. Biophys. Acta | pmid:231457 |
| Yu MA et al. | Radical formation in cytochrome c oxidase. | 2011 | Biochim. Biophys. Acta | pmid:21718686 |
| Hess JJ et al. | On the effects of propionate and other short-chain fatty acids on sodium transport by the toad bladder. | 1975 | Biochim. Biophys. Acta | pmid:236789 |
| Henly DC and Berry MN | Relationship between the stimulation of citric acid cycle oxidation and the stimulation of fatty acid esterification and inhibition of ketogenesis by lactate in isolated rat hepatocytes. | 1991 | Biochim. Biophys. Acta | pmid:1828700 |
| Grinstein S et al. | Chemical modification of the Na+/H+ exchanger of thymic lymphocytes. Inhibition by N-ethylmaleimide. | 1985 | Biochim. Biophys. Acta | pmid:2981544 |
| de Silva DG and Sykes AG | Interpretation of effects of pH on rate constants for the oxidation of three ferrocytochromes c-551 with [Fe(CN)6]3- and [Co(phen)3]3+, and assignment of pKa values. | 1988 | Biochim. Biophys. Acta | pmid:2827782 |
| Lancaster CR et al. | Recent progress on obtaining theoretical and experimental support for the "E-pathway hypothesis" of coupled transmembrane electron and proton transfer in dihaem-containing quinol:fumarate reductase. | 2006 | Biochim. Biophys. Acta | pmid:16790236 |
| Knight LC and Welch MJ | Sites of direct and indirect halogenation of albumin. | 1978 | Biochim. Biophys. Acta | pmid:27226 |
| Wikström M et al. | Water-gated mechanism of proton translocation by cytochrome c oxidase. | 2003 | Biochim. Biophys. Acta | pmid:12765763 |
| Pettigrew GW et al. | Redox potentials of the photosynthetic bacterial cytochromes c2 and the structural bases for variability. | 1978 | Biochim. Biophys. Acta | pmid:28760 |
| Zheng X et al. | Computer simulation of water in cytochrome c oxidase. | 2003 | Biochim. Biophys. Acta | pmid:12615353 |
| Wasternack C et al. | Pyrimidine-degrading enzymes. Purification and properties of beta-ureidopropionase of Euglena gracilis. | 1979 | Biochim. Biophys. Acta | pmid:115499 |
| Trewhella J and Wright PE | 1H-NMR studies of ferric soybean leghemoglobin: assignment of hyperfine shifted resonances of complexes with cyanide, nicotinate, pyridine and azide. | 1980 | Biochim. Biophys. Acta | pmid:7192162 |
| Keller R et al. | Contact-shifted resonances in the 1H NMR spectra of cytochrome b5. Resonance identification and spin density distribution in the heme group. | 1976 | Biochim. Biophys. Acta | pmid:5127 |
| Baskin LS and Yang CS | Cross-linking studies of the protein topography of rat liver microsomes. | 1982 | Biochim. Biophys. Acta | pmid:7055568 |
| Rafidinarivo E et al. | Branched fatty acids from Mycobacterium aurum. | 1982 | Biochim. Biophys. Acta | pmid:7093295 |
| Hayashi S et al. | Steady-state kinetics and spectral properties of Corynebacterium sarcosine oxidase. | 1983 | Biochim. Biophys. Acta | pmid:6188492 |
| Rotsaert FA et al. | Mutations in cytochrome b that affect kinetics of the electron transfer reactions at center N in the yeast cytochrome bc1 complex. | 2008 | Biochim. Biophys. Acta | pmid:18328328 |
| Adir N et al. | Refined structure of c-phycocyanin from the cyanobacterium Synechococcus vulcanus at 1.6 A: insights into the role of solvent molecules in thermal stability and co-factor structure. | 2002 | Biochim. Biophys. Acta | pmid:12460674 |
| HASSALL H and GREENBERG DM | The oxidation of 4(5)-imidazolone-5(4)-propionic acid to hydantoin-5-propionic acid by xanthine oxidase. | 1963 | Biochim. Biophys. Acta | pmid:13960896 |
| Peuhkurinen KJ | Accumulation and disposal of tricarboxylic acid cycle intermediates during propionate oxidation in the isolated perfused rat heart. | 1982 | Biochim. Biophys. Acta | pmid:7138913 |
| Fiedor L et al. | Understanding chlorophylls: central magnesium ion and phytyl as structural determinants. | 2008 | Biochim. Biophys. Acta | pmid:18848915 |
| Bear CE et al. | Intracellular pH influences the resting membrane potential of isolated rat hepatocytes. | 1988 | Biochim. Biophys. Acta | pmid:3179283 |
| Ticku MK and Olsen RW | gamma-Aminobutyric acid-stimulated chloride permeability in crayfish muscle. | 1977 | Biochim. Biophys. Acta | pmid:836825 |
| Xu J and Voth GA | Redox-coupled proton pumping in cytochrome c oxidase: further insights from computer simulation. | 2008 | Biochim. Biophys. Acta | pmid:18155154 |
