| MeSH term | MeSH ID | Detail |
|---|---|---|
| Mastocytosis | D008415 | 5 associated lipids |
| Carotid Artery Injuries | D020212 | 8 associated lipids |
| Leukemia, Basophilic, Acute | D015471 | 9 associated lipids |
| Obstetric Labor, Premature | D007752 | 9 associated lipids |
| Familial Mediterranean Fever | D010505 | 12 associated lipids |
| Bronchial Spasm | D001986 | 18 associated lipids |
| Pregnancy Complications | D011248 | 19 associated lipids |
| Gastrointestinal Diseases | D005767 | 20 associated lipids |
| Helicobacter Infections | D016481 | 21 associated lipids |
| Vomiting | D014839 | 21 associated lipids |
| Mammary Neoplasms, Animal | D015674 | 27 associated lipids |
| Leukemia, Experimental | D007942 | 42 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
5S-HETE
5s-hete is a lipid of Fatty Acyls (FA) class. 5s-hete often locates in Microsomes.
Cross Reference
Introduction
To understand associated biological information of 5S-HETE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 5S-HETE
PubChem Associated disorders and diseases
What pathways are associated with 5S-HETE
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 5S-HETE?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
What lipids are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
What genes are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 5S-HETE
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid:4294967297 | ||||
| pmid:12898606 | ||||
| pmid:8390010884050023013 | ||||
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| pmid:8450493686380185183 | ||||
| pmid:8389209344365980780 | ||||
| pmid:4916815056725830722 | ||||
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| pmid:651401696553942067 | ||||
| pmid:4049642330557856777 | ||||
| pmid:7226359012646270007 | ||||
| pmid:3543827346140168191 | ||||
| pmid:7094700197005058660 | ||||
| pmid:704 | ||||
| pmid:64 | ||||
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| pmid: | ||||
| Powell WS et al. | Interactions between 5-oxo-ETE and chemokines in stimulating eosinophils. | 2002 | Adv. Exp. Med. Biol. | pmid:12664591 |
| Badwey JA et al. | Products of inflammatory cells synergistically enhance superoxide production by phagocytic leukocytes. | 1991 | Adv. Exp. Med. Biol. | pmid:1667963 |
| Maclouf J et al. | Effects of 12-hydroxy- and 12-hydroperoxy-5,8,10,14-eicosatetraenoic acids on the synthesis of 5-hydroxy-6,8,11,14-eicosatetraenoic acid and leukotriene B4 in human blood leukocytes. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221520 |
| Yamamoto S et al. | Reactions of hydroperoxy-eicosatetraenoic acids with arachidonate 12- and 5-lipoxygenases purified from porcine leukocytes. | 1986 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:2949547 |
| Halpern GM | Anti-inflammatory effects of a stabilized lipid extract of Perna canaliculus (Lyprinol). | 2000 | Allerg Immunol (Paris) | pmid:11094640 |
| Ku EC et al. | Effect of diclofenac sodium on the arachidonic acid cascade. | 1986 | Am. J. Med. | pmid:3085488 |
| Walsh SW | 5-Hydroxyeicosatetraenoic acid, leukotriene C4, and prostaglandin F2 alpha in amniotic fluid before and during term and preterm labor. | 1989 | Am. J. Obstet. Gynecol. | pmid:2589462 |
| Edwin SS et al. | 5-Hydroxyeicosatetraenoic acid biosynthesis by gestational tissues: effects of inflammatory cytokines. | 1993 | Am. J. Obstet. Gynecol. | pmid:8267048 |
| Heidel JR et al. | In vivo chemotaxis of bovine neutrophils induced by 5-lipoxygenase metabolites of arachidonic and eicosapentaenoic acid. | 1989 | Am. J. Pathol. | pmid:2538061 |
| Tanaka N et al. | Comparison of inhibitory actions of indomethacin and epostane on ovulation in rats. | 1991 | Am. J. Physiol. | pmid:1996619 |
| Kruse-Elliott KT and Olson NC | CGS 8515 and indomethacin attenuate cytokine-induced cardiopulmonary dysfunction in pigs. | 1993 | Am. J. Physiol. | pmid:8386479 |
| Hollenberg SM et al. | Eicosanoid production by human aortic endothelial cells in response to endothelin. | 1994 | Am. J. Physiol. | pmid:7810729 |
| Lawson LD and Powell DW | Bradykinin-stimulated eicosanoid synthesis and secretion by rabbit ileal components. | 1987 | Am. J. Physiol. | pmid:2438946 |
