| MeSH term | MeSH ID | Detail |
|---|---|---|
| Coronary Disease | D003327 | 70 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Leukemia, Basophilic, Acute | D015471 | 9 associated lipids |
| Gastrointestinal Diseases | D005767 | 20 associated lipids |
| Vomiting | D014839 | 21 associated lipids |
| Leukemia, Experimental | D007942 | 42 associated lipids |
| Bronchial Spasm | D001986 | 18 associated lipids |
| Obstetric Labor, Premature | D007752 | 9 associated lipids |
5S-HETE
5s-hete is a lipid of Fatty Acyls (FA) class. 5s-hete often locates in Microsomes.
Cross Reference
Introduction
To understand associated biological information of 5S-HETE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 5S-HETE
PubChem Associated disorders and diseases
What pathways are associated with 5S-HETE
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 5S-HETE?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
What lipids are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
What genes are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 5S-HETE
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Malo PE | Specific enhancement of LTD4-induced contractions of isolated guinea pig trachea by 5-hydroxyeicosatetraenoic acid (5-HETE). | 1989 | Prostaglandins | pmid:2740525 |
| Serhan CN | On the relationship between leukotriene and lipoxin production by human neutrophils: evidence for differential metabolism of 15-HETE and 5-HETE. | 1989 | Biochim. Biophys. Acta | pmid:2546590 |
| Eskew ML et al. | Effects of inadequate vitamin E and/or selenium nutrition on the release of arachidonic acid metabolites in rat alveolar macrophages. | 1989 | Prostaglandins | pmid:2546191 |
| Hamasaki T et al. | Leukotriene B4 metabolism in neutrophils of patients with chronic granulomatous disease: phorbol myristate acetate decreases endogenous leukotriene B4 via NADPH oxidase-dependent mechanism. | 1989 | Eur. J. Clin. Invest. | pmid:2550242 |
| Bigby TD and Meslier N | Transcellular lipoxygenase metabolism between monocytes and platelets. | 1989 | J. Immunol. | pmid:2550547 |
| Gordon JA et al. | 5-HETE: uptake, distribution, and metabolism in MDCK cells. | 1989 | Am. J. Physiol. | pmid:2492150 |
| Graff G and Anderson LA | 1-[4-[3-[4-[bis(4-fluorophenyl)hydroxymethyl]-1- piperidinyl]propoxy]-3-methoxyphenyl]ethanone(AHR-5333): a selective human blood neutrophil 5-lipoxygenase inhibitor. | 1989 | Prostaglandins | pmid:2554366 |
| Viggiano M et al. | The involvement of oxytocin in ovulation and in the outputs of cyclo-oxygenase and 5-lipoxygenase products from isolated rat ovaries. | 1989 | Prostaglandins | pmid:2501826 |
| Westcott JY et al. | Alveolar transfer and metabolism of eicosanoids in the rat. | 1989 | Am. Rev. Respir. Dis. | pmid:2536256 |
| Nishihira J et al. | Effect of azelastine on leukotriene synthesis in murine peritoneal cells and on thromboxane synthesis in human platelets. | 1989 | Int. Arch. Allergy Appl. Immunol. | pmid:2480337 |
| Romero R et al. | Amniotic fluid concentration of 5-hydroxyeicosatetraenoic acid is increased in human parturition at term. | 1989 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2717653 |
| Cochran FR and Finch-Arietta MB | Optimization of cofactors which regulate RBL-1 arachidonate 5-lipoxygenase. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2742590 |
| Heidel JR et al. | Characterization of arachidonic acid metabolism, superoxide production, and bacterial killing in bovine circulating neutrophils and elicited alveolar neutrophils. | 1989 | J. Leukoc. Biol. | pmid:2543724 |
| Raza H et al. | Specific high affinity binding of lipoxygenase metabolites of arachidonic acid by liver fatty acid binding protein. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2500117 |
| Ku EC et al. | Characterization of CGS 8515 as a selective 5-lipoxygenase inhibitor using in vitro and in vivo models. | 1988 | Biochim. Biophys. Acta | pmid:2833314 |
| Watanabe T et al. | Participation of lipoxygenase products from arachidonic acid in the pathogenesis of cerebral vasospasm. | 1988 | J. Neurochem. | pmid:3126264 |
| Haas TA et al. | Binding of 13-HODE and 5-, 12- and 15-HETE to endothelial cells and subsequent platelet, neutrophil and tumor cell adhesion. | 1988 | Biochim. Biophys. Acta | pmid:3390452 |
| Balsinde J et al. | The interaction of ethanol and exogenous arachidonic acid in the generation of extracellular messengers by mouse peritoneal macrophages. | 1988 | Biochim. Biophys. Acta | pmid:2835991 |
| Bandyopadhyay GK et al. | Proliferative effects of insulin and epidermal growth factor on mouse mammary epithelial cells in primary culture. Enhancement by hydroxyeicosatetraenoic acids and synergism with prostaglandin E2. | 1988 | J. Biol. Chem. | pmid:3286636 |
| Sadler KL and Badwey JA | Second messengers involved in superoxide production by neutrophils. Function and metabolism. | 1988 | Hematol. Oncol. Clin. North Am. | pmid:2839455 |
| Bauldry SA et al. | Phospholipase A2 activation in human neutrophils. Differential actions of diacylglycerols and alkylacylglycerols in priming cells for stimulation by N-formyl-Met-Leu-Phe. | 1988 | J. Biol. Chem. | pmid:2846550 |
