5S-HETE

5s-hete is a lipid of Fatty Acyls (FA) class. 5s-hete often locates in Microsomes.

Cross Reference

Introduction

To understand associated biological information of 5S-HETE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 5S-HETE?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 5S-HETE

MeSH term MeSH ID Detail
Coronary Disease D003327 70 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Arteriosclerosis D001161 86 associated lipids
Leukemia D007938 74 associated lipids
Leukemia, Basophilic, Acute D015471 9 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Vomiting D014839 21 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Bronchial Spasm D001986 18 associated lipids
Obstetric Labor, Premature D007752 9 associated lipids
Familial Mediterranean Fever D010505 12 associated lipids
Pregnancy Complications D011248 19 associated lipids
Mammary Neoplasms, Animal D015674 27 associated lipids
Helicobacter Infections D016481 21 associated lipids
Mastocytosis D008415 5 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
Per page 10 20 | Total 16

PubChem Associated disorders and diseases

What pathways are associated with 5S-HETE

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 5S-HETE?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 5S-HETE?

There are no associated biomedical information in the current reference collection.

What lipids are associated with 5S-HETE?

There are no associated biomedical information in the current reference collection.

What genes are associated with 5S-HETE?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with 5S-HETE?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 5S-HETE

Download all related citations
Per page 10 20 50 100 | Total 789
Authors Title Published Journal PubMed Link
Bennett PR et al. The effects of lipoxygenase metabolites of arachidonic acid on human myometrial contractility. 1987 Prostaglandins pmid:2823315
Brown ML et al. Ionophore-induced metabolism of phospholipids and eicosanoid production in porcine aortic endothelial cells: selective release of arachidonic acid from diacyl and ether phospholipids. 1987 Biochim. Biophys. Acta pmid:3115300
O'Flaherty JT and Nishihira J 5-Hydroxyeicosatetraenoate promotes Ca2+ and protein kinase C mobilization in neutrophils. 1987 Biochem. Biophys. Res. Commun. pmid:3689361
Nigam S Inhibition of lipoxygenase products by retinoids in human blood cells. 1987 Dermatologica pmid:3691909
Vacas MI et al. Involvement of 5-lipoxygenase pathway in norepinephrine stimulation of rat pineal melatonin synthesis. 1987 Neuroendocrinology pmid:3431657
Shohami E et al. Increased thromboxane A2 and 5-HETE production following spinal cord ischemia in the rabbit. 1987 Prostaglandins Leukot Med pmid:3476967
Strife RJ et al. Mass spectrometric analysis of 5-hydroxyeicosatetraenoic acid (5-HETE) in the perfusate of the isolated rat lung. 1987 Am. Rev. Respir. Dis. pmid:3592413
Gut J et al. Quantification of 5- and 15-HPETE's by direct chemical ionization mass spectrometry. 1987 Free Radic. Biol. Med. pmid:3319797
Leis HJ et al. Quantitative measurement of 5-, 12-, and 15-hydroxyeicosatetraenoic acid together with 12-hydroxyheptadecatrienoic acid by stable isotope dilution gas chromatography-negative ion chemical ionization-mass spectrometry. 1987 Anal. Biochem. pmid:3300415
Lawson LD and Powell DW Bradykinin-stimulated eicosanoid synthesis and secretion by rabbit ileal components. 1987 Am. J. Physiol. pmid:2438946
Littner MR et al. cAMP levels from endogenous and exogenous arachidonic acid in isolated dog lung. 1987 J. Appl. Physiol. pmid:3040660
Taylor SM et al. Arachidonic and eicosapentaenoic acid metabolism in bovine neutrophils and platelets: effect of calcium ionophore. 1987 J. Leukoc. Biol. pmid:3040877
Webb DS and Roth JA Relationship of glucocorticoid suppression of arachidonic acid metabolism to alteration of neutrophil function. 1987 J. Leukoc. Biol. pmid:3027218
McColl SR et al. Modulation of human neutrophil LTA hydrolase activity by phorbol myristate acetate. 1987 Biochem. Biophys. Res. Commun. pmid:2820409
O'Flaherty JT and Nishihira J Arachidonate metabolites, platelet-activating factor, and the mobilization of protein kinase C in human polymorphonuclear neutrophils. 1987 J. Immunol. pmid:3029224
Mobley A et al. Selective inhibition of 5-lipoxygenase pathway in rat pulmonary alveolar macrophages by cigarette smoking. 1987 Biochim. Biophys. Acta pmid:3030439
Yamaoka A et al. Inhibition of leukotriene formation in human leukocytes by halothane. 1987 Biochim. Biophys. Acta pmid:3032266
Gillespie MN et al. Salutary effects of prostaglandin E1 in perfused rat lungs injured with hydrogen peroxide. 1987 J. Pharmacol. Exp. Ther. pmid:3033198
Green FA et al. Monohydroxyeicosatetraenoic acid and leukotriene production by the inflammatory cells of Xenopus laevis. 1987 J. Exp. Zool. pmid:2821155
Skoog MT et al. Glutathione peroxidase is neither required nor kinetically competent for conversion of 5-HPETE to 5-HETE in rat PMN lysates. 1986 Prostaglandins pmid:3086940
