Lipoxin A4

Lipoxin a4 is a lipid of Fatty Acyls (FA) class. Lipoxin a4 is associated with abnormalities such as Asthma, Cystic Fibrosis, Pneumonia, Obesity and Septicemia. The involved functions are known as Inflammation, Signal, Signal Transduction, Regulation and Metabolic Inhibition. Lipoxin a4 often locates in Immune system, Blood, soluble, Extracellular and Splenic Tissue. The associated genes with Lipoxin A4 are FPR2 gene, Homologous Gene, SAA1 gene, Trp-Lys-Tyr-Met-Val-Met and Annexin 1. The related lipids are Steroids. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Lipoxin A4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Lipoxin A4?

Lipoxin A4 is suspected in Asthma, Cystic Fibrosis, Chagas Cardiomyopathy, Pneumonia, Obesity, Septicemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lipoxin A4

MeSH term MeSH ID Detail
Gastroenteritis D005759 4 associated lipids
Eosinophilia D004802 4 associated lipids
Tendon Injuries D013708 4 associated lipids
Toxoplasmosis, Animal D014124 5 associated lipids
Peritoneal Diseases D010532 6 associated lipids
Klebsiella Infections D007710 7 associated lipids
Toxoplasmosis D014123 9 associated lipids
Fetal Growth Retardation D005317 9 associated lipids
Substance Withdrawal Syndrome D013375 9 associated lipids
Immune Complex Diseases D007105 9 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Lipoxin A4

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Lipoxin A4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Lipoxin A4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Lipoxin A4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Lipoxin A4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Lipoxin A4?

Knock-out

Knock-out are used in the study 'Aspirin-triggered 15-epi-lipoxin A4 regulates neutrophil-platelet aggregation and attenuates acute lung injury in mice.' (Ortiz-Muñoz G et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Lipoxin A4

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Per page 10 20 50 100 | Total 639
Authors Title Published Journal PubMed Link
Wenceslau CF et al. Lipoxin A4 mediates aortic contraction via RHOA/RHO kinase, endothelial dysfunction and reactive oxygen species. 2014 J. Vasc. Res. pmid:25612650
Polavarapu S et al. Effect of polyunsaturated fatty acids and their metabolites on bleomycin-induced cytotoxic action on human neuroblastoma cells in vitro. 2014 PLoS ONE pmid:25536345
Kumar R et al. Lipoxin Aâ‚„ prevents the progression of de novo and established endometriosis in a mouse model by attenuating prostaglandin Eâ‚‚ production and estrogen signaling. 2014 PLoS ONE pmid:24587003
Zhao Q et al. LipoxinA4 attenuates myocardial ischemia reperfusion injury via a mechanism related to downregulation of GRP-78 and caspase-12 in rats. 2014 Heart Vessels pmid:24129401
Li C et al. Estradiol and mTORC2 cooperate to enhance prostaglandin biosynthesis and tumorigenesis in TSC2-deficient LAM cells. 2014 J. Exp. Med. pmid:24395886
Ballesteros I et al. Rosiglitazone-induced CD36 up-regulation resolves inflammation by PPARγ and 5-LO-dependent pathways. 2014 J. Leukoc. Biol. pmid:24338629
Eke Gungor H et al. Decreased levels of lipoxin A4 and annexin A1 in wheezy infants. 2014 Int. Arch. Allergy Immunol. pmid:24525704
Osuchowski MF Tender mediation in a ruthless environment: can lipoxins provide lifesaving modifications to fatally deregulated immunoinflammatory responses in sepsis?*. 2014 Crit. Care Med. pmid:24633114
Leo LM et al. Age-dependent relevance of endogenous 5-lipoxygenase derivatives in anxiety-like behavior in mice. 2014 PLoS ONE pmid:24416334
Tateishi N et al. Dietary supplementation of arachidonic acid increases arachidonic acid and lipoxin Aâ‚„ contents in colon, but does not affect severity or prostaglandin Eâ‚‚ content in murine colitis model. 2014 Lipids Health Dis pmid:24507383