propionic acid

propionic acid is a lipid of Fatty Acyls (FA) class. Propionic acid is associated with abnormalities such as Epilepsy, Infection, Tuberculosis, Alkalosis and Ischemia. The involved functions are known as Uptake, Biosynthetic Pathways, Methylation, Protein Overexpression and Biochemical Pathway. Propionic acid often locates in Body tissue, Cytoplasmic matrix, Membrane, Protoplasm and Extracellular. The associated genes with propionic acid are TRIO gene, TRRAP gene, SLC5A8 gene, SLC33A1 gene and Homologous Gene. The related lipids are Fatty Acids, Propionate, butyrate, Valerates and mycocerosic acid.

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Introduction

To understand associated biological information of propionic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with propionic acid?

propionic acid is suspected in Propionic acidemia, Ischemia, Infection, Ulcerative Colitis, Alkalosis, Methylmalonic acidemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with propionic acid

MeSH term MeSH ID Detail
Dysbiosis D064806 2 associated lipids
Propionic Acidemia D056693 3 associated lipids
Tendinopathy D052256 3 associated lipids
Atherosclerosis D050197 85 associated lipids
Colitis, Microscopic D046728 1 associated lipids
HIV-Associated Lipodystrophy Syndrome D039682 3 associated lipids
Poult Enteritis Mortality Syndrome D031261 1 associated lipids
Mitochondrial Diseases D028361 25 associated lipids
Hyperammonemia D022124 5 associated lipids
Diffuse Axonal Injury D020833 1 associated lipids
Fetal Weight D020567 12 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Gait Disorders, Neurologic D020233 3 associated lipids
Brain Injury, Chronic D020208 1 associated lipids
Sleep Apnea, Obstructive D020181 9 associated lipids
Ornithine Carbamoyltransferase Deficiency Disease D020163 2 associated lipids
Genetic Predisposition to Disease D020022 24 associated lipids
Placenta, Retained D018457 3 associated lipids
Vasculitis, Leukocytoclastic, Cutaneous D018366 5 associated lipids
Carcinoma, Embryonal D018236 8 associated lipids
Hepatoblastoma D018197 10 associated lipids
Dermatitis, Photoallergic D017454 3 associated lipids
Gram-Positive Bacterial Infections D016908 3 associated lipids
Leukemia, Lymphocytic, Chronic, B-Cell D015451 25 associated lipids
Weight Gain D015430 101 associated lipids
Zoonoses D015047 3 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Ventricular Fibrillation D014693 16 associated lipids
Vaginitis D014627 6 associated lipids
Uveitis D014605 14 associated lipids
Treponemal Infections D014211 3 associated lipids
Tooth, Impacted D014095 9 associated lipids
Tooth Migration D014085 2 associated lipids
Tinea D014005 5 associated lipids
Testicular Neoplasms D013736 5 associated lipids
Androgen-Insensitivity Syndrome D013734 1 associated lipids
Telangiectasis D013684 2 associated lipids
Stomatitis D013280 14 associated lipids
Stomach Ulcer D013276 75 associated lipids
Stomach Neoplasms D013274 24 associated lipids
Stevens-Johnson Syndrome D013262 3 associated lipids
Starvation D013217 47 associated lipids
Skin Diseases, Metabolic D012875 2 associated lipids
Seizures D012640 87 associated lipids
Sarcoma, Experimental D012513 13 associated lipids
Salmonella Infections, Animal D012481 9 associated lipids
Rickets D012279 6 associated lipids
Reye Syndrome D012202 14 associated lipids
Puerperal Disorders D011644 4 associated lipids
Puberty, Delayed D011628 1 associated lipids
Proteinuria D011507 30 associated lipids
Poultry Diseases D011201 21 associated lipids
Phenylketonurias D010661 7 associated lipids
Peritonitis D010538 38 associated lipids
Periodontitis D010518 22 associated lipids
Parturient Paresis D010319 2 associated lipids
Pain, Postoperative D010149 13 associated lipids
Pain D010146 64 associated lipids
Ostertagiasis D010029 2 associated lipids
Osteolysis D010014 8 associated lipids
Opportunistic Infections D009894 8 associated lipids
Occupational Diseases D009784 42 associated lipids
Dermatitis, Occupational D009783 12 associated lipids
Nerve Degeneration D009410 53 associated lipids
Mushroom Poisoning D009145 3 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Malabsorption Syndromes D008286 16 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Liver Abscess D008100 6 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Leukemia D007938 74 associated lipids
Kidney Neoplasms D007680 29 associated lipids
Keratosis D007642 9 associated lipids
Ischemia D007511 18 associated lipids
Ileitis D007079 2 associated lipids
Hypertension D006973 115 associated lipids
Hyperplasia D006965 34 associated lipids
Hyperlipidemias D006949 73 associated lipids
Hyperinsulinism D006946 27 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Homocystinuria D006712 2 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Hemolysis D006461 131 associated lipids
Hemoglobinopathies D006453 7 associated lipids
Heart Failure D006333 36 associated lipids
Cardiomegaly D006332 31 associated lipids
Growth Disorders D006130 5 associated lipids
Glycosuria D006029 10 associated lipids
Glioma D005910 112 associated lipids
Gingival Diseases D005882 1 associated lipids
Galactosemias D005693 5 associated lipids
Fructose Intolerance D005633 1 associated lipids
Foot-and-Mouth Disease D005536 1 associated lipids
Foot Dermatoses D005533 3 associated lipids
Farmer's Lung D005203 2 associated lipids
Erythema D004890 22 associated lipids
Ergotism D004881 4 associated lipids
Epistaxis D004844 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with propionic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with propionic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with propionic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with propionic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with propionic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with propionic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with propionic acid

