Lipoxin b4

Lipoxin b4 is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 325 references associated with Lipoxin b4 in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Lipoxin b4

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lipoxin b4

MeSH term MeSH ID Detail
Asthma D001249 52 associated lipids
Leukemia, Myelogenous, Chronic, BCR-ABL Positive D015464 17 associated lipids
Nasal Polyps D009298 26 associated lipids
Total 3

PubChem Biomolecular Interactions and Pathways

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All references with Lipoxin b4

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Authors Title Published Journal PubMed Link
pmid:
Brady HR et al. Leukotrienes stimulate neutrophil adhesion to mesangial cells: modulation with lipoxins. 1990 Am. J. Physiol. pmid:2173421
Busija DW et al. Lipoxins A4 and B4 dilate cerebral arterioles of newborn pigs. 1989 Am. J. Physiol. pmid:2916679
Katoh T et al. Renal hemodynamic actions of lipoxins in rats: a comparative physiological study. 1992 Am. J. Physiol. pmid:1415572
Kim SJ Elevated formation of lipoxins in viral antibody-positive rat alveolar macrophages. 1990 Am. J. Respir. Cell Mol. Biol. pmid:2116155
Bonnans C et al. Lipoxins are potential endogenous antiinflammatory mediators in asthma. 2002 Am. J. Respir. Crit. Care Med. pmid:12045128
Borgeat P and Picard S 19-Hydroxyprostaglandin B2 as an internal standard for on-line extraction-high-performance liquid chromatography analysis of lipoxygenase products. 1988 Anal. Biochem. pmid:2841889
Lam BK et al. Phospholipase A2 (PLA2) releases lipoxins and leukotrienes from endogenous sources. 1988 Ann. N. Y. Acad. Sci. pmid:2837961
Kikuta Y et al. Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14. 2000 Arch. Biochem. Biophys. pmid:11185557
Ueda N et al. Lipoxin synthesis by arachidonate 12-lipoxygenase purified from porcine leukocytes. 1987 Biochem. Biophys. Res. Commun. pmid:3122743
Garrick R et al. Transformation of leukotriene A4 to lipoxins by rat kidney mesangial cell. 1989 Biochem. Biophys. Res. Commun. pmid:2547366
Stenke L et al. Formation and proliferative effects of lipoxins in human bone marrow. 1991 Biochem. Biophys. Res. Commun. pmid:1930222
Lam BK et al. A phospholipase A2 isoenzyme provokes lipoxin B formation from endogenous sources of arachidonic acid in porcine leukocytes. 1987 Biochem. Biophys. Res. Commun. pmid:3107549
Palmblad J et al. The effects of lipoxin A and lipoxin B on functional responses of human granulocytes. 1987 Biochem. Biophys. Res. Commun. pmid:3593338
Sok DE et al. Soybean lipoxygenase-catalyzed formation of lipoxin A and lipoxin B isomers from arachidonic acid via 5,15-dihydroperoxyeicosatetraenoic acid. 1988 Biochem. Biophys. Res. Commun. pmid:3132921
Boucher JL et al. Metabolism of lipoxins A4 and B4 and of their all-trans isomers by human leukocytes and rat liver microsomes. 1991 Biochem. Biophys. Res. Commun. pmid:2043100
Romano M et al. Lipoxin synthase activity of human platelet 12-lipoxygenase. 1993 Biochem. J. pmid:8250832
Serhan CN On the relationship between leukotriene and lipoxin production by human neutrophils: evidence for differential metabolism of 15-HETE and 5-HETE. 1989 Biochim. Biophys. Acta pmid:2546590
Nicolaou KC et al. Identification of a novel 7-cis-11-trans-lipoxin A4 generated by human neutrophils: total synthesis, spasmogenic activities and comparison with other geometric isomers of lipoxins A4 and B4. 1989 Biochim. Biophys. Acta pmid:2713393
Brasseur R et al. Conformational analysis of lipoxin A, lipoxin B and their trans-isomers. 1988 Biochim. Biophys. Acta pmid:3365446
Ng CF et al. Agonist-dependent generation of lipoxins from rat basophilic leukemia cell (RBL-1). 1989 Biochim. Biophys. Acta pmid:2503031
Mizukami Y et al. Omega-hydroxylation of lipoxin B4 by human neutrophil microsomes: identification of omega-hydroxy metabolite of lipoxin B4 and catalysis by leukotriene B4 omega-hydroxylase (cytochrome P-450LTB omega). 1993 Biochim. Biophys. Acta pmid:8389204
Edenius C et al. Stimulation of lipoxin synthesis from leukotriene A4 by endogenously formed 12-hydroperoxyeicosatetraenoic acid in activated human platelets. 1994 Biochim. Biophys. Acta pmid:8305492
