Goya T et al. |
Characteristics of alveolar macrophages in experimental septic lung. |
1992 |
J. Leukoc. Biol. |
pmid:1324290
|
Köhler T et al. |
Phospholipase A2 inhibition by alkylbenzoylacrylic acids. |
1992 |
Biochem. Pharmacol. |
pmid:1324685
|
Pueringer RJ et al. |
Alveolar macrophages have greater amounts of the enzyme 5-lipoxygenase than do monocytes. |
1992 |
J. Appl. Physiol. |
pmid:1328141
|
Jacobson PB and Jacobs RS |
Fuscoside: an anti-inflammatory marine natural product which selectively inhibits 5-lipoxygenase. Part II: Biochemical studies in the human neutrophil. |
1992 |
J. Pharmacol. Exp. Ther. |
pmid:1323665
|
Kawada N et al. |
Increased 5-lipoxygenase activity in massive hepatic cell necrosis in the rat correlates with neutrophil infiltration. |
1992 |
Hepatology |
pmid:1322350
|
van der Donk EM et al. |
12-Lipoxygenase from rat basophilic leukemia cells, an oxygenase with leukotriene A4-synthase activity. |
1992 |
Biochim. Biophys. Acta |
pmid:1390874
|
Shohami E et al. |
The mixed lipoxygenase/cyclooxygenase inhibitor SK&F 105809 reduces cerebral edema after closed head injury in rat. |
1992 Apr-Jun |
J Basic Clin Physiol Pharmacol |
pmid:1295574
|
Gallwitz WE et al. |
5-Lipoxygenase metabolites of arachidonic acid stimulate isolated osteoclasts to resorb calcified matrices. |
1993 |
J. Biol. Chem. |
pmid:8486677
|
Marcoz P et al. |
Phosphatidic acid stimulates the rolipram-sensitive cyclic nucleotide phosphodiesterase from rat thymocytes. |
1993 |
Biochim. Biophys. Acta |
pmid:8452869
|
Kruse-Elliott KT and Olson NC |
CGS 8515 and indomethacin attenuate cytokine-induced cardiopulmonary dysfunction in pigs. |
1993 |
Am. J. Physiol. |
pmid:8386479
|
Oishi K and Yamaguchi M |
Regulatory effect of arachidonic acid on the calcium transport system in rat liver nuclei. |
1993 |
Biochem. Pharmacol. |
pmid:8385946
|
Sjolander A et al. |
A human epithelial cell line, intestine 407, can produce 5-hydroxyeicosatetraenoic acid and leukotriene B4. |
1993 |
Prostaglandins |
pmid:8380938
|
Edwin SS et al. |
5-Hydroxyeicosatetraenoic acid biosynthesis by gestational tissues: effects of inflammatory cytokines. |
1993 |
Am. J. Obstet. Gynecol. |
pmid:8267048
|
Winkler JD et al. |
Influence of arachidonic acid on indices of phospholipase A2 activity in the human neutrophil. |
1993 |
Biochem. J. |
pmid:8387780
|
Sperling RI et al. |
Dietary omega-3 polyunsaturated fatty acids inhibit phosphoinositide formation and chemotaxis in neutrophils. |
1993 |
J. Clin. Invest. |
pmid:8381824
|
Müller K and Ziereis K |
Effects of oxygen radicals, hydrogen peroxide and water-soluble singlet oxygen carriers on 5- and 12-lipoxygenase. |
1993 |
Arch. Pharm. (Weinheim) |
pmid:8267517
|
O'Flaherty JT and Rossi AG |
5-hydroxyicosatetraenoate stimulates neutrophils by a stereospecific, G protein-linked mechanism. |
1993 |
J. Biol. Chem. |
pmid:8392058
|
O'Flaherty JT et al. |
5-Oxo-eicosatetraenoate, a potent human neutrophil stimulus. |
1993 |
Biochem. Biophys. Res. Commun. |
pmid:8386504
|
Radeau T et al. |
Effect of nedocromil sodium on sulfidopeptide leukotrienes-stimulated human alveolar macrophages in asthma. |
1993 |
Pulm Pharmacol |
pmid:8386571
|
Hatzelmann A et al. |
Mode of action of the new selective leukotriene synthesis inhibitor BAY X 1005 ((R)-2-[4-(quinolin-2-yl-methoxy)phenyl]-2-cyclopentyl acetic acid) and structurally related compounds. |
1993 |
Biochem. Pharmacol. |
pmid:8381000
|
Gresele P et al. |
Cloricromene inhibits leukotriene formation by human polymorphonuclear leucocytes by suppressing arachidonate release from membrane phospholipids. |
1993 |
Biochem. Pharmacol. |
