| MeSH term | MeSH ID | Detail |
|---|---|---|
| Mammary Neoplasms, Animal | D015674 | 27 associated lipids |
| Leukemia, Experimental | D007942 | 42 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
5S-HETE
5s-hete is a lipid of Fatty Acyls (FA) class. 5s-hete often locates in Microsomes.
Cross Reference
Introduction
To understand associated biological information of 5S-HETE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 5S-HETE
PubChem Associated disorders and diseases
What pathways are associated with 5S-HETE
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 5S-HETE?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
What lipids are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
What genes are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 5S-HETE
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Neilson AP et al. | Effect of fish oil on levels of R- and S-enantiomers of 5-, 12-, and 15-hydroxyeicosatetraenoic acids in mouse colonic mucosa. | 2012 | Nutr Cancer | pmid:22149144 |
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| He C et al. | Dynamic eicosanoid responses upon different inhibitor and combination treatments on the arachidonic acid metabolic network. | 2012 | Mol Biosyst | pmid:22446875 |
| Nielsen MS et al. | The effect of low-dose marine n-3 fatty acids on the biosynthesis of pro-inflammatory 5-lipoxygenase pathway metabolites in overweight subjects: a randomized controlled trial. | 2012 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22748976 |
| pmid:2305953396003307568 | ||||
| pmid:2314885530451078767 | ||||
| pmid:2314885531104719475 | ||||
| pmid:2317994000516727363 | ||||
| pmid:2319979654392393522 | ||||
| pmid:2322221562928850286 | ||||
| pmid:2322280056881234804 | ||||
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| pmid:2330984782811580744 | ||||
| pmid:2334379873393405472 | ||||
| pmid:2334386757904331877 | ||||
| pmid:2334393380926139426 | ||||
| pmid:2336630925561969673 | ||||
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| Kang KH et al. | Protection of dopaminergic neurons by 5-lipoxygenase inhibitor. | 2013 | Neuropharmacology | pmid:23800665 |
| pmid:240 | ||||
| Long EK et al. | Fatty acids induce leukotriene C4 synthesis in macrophages in a fatty acid binding protein-dependent manner. | 2013 | Biochim. Biophys. Acta | pmid:24046860 |
| Musch MW et al. | Ionophore-stimulated lipoxygenase activity and histamine release in a cloned murine mast cell, MC9. | 1985 | Prostaglandins | pmid:2408298 |
| Shoam H and Razin E | BW755C inhibits the 5-lipoxygenase in E-mast cells without affecting degranulation. | 1985 | Biochim. Biophys. Acta | pmid:2413896 |
| Meng Z et al. | Inhibitor of 5-lipoxygenase, zileuton, suppresses prostate cancer metastasis by upregulating E-cadherin and paxillin. | 2013 | Urology | pmid:24295266 |
| König B et al. | Role of Escherichia coli alpha-hemolysin and bacterial adherence in infection: requirement for release of inflammatory mediators from granulocytes and mast cells. | 1986 | Infect. Immun. | pmid:2430890 |
| Scheffer J et al. | Induction of inflammatory mediators from human polymorphonuclear granulocytes and rat mast cells by haemolysin-positive and -negative E. coli strains with different adhesins. | 1986 | Immunology | pmid:2433215 |
| Sisignano M et al. | Synthesis of lipid mediators during UVB-induced inflammatory hyperalgesia in rats and mice. | 2013 | PLoS ONE | pmid:24349046 |
| Lawson LD and Powell DW | Bradykinin-stimulated eicosanoid synthesis and secretion by rabbit ileal components. | 1987 | Am. J. Physiol. | pmid:2438946 |
| pmid:24662827 | ||||
| pmid:24746852 | ||||
| Nishihira J et al. | Effect of azelastine on leukotriene synthesis in murine peritoneal cells and on thromboxane synthesis in human platelets. | 1989 | Int. Arch. Allergy Appl. Immunol. | pmid:2480337 |
| Gordon JA et al. | 5-HETE: uptake, distribution, and metabolism in MDCK cells. | 1989 | Am. J. Physiol. | pmid:2492150 |
| Wang J et al. | Stimulation of progesterone and prostaglandin E2 production by lipoxygenase metabolites of arachidonic acid. | 1989 | FEBS Lett. | pmid:2494061 |
| Weitberg AB and Corvese D | Hydroxy- and hydroperoxy-6,8,11,14-eicosatetraenoic acids induce DNA strand breaks in human lymphocytes. | 1989 | Carcinogenesis | pmid:2497998 |
| Raza H et al. | Specific high affinity binding of lipoxygenase metabolites of arachidonic acid by liver fatty acid binding protein. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2500117 |
| Viggiano M et al. | The involvement of oxytocin in ovulation and in the outputs of cyclo-oxygenase and 5-lipoxygenase products from isolated rat ovaries. | 1989 | Prostaglandins | pmid:2501826 |
| Riendeau D et al. | Stimulation of 5-lipoxygenase activity under conditions which promote lipid peroxidation. | 1989 | Biochem. J. | pmid:2512907 |
| Richards CF and Campbell WB | Incorporation of hydroxyeicosatetraenoic acids into cellular lipids of adrenal glomerulosa cells: inhibition of aldosterone release by 5-HETE. | 1989 | Prostaglandins | pmid:2513620 |
| Westcott JY et al. | Alveolar transfer and metabolism of eicosanoids in the rat. | 1989 | Am. Rev. Respir. Dis. | pmid:2536256 |
| Heidel JR et al. | In vivo chemotaxis of bovine neutrophils induced by 5-lipoxygenase metabolites of arachidonic and eicosapentaenoic acid. | 1989 | Am. J. Pathol. | pmid:2538061 |
| Tessner TG et al. | Stimulation of platelet-activating factor synthesis by a nonmetabolizable bioactive analog of platelet-activating factor and influence of arachidonic acid metabolites. | 1989 | J. Biol. Chem. | pmid:2538461 |
| Heidel JR et al. | Characterization of arachidonic acid metabolism, superoxide production, and bacterial killing in bovine circulating neutrophils and elicited alveolar neutrophils. | 1989 | J. Leukoc. Biol. | pmid:2543724 |
| pmid:25449650 | ||||
| Eskew ML et al. | Effects of inadequate vitamin E and/or selenium nutrition on the release of arachidonic acid metabolites in rat alveolar macrophages. | 1989 | Prostaglandins | pmid:2546191 |
| Serhan CN | On the relationship between leukotriene and lipoxin production by human neutrophils: evidence for differential metabolism of 15-HETE and 5-HETE. | 1989 | Biochim. Biophys. Acta | pmid:2546590 |
| Heyworth PG et al. | Protein phosphorylation associated with synergistic stimulation of neutrophils. | 1989 | J. Biol. Chem. | pmid:2549043 |
| Hamasaki T et al. | Leukotriene B4 metabolism in neutrophils of patients with chronic granulomatous disease: phorbol myristate acetate decreases endogenous leukotriene B4 via NADPH oxidase-dependent mechanism. | 1989 | Eur. J. Clin. Invest. | pmid:2550242 |
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| Burstein SH et al. | Antagonism to the actions of platelet activating factor by a nonpsychoactive cannabinoid. | 1989 | J. Pharmacol. Exp. Ther. | pmid:2553925 |
| Graff G and Anderson LA | 1-[4-[3-[4-[bis(4-fluorophenyl)hydroxymethyl]-1- piperidinyl]propoxy]-3-methoxyphenyl]ethanone(AHR-5333): a selective human blood neutrophil 5-lipoxygenase inhibitor. | 1989 | Prostaglandins | pmid:2554366 |