Tornhamre S et al. 15-Lipoxygenation of leukotriene A(4). Studies Of 12- and 15-lipoxygenase efficiency to catalyze lipoxin formation. 2000 Biochim. Biophys. Acta pmid:10760478
Stenke L et al. Deficient lipoxin synthesis: a novel platelet dysfunction in myeloproliferative disorders with special reference to blastic crisis of chronic myelogenous leukemia. 1991 Blood pmid:1659470
Lerner R et al. Lipoxin A4 induces hyperadhesiveness in human endothelial cells for neutrophils. 1993 Blood pmid:8393356
Desplat V et al. Effects of lipoxygenase metabolites of arachidonic acid on the growth of human blood CD34(+) progenitors. 2000 Blood Cells Mol. Dis. pmid:11112380
Jacques CA et al. The contractile activities of lipoxin A4 and lipoxin B4 for guinea-pig airway tissues. 1988 Br. J. Pharmacol. pmid:2852525
Lee TH et al. Lipoxin A4 and lipoxin B4 inhibit chemotactic responses of human neutrophils stimulated by leukotriene B4 and N-formyl-L-methionyl-L-leucyl-L-phenylalanine. 1989 Clin. Sci. pmid:2548801
Denizot Y et al. Effect of cytokines and lipid mediators on the synthesis of interleukin 1 beta by human bone marrow stromal cells. 2000 Cytokine pmid:10857767
Edenius C et al. On the mechanism of transcellular lipoxin formation in human platelets and granulocytes. 1991 Eur. J. Biochem. pmid:1906402
Kühn H et al. Formation of lipoxin B by the pure reticulocyte lipoxygenase via sequential oxygenation of the substrate. 1987 Eur. J. Biochem. pmid:3121318
Mizukami Y et al. omega-Oxidation of lipoxin B4 by rat liver. Identification of an omega-carboxy metabolite of lipoxin B4. 1994 Eur. J. Biochem. pmid:7925420
Tamaoki J et al. Lipoxin A4 inhibits cholinergic neurotransmission through nitric oxide generation in the rabbit trachea. 1995 Eur. J. Pharmacol. pmid:8991795
Sanak M et al. Aspirin-tolerant asthmatics generate more lipoxins than aspirin-intolerant asthmatics. 2000 Eur. Respir. J. pmid:10933083
Maddox JF et al. Lipoxin B4 regulates human monocyte/neutrophil adherence and motility: design of stable lipoxin B4 analogs with increased biologic activity. 1998 FASEB J. pmid:9535221
Walstra P et al. Evidence for lipoxin formation by bovine polymorphonuclear leukocytes via triple dioxygenation of arachidonic acid. 1988 FEBS Lett. pmid:3125064
Steinhilber D and Roth HJ New series of lipoxins isolated from human eosinophils. 1989 FEBS Lett. pmid:2507350
Edenius C et al. Lipoxin formation in human nasal polyps and bronchial tissue. 1990 FEBS Lett. pmid:2172016
Brezinski ME et al. Lipoxins stimulate prostacyclin generation by human endothelial cells. 1989 FEBS Lett. pmid:2494071
Kühn H et al. Formation of lipoxin B by the pure reticulocyte lipoxygenase. 1986 FEBS Lett. pmid:3096777
Puustinen T et al. Evidence for a 5(6)-epoxytetraene intermediate in the biosynthesis of lipoxins in human leukocytes. Conversion into lipoxin A by cytosolic epoxide hydrolase. 1986 FEBS Lett. pmid:3770188
Feuerstein G and Siren AL Mesenteric vascular responses to i.v. administration of lipoxin A4 and lipoxin B4 in the conscious rat. 1988 FEBS Lett. pmid:3366247
Goh J et al. Lipoxins: pro-resolution lipid mediators in intestinal inflammation. 2003 Gastroenterology pmid:12671901
Uski TK and Högestätt ED Effects of various cyclooxygenase and lipoxygenase metabolites on guinea-pig cerebral arteries. 1992 Gen. Pharmacol. pmid:1592217
Conti P et al. Lipoxins A4 and B4 inhibit leukotriene B4 generation from human neutrophil leukocyte suspensions. 1990 Immunol. Lett. pmid:2167876
Conti P et al. Role of lipoxins A4 and B4 in the generation of arachidonic acid metabolites by rat mast cells and their effect on [3H]serotonin release. 1992 Immunol. Lett. pmid:1612634
Parkinson JF Lipoxin and synthetic lipoxin analogs: an overview of anti-inflammatory functions and new concepts in immunomodulation. 2006 Inflamm Allergy Drug Targets pmid:16613568
Serhan CN and Romano M Lipoxin biosynthesis and actions: role of the human platelet LX-synthase. 1995 J Lipid Mediat Cell Signal pmid:8777573
Pettitt TR et al. Synthesis of lipoxins and other lipoxygenase products by macrophages from the rainbow trout, Oncorhynchus mykiss. 1991 J. Biol. Chem. pmid:1902832