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Authors Title Published Journal PubMed Link
Murphy ER et al. Impulsive behaviour induced by both NMDA receptor antagonism and GABAA receptor activation in rat ventromedial prefrontal cortex. 2012 Psychopharmacology (Berl.) pmid:22101355
Pałucha-Poniewiera A et al. On the mechanism of the antidepressant-like action of group II mGlu receptor antagonist, MGS0039. 2010 Psychopharmacology (Berl.) pmid:20703449
Santos PM and Sá-Correia I Adaptation to beta-myrcene catabolism in Pseudomonas sp. M1: an expression proteomics analysis. 2009 Proteomics pmid:19798672
Zhang J et al. Protein profile in neuroblastoma cells incubated with S- and R-enantiomers of ibuprofen by iTRAQ-coupled 2-D LC-MS/MS analysis: possible action of induced proteins on Alzheimer's disease. 2008 Proteomics pmid:18351690
Diedrich M et al. Brain region specific mitophagy capacity could contribute to selective neuronal vulnerability in Parkinson's disease. 2011 Proteome Sci pmid:21943346
Smith LJ et al. Molecular dynamics simulations of Hydrogenobacter thermophilus cytochrome c552: comparisons of the wild-type protein, a b-type variant, and the apo state. 2006 Proteins pmid:16981201
Bento I et al. Molecular basis for redox-Bohr and cooperative effects in cytochrome c3 from Desulfovibrio desulfuricans ATCC 27774: crystallographic and modeling studies of oxidized and reduced high-resolution structures at pH 7.6. 2004 Proteins pmid:14705030
Fufezan C et al. Ligand preference and orientation in b- and c-type heme-binding proteins. 2008 Proteins pmid:18491383
Stjernschantz E et al. Structural rationalization of novel drug metabolizing mutants of cytochrome P450 BM3. 2008 Proteins pmid:17957765
Simanshu DK et al. Crystal structures of Salmonella typhimurium propionate kinase and its complex with Ap4A: evidence for a novel Ap4A synthetic activity. 2008 Proteins pmid:17894350
Zubieta C et al. Identification and structural characterization of heme binding in a novel dye-decolorizing peroxidase, TyrA. 2007 Proteins pmid:17654547
Qian C et al. Effects of charged amino-acid mutation on the solution structure of cytochrome b(5) and binding between cytochrome b(5) and cytochrome c. 2001 Protein Sci. pmid:11714912
Stephenson JR et al. Role of aspartate 400, arginine 262, and arginine 401 in the catalytic mechanism of human coproporphyrinogen oxidase. 2007 Protein Sci. pmid:17242372
Sode K et al. Propionate sensor using coenzyme-A transferase and acyl-CoA oxidase. 2008 Protein Pept. Lett. pmid:18855748
Miller GT et al. Expression of Pseudomonas stutzeri Zobell cytochrome c-551 and its H47A variant in Escherichia coli. 2003 Protein Expr. Purif. pmid:12767816
Takahashi K et al. Expression and characterization of frog peptidylglycine alpha-hydroxylating monooxygenase. 2003 Protein Expr. Purif. pmid:12509982
Mustata G and Briggs JM Cluster analysis of water molecules in alanine racemase and their putative structural role. 2004 Protein Eng. Des. Sel. pmid:15115851
Appleton RA and Brown K Conformational requirements at the prostaglandin cyclooxygenase receptor site: a template for designing non-steroidal anti-inflammatory drugs. 1979 Prostaglandins pmid:118488
Powell JG and Cochrane RL The effects of a number of non-steroidal anti-inflammatory compounds on parturition in the rat. 1982 Prostaglandins pmid:7202240
Juszczak GR and Swiergiel AH Properties of gap junction blockers and their behavioural, cognitive and electrophysiological effects: animal and human studies. 2009 Prog. Neuropsychopharmacol. Biol. Psychiatry pmid:19162118
Ninio DM and Saint DA The role of stretch-activated channels in atrial fibrillation and the impact of intracellular acidosis. Prog. Biophys. Mol. Biol. pmid:18367236
Burnard DM and MacVicar BA Electrophysiological properties of glial cells are altered by propionate and barium-tetraethylammonium (TEA). 1987 Proc. West. Pharmacol. Soc. pmid:2442772