| TOMLINSON N and MACLEOD RA | The oxidation of propionic acid by a marine bacterium. | 1955 | Biochim. Biophys. Acta | pmid:13304045 |
| Itoh N et al. | Cloning and biochemical characterization of Co(2+)-activated bromoperoxidase-esterase (perhydrolase) from Pseudomonas putida IF-3 strain. | 2001 | Biochim. Biophys. Acta | pmid:11342031 |
| WOOD HG and LEAVER FW | CO2 turnover in the fermentation of 3,4,5 and 6 carbon compounds by the propionic acid bacteria. | Biochim. Biophys. Acta | pmid:13115430 | |
| Kay WW | Genetic control of the metabolism of propionate by Escherichia coli K12. | 1972 | Biochim. Biophys. Acta | pmid:4554901 |
| Hokland BM and Bremer J | Metabolism and excretion of carnitine and acylcarnitines in the perfused rat kidney. | 1986 | Biochim. Biophys. Acta | pmid:3697382 |
| Egawa T et al. | Critical structural role of R481 in cytochrome c oxidase from Rhodobacter sphaeroides. | 2009 | Biochim. Biophys. Acta | pmid:19463779 |
| Hiltunen JK and Davis EJ | The disposition of citric acid cycle intermediates by isolated rat heart mitochondria. | 1981 | Biochim. Biophys. Acta | pmid:7306575 |
| Jørgensen KE and Sheikh MI | Characteristics of uptake of short chain fatty acids by luminal membrane vesicles from rabbit kidney. | 1986 | Biochim. Biophys. Acta | pmid:3741867 |
| Brass EP | Effect of alpha-ketobutyrate on palmitic acid and pyruvate metabolism in isolated rat hepatocytes. | 1986 | Biochim. Biophys. Acta | pmid:3741887 |
| Richard E et al. | Genetic heterogeneity in propionic acidemia patients with alpha-subunit defects. Identification of five novel mutations, one of them causing instability of the protein. | 1999 | Biochim. Biophys. Acta | pmid:10101253 |
| Yoshikawa S et al. | Structural studies on bovine heart cytochrome c oxidase. | 2012 | Biochim. Biophys. Acta | pmid:22236806 |
| Emmanuel B | The relative contribution of propionate, and long-chain even-numbered fatty acids to the production of long-chain odd-numbered fatty acids in rumen bacteria. | 1978 | Biochim. Biophys. Acta | pmid:564207 |
| Desire B and Saint-Andre S | [Accelerating effect of heterocyclic quaternary ammonium salts on neutral ester hydrolysis by acetylcholinesterase and butyrylcholinesterase (author's transl)]. | 1981 | Biochim. Biophys. Acta | pmid:7260096 |
| Gens JS et al. | Different ionic conditions prompt NHE2 and NHE3 translocation to the plasma membrane. | 2007 | Biochim. Biophys. Acta | pmid:17303069 |
| Ellfolk N and Perttilä U | Heme sulfuric anhydrides as soybean leghemoglobin structure probes. | 1978 | Biochim. Biophys. Acta | pmid:656461 |
| Scaife JR and Tichivangana JZ | Short chain acyl-CoA synthetases in ovine rumen epithelium. | 1980 | Biochim. Biophys. Acta | pmid:7407228 |
| Kaila VR et al. | The identity of the transient proton loading site of the proton-pumping mechanism of cytochrome c oxidase. | 2011 | Biochim. Biophys. Acta | pmid:20831859 |
| Honig GR et al. | Hemoglobin F Lódź (G gamma I 44 Ser replaced by Arg). A newly identified variant from an American infant of Polish descent. | 1982 | Biochim. Biophys. Acta | pmid:6814491 |
| Benavides J et al. | Glycine transport in rat brain and liver mitochondria. | 1980 | Biochim. Biophys. Acta | pmid:7388024 |
| Jacobson G et al. | Human pituitary thyrotropin. Isolation of alpha and beta subunits by hydrophobic interaction chromatography. | 1978 | Biochim. Biophys. Acta | pmid:708778 |
| Hellwig P et al. | Spectroscopic study on the communication between a heme a3 propionate, Asp399 and the binuclear center of cytochrome c oxidase from Paracoccus denitrificans. | 2008 | Biochim. Biophys. Acta | pmid:18078804 |
| Kaur S et al. | Dimorphism-associated changes in intracellular pH of Candida albicans. | 1988 | Biochim. Biophys. Acta | pmid:2904280 |
| Ford SH | Amidation of, and (R)-1-amino-2-propanol attachment to, the corrin ring during vitamin B-12 biosynthesis by Clostridium tetanomorphum extracts. | 1985 | Biochim. Biophys. Acta | pmid:4027268 |
| Trotter PJ and Storch J | 3-[p-(6-phenyl)-1,3,5-hexatrienyl]phenylpropionic acid (PA-DPH): characterization as a fluorescent membrane probe and binding to fatty acid binding proteins. | 1989 | Biochim. Biophys. Acta | pmid:2742883 |
| Al-Lahham SH et al. | Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms. | 2010 | Biochim. Biophys. Acta | pmid:20691280 |