Lipoxin A4

Lipoxin a4 is a lipid of Fatty Acyls (FA) class. Lipoxin a4 is associated with abnormalities such as Asthma, Cystic Fibrosis, Pneumonia, Obesity and Septicemia. The involved functions are known as Inflammation, Signal, Signal Transduction, Regulation and Metabolic Inhibition. Lipoxin a4 often locates in Immune system, Blood, soluble, Extracellular and Splenic Tissue. The associated genes with Lipoxin A4 are FPR2 gene, Homologous Gene, SAA1 gene, Trp-Lys-Tyr-Met-Val-Met and Annexin 1. The related lipids are Steroids. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Lipoxin A4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Lipoxin A4?

Lipoxin A4 is suspected in Asthma, Cystic Fibrosis, Chagas Cardiomyopathy, Pneumonia, Obesity, Septicemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lipoxin A4

MeSH term MeSH ID Detail
Toxoplasmosis D014123 9 associated lipids
Eosinophilia D004802 4 associated lipids
Immune Complex Diseases D007105 9 associated lipids
Catalepsy D002375 30 associated lipids
Acute-Phase Reaction D000210 12 associated lipids
Disease Susceptibility D004198 12 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
Uveitis D014605 14 associated lipids
Fetal Growth Retardation D005317 9 associated lipids
Klebsiella Infections D007710 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Lipoxin A4

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Lipoxin A4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Lipoxin A4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Lipoxin A4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Lipoxin A4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Lipoxin A4?

Knock-out

Knock-out are used in the study 'Aspirin-triggered 15-epi-lipoxin A4 regulates neutrophil-platelet aggregation and attenuates acute lung injury in mice.' (Ortiz-Muñoz G et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Lipoxin A4

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Per page 10 20 50 100 | Total 639
Authors Title Published Journal PubMed Link
Ramirez JL et al. A mosquito lipoxin/lipocalin complex mediates innate immune priming in Anopheles gambiae. 2015 Nat Commun pmid:26100162
Börgeson E et al. Lipoxin A4 Attenuates Obesity-Induced Adipose Inflammation and Associated Liver and Kidney Disease. 2015 Cell Metab. pmid:26052006
Campos-Estrada C et al. Simvastatin and Benznidazole-Mediated Prevention of Trypanosoma cruzi-Induced Endothelial Activation: Role of 15-epi-lipoxin A4 in the Action of Simvastatin. 2015 PLoS Negl Trop Dis pmid:25978361
Higgins G et al. Physiological impact of abnormal lipoxin Aâ‚„ production on cystic fibrosis airway epithelium and therapeutic potential. 2015 Biomed Res Int pmid:25866809
Kong X et al. Roles of lipoxin A4 receptor activation and anti-interleukin-1β antibody on the toll-like receptor 2/mycloid differentiation factor 88/nuclear factor-κB pathway in airway inflammation induced by ovalbumin. 2015 Mol Med Rep pmid:25760938
Barnig C and Levy BD Innate immunity is a key factor for the resolution of inflammation in asthma. 2015 Eur Respir Rev pmid:25726564
Wang X et al. Resolution of inflammation is altered in Alzheimer's disease. 2015 Alzheimers Dement pmid:24530025
Zhang C et al. Growth inhibitory effect of polyunsaturated fatty acids (PUFAs) on colon cancer cells via their growth inhibitory metabolites and fatty acid composition changes. 2015 PLoS ONE pmid:25886460
Tateishi N et al. Dietary supplementation with arachidonic acid increases arachidonic acid content in paw, but does not affect arthritis severity or prostaglandin E2 content in rat adjuvant-induced arthritis model. 2015 Lipids Health Dis pmid:25595700
Fahel JS et al. 5-Lipoxygenase negatively regulates Th1 response during Brucella abortus infection in mice. 2015 Infect. Immun. pmid:25583526