Anderson JW and Bridges SR Short-chain fatty acid fermentation products of plant fiber affect glucose metabolism of isolated rat hepatocytes. 1984 Proc. Soc. Exp. Biol. Med. pmid:6091151
Chen WJ et al. Propionate may mediate the hypocholesterolemic effects of certain soluble plant fibers in cholesterol-fed rats. 1984 Proc. Soc. Exp. Biol. Med. pmid:6320209
Hsu P et al. pHi in piglet cerebral microvascular endothelial cells: recovery from an acid load. 1996 Proc. Soc. Exp. Biol. Med. pmid:8677271
Chan TM and Freedland RA Effects of glucagon on gluconeogenesis from lactate and propionate in the perfused rat liver. 1976 Proc. Soc. Exp. Biol. Med. pmid:1250874
SMITH MS and WAIN RL The plant growth-regulating activity of dextro and laevo alpha-(2-naphthoxy) propionic acid. 1951 Proc. R. Soc. Lond., B, Biol. Sci. pmid:14911818
Paroder V et al. Na(+)/monocarboxylate transport (SMCT) protein expression correlates with survival in colon cancer: molecular characterization of SMCT. 2006 Proc. Natl. Acad. Sci. U.S.A. pmid:16670197
Tabita FR The hydroxypropionate pathway of CO2 fixation: Fait accompli. 2009 Proc. Natl. Acad. Sci. U.S.A. pmid:19996176
Rowe WA et al. Polarized Na+/H+ exchange function is pliable in response to transepithelial gradients of propionate. 1994 Proc. Natl. Acad. Sci. U.S.A. pmid:8016132
Xiong Y et al. Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41. 2004 Proc. Natl. Acad. Sci. U.S.A. pmid:14722361
Ebbing MH et al. Resorcinarenes with 2-benzimidazolone bridges: self-aggregation, self-assembled dimeric capsules, and guest encapsulation. 2002 Proc. Natl. Acad. Sci. U.S.A. pmid:11959947
Jain M et al. Lipidomics reveals control of Mycobacterium tuberculosis virulence lipids via metabolic coupling. 2007 Proc. Natl. Acad. Sci. U.S.A. pmid:17360366
Pluznick JL et al. Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation. 2013 Proc. Natl. Acad. Sci. U.S.A. pmid:23401498
Barnes AI et al. Feeding, fecundity and lifespan in female Drosophila melanogaster. 2008 Proc. Biol. Sci. pmid:18430646
Pouteau E et al. Production rates and metabolism of short-chain fatty acids in the colon and whole body using stable isotopes. 2003 Proc Nutr Soc pmid:12740063
Macfarlane S and Macfarlane GT Regulation of short-chain fatty acid production. 2003 Proc Nutr Soc pmid:12740060
Anil MH and Forbes JM Disruption of feeding behaviour in sheep by portal vein infusions of mixed volatile fatty acids or propionate. 1977 Proc Nutr Soc pmid:905303
Garton GA et al. Effect of dietary propionate on the fatty acid composition of lamb triglycerides. 1972 Proc Nutr Soc pmid:5048471
Darzi J et al. Do SCFA have a role in appetite regulation? 2011 Proc Nutr Soc pmid:21266094
Allen MS and Bradford BJ Control of food intake by metabolism of fuels: a comparison across species. 2012 Proc Nutr Soc pmid:22704548
Weekes TE and Webster AJ Metabolism of propionate by the portal-drained viscera in sheep. 1974 Proc Nutr Soc pmid:4459973
Chalmers JS et al. The effect of intraruminal infusions of propionic acid on milk composition in cows given silage diets. 1980 Proc Nutr Soc pmid:7403069
Delzenne NM Oligosaccharides: state of the art. 2003 Proc Nutr Soc pmid:12749343
Koen E [Polarographic method of determining microconcentrations of styrene in the air]. 1981 Probl Khig pmid:7301804
Nefelova MV et al. [Directed synthesis of macrotetrolides]. 1987 Nov-Dec Prikl. Biokhim. Mikrobiol. pmid:3444814
Danilova IV et al. [A positive effect of Propionibacterium freudenreichii on the growth of Saccharomyces cerevisiae during their cocultivation]. 2006 Jul-Aug Prikl. Biokhim. Mikrobiol. pmid:17022451
Stoianova LG et al. [Desugarization of egg white by microorganisms]. 1976 Jul-Aug Prikl. Biokhim. Mikrobiol. pmid:17113
Poluliakh OV et al. [Conditions for porphyrin formation by propionic acid bacteria]. 1985 Mar-Apr Prikl. Biokhim. Mikrobiol. pmid:3991478
Borisova TG et al. [Propionic acid bacteria phage]. 1973 Mar-Apr Prikl. Biokhim. Mikrobiol. pmid:4771039