propionic acid is a lipid of Fatty Acyls (FA) class. Propionic acid is associated with abnormalities such as Epilepsy, Infection, Tuberculosis, Alkalosis and Ischemia. The involved functions are known as Uptake, Biosynthetic Pathways, Methylation, Protein Overexpression and Biochemical Pathway. Propionic acid often locates in Body tissue, Cytoplasmic matrix, Membrane, Protoplasm and Extracellular. The associated genes with propionic acid are TRIO gene, TRRAP gene, SLC5A8 gene, SLC33A1 gene and Homologous Gene. The related lipids are Fatty Acids, Propionate, butyrate, Valerates and mycocerosic acid.
To understand associated biological information of propionic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
propionic acid is suspected in Propionic acidemia, Ischemia, Infection, Ulcerative Colitis, Alkalosis, Methylmalonic acidemia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with propionic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Cantenys D et al. | Covalent attachment of insulin to the outer surface of liposomes. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6197974 |
Staecker JL et al. | Stimulation of DNA synthesis in primary cultures of adult rat hepatocytes by sodium butyrate. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3632683 |
Rabier D et al. | Propionate and succinate effects on acetyl glutamate biosynthesis by rat liver mitochondria. | 1979 | Biochem. Biophys. Res. Commun. | pmid:518644 |
Willard HF and Rosenberg LE | Inborn errors of cobalamin metabolism: effect of cobalamin supplementation in culture on methylmalonyl CoA mutase activity in normal and mutant human fibroblasts. | 1979 | Biochem. Genet. | pmid:36882 |
Ruvolo-Takasusuki MC and Collet T | Characterization of Nasutitermes globiceps (Isoptera: Termitidae) esterases. | 2000 | Biochem. Genet. | pmid:11301915 |
Sugden MC et al. | Odd-carbon fatty acid metabolism in hepatocytes from starved rats. | 1984 | Biochem. Int. | pmid:6477599 |
Prasad R and Höfer M | The electrochemical gradient of H+ in Candida albicans and its relevance to the uptake of nutrients. | 1987 | Biochem. Int. | pmid:2839177 |
Genet R and Lederer F | The carbanion of nitroethane is an inhibitor of, and not a substrate for, flavocytochrome b2 [L-(+)-lactate dehydrogenase]. | 1990 | Biochem. J. | pmid:2178603 |
Scott DA et al. | Ca2+ storage in Trypanosoma brucei: the influence of cytoplasmic pH and importance of vacuolar acidity. | 1995 | Biochem. J. | pmid:7575411 |
O'Keeffe DT and Anthony C | The two cytochromes c in the facultative methylotroph Pseudomonas am1. | 1980 | Biochem. J. | pmid:6263253 |
Arinze IJ and Rowley DL | Gluconeogenesis by isolated guinea-pig liver parenchymal cells. | 1975 | Biochem. J. | pmid:177003 |
Timkovich R | Chemical modification of the haem propionate of cytochrome c. | 1980 | Biochem. J. | pmid:6246879 |
Clark MG et al. | Gluconeogenesis in isolated intact lamb liver cells. Effects of glucagon and butyrate. | 1976 | Biochem. J. | pmid:949349 |
Hashimoto S and Hayakawa S | Microbiological degradation of bile acids. Metabolites formed from 3-(3a alpha-hexahydro-7a beta-methyl-1,5-dioxoindan-4 alpha-yl) propionic acid by Streptomyces rubescens. | 1977 | Biochem. J. | pmid:883963 |
Lomax MA et al. | The control of fatty acid metabolism in liver cells from fed and starved sheep. | 1983 | Biochem. J. | pmid:6615480 |
Ghosh NK et al. | Induction of human choriogonadotropin in heLa-cell cultures by aliphatic monocarboxylates and inhibitors of deoxyribonucleic acid synthesis. | 1977 | Biochem. J. | pmid:911320 |
Scholem RD and Brown GK | Metabolism of malonic semialdehyde in man. | 1983 | Biochem. J. | pmid:6418146 |
Zaleski J and Bryła J | Effect of alloxan-diabetes on gluconeogenesis and ureogenesis in isolated rabbit liver cells. | 1978 | Biochem. J. | pmid:743258 |
Elder GH et al. | Factors determining the sequence of oxidative decarboxylation of the 2- and 4-propionate substituents of coproporphyrinogen III by coproporphyrinogen oxidase in rat liver. | 1978 | Biochem. J. | pmid:629747 |
Evans CT et al. | [13C]propionate oxidation in wild-type and citrate synthase mutant Escherichia coli: evidence for multiple pathways of propionate utilization. | 1993 | Biochem. J. | pmid:8098211 |
Seehra JS et al. | Anaerobic and aerobic coproporphyrinogen III oxidases of Rhodopseudomonas spheroides. Mechanism and stereochemistry of vinyl group formation. | 1983 | Biochem. J. | pmid:6603215 |
Shepherd M et al. | Purification and kinetic characterization of the magnesium protoporphyrin IX methyltransferase from Synechocystis PCC6803. | 2003 | Biochem. J. | pmid:12489983 |
