5S-HETE

5s-hete is a lipid of Fatty Acyls (FA) class. 5s-hete often locates in Microsomes.

Cross Reference

Introduction

To understand associated biological information of 5S-HETE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 5S-HETE?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 5S-HETE

MeSH term MeSH ID Detail
Coronary Disease D003327 70 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Arteriosclerosis D001161 86 associated lipids
Leukemia D007938 74 associated lipids
Leukemia, Basophilic, Acute D015471 9 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Vomiting D014839 21 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Bronchial Spasm D001986 18 associated lipids
Obstetric Labor, Premature D007752 9 associated lipids
Per page 10 20 | Total 16

PubChem Associated disorders and diseases

What pathways are associated with 5S-HETE

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 5S-HETE?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 5S-HETE?

There are no associated biomedical information in the current reference collection.

What lipids are associated with 5S-HETE?

There are no associated biomedical information in the current reference collection.

What genes are associated with 5S-HETE?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with 5S-HETE?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 5S-HETE

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Per page 10 20 50 100 | Total 789
Authors Title Published Journal PubMed Link
Giménez-Bastida JA et al. Roles of 5-lipoxygenase and cyclooxygenase-2 in the biosynthesis of hemiketals E2 and D2 by activated human leukocytes. 2017 FASEB J. pmid:28096231
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Dołegowska B et al. Metabolism of eicosanoids and their action on renal function during ischaemia and reperfusion: the effect of alprostadil. 2006 Prostaglandins Leukot. Essent. Fatty Acids pmid:17011760
Hassan S and Carraway RE Involvement of arachidonic acid metabolism and EGF receptor in neurotensin-induced prostate cancer PC3 cell growth. 2006 Regul. Pept. pmid:16330112
Hayashi T et al. Inhibition of 5-lipoxygenase pathway suppresses the growth of bladder cancer cells. 2006 Int. J. Urol. pmid:16903934
Erlemann KR et al. Metabolism of 5-hydroxy-6,8,11,14-eicosatetraenoic acid by human endothelial cells. 2006 Biochem. Biophys. Res. Commun. pmid:16997273
Tommasini I et al. 5-Hydroxyeicosatetraenoic acid is a key intermediate of the arachidonate-dependent protective signaling in monocytes/macrophages exposed to peroxynitrite. 2006 J. Leukoc. Biol. pmid:16885503
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Hosoi T et al. TG1019/OXE, a Galpha(i/o)-protein-coupled receptor, mediates 5-oxo-eicosatetraenoic acid-induced chemotaxis. 2005 Biochem. Biophys. Res. Commun. pmid:16039985
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Kim JH et al. Attenuation of breast tumor cell growth by conjugated linoleic acid via inhibition of 5-lipoxygenase activating protein. 2005 Biochim. Biophys. Acta pmid:16185917
Moretti RM et al. Activation of the orphan nuclear receptor RORalpha counteracts the proliferative effect of fatty acids on prostate cancer cells: crucial role of 5-lipoxygenase. 2004 Int. J. Cancer pmid:15305379
Prasad NS et al. Spice phenolics inhibit human PMNL 5-lipoxygenase. 2004 Prostaglandins Leukot. Essent. Fatty Acids pmid:15120715
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David KC et al. Characterization of the in vitro anti-inflammatory activity of AL-5898 and related benzopyranyl esters and amides. 2003 Inflammation pmid:12772775
Chabannes B et al. Platelets may inhibit leucotriene biosynthesis by human neutrophils at the integrin level. 2003 Br. J. Haematol. pmid:12694258
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Brock TG et al. Prolonged lipopolysaccharide inhibits leukotriene synthesis in peritoneal macrophages: mediation by nitric oxide and prostaglandins. 2003 Prostaglandins Other Lipid Mediat. pmid:14518557
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Powell WS et al. Interactions between 5-oxo-ETE and chemokines in stimulating eosinophils. 2002 Adv. Exp. Med. Biol. pmid:12664591
O'Flaherty JT et al. 5(S)-Hydroxy-6,8,11,14-E,Z,Z,Z-eicosatetraenoate stimulates PC3 cell signaling and growth by a receptor-dependent mechanism. 2002 Cancer Res. pmid:12460891
Taniguchi H et al. The lipoxygenase pathways are involved in LH-stimulated progesterone production in bovine corpus luteum. 2002 Prostaglandins Other Lipid Mediat. pmid:11789897
Tavakoli S et al. Prostaglandin E(2)-induced interleukin-6 release by a human airway epithelial cell line. 2001 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:11133502
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Hevko JM et al. Synthesis of 5-oxo-6,8,11,14-eicosatetraenoic acid and identification of novel omega-oxidized metabolites in the mouse macrophage. 2001 J. Pharmacol. Exp. Ther. pmid:11160610
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Di Girolamo G et al. [Effect of nonsteroidal antiinflammatory drugs on colonic lipoxygenase and cyclooxygenase activities from patients with colonic neoplasia]. 2001 Medicina (B Aires) pmid:11721323
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Avis I et al. Five-lipoxygenase inhibitors can mediate apoptosis in human breast cancer cell lines through complex eicosanoid interactions. 2001 FASEB J. pmid:11511519
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Wegmann M et al. Effect of hydroxyeicosatetraenoic acids on furosemide-sensitive chloride secretion in rat distal colon. 2000 J. Pharmacol. Exp. Ther. pmid:10991970
Spanbroek R et al. 5-lipoxygenase expression in dendritic cells generated from CD34(+) hematopoietic progenitors and in lymphoid organs. 2000 Blood pmid:11090070
Powell WS et al. Biological inactivation of 5-oxo-6,8,11,14-eicosatetraenoic acid by human platelets. 1999 Blood pmid:9920859
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Chavis C et al. A method for the measurement of plasma hydroxyeicosatetraenoic acid levels. 1999 Anal. Biochem. pmid:10361015