Casticin is a lipid of Polyketides (PK) class. The involved functions are known as Ligand Binding. The related lipids are linoleates.
To understand associated biological information of Casticin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with Casticin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lung Neoplasms | D008175 | 171 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Bronchial Spasm | D001986 | 18 associated lipids |
| Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Webster DE et al. | Opioidergic mechanisms underlying the actions of Vitex agnus-castus L. | 2011 | Biochem. Pharmacol. | pmid:20854795 |
| Koh DJ et al. | Inhibitory effects of casticin on migration of eosinophil and expression of chemokines and adhesion molecules in A549 lung epithelial cells via NF-κB inactivation. | 2011 | J Ethnopharmacol | pmid:21251967 |
| Yang J et al. | Casticin-induced apoptosis involves death receptor 5 upregulation in hepatocellular carcinoma cells. | 2011 | World J. Gastroenterol. | pmid:22090786 |
| Chen D et al. | Induction of apoptosis by casticin in cervical cancer cells through reactive oxygen species-mediated mitochondrial signaling pathways. | 2011 | Oncol. Rep. | pmid:21725610 |
| Barnes EC et al. | Mitchellenes A-E, cyclic sesquiterpenes from the Australian plant Eremophila mitchellii. | 2011 | J. Nat. Prod. | pmid:21877688 |
| Chen SN et al. | Phytoconstituents from Vitex agnus-castus fruits. | 2011 | Fitoterapia | pmid:21163339 |
| Rasoanaivo P et al. | Whole plant extracts versus single compounds for the treatment of malaria: synergy and positive interactions. | 2011 | Malar. J. | pmid:21411015 |
| Freitas S et al. | Flavonoids inhibit angiogenic cytokine production by human glioma cells. | 2011 | Phytother Res | pmid:21170924 |
| Ginsburg H and Deharo E | A call for using natural compounds in the development of new antimalarial treatments - an introduction. | 2011 | Malar. J. | pmid:21411010 |
| YE Q et al. | Casticin, a flavonoid isolated from Vitex rotundifolia, inhibits prolactin release in vivo and in vitro. | 2010 | Acta Pharmacol. Sin. | pmid:21042288 |
| Guan R et al. | [Preparative isolation and purification of the active components from Viticis Fructus by high-speed counter-current chromatography]. | 2010 | Se Pu | pmid:21381420 |
| de Sampaio e Spohr TC et al. | Effects of the flavonoid casticin from Brazilian Croton betulaster in cerebral cortical progenitors in vitro: direct and indirect action through astrocytes. | 2010 | J. Neurosci. Res. | pmid:19746423 |
| Song YC et al. | [Vitexicarpin affects proliferation and apoptosis in mutated p53 breast cancer cell]. | 2010 | Zhonghua Yi Xue Za Zhi | pmid:20450732 |
| Kunwar RM et al. | Traditional herbal medicine in far-west Nepal: a pharmacological appraisal. | 2010 | J Ethnobiol Ethnomed | pmid:21144003 |
| Lewin G et al. | Semisynthesis of natural flavones inhibiting tubulin polymerization, from hesperidin. | 2010 | J. Nat. Prod. | pmid:20356063 |
| Shen JK et al. | Casticin induces leukemic cell death through apoptosis and mitotic catastrophe. | 2009 | Ann. Hematol. | pmid:19139893 |
| Mesaik MA et al. | Isolation and immunomodulatory properties of a flavonoid, casticin from Vitex agnus-castus. | 2009 | Phytother Res | pmid:19441009 |
| Csupor-Löffler B et al. | Antiproliferative effect of flavonoids and sesquiterpenoids from Achillea millefolium s.l. on cultured human tumour cell lines. | 2009 | Phytother Res | pmid:19107850 |
| Choudhary MI et al. | Antiinflammatory and lipoxygenase inhibitory compounds from Vitex agnus-castus. | 2009 | Phytother Res | pmid:19173281 |
| Androutsopoulos V et al. | Antiproliferative and cytostatic effects of the natural product eupatorin on MDA-MB-468 human breast cancer cells due to CYP1-mediated metabolism. | 2008 | Breast Cancer Res. | pmid:18454852 |