propionic acid is a lipid of Fatty Acyls (FA) class. Propionic acid is associated with abnormalities such as Epilepsy, Infection, Tuberculosis, Alkalosis and Ischemia. The involved functions are known as Uptake, Biosynthetic Pathways, Methylation, Protein Overexpression and Biochemical Pathway. Propionic acid often locates in Body tissue, Cytoplasmic matrix, Membrane, Protoplasm and Extracellular. The associated genes with propionic acid are TRIO gene, TRRAP gene, SLC5A8 gene, SLC33A1 gene and Homologous Gene. The related lipids are Fatty Acids, Propionate, butyrate, Valerates and mycocerosic acid.
To understand associated biological information of propionic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
propionic acid is suspected in Propionic acidemia, Ischemia, Infection, Ulcerative Colitis, Alkalosis, Methylmalonic acidemia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with propionic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Ozaki Y et al. | Modification of Na+/H+ exchanger in human platelets by 1,2-dioctanoylglycerol, a protein kinase C activator. | 1990 | Thromb. Haemost. | pmid:2177231 |
Hsu WC et al. | [Propionic acidemia: report of a case that is successfully managed by peritoneal dialysis and sodium benzoate therapy]. | 1990 | Zhonghua Yi Xue Za Zhi (Taipei) | pmid:2178070 |
Genet R and Lederer F | The carbanion of nitroethane is an inhibitor of, and not a substrate for, flavocytochrome b2 [L-(+)-lactate dehydrogenase]. | 1990 | Biochem. J. | pmid:2178603 |
Thompson GN et al. | Sources of propionate in inborn errors of propionate metabolism. | 1990 | Metab. Clin. Exp. | pmid:2233273 |
Weder AB et al. | Platelet volume responses to cytoplasmic acidification in essential hypertension. | 1990 | J. Hypertens. | pmid:1962803 |
Ramsay BA et al. | Production of poly-(beta-hydroxybutyric-co-beta-hydroxyvaleric) acids. | 1990 | Appl. Environ. Microbiol. | pmid:2117877 |
Rolland MO et al. | Early prenatal diagnosis of propionic acidaemia with simultaneous sampling of chorionic villus and amniotic fluid. | 1990 | J. Inherit. Metab. Dis. | pmid:2122098 |
Thompson GN et al. | A simple isotopic technique for assessing vitamin responsiveness in vivo in propionic acidaemia. | 1990 | J. Inherit. Metab. Dis. | pmid:2122099 |
Vanderstichele H et al. | Regulation of the pituitary 5 alpha-reductase activity by gonadotropin releasing hormone and testosterone in the adult male rat. | 1990 | J. Steroid Biochem. | pmid:2141376 |
Cherrington CA et al. | Short-chain organic acids at ph 5.0 kill Escherichia coli and Salmonella spp. without causing membrane perturbation. | 1991 | J. Appl. Bacteriol. | pmid:1902205 |
Nakai A et al. | Pathophysiologic study on methylmalonic aciduria: decrease in liver high-energy phosphate after propionate loading in rats. | 1991 | Pediatr. Res. | pmid:1679919 |
Davies SE et al. | Carnitine therapy and metabolism in the disorders of propionyl-CoA metabolism studied using 1H-NMR spectroscopy. | 1991 | Clin. Chim. Acta | pmid:1819469 |
Levrat MA et al. | High propionic acid fermentations and mineral accumulation in the cecum of rats adapted to different levels of inulin. | 1991 | J. Nutr. | pmid:1941180 |
Ziprin RL et al. | Colonization control of lactose-fermenting Salmonella typhimurium in young broiler chickens by use of dietary lactose. | 1991 | Am. J. Vet. Res. | pmid:1883086 |
Clayson DB et al. | Early indicators of potential neoplasia produced in the rat forestomach by non-genotoxic agents: the importance of induced cellular proliferation. | 1991 | Mutat. Res. | pmid:2046688 |