pmid:8381001
|
Powell WS et al. |
Stimulation of human neutrophils by 5-oxo-6,8,11,14-eicosatetraenoic acid by a mechanism independent of the leukotriene B4 receptor. |
1993 |
J. Biol. Chem. |
pmid:8387490
|
Kargman S et al. |
Leukotriene synthesis in U937 cells expressing recombinant 5-lipoxygenase. |
1993 |
J Lipid Mediat |
pmid:8358023
|
Nihei Y et al. |
Epocarbazolins A and B, novel 5-lipoxygenase inhibitors. Taxonomy, fermentation, isolation, structures and biological activities. |
1993 |
J. Antibiot. |
pmid:8436556
|
Alpert SE and Walenga RW |
Human tracheal epithelial cells selectively incorporate 15-hydroxyeicosatetraenoic acid into phosphatidylinositol. |
1993 |
Am. J. Respir. Cell Mol. Biol. |
pmid:8448017
|
Fair A and Pritchard KA |
Oxidized low density lipoprotein increases U937 cell 5-lipoxygenase activity: induction of 5-lipoxygenase activating protein. |
1994 |
Biochem. Biophys. Res. Commun. |
pmid:8002971
|
O'Flaherty JT et al. |
Chemical and biological characterization of oxo-eicosatetraenoic acids. |
1994 |
Biochim. Biophys. Acta |
pmid:7803484
|
Hollenberg SM et al. |
Eicosanoid production by human aortic endothelial cells in response to endothelin. |
1994 |
Am. J. Physiol. |
pmid:7810729
|
Lepley RA and Fitzpatrick FA |
Irreversible inactivation of 5-lipoxygenase by leukotriene A4. Characterization of product inactivation with purified enzyme and intact leukocytes. |
1994 |
J. Biol. Chem. |
pmid:8300592
|
Boyle T et al. |
Method for simultaneous isolation and quantitation of platelet activating factor and multiple arachidonate metabolites from small samples: analysis of effects of Staphylococcus aureus enterotoxin B in mice. |
1994 |
Anal. Biochem. |
pmid:8179192
|
Nishikawa T et al. |
Possible involvement of lipoxygenase metabolites of arachidonic acid in the regulation of pregnenolone synthesis in bovine adrenocortical mitochondria. |
1994 |
J. Biochem. |
pmid:7883758
|
Powell WS et al. |
Phorbol myristate acetate stimulates the formation of 5-oxo-6,8,11,14-eicosatetraenoic acid by human neutrophils by activating NADPH oxidase. |
1994 |
J. Biol. Chem. |
pmid:7929234
|
Rosenthal MD and Franson RC |
Separation of agonist-stimulated arachidonate mobilization from subsequent leukotriene B4 synthesis in human neutrophils: different effects of oleoylacetylglycerol and phorbol myristate acetate as priming agents. |
1994 |
J. Cell. Physiol. |
pmid:8077290
|
O'Flaherty JT et al. |
Comparison of 1-O-alkyl-, 1-O-alk-1'-enyl-, and 1-O-acyl-2-acetyl-sn-glycero-3-phosphoethanolamines and -3-phosphocholines as agonists of the platelet-activating factor family. |
1994 |
Biochim. Biophys. Acta |
pmid:8280772
|
Kimura Y et al. |
Effects of stilbenes isolated from medicinal plants on arachidonate metabolism and degranulation in human polymorphonuclear leukocytes. |
1995 |
J Ethnopharmacol |
pmid:7776662
|
Powell WS et al. |
5-Oxo-6,8,11,14-eicosatetraenoic acid is a potent stimulator of human eosinophil migration. |
1995 |
J. Immunol. |
pmid:7706749
|
Lehmann WD et al. |
Quantitative lipoxygenase product profiling by gas chromatography negative-ion chemical ionization mass spectrometry. |
1995 |
Anal. Biochem. |
pmid:7710076
|
Hamasaki Y et al. |
Inhibition of leukotriene production by FK506 in rat basophilic leukemia-1 cells. |
1995 |
Pharmacology |
pmid:7538218
|
Metzger K et al. |
Lipoxygenase products in human saliva: patients with oral cancer compared to controls. |
1995 |
Free Radic. Biol. Med. |
pmid:7744301
|
Kelefiotis D et al. |
Eicosanoid-induced growth and signaling events in rat glomerular mesangial cells. |
1995 |
Prostaglandins |
pmid:7659782
|