Johnson HM et al. Second messenger role of arachidonic acid and its metabolites in interferon-gamma production. 1986 J. Immunol. pmid:2877026
Lewis JG and Adams DO Enhanced release of hydrogen peroxide and metabolites of arachidonic acid by macrophages from SENCAR mice following stimulation with phorbol esters. 1986 Cancer Res. pmid:3019532
O'Flaherty JT et al. Metabolism of 5-hydroxyicosatetraenoate by human neutrophils: production of a novel omega-oxidized derivative. 1986 J. Immunol. pmid:3095426
Shimanuki T et al. A kinetic analysis of peritoneal fluid cytology and arachidonic acid metabolism after abrasion and reabrasion of rabbit peritoneum. 1986 J. Surg. Res. pmid:3463833
Flynn DL et al. Inhibition of 5-hydroxy-eicosatetraenoic acid (5-HETE) formation in intact human neutrophils by naturally-occurring diarylheptanoids: inhibitory activities of curcuminoids and yakuchinones. 1986 Prostaglandins Leukot Med pmid:3460103
Westcott JY et al. Analysis of 6-keto PGF1 alpha, 5-HETE, and LTC4 in rat lung: comparison of GM/MS, RIA, and EIA. 1986 Prostaglandins pmid:3550900
Rhee BG et al. Platelet modulation of polymorphonuclear leukocyte shear induced aggregation. 1986 Blood pmid:3000480
Schafer AI et al. Incorporation of platelet and leukocyte lipoxygenase metabolites by cultured vascular cells. 1986 Blood pmid:3002525
Beetens JR et al. Ketoconazole inhibits the biosynthesis of leukotrienes in vitro and in vivo. 1986 Biochem. Pharmacol. pmid:3006695
Kanaji K et al. Deficient induction of leukotriene synthesis in human neutrophils by lipoxygenase-deficient platelets. 1986 Blood pmid:3006834
Ono N et al. Pharmacological studies on proglumetacin maleate, a new non-steroidal anti-inflammatory drug (4). Mode of action on anti-inflammatory activity. 1986 Jpn. J. Pharmacol. pmid:3102823
Atluru D et al. Arachidonic acid inhibits 5-lipoxygenase in human T cells. 1986 Biochem. Biophys. Res. Commun. pmid:3008733
Nielsen OH et al. Release of leukotriene B4 and 5-hydroxyeicosatetraenoic acid during phagocytosis of artificial immune complexes by peripheral neutrophils in chronic inflammatory bowel disease. 1986 Clin. Exp. Immunol. pmid:3024887
Hadjiagapiou C and Spector AA 12-Hydroxyeicosatetraenoic acid reduces prostacyclin production by endothelial cells. 1986 Prostaglandins pmid:3532204
Eskra JD et al. Solid-phase extraction and high-performance liquid chromatography analysis of lipoxygenase pathway products. 1986 Anal. Biochem. pmid:3010774
Kuhl P et al. Ebselen reduces the formation of LTB4 in human and porcine leukocytes by isomerisation to its 5S, 12R-6-trans-isomer. 1986 Prostaglandins pmid:3020614
Schröder JM Anthralin (1,8-dihydroxyanthrone) is a potent inhibitor of leukotriene production and LTB4-omega oxidation by human neutrophils. 1986 J. Invest. Dermatol. pmid:3021863
Scheffer J et al. Induction of inflammatory mediators from human polymorphonuclear granulocytes and rat mast cells by haemolysin-positive and -negative E. coli strains with different adhesins. 1986 Immunology pmid:2433215
Milvae RA et al. Involvement of lipoxygenase products of arachidonic acid metabolism in bovine luteal function. 1986 Biol. Reprod. pmid:3103701
Pickett WC and Douglas MB NaCN inhibits the stereospecific depletion of LTB4 by guinea pig polymorphonuclear leukocytes. 1986 Prostaglandins pmid:3012651
Skoog MT et al. 5-lipoxygenase from rat PMN lysate. 1986 Prostaglandins pmid:3012653
Erman A et al. Treatment with dexamethasone increases glomerular prostaglandin synthesis in rats. 1986 J. Pharmacol. Exp. Ther. pmid:3093672
McColl SR et al. Modulation by phorbol myristate acetate of arachidonic acid release and leukotriene synthesis by human polymorphonuclear leukocytes stimulated with A23187. 1986 Biochem. Biophys. Res. Commun. pmid:3026382
Laviolette M et al. Decreased leukotriene B4 synthesis in smokers' alveolar macrophages in vitro. 1986 J. Clin. Invest. pmid:3003154
Craven PA and DeRubertis FR Profiles of eicosanoid production by superficial and proliferative colonic epithelial cells and sub-epithelial colonic tissue. 1986 Prostaglandins pmid:3024236
Fondacaro JD Intestinal ion transport and diarrheal disease. 1986 Am. J. Physiol. pmid:2867681
Yamamoto S et al. Reactions of hydroperoxy-eicosatetraenoic acids with arachidonate 12- and 5-lipoxygenases purified from porcine leukocytes. 1986 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2949547
Richards CF et al. Specific incorporation of 5-hydroxy-6,8,11,14-eicosatetraenoic acid into phosphatidylcholine in human endothelial cells. 1986 Biochim. Biophys. Acta pmid:3004591
Ku EC et al. Effect of diclofenac sodium on the arachidonic acid cascade. 1986 Am. J. Med. pmid:3085488
König B et al. Role of Escherichia coli alpha-hemolysin and bacterial adherence in infection: requirement for release of inflammatory mediators from granulocytes and mast cells. 1986 Infect. Immun. pmid:2430890