propionic acid is a lipid of Fatty Acyls (FA) class. Propionic acid is associated with abnormalities such as Epilepsy, Infection, Tuberculosis, Alkalosis and Ischemia. The involved functions are known as Uptake, Biosynthetic Pathways, Methylation, Protein Overexpression and Biochemical Pathway. Propionic acid often locates in Body tissue, Cytoplasmic matrix, Membrane, Protoplasm and Extracellular. The associated genes with propionic acid are TRIO gene, TRRAP gene, SLC5A8 gene, SLC33A1 gene and Homologous Gene. The related lipids are Fatty Acids, Propionate, butyrate, Valerates and mycocerosic acid.
To understand associated biological information of propionic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
propionic acid is suspected in Propionic acidemia, Ischemia, Infection, Ulcerative Colitis, Alkalosis, Methylmalonic acidemia and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with propionic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Di Lisa F et al. | Contrasting effects of propionate and propionyl-L-carnitine on energy-linked processes in ischemic hearts. | 1994 | Am. J. Physiol. | pmid:8067396 |
Bidani A and Heming TA | Kinetic analysis of cytosolic pH regulation in alveolar macrophages: V-ATPase-mediated responses to a weak acid. | 1995 | Am. J. Physiol. | pmid:7631810 |
Garvey MH and Maude DL | Acid excretion by bicarbonate-free perfused rat kidney. | 1981 | Am. J. Physiol. | pmid:6784580 |
Harada E and Kato S | Effect of short-chain fatty acids on the secretory response of the ovine exocrine pancreas. | 1983 | Am. J. Physiol. | pmid:6187225 |
El-Sharkaway TY and Daniel EE | Ionic mechanisms of intestinal electrical control activity. | 1975 | Am. J. Physiol. | pmid:1200148 |
Nutting CW et al. | Vasorelaxant effects of short chain fatty acid salts in rat caudal artery. | 1991 | Am. J. Physiol. | pmid:1877681 |
Conn AR et al. | Characterization of alpha-keto acid transport across blood-brain barrier in rats. | 1983 | Am. J. Physiol. | pmid:6614164 |
Petersen KU and Reuss L | Electrophysiological effects of propionate and bicarbonate on gallbladder epithelium. | 1985 | Am. J. Physiol. | pmid:2981476 |
Harada E et al. | Potentiation of carbachol-induced amylase release by propionate in guinea pig and vole pancreatic acini. | 1999 | Am. J. Physiol. | pmid:10484494 |
Rabinowitz L et al. | Effects of glucagon, insulin, propionate, acetate, and HCO3 on K excretion in sheep. | 1984 | Am. J. Physiol. | pmid:6320683 |
Feldman GM et al. | Propionate induces cell swelling and K+ accumulation in shark rectal gland. | 1989 | Am. J. Physiol. | pmid:2548391 |
Rowe WA et al. | Propionate activates multiple ion transport mechanisms in the HT29-18-C1 human colon cell line. | 1993 | Am. J. Physiol. | pmid:8214077 |
Harris JB et al. | Lipoate effect on carbohydrate and lipid metabolism and gastric H+ secretion. | 1975 | Am. J. Physiol. | pmid:1090192 |
Pi-Sunyer FX et al. | Glucagon, insulin, and gluconeogenesis in fasted odd carbon fatty acid-enriched rats. | 1976 | Am. J. Physiol. | pmid:961887 |
Keifer DW | Effect of weak acids on pH regulation and anion transport in barnacle muscle fibers. | 1981 | Am. J. Physiol. | pmid:7304732 |
Ho AK et al. | Intracellular pH on adrenergic-stimulated cAMP and cGMP production in rat pinealocytes. | 1991 | Am. J. Physiol. | pmid:1656768 |
Toda N | Mechanical responses of isolated dog cerebral arteries to reduction of external K, Na, and Cl. | 1978 | Am. J. Physiol. | pmid:645879 |
Grinstein S and Furuya W | Characterization of the amiloride-sensitive Na+-H+ antiport of human neutrophils. | 1986 | Am. J. Physiol. | pmid:3953781 |
Szczepańska M and Angielski S | Prevention of maleate-induced tubular dysfunction by acetoacetate. | 1980 | Am. J. Physiol. | pmid:7395994 |
Suarez-Kurtz G and Eastwood AB | Release of sarcoplasmic enzymes from frog skeletal muscle. | 1981 | Am. J. Physiol. | pmid:6792928 |