| MeSH term | MeSH ID | Detail |
|---|---|---|
| Mastocytosis | D008415 | 5 associated lipids |
| Carotid Artery Injuries | D020212 | 8 associated lipids |
| Leukemia, Basophilic, Acute | D015471 | 9 associated lipids |
| Obstetric Labor, Premature | D007752 | 9 associated lipids |
| Familial Mediterranean Fever | D010505 | 12 associated lipids |
| Bronchial Spasm | D001986 | 18 associated lipids |
| Pregnancy Complications | D011248 | 19 associated lipids |
| Gastrointestinal Diseases | D005767 | 20 associated lipids |
| Helicobacter Infections | D016481 | 21 associated lipids |
| Vomiting | D014839 | 21 associated lipids |
| Mammary Neoplasms, Animal | D015674 | 27 associated lipids |
| Leukemia, Experimental | D007942 | 42 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
5S-HETE
5s-hete is a lipid of Fatty Acyls (FA) class. 5s-hete often locates in Microsomes.
Cross Reference
Introduction
To understand associated biological information of 5S-HETE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 5S-HETE
PubChem Associated disorders and diseases
What pathways are associated with 5S-HETE
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 5S-HETE?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
What lipids are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
What genes are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 5S-HETE
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Moretti RM et al. | Activation of the orphan nuclear receptor RORalpha counteracts the proliferative effect of fatty acids on prostate cancer cells: crucial role of 5-lipoxygenase. | 2004 | Int. J. Cancer | pmid:15305379 |
| David KC et al. | Characterization of the in vitro anti-inflammatory activity of AL-5898 and related benzopyranyl esters and amides. | 2003 | Inflammation | pmid:12772775 |
| Chabannes B et al. | Platelets may inhibit leucotriene biosynthesis by human neutrophils at the integrin level. | 2003 | Br. J. Haematol. | pmid:12694258 |
| Canetti C et al. | Syk activation is a leukotriene B4-regulated event involved in macrophage phagocytosis of IgG-coated targets but not apoptotic cells. | 2003 | Blood | pmid:12730109 |
| Yang P et al. | Inhibition of proliferation of PC3 cells by the branched-chain fatty acid, 12-methyltetradecanoic acid, is associated with inhibition of 5-lipoxygenase. | 2003 | Prostate | pmid:12712407 |
| Brock TG et al. | Prolonged lipopolysaccharide inhibits leukotriene synthesis in peritoneal macrophages: mediation by nitric oxide and prostaglandins. | 2003 | Prostaglandins Other Lipid Mediat. | pmid:14518557 |
| Robinson BS et al. | Inhibition of neutrophil leukotriene B4 production by a novel synthetic N-3 polyunsaturated fatty acid analogue, beta-oxa 21:3n-3. | 2003 | J. Immunol. | pmid:14568954 |
| Wang XJ et al. | Involvement of 5-lipoxygenase metabolites of arachidonic acid in cyclic AMP-stimulated steroidogenesis and steroidogenic acute regulatory protein gene expression. | 2003 | J. Steroid Biochem. Mol. Biol. | pmid:12943700 |
| Jones CE et al. | Expression and characterization of a 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid receptor highly expressed on human eosinophils and neutrophils. | 2003 | Mol. Pharmacol. | pmid:12606753 |
| Rose F et al. | Increased neutrophil mediator release in patients with pulmonary hypertension--suppression by inhaled iloprost. | 2003 | Thromb. Haemost. | pmid:14652649 |
| Beck-Speier I et al. | Sulfur-related air pollutants induce the generation of platelet-activating factor, 5-lipoxygenase- and cyclooxygenase-products in canine alveolar macrophages via activation of phospholipases A2. | 2003 | Prostaglandins Other Lipid Mediat. | pmid:14518563 |
| Chen X et al. | Aberrant arachidonic acid metabolism in esophageal adenocarcinogenesis, and the effects of sulindac, nordihydroguaiaretic acid, and alpha-difluoromethylornithine on tumorigenesis in a rat surgical model. | 2002 | Carcinogenesis | pmid:12507933 |
| Zeng ZZ et al. | 5(S)-hydroxyeicosatetraenoic acid stimulates DNA synthesis in human microvascular endothelial cells via activation of Jak/STAT and phosphatidylinositol 3-kinase/Akt signaling, leading to induction of expression of basic fibroblast growth factor 2. | 2002 | J. Biol. Chem. | pmid:12193593 |
| Tong WG et al. | The mechanisms of lipoxygenase inhibitor-induced apoptosis in human breast cancer cells. | 2002 | Biochem. Biophys. Res. Commun. | pmid:12200139 |
| Hosoi T et al. | Identification of a novel human eicosanoid receptor coupled to G(i/o). | 2002 | J. Biol. Chem. | pmid:12065583 |
| Powell WS et al. | Interactions between 5-oxo-ETE and chemokines in stimulating eosinophils. | 2002 | Adv. Exp. Med. Biol. | pmid:12664591 |
| O'Flaherty JT et al. | 5(S)-Hydroxy-6,8,11,14-E,Z,Z,Z-eicosatetraenoate stimulates PC3 cell signaling and growth by a receptor-dependent mechanism. | 2002 | Cancer Res. | pmid:12460891 |
| Taniguchi H et al. | The lipoxygenase pathways are involved in LH-stimulated progesterone production in bovine corpus luteum. | 2002 | Prostaglandins Other Lipid Mediat. | pmid:11789897 |
| Spanbroek R et al. | IL-4 determines eicosanoid formation in dendritic cells by down-regulation of 5-lipoxygenase and up-regulation of 15-lipoxygenase 1 expression. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11320251 |
| O'Flaherty JT et al. | Protein kinases C translocation responses to low concentrations of arachidonic acid. | 2001 | J. Biol. Chem. | pmid:11328812 |