| MeSH term | MeSH ID | Detail |
|---|---|---|
| Coronary Disease | D003327 | 70 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Leukemia, Basophilic, Acute | D015471 | 9 associated lipids |
| Gastrointestinal Diseases | D005767 | 20 associated lipids |
| Vomiting | D014839 | 21 associated lipids |
| Leukemia, Experimental | D007942 | 42 associated lipids |
| Bronchial Spasm | D001986 | 18 associated lipids |
| Obstetric Labor, Premature | D007752 | 9 associated lipids |
| Familial Mediterranean Fever | D010505 | 12 associated lipids |
| Pregnancy Complications | D011248 | 19 associated lipids |
| Mammary Neoplasms, Animal | D015674 | 27 associated lipids |
| Helicobacter Infections | D016481 | 21 associated lipids |
| Mastocytosis | D008415 | 5 associated lipids |
| Carotid Artery Injuries | D020212 | 8 associated lipids |
5S-HETE
5s-hete is a lipid of Fatty Acyls (FA) class. 5s-hete often locates in Microsomes.
Cross Reference
Introduction
To understand associated biological information of 5S-HETE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 5S-HETE
PubChem Associated disorders and diseases
What pathways are associated with 5S-HETE
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 5S-HETE?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
What lipids are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
What genes are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 5S-HETE
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Powell WS et al. | 5-Oxo-6,8,11,14-eicosatetraenoic acid is a potent stimulator of human eosinophil migration. | 1995 | J. Immunol. | pmid:7706749 |
| Kelefiotis D et al. | Eicosanoid-induced growth and signaling events in rat glomerular mesangial cells. | 1995 | Prostaglandins | pmid:7659782 |
| Bittleman DB and Casale TB | 5-Hydroxyeicosatetraenoic acid (HETE)-induced neutrophil transcellular migration is dependent upon enantiomeric structure. | 1995 | Am. J. Respir. Cell Mol. Biol. | pmid:7873191 |
| Kadri-Hassani N et al. | Bimodal action of fatty acids on PMA-stimulated O2.- production in human adherent monocytes. | 1995 | J Lipid Mediat Cell Signal | pmid:7780683 |
| Motta AB et al. | Role of interferon-alpha in arachidonic acid metabolism by the rat uteri from spayed animals: effect of 17 beta-estradiol. | 1995 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8577780 |
| Fair A and Pritchard KA | Oxidized low density lipoprotein increases U937 cell 5-lipoxygenase activity: induction of 5-lipoxygenase activating protein. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8002971 |
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| Boyle T et al. | Method for simultaneous isolation and quantitation of platelet activating factor and multiple arachidonate metabolites from small samples: analysis of effects of Staphylococcus aureus enterotoxin B in mice. | 1994 | Anal. Biochem. | pmid:8179192 |
| Nishikawa T et al. | Possible involvement of lipoxygenase metabolites of arachidonic acid in the regulation of pregnenolone synthesis in bovine adrenocortical mitochondria. | 1994 | J. Biochem. | pmid:7883758 |
| Powell WS et al. | Phorbol myristate acetate stimulates the formation of 5-oxo-6,8,11,14-eicosatetraenoic acid by human neutrophils by activating NADPH oxidase. | 1994 | J. Biol. Chem. | pmid:7929234 |
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| Gallwitz WE et al. | 5-Lipoxygenase metabolites of arachidonic acid stimulate isolated osteoclasts to resorb calcified matrices. | 1993 | J. Biol. Chem. | pmid:8486677 |
| Marcoz P et al. | Phosphatidic acid stimulates the rolipram-sensitive cyclic nucleotide phosphodiesterase from rat thymocytes. | 1993 | Biochim. Biophys. Acta | pmid:8452869 |
| Kruse-Elliott KT and Olson NC | CGS 8515 and indomethacin attenuate cytokine-induced cardiopulmonary dysfunction in pigs. | 1993 | Am. J. Physiol. | pmid:8386479 |
| Oishi K and Yamaguchi M | Regulatory effect of arachidonic acid on the calcium transport system in rat liver nuclei. | 1993 | Biochem. Pharmacol. | pmid:8385946 |
| Sjolander A et al. | A human epithelial cell line, intestine 407, can produce 5-hydroxyeicosatetraenoic acid and leukotriene B4. | 1993 | Prostaglandins | pmid:8380938 |
| Edwin SS et al. | 5-Hydroxyeicosatetraenoic acid biosynthesis by gestational tissues: effects of inflammatory cytokines. | 1993 | Am. J. Obstet. Gynecol. | pmid:8267048 |
| Winkler JD et al. | Influence of arachidonic acid on indices of phospholipase A2 activity in the human neutrophil. | 1993 | Biochem. J. | pmid:8387780 |
| Sperling RI et al. | Dietary omega-3 polyunsaturated fatty acids inhibit phosphoinositide formation and chemotaxis in neutrophils. | 1993 | J. Clin. Invest. | pmid:8381824 |
| Müller K and Ziereis K | Effects of oxygen radicals, hydrogen peroxide and water-soluble singlet oxygen carriers on 5- and 12-lipoxygenase. | 1993 | Arch. Pharm. (Weinheim) | pmid:8267517 |
