Lipoxin A4

Lipoxin a4 is a lipid of Fatty Acyls (FA) class. Lipoxin a4 is associated with abnormalities such as Asthma, Cystic Fibrosis, Pneumonia, Obesity and Septicemia. The involved functions are known as Inflammation, Signal, Signal Transduction, Regulation and Metabolic Inhibition. Lipoxin a4 often locates in Immune system, Blood, soluble, Extracellular and Splenic Tissue. The associated genes with Lipoxin A4 are FPR2 gene, Homologous Gene, SAA1 gene, Trp-Lys-Tyr-Met-Val-Met and Annexin 1. The related lipids are Steroids. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Lipoxin A4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Lipoxin A4?

Lipoxin A4 is suspected in Asthma, Cystic Fibrosis, Chagas Cardiomyopathy, Pneumonia, Obesity, Septicemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lipoxin A4

MeSH term MeSH ID Detail
Gastroenteritis D005759 4 associated lipids
Eosinophilia D004802 4 associated lipids
Tendon Injuries D013708 4 associated lipids
Toxoplasmosis, Animal D014124 5 associated lipids
Peritoneal Diseases D010532 6 associated lipids
Klebsiella Infections D007710 7 associated lipids
Toxoplasmosis D014123 9 associated lipids
Fetal Growth Retardation D005317 9 associated lipids
Substance Withdrawal Syndrome D013375 9 associated lipids
Immune Complex Diseases D007105 9 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Lipoxin A4

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Lipoxin A4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Lipoxin A4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Lipoxin A4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Lipoxin A4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Lipoxin A4?

Knock-out

Knock-out are used in the study 'Aspirin-triggered 15-epi-lipoxin A4 regulates neutrophil-platelet aggregation and attenuates acute lung injury in mice.' (Ortiz-Muñoz G et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Lipoxin A4

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Per page 10 20 50 100 | Total 639
Authors Title Published Journal PubMed Link
Zong L et al. Lipoxin A4 Attenuates Cell Invasion by Inhibiting ROS/ERK/MMP Pathway in Pancreatic Cancer. 2016 Oxid Med Cell Longev pmid:26649143
Havixbeck JJ et al. Neutrophil contributions to the induction and regulation of the acute inflammatory response in teleost fish. 2016 J. Leukoc. Biol. pmid:26292979
Tahan F et al. Increased Postexercise Lipoxin A4 Levels in Exhaled Breath Condensate in Asthmatic Children With Exercise-Induced Bronchoconstriction. 2016 J Investig Allergol Clin Immunol pmid:27012012
Wu B et al. Lipoxin A4 augments host defense in sepsis and reduces Pseudomonas aeruginosa virulence through quorum sensing inhibition. 2016 FASEB J. pmid:26965685
Das UN Inflammatory bowel disease as a disorder of an imbalance between pro- and anti-inflammatory molecules and deficiency of resolution bioactive lipids. 2016 Lipids Health Dis pmid:26762544
Guo Z et al. Lipoxin A4 Reduces Inflammation Through Formyl Peptide Receptor 2/p38 MAPK Signaling Pathway in Subarachnoid Hemorrhage Rats. 2016 Stroke pmid:26732571
Li L et al. New development in studies of formyl-peptide receptors: critical roles in host defense. 2016 J. Leukoc. Biol. pmid:26701131
Börgeson E et al. Lipoxin A4 Attenuates Obesity-Induced Adipose Inflammation and Associated Liver and Kidney Disease. 2015 Cell Metab. pmid:26052006
Campos-Estrada C et al. Simvastatin and Benznidazole-Mediated Prevention of Trypanosoma cruzi-Induced Endothelial Activation: Role of 15-epi-lipoxin A4 in the Action of Simvastatin. 2015 PLoS Negl Trop Dis pmid:25978361
Wang X et al. Resolution of inflammation is altered in Alzheimer's disease. 2015 Alzheimers Dement pmid:24530025