Fonteriz RI et al. | The role of intracellular acidification in calcium mobilization in human neutrophils. | 1991 | Biochim. Biophys. Acta | pmid:2049405 |
Dawson DA | Additive incidence of developmental malformation for Xenopus embryos exposed to a mixture of ten aliphatic carboxylic acids. | 1991 | Teratology | pmid:1771595 |
Coude MM et al. | Organic acids in aqueous humour and plasma: post mortem study in infants and diagnosis of enzymopathies. | 1991 | J. Inherit. Metab. Dis. | pmid:1779612 |
Yoshino M et al. | Erythematous skin lesions and partial deficiency of 3-methylcrotonyl-CoA carboxylase in peripheral lymphocytes in a patient with propionic acidaemia. | 1991 | J. Inherit. Metab. Dis. | pmid:1779636 |
Barredo MS and Evison LM | Effect of propionate toxicity on methanogen-enriched sludge, Methanobrevibacter smithii, and Methanospirillum hungatii at different pH values. | 1991 | Appl. Environ. Microbiol. | pmid:1872605 |
Faulkner A and Pollock HT | Effect of lactation on gluconeogenesis and ketogenesis in ovine hepatocytes. | 1991 | Comp. Biochem. Physiol., B | pmid:1873985 |
Harrison PT et al. | Early changes in the forestomach of rats, mice and hamsters exposed to dietary propionic and butyric acid. | 1991 | Food Chem. Toxicol. | pmid:1874463 |
Nutting CW et al. | Vasorelaxant effects of short chain fatty acid salts in rat caudal artery. | 1991 | Am. J. Physiol. | pmid:1877681 |
Kamoun PP and Chadefaux B | Eleventh week amniocentesis for prenatal diagnosis of some metabolic diseases. | 1991 | Prenat. Diagn. | pmid:1788175 |
Sumegi B et al. | Is there tight channelling in the tricarboxylic acid cycle metabolon? | 1991 | Biochem. Soc. Trans. | pmid:1794455 |
Kleiner U et al. | [Laboratory studies of Salmonella decontamination in bone meal using propionic acid]. | 1991 | Zentralbl Hyg Umweltmed | pmid:1750967 |
Emery DG et al. | Contributions of sodium and chloride to ultrastructural damage after dendrotomy. | 1991 | Exp Brain Res | pmid:1756799 |
Henly DC and Berry MN | Relationship between the stimulation of citric acid cycle oxidation and the stimulation of fatty acid esterification and inhibition of ketogenesis by lactate in isolated rat hepatocytes. | 1991 | Biochim. Biophys. Acta | pmid:1828700 |
Grotenhuis JT et al. | Bacteriological composition and structure of granular sludge adapted to different substrates. | 1991 | Appl. Environ. Microbiol. | pmid:1892385 |
Rajagopalan R and Altekar W | Products of non-reductive CO2 assimilation in the halophilic archaebacterium Haloferax mediterranei. | 1991 | Indian J. Biochem. Biophys. | pmid:1676015 |
Byck S and Rosenblatt DS | Metabolic cooperation among cell lines from patients with inborn errors of vitamin B12 metabolism: differential response of cblC and cblD. | 1991 | Clin Invest Med | pmid:1676355 |
Kavanagh K et al. | Enhanced intraspecific protoplast fusion in yeast. | 1991 | FEMS Microbiol. Lett. | pmid:1916226 |
Weder AB et al. | Effects of lovastatin treatment on red blood cell and platelet cation transport. | 1991 | Hypertension | pmid:1991653 |
Todesco T et al. | Propionate lowers blood glucose and alters lipid metabolism in healthy subjects. | 1991 | Am. J. Clin. Nutr. | pmid:1951157 |
Barshop BA et al. | Metabolism of 1-13C-propionate in vivo in patients with disorders of propionate metabolism. | 1991 | Pediatr. Res. | pmid:1909779 |
Dutra JC et al. | Effects of methylmalonate and propionate on uptake of glucose and ketone bodies in vitro by brain of developing rats. | 1991 | Biochem. Med. Metab. Biol. | pmid:2015109 |