Romanelli F et al. |
Arachidonic acid and its metabolites effects on testosterone production by rat Leydig cells. |
1995 |
J. Endocrinol. Invest. |
pmid:7615904
|
Schwenk U and Schröder JM |
5-Oxo-eicosanoids are potent eosinophil chemotactic factors. Functional characterization and structural requirements. |
1995 |
J. Biol. Chem. |
pmid:7797484
|
Serhan CN |
Leukocyte transmigration, chemotaxis, and oxygenated derivatives of arachidonic acid: when is chirality important? |
1995 |
Am. J. Respir. Cell Mol. Biol. |
pmid:7873189
|
Bittleman DB and Casale TB |
5-Hydroxyeicosatetraenoic acid (HETE)-induced neutrophil transcellular migration is dependent upon enantiomeric structure. |
1995 |
Am. J. Respir. Cell Mol. Biol. |
pmid:7873191
|
Kadri-Hassani N et al. |
Bimodal action of fatty acids on PMA-stimulated O2.- production in human adherent monocytes. |
1995 |
J Lipid Mediat Cell Signal |
pmid:7780683
|
Wijkander J et al. |
5-Lipoxygenase products modulate the activity of the 85-kDa phospholipase A2 in human neutrophils. |
1995 |
J. Biol. Chem. |
pmid:7592874
|
Motta AB et al. |
Role of interferon-alpha in arachidonic acid metabolism by the rat uteri from spayed animals: effect of 17 beta-estradiol. |
1995 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:8577780
|
Janssen-Timmen U et al. |
Expression of 5-lipoxygenase in differentiating human skin keratinocytes. |
1995 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7624354
|
Zhang Y et al. |
Synthesis of 5-oxo-6,8,11,14-eicosatetraenoic acid by human monocytes and lymphocytes. |
1996 |
J. Leukoc. Biol. |
pmid:8691070
|
Cleland LG et al. |
Dietary (n-9) eicosatrienoic acid from a cultured fungus inhibits leukotriene B4 synthesis in rats and the effect is modified by dietary linoleic acid. |
1996 |
J. Nutr. |
pmid:8648425
|
Sozzani S et al. |
Stimulating properties of 5-oxo-eicosanoids for human monocytes: synergism with monocyte chemotactic protein-1 and -3. |
1996 |
J. Immunol. |
pmid:8906847
|
Edwin SS et al. |
5-Hydroxyeicosatetraenoic acid and human parturition. |
1996 |
Prostaglandins |
pmid:8873235
|
Lin N et al. |
Increased synthesis of specific eicosanoids in rejected corneal grafts. |
1996 |
Curr. Eye Res. |
pmid:9018436
|
Abe M et al. |
Lung cancer cell lines inhibit leukotriene B4 production by human polymorphonuclear leukocytes at the level of phospholipase A2. |
1996 |
Am. J. Respir. Cell Mol. Biol. |
pmid:8918363
|
Bhatia PA et al. |
5-Lipoxygenase inhibitors: synthesis and structure-activity relationships of a series of 1-aryl-2H,4H-tetrahydro-1,2,4-triazin-3-ones. |
1996 |
J. Med. Chem. |
pmid:8831760
|
Petrich K et al. |
The suppression of 5-lipoxygenation of arachidonic acid in human polymorphonuclear leucocytes by the 15-lipoxygenase product (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid: structure-activity relationship and mechanism of action. |
1996 |
Biochem. J. |
pmid:8615788
|
Lepley RA and Fitzpatrick FA |
Inhibition of mitogen-activated protein kinase kinase blocks activation and redistribution of 5-lipoxygenase in HL-60 cells. |
1996 |
Arch. Biochem. Biophys. |
pmid:8660693
|
Norgauer J et al. |
Chemotactic 5-oxo-icosatetraenoic acids activate a unique pattern of neutrophil responses. Analysis of phospholipid metabolism, intracellular Ca2+ transients, actin reorganization, superoxide-anion production and receptor up-regulation. |
1996 |
Eur. J. Biochem. |
pmid:8665888
|
Nakagawa Y and Ishii E |
Changes in arachidonic acid metabolism and the aggregation of polymorphonuclear leukocytes in rats with streptozotocin-induced diabetes. |
1996 |
Biochim. Biophys. Acta |
pmid:8608172
|
