5S-HETE

5s-hete is a lipid of Fatty Acyls (FA) class. 5s-hete often locates in Microsomes.

Cross Reference

Introduction

To understand associated biological information of 5S-HETE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 5S-HETE?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 5S-HETE

MeSH term MeSH ID Detail
Arteriosclerosis D001161 86 associated lipids
Bronchial Spasm D001986 18 associated lipids
Coronary Disease D003327 70 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Obstetric Labor, Premature D007752 9 associated lipids
Leukemia D007938 74 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Mastocytosis D008415 5 associated lipids
Familial Mediterranean Fever D010505 12 associated lipids
Pregnancy Complications D011248 19 associated lipids
Per page 10 20 | Total 16

PubChem Associated disorders and diseases

What pathways are associated with 5S-HETE

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 5S-HETE?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 5S-HETE?

There are no associated biomedical information in the current reference collection.

What lipids are associated with 5S-HETE?

There are no associated biomedical information in the current reference collection.

What genes are associated with 5S-HETE?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with 5S-HETE?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 5S-HETE

Download all related citations
Per page 10 20 50 100 | Total 789
Authors Title Published Journal PubMed Link
Walsh SW 5-Hydroxyeicosatetraenoic acid, leukotriene C4, and prostaglandin F2 alpha in amniotic fluid before and during term and preterm labor. 1989 Am. J. Obstet. Gynecol. pmid:2589462
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Bittleman DB and Casale TB 5-Hydroxyeicosatetraenoic acid (HETE)-induced neutrophil transcellular migration is dependent upon enantiomeric structure. 1995 Am. J. Respir. Cell Mol. Biol. pmid:7873191
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Kempen EC et al. Simultaneous quantification of arachidonic acid metabolites in cultured tumor cells using high-performance liquid chromatography/electrospray ionization tandem mass spectrometry. 2001 Anal. Biochem. pmid:11673886
Eskra JD et al. Solid-phase extraction and high-performance liquid chromatography analysis of lipoxygenase pathway products. 1986 Anal. Biochem. pmid:3010774
Boyle T et al. Method for simultaneous isolation and quantitation of platelet activating factor and multiple arachidonate metabolites from small samples: analysis of effects of Staphylococcus aureus enterotoxin B in mice. 1994 Anal. Biochem. pmid:8179192
Wheelan P and Murphy RC Quantitation of 5-lipoxygenase products by electrospray mass spectrometry: effect of ethanol on zymosan-stimulated production of 5-lipoxygenase products by human neutrophils. 1997 Anal. Biochem. pmid:9025916
Graff G et al. Preparation and purification of soybean lipoxygenase-derived unsaturated hydroperoxy and hydroxy fatty acids and determination of molar absorptivities of hydroxy fatty acids. 1990 Anal. Biochem. pmid:2121063
Huwyler J and Gut J Single-step organic extraction of leukotrienes and related compounds and their simultaneous analysis by high-performance liquid chromatography. 1990 Anal. Biochem. pmid:2171381
Henke DC et al. Analysis of leukotrienes, prostaglandins, and other oxygenated metabolites of arachidonic acid by high-performance liquid chromatography. 1984 Anal. Biochem. pmid:6091494
Walsh SW Evidence for 5-hydroxyeicosatetraenoic acid (5-HETE) and leukotriene C4(LTC4) in the onset of labor. 1991 Ann. N. Y. Acad. Sci. pmid:2064194
Chu J and Praticò D 5-lipoxygenase as an endogenous modulator of amyloid β formation in vivo. 2011 Ann. Neurol. pmid:21280074
Parker CW Lipid mediators produced through the lipoxygenase pathway. 1987 Annu. Rev. Immunol. pmid:3036183
Green FA et al. Lipoxygenase products from polymorphonuclear leukocytes and epithelial cells of human saliva. 1987 Arch. Biochem. Biophys. pmid:3116937
Lepley RA and Fitzpatrick FA Inhibition of mitogen-activated protein kinase kinase blocks activation and redistribution of 5-lipoxygenase in HL-60 cells. 1996 Arch. Biochem. Biophys. pmid:8660693
Müller K and Ziereis K Effects of oxygen radicals, hydrogen peroxide and water-soluble singlet oxygen carriers on 5- and 12-lipoxygenase. 1993 Arch. Pharm. (Weinheim) pmid:8267517
Maayah ZH and El-Kadi AO 5-, 12- and 15-Hydroxyeicosatetraenoic acids induce cellular hypertrophy in the human ventricular cardiomyocyte, RL-14 cell line, through MAPK- and NF-κB-dependent mechanism. 2016 Arch. Toxicol. pmid:25600587
Sperling RI et al. Inhibition of leukotriene B4 synthesis in neutrophils from patients with rheumatoid arthritis by a single oral dose of methotrexate. 1990 Arthritis Rheum. pmid:2167685
Nakao J et al. Comparative effect of lipoxygenase products of arachidonic acid on rat aortic smooth muscle cell migration. 1982 Atherosclerosis pmid:6816252
Fujita H et al. Lipoxygenase inhibition decreases neointimal formation following vascular injury. 1999 Atherosclerosis pmid:10525127
Fair A and Pritchard KA Oxidized low density lipoprotein increases U937 cell 5-lipoxygenase activity: induction of 5-lipoxygenase activating protein. 1994 Biochem. Biophys. Res. Commun. pmid:8002971
Wiseman JS and Nichols JS Ketones as electrophilic substrates of lipoxygenase. 1988 Biochem. Biophys. Res. Commun. pmid:3135805
Ding XZ et al. Lipoxygenase inhibitors abolish proliferation of human pancreatic cancer cells. 1999 Biochem. Biophys. Res. Commun. pmid:10405349
Agins AP et al. Detection of a novel cyclooxygenase metabolite produced by human promyelocytic leukemia (HL-60) cells. 1985 Biochem. Biophys. Res. Commun. pmid:2982366
Chapkin RS et al. Ability of 15-hydroxyeicosatrienoic acid (15-OH-20:3) to modulate macrophage arachidonic acid metabolism. 1988 Biochem. Biophys. Res. Commun. pmid:3132920
Wächtershäuser A et al. Expression of 5-lipoxygenase by human colorectal carcinoma Caco-2 cells during butyrate-induced cell differentiation. 2000 Biochem. Biophys. Res. Commun. pmid:10679282
Stenson WF et al. Augmentation of IgE-mediated release of histamine by 5-hydroxyeicosatetraenoic acid and 12-hydroxyeicosatetraenoic acid. 1980 Biochem. Biophys. Res. Commun. pmid:6159889
O'Flaherty JT et al. 5-Oxo-eicosatetraenoate, a potent human neutrophil stimulus. 1993 Biochem. Biophys. Res. Commun. pmid:8386504
Cochran FR and Finch-Arietta MB Optimization of cofactors which regulate RBL-1 arachidonate 5-lipoxygenase. 1989 Biochem. Biophys. Res. Commun. pmid:2742590