propionic acid
propionic acid is a lipid of Fatty Acyls (FA) class. Propionic acid is associated with abnormalities such as Epilepsy, Infection, Tuberculosis, Alkalosis and Ischemia. The involved functions are known as Uptake, Biosynthetic Pathways, Methylation, Protein Overexpression and Biochemical Pathway. Propionic acid often locates in Body tissue, Cytoplasmic matrix, Membrane, Protoplasm and Extracellular. The associated genes with propionic acid are TRIO gene, TRRAP gene, SLC5A8 gene, SLC33A1 gene and Homologous Gene. The related lipids are Fatty Acids, Propionate, butyrate, Valerates and mycocerosic acid.
Cross Reference
Introduction
To understand associated biological information of propionic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with propionic acid?
propionic acid is suspected in Propionic acidemia, Ischemia, Infection, Ulcerative Colitis, Alkalosis, Methylmalonic acidemia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with propionic acid
PubChem Associated disorders and diseases
What pathways are associated with propionic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with propionic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with propionic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with propionic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with propionic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with propionic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with propionic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Stankovics J and Ledley FD | Cloning of functional alpha propionyl CoA carboxylase and correction of enzyme deficiency in pccA fibroblasts. | 1993 | Am. J. Hum. Genet. | pmid:8434582 |
| Pirson Y and van Ypersele de Strihou C | Renal side effects of nonsteroidal antiinflammatory drugs: clinical relevance. | 1986 | Am. J. Kidney Dis. | pmid:3538858 |
| Van Hove JL et al. | Cobalamin disorder Cbl-C presenting with late-onset thrombotic microangiopathy. | 2002 | Am. J. Med. Genet. | pmid:12210350 |
| Van Calcar SC et al. | Case reports of successful pregnancy in women with maple syrup urine disease and propionic acidemia. | 1992 | Am. J. Med. Genet. | pmid:1481826 |
| Werlin SL | E. coli sepsis as a presenting sign in neonatal propionic acidemia. | 1993 | Am. J. Med. Genet. | pmid:8357022 |
| Shih VE et al. | Defective lysosomal release of vitamin B12 (cb1F): a hereditary cobalamin metabolic disorder associated with sudden death. | 1989 | Am. J. Med. Genet. | pmid:2596518 |
| Gilmore A et al. | Hyperamylasemia/hyperlipasemia in a child with propionic acidemia. | 2008 | Am. J. Med. Genet. A | pmid:19006211 |
| Morrow G et al. | Propionate metabolism in fetal livers of 15 to 19 weeks' gestation. | 1975 | Am. J. Obstet. Gynecol. | pmid:1115133 |
| ALTER RL et al. | The treatment of mycotic vulvovaginitis with propionate vaginal jelly. | 1947 | Am. J. Obstet. Gynecol. | pmid:20286636 |
| Williams ZR et al. | Late onset optic neuropathy in methylmalonic and propionic acidemia. | 2009 | Am. J. Ophthalmol. | pmid:19243738 |
| Clark DA et al. | Contribution of oxygen-derived free radicals to experimental necrotizing enterocolitis. | 1988 | Am. J. Pathol. | pmid:3348358 |
| Graber ML et al. | Fluorescence identifies an alkaline cell in turtle urinary bladder. | 1986 | Am. J. Physiol. | pmid:3942220 |
| Conn AR and Steele RD | Transport of alpha-keto analogues of amino acids across blood-brain barrier in rats. | 1982 | Am. J. Physiol. | pmid:6751096 |
| Nutting CW et al. | Vasorelaxant effects of short chain fatty acid salts in rat caudal artery. | 1991 | Am. J. Physiol. | pmid:1877681 |
| de Hemptinne A et al. | Influence of organic acids on intracellular pH. | 1983 | Am. J. Physiol. | pmid:6614155 |
| Conn AR et al. | Characterization of alpha-keto acid transport across blood-brain barrier in rats. | 1983 | Am. J. Physiol. | pmid:6614164 |
| Parfenova H and Leffler CW | Effects of hypercapnia on prostanoid and cAMP production by cerebral microvascular cell cultures. | 1996 | Am. J. Physiol. | pmid:8967453 |
| Sellin JH and De Soignie R | Ionic regulation of Na absorption in proximal colon: cation inhibition of electroneutral Na absorption. | 1987 | Am. J. Physiol. | pmid:3812678 |
| Mariadason JM et al. | Effect of short-chain fatty acids on paracellular permeability in Caco-2 intestinal epithelium model. | 1997 | Am. J. Physiol. | pmid:9142899 |
| Yamaji Y et al. | Intracellular acidosis activates c-Src. | 1997 | Am. J. Physiol. | pmid:9124524 |