Lipoxin b4

Lipoxin b4 is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 325 references associated with Lipoxin b4 in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Lipoxin b4

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lipoxin b4

MeSH term MeSH ID Detail
Asthma D001249 52 associated lipids
Leukemia, Myelogenous, Chronic, BCR-ABL Positive D015464 17 associated lipids
Nasal Polyps D009298 26 associated lipids
Total 3

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Lipoxin b4

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Authors Title Published Journal PubMed Link
Karra L et al. Lipoxin Bâ‚„ promotes the resolution of allergic inflammation in the upper and lower airways of mice. 2015 Mucosal Immunol pmid:25465102
Fer M et al. Cytochromes P450 from family 4 are the main omega hydroxylating enzymes in humans: CYP4F3B is the prominent player in PUFA metabolism. 2008 J. Lipid Res. pmid:18577768
O'Sullivan TP et al. Aromatic lipoxin A4 and lipoxin B4 analogues display potent biological activities. 2007 J. Med. Chem. pmid:17960922
Parkinson JF Lipoxin and synthetic lipoxin analogs: an overview of anti-inflammatory functions and new concepts in immunomodulation. 2006 Inflamm Allergy Drug Targets pmid:16613568
Harmon SD et al. Oxygenation of omega-3 fatty acids by human cytochrome P450 4F3B: effect on 20-hydroxyeicosatetraenoic acid production. 2006 Prostaglandins Leukot. Essent. Fatty Acids pmid:16820285
Serhan CN Lipoxins and aspirin-triggered 15-epi-lipoxins are the first lipid mediators of endogenous anti-inflammation and resolution. 2005 Sep-Oct Prostaglandins Leukot. Essent. Fatty Acids pmid:16005201
Ariel A et al. Aspirin-triggered lipoxin A4 and B4 analogs block extracellular signal-regulated kinase-dependent TNF-alpha secretion from human T cells. 2003 J. Immunol. pmid:12794159
Goh J et al. Lipoxins: pro-resolution lipid mediators in intestinal inflammation. 2003 Gastroenterology pmid:12671901
Bonnans C et al. Lipoxins are potential endogenous antiinflammatory mediators in asthma. 2002 Am. J. Respir. Crit. Care Med. pmid:12045128
Sontag TJ and Parker RS Cytochrome P450 omega-hydroxylase pathway of tocopherol catabolism. Novel mechanism of regulation of vitamin E status. 2002 J. Biol. Chem. pmid:11997390
McMahon B et al. Lipoxins: revelations on resolution. 2001 Trends Pharmacol. Sci. pmid:11478982
Tornhamre S et al. 15-Lipoxygenation of leukotriene A(4). Studies Of 12- and 15-lipoxygenase efficiency to catalyze lipoxin formation. 2000 Biochim. Biophys. Acta pmid:10760478
Desplat V et al. Effects of lipoxygenase metabolites of arachidonic acid on the growth of human blood CD34(+) progenitors. 2000 Blood Cells Mol. Dis. pmid:11112380
Sanak M et al. Aspirin-tolerant asthmatics generate more lipoxins than aspirin-intolerant asthmatics. 2000 Eur. Respir. J. pmid:10933083
Denizot Y et al. Effect of cytokines and lipid mediators on the synthesis of interleukin 1 beta by human bone marrow stromal cells. 2000 Cytokine pmid:10857767
Kikuta Y et al. Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14. 2000 Arch. Biochem. Biophys. pmid:11185557
Desplat V et al. Incorporation and effect of arachidonic acid on the growth of human myeloma cell lines. 1999 Mediators Inflamm. pmid:10704149
Takano T et al. Neutrophil-mediated changes in vascular permeability are inhibited by topical application of aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogues. 1998 J. Clin. Invest. pmid:9466977
Maddox JF et al. Lipoxin B4 regulates human monocyte/neutrophil adherence and motility: design of stable lipoxin B4 analogs with increased biologic activity. 1998 FASEB J. pmid:9535221
Romano M et al. Activation of human monocytes and the acute monocytic leukemia cell line (THP-1) by lipoxins involves unique signaling pathways for lipoxin A4 versus lipoxin B4: evidence for differential Ca2+ mobilization. 1996 J. Immunol. pmid:8757340