Casticin is a lipid of Polyketides (PK) class. The involved functions are known as Ligand Binding. The related lipids are linoleates.
To understand associated biological information of Casticin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with Casticin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lung Neoplasms | D008175 | 171 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Bronchial Spasm | D001986 | 18 associated lipids |
| Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
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| Elford BC et al. | Potentiation of the antimalarial activity of qinghaosu by methoxylated flavones. | 1987 | Trans. R. Soc. Trop. Med. Hyg. | pmid:3318019 |
| You KM et al. | Vitexicarpin, a flavonoid from the fruits of Vitex rotundifolia, inhibits mouse lymphocyte proliferation and growth of cell lines in vitro. | 1998 | Planta Med. | pmid:9741302 |
| Ono M et al. | New diterpenes and norditerpenes from the fruits of Vitex rotundifolia. | 2002 | J. Nat. Prod. | pmid:11975496 |
| Alam G et al. | Tracheospasmolytic activity of viteosin-A and vitexicarpin isolated from vitex trifolia. | 2002 | Planta Med. | pmid:12451502 |
| DÃaz F et al. | Cytotoxic flavone analogues of vitexicarpin, a constituent of the leaves of Vitex negundo. | 2003 | J. Nat. Prod. | pmid:12828478 |
| Remberg P et al. | Characteristics, clinical effect profile and tolerability of a nasal spray preparation of Artemisia abrotanum L. for allergic rhinitis. | 2004 | Phytomedicine | pmid:14971719 |
| Kobayakawa J et al. | G2-M arrest and antimitotic activity mediated by casticin, a flavonoid isolated from Viticis Fructus (Vitex rotundifolia Linne fil.). | 2004 | Cancer Lett. | pmid:15105046 |
| Wang HY et al. | [Vitexicarpin, a flavonoid from Vitex trifolia L., induces apoptosis in K562 cells via mitochondria-controlled apoptotic pathway]. | 2005 | Yao Xue Xue Bao | pmid:15881322 |
| Olalde Rangel JA et al. | The Systemic Theory of Living Systems. Part IV: Systemic Medicine--The Praxis. | 2005 | Evid Based Complement Alternat Med | pmid:16322799 |
| Haïdara K et al. | The flavonoid Casticin has multiple mechanisms of tumor cytotoxicity action. | 2006 | Cancer Lett. | pmid:16387422 |
| Basalo C et al. | Are extraction methods in quantitative assays of pharmacopoeia monographs exhaustive? A comparison with pressurized liquid extraction. | 2006 | Planta Med. | pmid:16924586 |
| Hu Y et al. | Evaluation of the estrogenic activity of the constituents in the fruits of Vitex rotundifolia L. for the potential treatment of premenstrual syndrome. | 2007 | J. Pharm. Pharmacol. | pmid:17883902 |
| Han X et al. | Isolation of high-purity casticin from Artemisia annua L. by high-speed counter-current chromatography. | 2007 | J Chromatogr A | pmid:17374377 |
| Lin S et al. | In vivo effect of casticin on acute inflammation. | 2007 | Zhong Xi Yi Jie He Xue Bao | pmid:17854563 |
| Hajdú Z et al. | Diterpenoids and flavonoids from the fruits of Vitex agnus-castus and antioxidant activity of the fruit extracts and their constituents. | 2007 | Phytother Res | pmid:17262892 |
| Hu Y et al. | Anti-nociceptive and anti-hyperprolactinemia activities of Fructus Viticis and its effective fractions and chemical constituents. | 2007 | Phytomedicine | pmid:17350238 |
| Androutsopoulos V et al. | Antiproliferative and cytostatic effects of the natural product eupatorin on MDA-MB-468 human breast cancer cells due to CYP1-mediated metabolism. | 2008 | Breast Cancer Res. | pmid:18454852 |
| Shen JK et al. | Casticin induces leukemic cell death through apoptosis and mitotic catastrophe. | 2009 | Ann. Hematol. | pmid:19139893 |