Bell SC and Turner JM | Bacterial catabolism of threonine. Threonine degradation initiated by l-threonine hydrolyase (deaminating) in a species of Corynebacterium. | 1977 | Biochem. J. | pmid:16743051 |
Lomax MA et al. | Differences between lactating and non-lactating dairy cows in concentration and secretion rate of insulin. | 1979 | Biochem. J. | pmid:486110 |
Schwab MA et al. | Secondary mitochondrial dysfunction in propionic aciduria: a pathogenic role for endogenous mitochondrial toxins. | 2006 | Biochem. J. | pmid:16686602 |
Baird GD et al. | Net hepatic and splanchnic metabolism of lactate, pyruvate and propionate in dairy cows in vivo in relation to lactation and nutrient supply. | 1980 | Biochem. J. | pmid:6989361 |
Girvan HM et al. | Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3. | 2010 | Biochem. J. | pmid:20180779 |
JAMES AT et al. | The metabolism of propionic acid. | 1956 | Biochem. J. | pmid:13382825 |
Williams DL et al. | Metabolic effects of propionate administration to normal and vitamin B12-deficient rats. | 1971 | Biochem. J. | pmid:5116531 |
Nyhan WL et al. | Tiglicaciduria in propionicacidaemia. | 1972 | Biochem. J. | pmid:5073234 |
Chan TM and Freedland RA | The effect of propionate on the metabolism of pyruvate and lactate in the perfused rat liver. | 1972 | Biochem. J. | pmid:5076196 |
Ryan JP and Ryan H | The role of intracellular pH in the regulation of cation exchanges in yeast. | 1972 | Biochem. J. | pmid:4563763 |
Williams DL et al. | Metabolic effects of propionate in normal and vitamin B 12 -deficient rats. | 1971 | Biochem. J. | pmid:5135236 |
Malaisse WJ et al. | Enzyme-to-enzyme channelling of Krebs cycle metabolic intermediates in Caco-2 cells exposed to [2-13c]propionate. | 1996 | Biochem. J. | pmid:8760374 |
Srinivas SR et al. | Cloning and functional identification of slc5a12 as a sodium-coupled low-affinity transporter for monocarboxylates (SMCT2). | 2005 | Biochem. J. | pmid:16104846 |
Jones A and Turner JM | Microbial metabolism of amino alcohols. 1-Aminopropan-2-ol and ethanolamine metabolism via propionaldehyde and acetaldehyde in a species of Pseudomonas. | 1973 | Biochem. J. | pmid:4723219 |
Narumi K et al. | Biosynthesis of a mycobacterial lipopolysaccharide. Incorporation of (14C)acyl groups by whole cells in vivo. | 1973 | Biochem. J. | pmid:4725042 |
STORRY JE and ROOK JA | EFFECT IN THE COW OF INTRARUMINAL INFUSIONS OF VOLATILE FATTY ACIDS AND OF LACTIC ACID ON THE SECRETION OF THE COMPONENT FATTY ACIDS OF THE MILK FAT AND ON THE COMPOSITION OF BLOOD. | 1965 | Biochem. J. | pmid:14343134 |
Black KM et al. | Conserved tryptophan in cytochrome c: importance of the unique side-chain features of the indole moiety. | 2001 | Biochem. J. | pmid:11672447 |
Hiltunen JK | Metabolic effects of pent-4-enoate in isolated perfused rat heart. | 1978 | Biochem. J. | pmid:637839 |
Grunnet N and Katz J | Effects of ammonia and norvaline on lactate metabolism by hepatocytes from starved rats. The use of 14C-labelled lactate in studies of hepatic gluconeogenesis. | 1978 | Biochem. J. | pmid:687361 |
Killilea SD et al. | Structures and apoprotein linkages of phycoerythrobilin and phycocyanobilin. | 1980 | Biochem. J. | pmid:7396852 |
Pappu AS et al. | Possible interrelationship between vitamins E and b12 in the disturbance in methylmalonate metabolism in vitamin E deficiency. | 1978 | Biochem. J. | pmid:656065 |
Lomax MA et al. | The effect of fatty acids and starvation on the metabolism of gluconeogenic precursors by isolated sheep liver cells. | 1986 | Biochem. J. | pmid:3827848 |
Killilea SD and O'Carra P | Structure and apoprotein linkages of phycourobilin. | 1985 | Biochem. J. | pmid:3838665 |
Iwaki A and Izawa S | Acidic stress induces the formation of P-bodies, but not stress granules, with mild attenuation of bulk translation in Saccharomyces cerevisiae. | 2012 | Biochem. J. | pmid:22686455 |
Sumegi B et al. | Metabolism of [3-13C]pyruvate and [3-13C]propionate in normal and ischaemic rat heart in vivo: 1H- and 13C-NMR studies. | 1995 | Biochem. J. | pmid:7492338 |
Koshihara Y et al. | Effect of sodium n-butyrate on induction of prostaglandin synthase activity in cloned mastocytoma P-815 2-E-6 cells. | 1981 | Biochem. J. | pmid:6796055 |
Arinze IJ et al. | Effect of methylamalonic acid on gluconeogenesis in isolated rat and guinea-pig hepatocytes. | 1979 | Biochem. J. | pmid:540062 |
Shepherd M and Hunter CN | Transient kinetics of the reaction catalysed by magnesium protoporphyrin IX methyltransferase. | 2004 | Biochem. J. | pmid:15239672 |