Vorobjeva LI et al. | Antimutagenicity of propionic acid bacteria. | 1991 | Mutat. Res. | pmid:1720873 |
Ho AK et al. | Intracellular pH on adrenergic-stimulated cAMP and cGMP production in rat pinealocytes. | 1991 | Am. J. Physiol. | pmid:1656768 |
Cherrington CA et al. | Inhibition of Escherichia coli K12 by short-chain organic acids: lack of evidence for induction of the SOS response. | 1991 | J. Appl. Bacteriol. | pmid:2019550 |
Harding BN et al. | Propionic acidaemia: a neuropathological study of two patients presenting in infancy. | 1991 | Neuropathol. Appl. Neurobiol. | pmid:1857488 |
Ferrando R | [Comparative physiology: saturated fatty acids and cholesterolemia in ruminants]. | 1991 Jun-Jul | Bull. Acad. Natl. Med. | pmid:1742626 |
Krahenbuhl S and Brass EP | Inhibition of hepatic propionyl-CoA synthetase activity by organic acids. Reversal of propionate inhibition of pyruvate metabolism. | 1991 Mar 15-Apr 1 | Biochem. Pharmacol. | pmid:2009071 |
Raisuddin S and Misra JK | Aflatoxin in betel nut and its control by use of food preservatives. | 1991 Nov-Dec | Food Addit Contam | pmid:1812017 |
Wehling M et al. | The early mineralocorticoid effector mechanism, the sodium-proton exchanger, is sensitized in lymphocytes from patients with Cushing's syndrome. | 1992 | Clin. Endocrinol. (Oxf) | pmid:1330384 |
Ho AK et al. | Intracellular pH on protein kinase C and ionomycin potentiation of isoproterenol-stimulated cyclic AMP and cyclic GMP production in rat pinealocytes. | 1992 | J. Neurochem. | pmid:1331328 |
Thomas AW et al. | Environmentally directed mutations in the dehalogenase system of Pseudomonas putida strain PP3. | 1992 | Arch. Microbiol. | pmid:1332636 |
Le Ruyet P et al. | Influence of dietary fiber and buffer value index on the ruminal milieu of lactating dairy cows. | 1992 | J. Dairy Sci. | pmid:1333496 |
Tucker WB et al. | Sodium bicarbonate or multielement buffer via diet or rumen: effects on performance and acid-base status of lactating cows. | 1992 | J. Dairy Sci. | pmid:1333497 |
Lapierre L et al. | Lithium chloride-sodium propionate agar for the enumeration of bifidobacteria in fermented dairy products. | 1992 | J. Dairy Sci. | pmid:1317893 |
Brunkhorst BA et al. | Propionate induces polymorphonuclear leukocyte activation and inhibits formylmethionyl-leucyl-phenylalanine-stimulated activation. | 1992 | Infect. Immun. | pmid:1319407 |
Bödeker D and Martens H | Elevated urinary excretion of orotic acid in sheep caused by intraruminal infusion of sodium propionate. | 1992 | Comp. Biochem. Physiol., B | pmid:1617933 |
Kalloghlian A et al. | A patient with propionic acidemia managed with continuous insulin infusion and total parenteral nutrition. | 1992 | J. Child Neurol. | pmid:1588020 |
Harrison PT | Propionic acid and the phenomenon of rodent forestomach tumorigenesis: a review. | 1992 | Food Chem. Toxicol. | pmid:1628870 |
Benjamin IJ et al. | Induction of stress proteins in cultured myogenic cells. Molecular signals for the activation of heat shock transcription factor during ischemia. | 1992 | J. Clin. Invest. | pmid:1569208 |
Deitmer JW | Evidence for glial control of extracellular pH in the leech central nervous system. | 1992 | Glia | pmid:1531809 |
Adjiri D et al. | [In vitro simulation of rabbit cecal fermentation in a semi- continuous flow fermentor. I. Role of food substrate pretreatment]. | 1992 | Reprod. Nutr. Dev. | pmid:1418397 |
Gidenne T and Bellier R | [In vivo study of cecal fermentation activity in the rabbit. Completion and validation of a new technique for cecal cannulation]. | 1992 | Reprod. Nutr. Dev. | pmid:1418398 |
