Lipoxin A4

Lipoxin a4 is a lipid of Fatty Acyls (FA) class. Lipoxin a4 is associated with abnormalities such as Asthma, Cystic Fibrosis, Pneumonia, Obesity and Septicemia. The involved functions are known as Inflammation, Signal, Signal Transduction, Regulation and Metabolic Inhibition. Lipoxin a4 often locates in Immune system, Blood, soluble, Extracellular and Splenic Tissue. The associated genes with Lipoxin A4 are FPR2 gene, Homologous Gene, SAA1 gene, Trp-Lys-Tyr-Met-Val-Met and Annexin 1. The related lipids are Steroids. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Lipoxin A4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Lipoxin A4?

Lipoxin A4 is suspected in Asthma, Cystic Fibrosis, Chagas Cardiomyopathy, Pneumonia, Obesity, Septicemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lipoxin A4

MeSH term MeSH ID Detail
Tuberculosis D014376 20 associated lipids
Stomach Ulcer D013276 75 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Lung Diseases D008171 37 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Colitis D003092 69 associated lipids
Per page 10 20 50 100 | Total 53

PubChem Associated disorders and diseases

What pathways are associated with Lipoxin A4

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Lipoxin A4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Lipoxin A4?


Related references are published most in these journals:

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What lipids are associated with Lipoxin A4?

Related references are published most in these journals:

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What genes are associated with Lipoxin A4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Lipoxin A4?

Knock-out

Knock-out are used in the study 'Aspirin-triggered 15-epi-lipoxin A4 regulates neutrophil-platelet aggregation and attenuates acute lung injury in mice.' (Ortiz-Muñoz G et al., 2014).

Related references are published most in these journals:

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NCBI Entrez Crosslinks

All references with Lipoxin A4

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Per page 10 20 50 100 | Total 639
Authors Title Published Journal PubMed Link
Zhou CH et al. [Protective effects and possible mechanism of lipoxin A(4) analogue in rats with acute pancreatitis]. 2012 Zhonghua Yi Xue Za Zhi pmid:22781577
Zhao QF et al. [Effects of lipoxinA4 on endoplasmic reticulum stress during myocardial ischemia reperfusion injury in rats]. 2013 Zhonghua Yi Xue Za Zhi pmid:23863683
Yin PL et al. [Reversed changes of the 15-lipoxygenase product lipoxin Aâ‚„ and the 5-lipoxygenase product leukotriene Câ‚„ in children with asthma]. 2010 Zhonghua Jie He He Hu Xi Za Zhi pmid:20979801
Pang HY et al. [Effect of lipoxin A(4) on lipopolysaccharide-induced endothelial hyperpermeability in human umbilical vein endothelial cell]. 2011 Zhonghua Fu Chan Ke Za Zhi pmid:21575454
Liu SJ et al. [Protective effects and its mechanism of lipoxins on human umbilical vein endothelial cells under hypoxia]. 2009 Zhonghua Fu Chan Ke Za Zhi pmid:19570467
Lu C et al. [Transfection of Lipoxin A4 receptor-like protein gene enhanced the inhibitory effect of Lipoxin A4 on human lung fibroblasts proliferation induced by connective tissue growth factor]. 2005 Zhonghua Er Ke Za Zhi pmid:15924723
Liang S et al. [Change of serum myeloperoxidase and lipoxin A4 level in coronary heart disease patients with anxiety and/or depression]. 2013 Zhong Nan Da Xue Xue Bao Yi Xue Ban pmid:23645243
Deng LL et al. [Protective effect of lipoxin A4 against rhabdomyolysis-induced acute kidney injury in rats]. 2012 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi pmid:22980651
Leemans J et al. Prophylactic effects of omega-3 polyunsaturated fatty acids and luteolin on airway hyperresponsiveness and inflammation in cats with experimentally-induced asthma. 2010 Vet. J. pmid:19231257
Lee JY et al. Immune parameters differentiating active from latent tuberculosis infection in humans. 2015 Tuberculosis (Edinb) pmid:26520601