Shraga-Levine Z et al. |
Arachidonic acid and lipoxygenase products stimulate protein kinase C beta mRNA levels in pituitary alpha T3-1 cell line: role in gonadotropin-releasing hormone action. |
1996 |
Biochem. J. |
pmid:8687415
|
Hamer RR et al. |
Dibenzoxepinone hydroxylamines and hydroxamic acids: dual inhibitors of cyclooxygenase and 5-lipoxygenase with potent topical antiinflammatory activity. |
1996 |
J. Med. Chem. |
pmid:8568814
|
Sochanowicz B and Szumiel I |
Arachidonic acid metabolism in murine lymphoma cell sublines differing in radiation sensitivity. |
1996 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:8951992
|
Sun D and Funk CD |
Disruption of 12/15-lipoxygenase expression in peritoneal macrophages. Enhanced utilization of the 5-lipoxygenase pathway and diminished oxidation of low density lipoprotein. |
1996 |
J. Biol. Chem. |
pmid:8798642
|
Ulbricht B et al. |
Differential secretion of cathepsins B and L from normal and tumor human lung cells stimulated by 12(S)-hydroxy-eicosatetraenoic acid. |
1996 |
Exp. Cell Res. |
pmid:8806429
|
Krischer SM et al. |
Protein-facilitated export of arachidonic acid from pig neutrophils. |
1997 |
J. Biol. Chem. |
pmid:9099707
|
Martinsson T et al. |
Effects of ropivacaine on eicosanoid release from human granulocytes and endothelial cells in vitro. |
1997 |
Inflamm. Res. |
pmid:9372311
|
Hada T et al. |
Discovery of 5R-lipoxygenase activity in oocytes of the surf clam, Spisula solidissima. |
1997 |
Biochim. Biophys. Acta |
pmid:9219894
|
Edwin SS et al. |
Action of immunoregulatory agents on 5-HETE production by cultured human amnion cells. |
1997 |
J. Reprod. Immunol. |
pmid:9430742
|
Arai M et al. |
Preferential esterification of endogenously formed 5-hydroxyeicosatetraenoic acid to phospholipids in activated polymorphonuclear leukocytes. |
1997 |
Eur. J. Biochem. |
pmid:9119019
|
Watanabe T et al. |
Ebselen (DR3305) ameliorates delayed cerebral vasospasm in a canine two-hemorrhage model. |
1997 |
Neurol. Res. |
pmid:9329038
|
Carty TJ et al. |
Tenidap inhibits 5-lipoxygenase product formation in vitro, but this activity is not observed in three animal models. |
1997 |
Inflamm. Res. |
pmid:9197987
|
Ghosh J and Myers CE |
Arachidonic acid stimulates prostate cancer cell growth: critical role of 5-lipoxygenase. |
1997 |
Biochem. Biophys. Res. Commun. |
pmid:9199209
|
Tang DG et al. |
Suppression of W256 carcinosarcoma cell apoptosis by arachidonic acid and other polyunsaturated fatty acids. |
1997 |
Int. J. Cancer |
pmid:9378543
|
Foley TD |
5-HPETE is a potent inhibitor of neuronal Na+, K(+)-ATPase activity. |
1997 |
Biochem. Biophys. Res. Commun. |
pmid:9199200
|
Grimminger F et al. |
Synthesis of 4- and 5-series leukotrienes in the lung microvasculature challenged with Escherichia coli hemolysin: critical dependence on exogenous free fatty acid supply. |
1997 |
Am. J. Respir. Cell Mol. Biol. |
pmid:9070617
|
Wheelan P and Murphy RC |
Quantitation of 5-lipoxygenase products by electrospray mass spectrometry: effect of ethanol on zymosan-stimulated production of 5-lipoxygenase products by human neutrophils. |
1997 |
Anal. Biochem. |
pmid:9025916
|
Wen FQ et al. |
Eicosanoid profile in cultured human pulmonary artery smooth muscle cells treated with IL-1 beta and TNF alpha. |
1998 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:9758210
|
Ishihara K et al. |
Inhibition of icosanoid production in MC/9 mouse mast cells by n-3 polyunsaturated fatty acids isolated from edible marine algae. |
1998 |
Biosci. Biotechnol. Biochem. |
pmid:9720225
|
Capodici C et al. |