Yasugi T et al. | Formic acid excretion in comparison with methanol excretion in urine of workers occupationally exposed to methanol. | 1992 | Int Arch Occup Environ Health | pmid:1487329 |
Ackermans MT et al. | Determination of propionate in bread using capillary zone electrophoresis. | 1992 | J. Chromatogr. | pmid:1487528 |
Sumegi B et al. | Regulatory consequences of organization of citric acid cycle enzymes. | 1992 | Curr. Top. Cell. Regul. | pmid:1499336 |
Van Bosterhaut B et al. | Three cases of opportunistic infection caused by propionic acid producing Corynebacterium minutissimum. | 1992 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:1396773 |
Finch L and Frederick CB | Rate and route of oxidation of acrylic acid to carbon dioxide in rat liver. | 1992 | Fundam Appl Toxicol | pmid:1426707 |
Sklan D et al. | Fatty acids, calcium soaps of fatty acids, and cottonseeds fed to high yielding cows. | 1992 | J. Dairy Sci. | pmid:1452851 |
Tung RS et al. | In vitro effects of the thiopeptide A10255 on ruminal fermentation and microbial populations. | 1992 | J. Dairy Sci. | pmid:1452854 |
Duncan G et al. | Evidence for a Na(+)-Cl(-)-H(+)-HCO3- exchange system in the mammalian lens. | 1992 | Exp. Eye Res. | pmid:1521584 |
Van Calcar SC et al. | Case reports of successful pregnancy in women with maple syrup urine disease and propionic acidemia. | 1992 | Am. J. Med. Genet. | pmid:1481826 |
Chow JC and Jesse BW | Interactions between gluconeogenesis and fatty acid oxidation in isolated sheep hepatocytes. | 1992 | J. Dairy Sci. | pmid:1401366 |
Holtug K et al. | Effects of propionate on the acid microclimate of hen (Gallus domesticus) colonic mucosa. | 1992 | Comp. Biochem. Physiol. Comp. Physiol. | pmid:1361891 |
Wilkemeyer M et al. | Propionate metabolism in cultured human cells after overexpression of recombinant methylmalonyl CoA mutase: implications for somatic gene therapy. | 1992 | Somat. Cell Mol. Genet. | pmid:1363155 |
Strobel HJ | Vitamin B12-dependent propionate production by the ruminal bacterium Prevotella ruminicola 23. | 1992 | Appl. Environ. Microbiol. | pmid:1637169 |
Ogawa K et al. | Volatile fatty acids, lactic acid, and pH in the stools of breast-fed and bottle-fed infants. | 1992 | J. Pediatr. Gastroenterol. Nutr. | pmid:1432461 |
Gamet L et al. | Effects of short-chain fatty acids on growth and differentiation of the human colon-cancer cell line HT29. | 1992 | Int. J. Cancer | pmid:1521915 |
Shoemaker JD et al. | Misidentification of propionic acid as ethylene glycol in a patient with methylmalonic acidemia. | 1992 | J. Pediatr. | pmid:1538288 |
Friedel D and Levine GM | Effect of short-chain fatty acids on colonic function and structure. | 1992 Jan-Feb | JPEN J Parenter Enteral Nutr | pmid:1738211 |
Scheppach W et al. | Effect of short-chain fatty acids on the human colonic mucosa in vitro. | 1992 Jan-Feb | JPEN J Parenter Enteral Nutr | pmid:1738218 |
Buazzi MM and Marth EH | Sites of action by propionate on Listeria monocytogenes. | 1992 Jan-Feb | Int. J. Food Microbiol. | pmid:1622747 |
McHan F and Shotts EB | Effect of feeding selected short-chain fatty acids on the in vivo attachment of Salmonella typhimurium in chick ceca. | 1992 Jan-Mar | Avian Dis. | pmid:1567301 |
Gessler NN et al. | [Effect of propionate pathway metabolites on the oxidative activity of liver mitochondria under normal conditions and in vitamin B12 deficiency]. | 1992 Jul-Aug | Prikl. Biokhim. Mikrobiol. | pmid:1528821 |
