Lipoxin A4

Lipoxin a4 is a lipid of Fatty Acyls (FA) class. Lipoxin a4 is associated with abnormalities such as Asthma, Cystic Fibrosis, Pneumonia, Obesity and Septicemia. The involved functions are known as Inflammation, Signal, Signal Transduction, Regulation and Metabolic Inhibition. Lipoxin a4 often locates in Immune system, Blood, soluble, Extracellular and Splenic Tissue. The associated genes with Lipoxin A4 are FPR2 gene, Homologous Gene, SAA1 gene, Trp-Lys-Tyr-Met-Val-Met and Annexin 1. The related lipids are Steroids. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Lipoxin A4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Lipoxin A4?

Lipoxin A4 is suspected in Asthma, Cystic Fibrosis, Chagas Cardiomyopathy, Pneumonia, Obesity, Septicemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lipoxin A4

MeSH term MeSH ID Detail
Tuberculosis D014376 20 associated lipids
Stomach Ulcer D013276 75 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Lung Diseases D008171 37 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Colitis D003092 69 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Arthritis D001168 41 associated lipids
Osteitis D010000 10 associated lipids
Substance Withdrawal Syndrome D013375 9 associated lipids
Asthma D001249 52 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Endometriosis D004715 29 associated lipids
Peritonitis D010538 38 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Lipoxin A4

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Lipoxin A4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Lipoxin A4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Lipoxin A4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Lipoxin A4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Lipoxin A4?

Knock-out

Knock-out are used in the study 'Aspirin-triggered 15-epi-lipoxin A4 regulates neutrophil-platelet aggregation and attenuates acute lung injury in mice.' (Ortiz-Muñoz G et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Lipoxin A4

Download all related citations
Per page 10 20 50 100 | Total 639
Authors Title Published Journal PubMed Link
Zong L et al. Lipoxin A4 Attenuates Cell Invasion by Inhibiting ROS/ERK/MMP Pathway in Pancreatic Cancer. 2016 Oxid Med Cell Longev pmid:26649143
Colby JK et al. Lipoxin Signaling in Murine Lung Host Responses to Cryptococcus neoformans Infection. 2016 Am. J. Respir. Cell Mol. Biol. pmid:26039320
Elias I et al. ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance. 2016 Diabetes pmid:27207555
Havixbeck JJ et al. Neutrophil contributions to the induction and regulation of the acute inflammatory response in teleost fish. 2016 J. Leukoc. Biol. pmid:26292979
Pazdrak K et al. Cytokine-Induced Glucocorticoid Resistance from Eosinophil Activation: Protein Phosphatase 5 Modulation of Glucocorticoid Receptor Phosphorylation and Signaling. 2016 J. Immunol. pmid:27742828
Chandrasekharan JA et al. Altering the Anti-inflammatory Lipoxin Microenvironment: a New Insight into Kaposi's Sarcoma-Associated Herpesvirus Pathogenesis. 2016 J. Virol. pmid:27681120
Han X et al. Lipoxin A4 Preconditioning Attenuates Intestinal Ischemia Reperfusion Injury through Keap1/Nrf2 Pathway in a Lipoxin A4 Receptor Independent Manner. 2016 Oxid Med Cell Longev pmid:27375835
Brigatte P et al. Walker 256 Tumor Growth Suppression by Crotoxin Involves Formyl Peptide Receptors and Lipoxin Aâ‚„. 2016 Mediators Inflamm. pmid:27190493
Guo Z et al. Lipoxin A4 Reduces Inflammation Through Formyl Peptide Receptor 2/p38 MAPK Signaling Pathway in Subarachnoid Hemorrhage Rats. 2016 Stroke pmid:26732571
Li L et al. New development in studies of formyl-peptide receptors: critical roles in host defense. 2016 J. Leukoc. Biol. pmid:26701131