| Gordon JA et al. | 5-HETE: uptake, distribution, and metabolism in MDCK cells. | 1989 | Am. J. Physiol. | pmid:2492150 |
| Postoak D et al. | 15-Lipoxygenase products of arachidonate play a role in proliferation of transformed erythroid cells. | 1990 | Am. J. Physiol. | pmid:2124416 |
| Fondacaro JD | Intestinal ion transport and diarrheal disease. | 1986 | Am. J. Physiol. | pmid:2867681 |
| Grimminger F et al. | PAF-induced synthesis of tetraenoic and pentaenoic leukotrienes in the isolated rabbit lung. | 2000 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:10666110 |
| Tavakoli S et al. | Prostaglandin E(2)-induced interleukin-6 release by a human airway epithelial cell line. | 2001 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:11133502 |
| Abe M et al. | Lung cancer cell lines inhibit leukotriene B4 production by human polymorphonuclear leukocytes at the level of phospholipase A2. | 1996 | Am. J. Respir. Cell Mol. Biol. | pmid:8918363 |
| Grimminger F et al. | Synthesis of 4- and 5-series leukotrienes in the lung microvasculature challenged with Escherichia coli hemolysin: critical dependence on exogenous free fatty acid supply. | 1997 | Am. J. Respir. Cell Mol. Biol. | pmid:9070617 |
| Serhan CN | Leukocyte transmigration, chemotaxis, and oxygenated derivatives of arachidonic acid: when is chirality important? | 1995 | Am. J. Respir. Cell Mol. Biol. | pmid:7873189 |
| Bittleman DB and Casale TB | 5-Hydroxyeicosatetraenoic acid (HETE)-induced neutrophil transcellular migration is dependent upon enantiomeric structure. | 1995 | Am. J. Respir. Cell Mol. Biol. | pmid:7873191 |
| Alpert SE and Walenga RW | Human tracheal epithelial cells selectively incorporate 15-hydroxyeicosatetraenoic acid into phosphatidylinositol. | 1993 | Am. J. Respir. Cell Mol. Biol. | pmid:8448017 |
| Marom Z et al. | The effects of corticosteroids on mucous glycoprotein secretion from human airways in vitro. | 1984 | Am. Rev. Respir. Dis. | pmid:6703486 |
| Johnson HG et al. | 15-Hydroxyeicosatetraenoic acid is a potent inflammatory mediator and agonist of canine tracheal mucus secretion. | 1985 | Am. Rev. Respir. Dis. | pmid:3923884 |
| Strife RJ et al. | Mass spectrometric analysis of 5-hydroxyeicosatetraenoic acid (5-HETE) in the perfusate of the isolated rat lung. | 1987 | Am. Rev. Respir. Dis. | pmid:3592413 |
| Arm JP et al. | Enhanced generation of leukotriene B4 by neutrophils stimulated by unopsonized zymosan and by calcium ionophore after exercise-induced asthma. | 1988 | Am. Rev. Respir. Dis. | pmid:2849339 |
| Westcott JY et al. | Alveolar transfer and metabolism of eicosanoids in the rat. | 1989 | Am. Rev. Respir. Dis. | pmid:2536256 |
| Lehmann WD et al. | Quantitative lipoxygenase product profiling by gas chromatography negative-ion chemical ionization mass spectrometry. | 1995 | Anal. Biochem. | pmid:7710076 |
| Leis HJ et al. | Quantitative measurement of 5-, 12-, and 15-hydroxyeicosatetraenoic acid together with 12-hydroxyheptadecatrienoic acid by stable isotope dilution gas chromatography-negative ion chemical ionization-mass spectrometry. | 1987 | Anal. Biochem. | pmid:3300415 |
| Chavis C et al. | A method for the measurement of plasma hydroxyeicosatetraenoic acid levels. | 1999 | Anal. Biochem. | pmid:10361015 |
| Kempen EC et al. | Simultaneous quantification of arachidonic acid metabolites in cultured tumor cells using high-performance liquid chromatography/electrospray ionization tandem mass spectrometry. | 2001 | Anal. Biochem. | pmid:11673886 |
| Eskra JD et al. | Solid-phase extraction and high-performance liquid chromatography analysis of lipoxygenase pathway products. | 1986 | Anal. Biochem. | pmid:3010774 |
| Boyle T et al. | Method for simultaneous isolation and quantitation of platelet activating factor and multiple arachidonate metabolites from small samples: analysis of effects of Staphylococcus aureus enterotoxin B in mice. | 1994 | Anal. Biochem. | pmid:8179192 |
| Wheelan P and Murphy RC | Quantitation of 5-lipoxygenase products by electrospray mass spectrometry: effect of ethanol on zymosan-stimulated production of 5-lipoxygenase products by human neutrophils. | 1997 | Anal. Biochem. | pmid:9025916 |