al-Hilli AL and Smith JE | Influence of propionic acid on growth and aflatoxin production by Aspergillus flavus in liquid submerged and solid substrate conditions. | 1992 Mar-Apr | J. Environ. Pathol. Toxicol. Oncol. | pmid:1573566 |
Panfili G et al. | Effect of some food preservatives on aflatoxin production. | 1992 Sep-Oct | Food Addit Contam | pmid:1298645 |
Surtees RA et al. | Neurologic outcome of propionic acidemia. | 1992 Sep-Oct | Pediatr. Neurol. | pmid:1418175 |
Winter SM et al. | Identification and comparison of the urinary metabolites of [1,2,3-13C3]acrylic acid and [1,2,3-13C3]propionic acid in the rat by homonuclear 13C nuclear magnetic resonance spectroscopy. | 1992 Sep-Oct | Drug Metab. Dispos. | pmid:1358570 |
Hurtaud C et al. | Effect of infused volatile fatty acids and caseinate on milk composition and coagulation in dairy cows. | 1993 | J. Dairy Sci. | pmid:8227627 |
Evans CT et al. | [13C]propionate oxidation in wild-type and citrate synthase mutant Escherichia coli: evidence for multiple pathways of propionate utilization. | 1993 | Biochem. J. | pmid:8098211 |
Kolhouse JF et al. | Identification and perturbation of mutant human fibroblasts based on measurements of methylmalonic acid and total homocysteine in the culture media. | 1993 | Arch. Biochem. Biophys. | pmid:8099783 |
Katsura K et al. | Buffer capacity of rat cortical tissue as well as of cultured neurons and astrocytes. | 1993 | Brain Res. | pmid:8374759 |
Salvador V et al. | Sugar composition of dietary fibre and short-chain fatty acid production during in vitro fermentation by human bacteria. | 1993 | Br. J. Nutr. | pmid:8399101 |
Farningham DA and Whyte CC | The role of propionate and acetate in the control of food intake in sheep. | 1993 | Br. J. Nutr. | pmid:8399117 |
Werlin SL | E. coli sepsis as a presenting sign in neonatal propionic acidemia. | 1993 | Am. J. Med. Genet. | pmid:8357022 |
Stankovics J and Ledley FD | Cloning of functional alpha propionyl CoA carboxylase and correction of enzyme deficiency in pccA fibroblasts. | 1993 | Am. J. Hum. Genet. | pmid:8434582 |
Goff JP and Horst RL | Oral administration of calcium salts for treatment of hypocalcemia in cattle. | 1993 | J. Dairy Sci. | pmid:8436668 |
Sallaz M and Jourdan F | C-fos expression and 2-deoxyglucose uptake in the olfactory bulb of odour-stimulated awake rats. | 1993 | Neuroreport | pmid:8453036 |
Thurman PF et al. | Possible intermediates in the biosynthesis of mycoside B by Mycobacterium microti. | 1993 | Eur. J. Biochem. | pmid:8462544 |
Russell JB and Chow JM | Another theory for the action of ruminal buffer salts: decreased starch fermentation and propionate production. | 1993 | J. Dairy Sci. | pmid:8463492 |
Farningham DA et al. | Satiety signals in sheep: involvement of CCK, propionate, and vagal CCK binding sites. | 1993 | Physiol. Behav. | pmid:8415934 |
Fedotcheva NI et al. | [Metabolites of the propionate pathway as regulators of fatty and dicarboxylic acid oxidation in liver mitochondria]. | 1993 | Biokhimiia | pmid:8507736 |
GarcÃa-MartÃnez LF and Appling DR | Characterization of the folate-dependent mitochondrial oxidation of carbon 3 of serine. | 1993 | Biochemistry | pmid:8485144 |
Pell AN and Schofield P | Computerized monitoring of gas production to measure forage digestion in vitro. | 1993 | J. Dairy Sci. | pmid:8486838 |
Liu CM et al. | Elaiophylin as a rumen fermentation efficiency enhancer. | 1993 | J. Antibiot. | pmid:8468252 |
Sano H et al. | Plasma insulin and glucagon responses to intravenous infusion of propionate and their autonomic control in sheep. | 1993 | J. Anim. Sci. | pmid:7904990 |