Lipoxin a4 is a lipid of Fatty Acyls (FA) class. Lipoxin a4 is associated with abnormalities such as Asthma, Cystic Fibrosis, Pneumonia, Obesity and Septicemia. The involved functions are known as Inflammation, Signal, Signal Transduction, Regulation and Metabolic Inhibition. Lipoxin a4 often locates in Immune system, Blood, soluble, Extracellular and Splenic Tissue. The associated genes with Lipoxin A4 are FPR2 gene, Homologous Gene, SAA1 gene, Trp-Lys-Tyr-Met-Val-Met and Annexin 1. The related lipids are Steroids. The related experimental models are Knock-out.
To understand associated biological information of Lipoxin A4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Lipoxin A4 is suspected in Asthma, Cystic Fibrosis, Chagas Cardiomyopathy, Pneumonia, Obesity, Septicemia and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Lipoxin A4
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Knock-out are used in the study 'Aspirin-triggered 15-epi-lipoxin A4 regulates neutrophil-platelet aggregation and attenuates acute lung injury in mice.' (Ortiz-Muñoz G et al., 2014).
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Authors | Title | Published | Journal | PubMed Link |
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Martini AC et al. | Neuroprotective effects of lipoxin A4 in central nervous system pathologies. | 2014 | Biomed Res Int | pmid:25276776 |
Yang F et al. | Regional arterial infusion with lipoxin A4 attenuates experimental severe acute pancreatitis. | 2014 | PLoS ONE | pmid:25265022 |
Ono E et al. | Lipoxin generation is related to soluble epoxide hydrolase activity in severe asthma. | 2014 | Am. J. Respir. Crit. Care Med. | pmid:25162465 |
Ortiz-Muñoz G et al. | Aspirin-triggered 15-epi-lipoxin A4 regulates neutrophil-platelet aggregation and attenuates acute lung injury in mice. | 2014 | Blood | pmid:25143486 |
Andersson P et al. | Inhibition of neutrophil-dependent cytotoxicity for human endothelial cells by ACE inhibitors. | 2014 | Scand. J. Immunol. | pmid:25124788 |
Wu R et al. | Lipoxin A4 suppresses the development of endometriosis in an ALX receptor-dependent manner via the p38 MAPK pathway. | 2014 | Br. J. Pharmacol. | pmid:24923883 |
Zhou XL et al. | Protective effects of lipoxin A4 in testis injury following testicular torsion and detorsion in rats. | 2014 | Mediators Inflamm. | pmid:24904198 |
Martin CR et al. | Resolvin D1 and lipoxin A4 improve alveolarization and normalize septal wall thickness in a neonatal murine model of hyperoxia-induced lung injury. | 2014 | PLoS ONE | pmid:24892762 |
Yao C et al. | Aspirin-triggered lipoxin A4 attenuates lipopolysaccharide induced inflammatory response in primary astrocytes. | 2014 | Int. Immunopharmacol. | pmid:24269179 |
Ramon S et al. | Lipoxin Aâ‚„ modulates adaptive immunity by decreasing memory B-cell responses via an ALX/FPR2-dependent mechanism. | 2014 | Eur. J. Immunol. | pmid:24166736 |