| Graff G et al. | Preparation and purification of soybean lipoxygenase-derived unsaturated hydroperoxy and hydroxy fatty acids and determination of molar absorptivities of hydroxy fatty acids. | 1990 | Anal. Biochem. | pmid:2121063 |
| Huwyler J and Gut J | Single-step organic extraction of leukotrienes and related compounds and their simultaneous analysis by high-performance liquid chromatography. | 1990 | Anal. Biochem. | pmid:2171381 |
| Henke DC et al. | Analysis of leukotrienes, prostaglandins, and other oxygenated metabolites of arachidonic acid by high-performance liquid chromatography. | 1984 | Anal. Biochem. | pmid:6091494 |
| Walsh SW | Evidence for 5-hydroxyeicosatetraenoic acid (5-HETE) and leukotriene C4(LTC4) in the onset of labor. | 1991 | Ann. N. Y. Acad. Sci. | pmid:2064194 |
| Chu J and Praticò D | 5-lipoxygenase as an endogenous modulator of amyloid β formation in vivo. | 2011 | Ann. Neurol. | pmid:21280074 |
| Parker CW | Lipid mediators produced through the lipoxygenase pathway. | 1987 | Annu. Rev. Immunol. | pmid:3036183 |
| Green FA et al. | Lipoxygenase products from polymorphonuclear leukocytes and epithelial cells of human saliva. | 1987 | Arch. Biochem. Biophys. | pmid:3116937 |
| Lepley RA and Fitzpatrick FA | Inhibition of mitogen-activated protein kinase kinase blocks activation and redistribution of 5-lipoxygenase in HL-60 cells. | 1996 | Arch. Biochem. Biophys. | pmid:8660693 |
| Müller K and Ziereis K | Effects of oxygen radicals, hydrogen peroxide and water-soluble singlet oxygen carriers on 5- and 12-lipoxygenase. | 1993 | Arch. Pharm. (Weinheim) | pmid:8267517 |
| Maayah ZH and El-Kadi AO | 5-, 12- and 15-Hydroxyeicosatetraenoic acids induce cellular hypertrophy in the human ventricular cardiomyocyte, RL-14 cell line, through MAPK- and NF-κB-dependent mechanism. | 2016 | Arch. Toxicol. | pmid:25600587 |
| Sperling RI et al. | Inhibition of leukotriene B4 synthesis in neutrophils from patients with rheumatoid arthritis by a single oral dose of methotrexate. | 1990 | Arthritis Rheum. | pmid:2167685 |
| Nakao J et al. | Comparative effect of lipoxygenase products of arachidonic acid on rat aortic smooth muscle cell migration. | 1982 | Atherosclerosis | pmid:6816252 |
| Fujita H et al. | Lipoxygenase inhibition decreases neointimal formation following vascular injury. | 1999 | Atherosclerosis | pmid:10525127 |
| Fair A and Pritchard KA | Oxidized low density lipoprotein increases U937 cell 5-lipoxygenase activity: induction of 5-lipoxygenase activating protein. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8002971 |
| Jakobsson PJ et al. | Human B lymphocytes possess 5-lipoxygenase activity and convert arachidonic acid to leukotriene B4. | 1991 | Biochem. Biophys. Res. Commun. | pmid:1648910 |
| Salari SH et al. | Inhibition of leukotriene B4 synthesis in human polymorphonuclear leukocytes after exposure to meningococcal lipopolysaccharide. | 1982 | Biochem. Biophys. Res. Commun. | pmid:6280717 |
| Stenson WF et al. | Augmentation of IgE-mediated release of histamine by 5-hydroxyeicosatetraenoic acid and 12-hydroxyeicosatetraenoic acid. | 1980 | Biochem. Biophys. Res. Commun. | pmid:6159889 |
| McColl SR et al. | Modulation by phorbol myristate acetate of arachidonic acid release and leukotriene synthesis by human polymorphonuclear leukocytes stimulated with A23187. | 1986 | Biochem. Biophys. Res. Commun. | pmid:3026382 |
| O'Flaherty JT et al. | Interactions of arachidonate metabolism and protein kinase C in mediating neutrophil function. | 1985 | Biochem. Biophys. Res. Commun. | pmid:2985065 |
| Cochran FR and Finch-Arietta MB | Optimization of cofactors which regulate RBL-1 arachidonate 5-lipoxygenase. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2742590 |
| Bonser RW et al. | Chemotactic peptide stimulated endogenous arachidonic acid metabolism in HL-60 granulocytes. | 1981 | Biochem. Biophys. Res. Commun. | pmid:6797423 |
| Raza H et al. | Specific high affinity binding of lipoxygenase metabolites of arachidonic acid by liver fatty acid binding protein. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2500117 |