propionic acid is a lipid of Fatty Acyls (FA) class. Propionic acid is associated with abnormalities such as Epilepsy, Infection, Tuberculosis, Alkalosis and Ischemia. The involved functions are known as Uptake, Biosynthetic Pathways, Methylation, Protein Overexpression and Biochemical Pathway. Propionic acid often locates in Body tissue, Cytoplasmic matrix, Membrane, Protoplasm and Extracellular. The associated genes with propionic acid are TRIO gene, TRRAP gene, SLC5A8 gene, SLC33A1 gene and Homologous Gene. The related lipids are Fatty Acids, Propionate, butyrate, Valerates and mycocerosic acid.
To understand associated biological information of propionic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
propionic acid is suspected in Propionic acidemia, Ischemia, Infection, Ulcerative Colitis, Alkalosis, Methylmalonic acidemia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with propionic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Robertson MD et al. | Insulin-sensitizing effects of dietary resistant starch and effects on skeletal muscle and adipose tissue metabolism. | 2005 | Am. J. Clin. Nutr. | pmid:16155268 |
Wolever TM et al. | Propionate inhibits incorporation of colonic [1,2-13C]acetate into plasma lipids in humans. | 1995 | Am. J. Clin. Nutr. | pmid:7762524 |
Todesco T et al. | Propionate lowers blood glucose and alters lipid metabolism in healthy subjects. | 1991 | Am. J. Clin. Nutr. | pmid:1951157 |
Liljeberg HG and Björck IM | Delayed gastric emptying rate as a potential mechanism for lowered glycemia after eating sourdough bread: studies in humans and rats using test products with added organic acids or an organic salt. | 1996 | Am. J. Clin. Nutr. | pmid:8942413 |
McIntosh GH et al. | Whole-grain rye and wheat foods and markers of bowel health in overweight middle-aged men. | 2003 | Am. J. Clin. Nutr. | pmid:12663299 |
Weitkunat K et al. | Odd-chain fatty acids as a biomarker for dietary fiber intake: a novel pathway for endogenous production from propionate. | 2017 | Am. J. Clin. Nutr. | pmid:28424190 |
Pigatto P et al. | Cross-reactions in patch testing and photopatch testing with ketoprofen, thiaprophenic acid, and cinnamic aldehyde. | 1996 | Am. J. Contact Dermatitis | pmid:8955484 |
Patz J et al. | Treatment of refractory distal ulcerative colitis with short chain fatty acid enemas. | 1996 | Am. J. Gastroenterol. | pmid:8677939 |
Stolc V | Inhibitory effect of short-chain aliphatic acids on deoxythymidine incorporation into DNA in mitogen-stimulated and leukemic lymphocytes. | 1982 | Am. J. Hematol. | pmid:7137170 |
Ravn K et al. | High incidence of propionic acidemia in greenland is due to a prevalent mutation, 1540insCCC, in the gene for the beta-subunit of propionyl CoA carboxylase. | 2000 | Am. J. Hum. Genet. | pmid:10820128 |