| Meghji S et al. | Stimulation of bone resorption by lipoxygenase metabolites of arachidonic acid. | 1988 | Prostaglandins | pmid:2847250 |
| Ueda N and Yamamoto S | The 6R-oxygenase activity of arachidonate 5-lipoxygenase purified from porcine leukocytes. | 1988 | J. Biol. Chem. | pmid:3338999 |
| Shimizu T et al. | Activation of the arachidonate 5-lipoxygenase pathway in the canine basilar artery after experimental subarachnoidal hemorrhage. | 1988 | J. Neurochem. | pmid:2843605 |
| Dahinden CA et al. | Leukotriene production in human neutrophils primed by recombinant human granulocyte/macrophage colony-stimulating factor and stimulated with the complement component C5A and FMLP as second signals. | 1988 | J. Exp. Med. | pmid:2833556 |
| Miyake A et al. | Possible involvement of lipoxygenase pathway of arachidonic acid in rat pituitary hormone release in vitro. | 1988 | J. Endocrinol. Invest. | pmid:2852195 |
| Romero R et al. | Amniotic fluid 5-hydroxyeicosatetraenoic acid in preterm labor. | 1988 | Prostaglandins | pmid:3187060 |
| Rossi AG et al. | Stereospecific bioactions of 5-hydroxyeicosatetraenoate. | 1988 | FEBS Lett. | pmid:3191990 |
| Wiseman JS and Nichols JS | Ketones as electrophilic substrates of lipoxygenase. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3135805 |
| O'Flaherty JT et al. | Mechanism involved in the mobilization of neutrophil calcium by 5-hydroxyeicosatetraenoate. | 1988 | J. Immunol. | pmid:2836511 |
| Moore SA et al. | Murine cerebral microvascular endothelium incorporate and metabolize 12-hydroxyeicosatetraenoic acid. | 1988 | J. Cell. Physiol. | pmid:3170659 |
| Burhop KE et al. | Monohydroxyeicosatetraenoic acids (5-HETE and 15-HETE) induce pulmonary vasoconstriction and edema. | 1988 | Circ. Res. | pmid:3349572 |
| Hwang DH et al. | Dietary linolenic acid and longer-chain n-3 fatty acids: comparison of effects on arachidonic acid metabolism in rats. | 1988 | J. Nutr. | pmid:2895804 |
| Chapkin RS et al. | Ability of 15-hydroxyeicosatrienoic acid (15-OH-20:3) to modulate macrophage arachidonic acid metabolism. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3132920 |
| Arm JP et al. | Enhanced generation of leukotriene B4 by neutrophils stimulated by unopsonized zymosan and by calcium ionophore after exercise-induced asthma. | 1988 | Am. Rev. Respir. Dis. | pmid:2849339 |
| Walenga RW et al. | Formation of hydroxyeicosatetraenoic acids (HETE) in blood from adults versus neonates: reduced production of 12-HETE in cord blood. | 1988 | Pediatr. Res. | pmid:3205606 |
| Shibata N et al. | Augmentation of eicosanoids in ischemic heart muscle in dogs: its role in the deterioration of the ischemic lesion. | 1988 | Jpn. Circ. J. | pmid:3141656 |
| Brown ML et al. | Elevated glucose alters eicosanoid release from porcine aortic endothelial cells. | 1988 | J. Clin. Invest. | pmid:3143746 |
| Warner JA et al. | Effects of a specific inhibitor of the 5-lipoxygenase pathway on mediator release from human basophils and mast cells. | 1988 | J. Pharmacol. Exp. Ther. | pmid:3139865 |
| Badwey JA et al. | Synergistic stimulation of neutrophils. Possible involvement of 5-hydroxy-6,8,11,14-eicosatetraenoate in superoxide release. | 1988 | J. Biol. Chem. | pmid:2830263 |
| Westcott JY et al. | Eicosanoids in human ventricular cerebrospinal fluid following severe brain injury. | 1987 | Prostaglandins | pmid:2835791 |
| O'Flaherty JT and Nishihira J | 5-Hydroxyeicosatetraenoate promotes Ca2+ and protein kinase C mobilization in neutrophils. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3689361 |
| Nigam S | Inhibition of lipoxygenase products by retinoids in human blood cells. | 1987 | Dermatologica | pmid:3691909 |
| Vacas MI et al. | Involvement of 5-lipoxygenase pathway in norepinephrine stimulation of rat pineal melatonin synthesis. | 1987 | Neuroendocrinology | pmid:3431657 |
| Shohami E et al. | Increased thromboxane A2 and 5-HETE production following spinal cord ischemia in the rabbit. | 1987 | Prostaglandins Leukot Med | pmid:3476967 |
| Kimura Y et al. | Effects of an active substance isolated from the roots of Angelica shkiokiana on leukotriene and monohydroxyeicosatetreaenoic acid biosyntheses in human polymorphonuclear leukocytes. | 1987 | Planta Med. | pmid:2832866 |
| Strife RJ et al. | Mass spectrometric analysis of 5-hydroxyeicosatetraenoic acid (5-HETE) in the perfusate of the isolated rat lung. | 1987 | Am. Rev. Respir. Dis. | pmid:3592413 |
| Gut J et al. | Quantification of 5- and 15-HPETE's by direct chemical ionization mass spectrometry. | 1987 | Free Radic. Biol. Med. | pmid:3319797 |
| Takayama H et al. | Preferential incorporation of eicosanoid precursor fatty acids into human umbilical vein endothelial cell phospholipids. | 1987 | Biochim. Biophys. Acta | pmid:2825796 |
| Hatzelmann A and Ullrich V | Regulation of 5-lipoxygenase activity by the glutathione status in human polymorphonuclear leukocytes. | 1987 | Eur. J. Biochem. | pmid:2824200 |