| MeSH term | MeSH ID | Detail |
|---|---|---|
| Coronary Disease | D003327 | 70 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Leukemia, Basophilic, Acute | D015471 | 9 associated lipids |
| Gastrointestinal Diseases | D005767 | 20 associated lipids |
| Vomiting | D014839 | 21 associated lipids |
| Leukemia, Experimental | D007942 | 42 associated lipids |
| Bronchial Spasm | D001986 | 18 associated lipids |
| Obstetric Labor, Premature | D007752 | 9 associated lipids |
5S-HETE
5s-hete is a lipid of Fatty Acyls (FA) class. 5s-hete often locates in Microsomes.
Cross Reference
Introduction
To understand associated biological information of 5S-HETE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 5S-HETE
PubChem Associated disorders and diseases
What pathways are associated with 5S-HETE
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 5S-HETE?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
What lipids are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
What genes are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 5S-HETE
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|---|---|---|---|---|
| Giménez-Bastida JA et al. | Roles of 5-lipoxygenase and cyclooxygenase-2 in the biosynthesis of hemiketals E2 and D2 by activated human leukocytes. | 2017 | FASEB J. | pmid:28096231 |
| Maayah ZH and El-Kadi AO | 5-, 12- and 15-Hydroxyeicosatetraenoic acids induce cellular hypertrophy in the human ventricular cardiomyocyte, RL-14 cell line, through MAPK- and NF-κB-dependent mechanism. | 2016 | Arch. Toxicol. | pmid:25600587 |
| Barbour SE et al. | Group VIA Phospholipase A2 (iPLA2β) Modulates Bcl-x 5'-Splice Site Selection and Suppresses Anti-apoptotic Bcl-x(L) in β-Cells. | 2015 | J. Biol. Chem. | pmid:25762722 |
| Allain EP et al. | The Intracellular Localisation and Phosphorylation Profile of the Human 5-Lipoxygenase Δ13 Isoform Differs from That of Its Full Length Counterpart. | 2015 | PLoS ONE | pmid:26173130 |
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| Long EK et al. | Fatty acids induce leukotriene C4 synthesis in macrophages in a fatty acid binding protein-dependent manner. | 2013 | Biochim. Biophys. Acta | pmid:24046860 |
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| Kang KH et al. | Protection of dopaminergic neurons by 5-lipoxygenase inhibitor. | 2013 | Neuropharmacology | pmid:23800665 |
| Meng Z et al. | Inhibitor of 5-lipoxygenase, zileuton, suppresses prostate cancer metastasis by upregulating E-cadherin and paxillin. | 2013 | Urology | pmid:24295266 |
| Sisignano M et al. | Synthesis of lipid mediators during UVB-induced inflammatory hyperalgesia in rats and mice. | 2013 | PLoS ONE | pmid:24349046 |
| Neilson AP et al. | Effect of fish oil on levels of R- and S-enantiomers of 5-, 12-, and 15-hydroxyeicosatetraenoic acids in mouse colonic mucosa. | 2012 | Nutr Cancer | pmid:22149144 |
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| Kim DH et al. | Epoxyeicosatrienoic acid agonist regulates human mesenchymal stem cell-derived adipocytes through activation of HO-1-pAKT signaling and a decrease in PPARγ. | 2010 | Stem Cells Dev. | pmid:20412023 |
| Imaizumi S et al. | L-4F differentially alters plasma levels of oxidized fatty acids resulting in more anti-inflammatory HDL in mice. | 2010 | Drug Metab Lett | pmid:20642447 |
| Niknami M et al. | Decrease in expression or activity of cytosolic phospholipase A2alpha increases cyclooxygenase-1 action: A cross-talk between key enzymes in arachidonic acid pathway in prostate cancer cells. | 2010 | Biochim. Biophys. Acta | pmid:20227521 |
| Liu JY et al. | Inhibition of soluble epoxide hydrolase enhances the anti-inflammatory effects of aspirin and 5-lipoxygenase activation protein inhibitor in a murine model. | 2010 | Biochem. Pharmacol. | pmid:19896470 |
| Jian W et al. | 5-Lipoxygenase-mediated endogenous DNA damage. | 2009 | J. Biol. Chem. | pmid:19390118 |
| Graham FD et al. | Oxidative stress-induced changes in pyridine nucleotides and chemoattractant 5-lipoxygenase products in aging neutrophils. | 2009 | Free Radic. Biol. Med. | pmid:19376220 |
| Khan GN et al. | Pomegranate fruit extract impairs invasion and motility in human breast cancer. | 2009 | Integr Cancer Ther | pmid:19815594 |
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| Cossette C et al. | Human neutrophils convert the sebum-derived polyunsaturated fatty acid Sebaleic acid to a potent granulocyte chemoattractant. | 2008 | J. Biol. Chem. | pmid:18287092 |
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| Gillis RC et al. | Regulation of apoptosis in eicosapentaenoic acid-treated HL-60 cells. | 2007 | J. Surg. Res. | pmid:17084410 |
| Park S et al. | Inhibitory activities and attenuated expressions of 5-LOX with red ginseng in Helicobacter pylori-infected gastric epithelial cells. | 2007 | Dig. Dis. Sci. | pmid:17333352 |
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| Dołegowska B et al. | Metabolism of eicosanoids and their action on renal function during ischaemia and reperfusion: the effect of alprostadil. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:17011760 |
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| Erlemann KR et al. | Metabolism of 5-hydroxy-6,8,11,14-eicosatetraenoic acid by human endothelial cells. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16997273 |
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| Zarini S et al. | Effect of arachidonic acid reacylation on leukotriene biosynthesis in human neutrophils stimulated with granulocyte-macrophage colony-stimulating factor and formyl-methionyl-leucyl-phenylalanine. | 2006 | J. Biol. Chem. | pmid:16495221 |
| Berg C et al. | Platelet-induced growth of human fibroblasts is associated with an increased expression of 5-lipoxygenase. | 2006 | Thromb. Haemost. | pmid:17080223 |
| Shashkin PN et al. | Insulin and glucose play a role in foam cell formation and function. | 2006 | Cardiovasc Diabetol | pmid:16787541 |