Integrin-dependent homotypic adhesion of neutrophils. Arachidonic acid activates Raf-1/Mek/Erk via a 5-lipoxygenase- dependent pathway. |
1998 |
J. Clin. Invest. |
pmid:9649570
|
Ghosh J and Myers CE |
Inhibition of arachidonate 5-lipoxygenase triggers massive apoptosis in human prostate cancer cells. |
1998 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:9789062
|
Fiedler J et al. |
Exogenous leukotriene B4 (LTB4) inhibits human neutrophil generation of LTB4 from endogenous arachidonic acid during opsonized zymosan phagocytosis. |
1998 |
J. Pharmacol. Exp. Ther. |
pmid:9765334
|
Hall LM and Murphy RC |
Activation of human polymorphonuclear leukocytes by products derived from the peroxidation of human red blood cell membranes. |
1998 |
Chem. Res. Toxicol. |
pmid:9760276
|
Hall LM and Murphy RC |
Electrospray mass spectrometric analysis of 5-hydroperoxy and 5-hydroxyeicosatetraenoic acids generated by lipid peroxidation of red blood cell ghost phospholipids. |
1998 |
J. Am. Soc. Mass Spectrom. |
pmid:9879367
|
Imai H et al. |
Suppression of leukotriene formation in RBL-2H3 cells that overexpressed phospholipid hydroperoxide glutathione peroxidase. |
1998 |
J. Biol. Chem. |
pmid:9442035
|
Yamazaki R et al. |
Anti-inflammatory effect of YPE-01, a novel diarylheptanoid derivative, on dermal inflammation in mice. |
1998 |
Inflamm. Res. |
pmid:9628261
|
Traianedes K et al. |
5-Lipoxygenase metabolites inhibit bone formation in vitro. |
1998 |
Endocrinology |
pmid:9645691
|
Powell WS et al. |
Biological inactivation of 5-oxo-6,8,11,14-eicosatetraenoic acid by human platelets. |
1999 |
Blood |
pmid:9920859
|
Myers CE and Ghosh J |
Lipoxygenase inhibition in prostate cancer. |
1999 |
Eur. Urol. |
pmid:10325495
|
Chavis C et al. |
A method for the measurement of plasma hydroxyeicosatetraenoic acid levels. |
1999 |
Anal. Biochem. |
pmid:10361015
|
Fujita H et al. |
Lipoxygenase inhibition decreases neointimal formation following vascular injury. |
1999 |
Atherosclerosis |
pmid:10525127
|
Ding XZ et al. |
Lipoxygenase inhibitors abolish proliferation of human pancreatic cancer cells. |
1999 |
Biochem. Biophys. Res. Commun. |
pmid:10405349
|
Dadaian M and Westlund P |
Albumin modifies the metabolism of hydroxyeicosatetraenoic acids via 12-lipoxygenase in human platelets. |
1999 |
J. Lipid Res. |
pmid:10224163
|
Hwang SW et al. |
Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances. |
2000 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:10823958
|
Grimminger F et al. |
PAF-induced synthesis of tetraenoic and pentaenoic leukotrienes in the isolated rabbit lung. |
2000 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:10666110
|
Zimpfer U et al. |
Human dendritic cells are a physiological source of the chemotactic arachidonic acid metabolite 5-oxo-eicosatetraenoic acid. |
2000 |
Inflamm. Res. |
pmid:11131304
|
Franchi A et al. |
[Differential action of non-steroidal antiinflammatory drugs on human gallbladder cyclooxygenase and lipoxygenase]. |
2000 |
Medicina (B Aires) |
pmid:11188896
|
Wächtershäuser A et al. |
Expression of 5-lipoxygenase by human colorectal carcinoma Caco-2 cells during butyrate-induced cell differentiation. |
2000 |
Biochem. Biophys. Res. Commun. |
pmid:10679282
|
Halpern GM |
Anti-inflammatory effects of a stabilized lipid extract of Perna canaliculus (Lyprinol). |
2000 |
Allerg Immunol (Paris) |
pmid:11094640
|
Miller TA et al. |
5-HETE congeners as modulators of cell proliferation. |
2000 |
Bioorg. Med. Chem. Lett. |
pmid:10987416
|
Spanbroek R et al. |
5-lipoxygenase expression in dendritic cells generated from CD34(+) hematopoietic progenitors and in lymphoid organs. |
2000 |
Blood |
pmid:11090070
|