| O'Flaherty JT and Rossi AG | 5-hydroxyicosatetraenoate stimulates neutrophils by a stereospecific, G protein-linked mechanism. | 1993 | J. Biol. Chem. | pmid:8392058 |
| O'Flaherty JT et al. | 5-Oxo-eicosatetraenoate, a potent human neutrophil stimulus. | 1993 | Biochem. Biophys. Res. Commun. | pmid:8386504 |
| Radeau T et al. | Effect of nedocromil sodium on sulfidopeptide leukotrienes-stimulated human alveolar macrophages in asthma. | 1993 | Pulm Pharmacol | pmid:8386571 |
| Hatzelmann A et al. | Mode of action of the new selective leukotriene synthesis inhibitor BAY X 1005 ((R)-2-[4-(quinolin-2-yl-methoxy)phenyl]-2-cyclopentyl acetic acid) and structurally related compounds. | 1993 | Biochem. Pharmacol. | pmid:8381000 |
| Gresele P et al. | Cloricromene inhibits leukotriene formation by human polymorphonuclear leucocytes by suppressing arachidonate release from membrane phospholipids. | 1993 | Biochem. Pharmacol. | pmid:8381001 |
| Powell WS et al. | Stimulation of human neutrophils by 5-oxo-6,8,11,14-eicosatetraenoic acid by a mechanism independent of the leukotriene B4 receptor. | 1993 | J. Biol. Chem. | pmid:8387490 |
| Kargman S et al. | Leukotriene synthesis in U937 cells expressing recombinant 5-lipoxygenase. | 1993 | J Lipid Mediat | pmid:8358023 |
| Nihei Y et al. | Epocarbazolins A and B, novel 5-lipoxygenase inhibitors. Taxonomy, fermentation, isolation, structures and biological activities. | 1993 | J. Antibiot. | pmid:8436556 |
| Alpert SE and Walenga RW | Human tracheal epithelial cells selectively incorporate 15-hydroxyeicosatetraenoic acid into phosphatidylinositol. | 1993 | Am. J. Respir. Cell Mol. Biol. | pmid:8448017 |
| Shohami E et al. | The mixed lipoxygenase/cyclooxygenase inhibitor SK&F 105809 reduces cerebral edema after closed head injury in rat. | 1992 Apr-Jun | J Basic Clin Physiol Pharmacol | pmid:1295574 |
| Goya T et al. | Characteristics of alveolar macrophages in experimental septic lung. | 1992 | J. Leukoc. Biol. | pmid:1324290 |
| Köhler T et al. | Phospholipase A2 inhibition by alkylbenzoylacrylic acids. | 1992 | Biochem. Pharmacol. | pmid:1324685 |
| Powell WS et al. | Metabolism of 5(S)-hydroxy-6,8,11,14-eicosatetraenoic acid and other 5(S)-hydroxyeicosanoids by a specific dehydrogenase in human polymorphonuclear leukocytes. | 1992 | J. Biol. Chem. | pmid:1326548 |
| Pueringer RJ et al. | Alveolar macrophages have greater amounts of the enzyme 5-lipoxygenase than do monocytes. | 1992 | J. Appl. Physiol. | pmid:1328141 |
| Dannhardt G and Lehr M | In-vitro evaluation of 5-lipoxygenase and cyclo-oxygenase inhibitors using bovine neutrophils and platelets and HPLC. | 1992 | J. Pharm. Pharmacol. | pmid:1359057 |
| Jacobson PB and Jacobs RS | Fuscoside: an anti-inflammatory marine natural product which selectively inhibits 5-lipoxygenase. Part II: Biochemical studies in the human neutrophil. | 1992 | J. Pharmacol. Exp. Ther. | pmid:1323665 |
| Kawada N et al. | Increased 5-lipoxygenase activity in massive hepatic cell necrosis in the rat correlates with neutrophil infiltration. | 1992 | Hepatology | pmid:1322350 |
| MacNaughton WK et al. | A role for phospholipid-derived inflammatory mediators in intestinal anaphylaxis in the rat. | 1992 | J. Pharmacol. Exp. Ther. | pmid:1738123 |
| Hampson AJ et al. | Biosynthesis of eicosanoids by blood cells of the crab, Carcinus maenas. | 1992 | Biochim. Biophys. Acta | pmid:1543736 |
| Suzuki A et al. | Possible roles of arachidonic acid and its metabolites in induction of tissue plasminogen activator (t-PA) production in human fibroblast, IMR-90 cells by proteose peptone. | 1992 | Biochim. Biophys. Acta | pmid:1731958 |
| Radeau T et al. | Enhanced esterification process of 5-hydroxyeicosatetraenoic acid (5-HETE) in PMN from asthmatic patients. | 1992 | Prostaglandins | pmid:1410523 |
| Smith SR et al. | Actions of a 5-lipoxygenase inhibitor, Sch 40120, on acute inflammatory responses. | 1992 | J. Pharmacol. Exp. Ther. | pmid:1386887 |
| Henricks PA et al. | Pasteurella haemolytica leukotoxin enhances production of leukotriene B4 and 5-hydroxyeicosatetraenoic acid by bovine polymorphonuclear leukocytes. | 1992 | Infect. Immun. | pmid:1322370 |
| van der Donk EM et al. | 12-Lipoxygenase from rat basophilic leukemia cells, an oxygenase with leukotriene A4-synthase activity. | 1992 | Biochim. Biophys. Acta | pmid:1390874 |
| Muller M and Sorrell TC | Leukotriene B4 omega-oxidation by human polymorphonuclear leukocytes is inhibited by pyocyanin, a phenazine derivative produced by Pseudomonas aeruginosa. | 1992 | Infect. Immun. | pmid:1316878 |
| Gukovskaya AS et al. | Effect of the sulfhydryl reagent thimerosal on cytosolic free Ca2+ and membrane potential of thymocytes. | 1992 | Biochim. Biophys. Acta | pmid:1390866 |
| Antoine C et al. | Time-dependent utilization of platelet arachidonic acid by the neutrophil in formation of 5-lipoxygenase products in platelet-neutrophil co-incubations. | 1992 | Biochim. Biophys. Acta | pmid:1329972 |