| MeSH term | MeSH ID | Detail |
|---|---|---|
| Coronary Disease | D003327 | 70 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Leukemia, Basophilic, Acute | D015471 | 9 associated lipids |
| Gastrointestinal Diseases | D005767 | 20 associated lipids |
| Vomiting | D014839 | 21 associated lipids |
| Leukemia, Experimental | D007942 | 42 associated lipids |
| Bronchial Spasm | D001986 | 18 associated lipids |
| Obstetric Labor, Premature | D007752 | 9 associated lipids |
5S-HETE
5s-hete is a lipid of Fatty Acyls (FA) class. 5s-hete often locates in Microsomes.
Cross Reference
Introduction
To understand associated biological information of 5S-HETE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 5S-HETE
PubChem Associated disorders and diseases
What pathways are associated with 5S-HETE
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 5S-HETE?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
What lipids are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
What genes are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 5S-HETE
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| O'Flaherty JT et al. | 5-Oxo-ETE analogs and the proliferation of cancer cells. | 2005 | Biochim. Biophys. Acta | pmid:16154383 |
| Hosoi T et al. | TG1019/OXE, a Galpha(i/o)-protein-coupled receptor, mediates 5-oxo-eicosatetraenoic acid-induced chemotaxis. | 2005 | Biochem. Biophys. Res. Commun. | pmid:16039985 |
| Kim JH et al. | Conjugated linoleic acid reduction of murine mammary tumor cell growth through 5-hydroxyeicosatetraenoic acid. | 2005 | Biochim. Biophys. Acta | pmid:15708358 |
| Kim JH et al. | Attenuation of breast tumor cell growth by conjugated linoleic acid via inhibition of 5-lipoxygenase activating protein. | 2005 | Biochim. Biophys. Acta | pmid:16185917 |
| Moretti RM et al. | Activation of the orphan nuclear receptor RORalpha counteracts the proliferative effect of fatty acids on prostate cancer cells: crucial role of 5-lipoxygenase. | 2004 | Int. J. Cancer | pmid:15305379 |
| Prasad NS et al. | Spice phenolics inhibit human PMNL 5-lipoxygenase. | 2004 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15120715 |
| Zimmer JS et al. | Fatty acid binding proteins stabilize leukotriene A4: competition with arachidonic acid but not other lipoxygenase products. | 2004 | J. Lipid Res. | pmid:15342681 |
| David KC et al. | Characterization of the in vitro anti-inflammatory activity of AL-5898 and related benzopyranyl esters and amides. | 2003 | Inflammation | pmid:12772775 |
| Chabannes B et al. | Platelets may inhibit leucotriene biosynthesis by human neutrophils at the integrin level. | 2003 | Br. J. Haematol. | pmid:12694258 |
| Canetti C et al. | Syk activation is a leukotriene B4-regulated event involved in macrophage phagocytosis of IgG-coated targets but not apoptotic cells. | 2003 | Blood | pmid:12730109 |
| Yang P et al. | Inhibition of proliferation of PC3 cells by the branched-chain fatty acid, 12-methyltetradecanoic acid, is associated with inhibition of 5-lipoxygenase. | 2003 | Prostate | pmid:12712407 |
| Brock TG et al. | Prolonged lipopolysaccharide inhibits leukotriene synthesis in peritoneal macrophages: mediation by nitric oxide and prostaglandins. | 2003 | Prostaglandins Other Lipid Mediat. | pmid:14518557 |
| Robinson BS et al. | Inhibition of neutrophil leukotriene B4 production by a novel synthetic N-3 polyunsaturated fatty acid analogue, beta-oxa 21:3n-3. | 2003 | J. Immunol. | pmid:14568954 |
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| Jones CE et al. | Expression and characterization of a 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid receptor highly expressed on human eosinophils and neutrophils. | 2003 | Mol. Pharmacol. | pmid:12606753 |
| Rose F et al. | Increased neutrophil mediator release in patients with pulmonary hypertension--suppression by inhaled iloprost. | 2003 | Thromb. Haemost. | pmid:14652649 |
| Beck-Speier I et al. | Sulfur-related air pollutants induce the generation of platelet-activating factor, 5-lipoxygenase- and cyclooxygenase-products in canine alveolar macrophages via activation of phospholipases A2. | 2003 | Prostaglandins Other Lipid Mediat. | pmid:14518563 |
| Chen X et al. | Aberrant arachidonic acid metabolism in esophageal adenocarcinogenesis, and the effects of sulindac, nordihydroguaiaretic acid, and alpha-difluoromethylornithine on tumorigenesis in a rat surgical model. | 2002 | Carcinogenesis | pmid:12507933 |
| Zeng ZZ et al. | 5(S)-hydroxyeicosatetraenoic acid stimulates DNA synthesis in human microvascular endothelial cells via activation of Jak/STAT and phosphatidylinositol 3-kinase/Akt signaling, leading to induction of expression of basic fibroblast growth factor 2. | 2002 | J. Biol. Chem. | pmid:12193593 |
| Tong WG et al. | The mechanisms of lipoxygenase inhibitor-induced apoptosis in human breast cancer cells. | 2002 | Biochem. Biophys. Res. Commun. | pmid:12200139 |
| Hosoi T et al. | Identification of a novel human eicosanoid receptor coupled to G(i/o). | 2002 | J. Biol. Chem. | pmid:12065583 |
| Powell WS et al. | Interactions between 5-oxo-ETE and chemokines in stimulating eosinophils. | 2002 | Adv. Exp. Med. Biol. | pmid:12664591 |
| O'Flaherty JT et al. | 5(S)-Hydroxy-6,8,11,14-E,Z,Z,Z-eicosatetraenoate stimulates PC3 cell signaling and growth by a receptor-dependent mechanism. | 2002 | Cancer Res. | pmid:12460891 |
| Taniguchi H et al. | The lipoxygenase pathways are involved in LH-stimulated progesterone production in bovine corpus luteum. | 2002 | Prostaglandins Other Lipid Mediat. | pmid:11789897 |
| Tavakoli S et al. | Prostaglandin E(2)-induced interleukin-6 release by a human airway epithelial cell line. | 2001 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:11133502 |
| Gupta S et al. | Lipoxygenase-5 is overexpressed in prostate adenocarcinoma. | 2001 | Cancer | pmid:11241241 |
| Hevko JM et al. | Synthesis of 5-oxo-6,8,11,14-eicosatetraenoic acid and identification of novel omega-oxidized metabolites in the mouse macrophage. | 2001 | J. Pharmacol. Exp. Ther. | pmid:11160610 |
| Velardez MO et al. | Role of nitric oxide in the metabolism of arachidonic acid in the rat anterior pituitary gland. | 2001 | Mol. Cell. Endocrinol. | pmid:11165034 |
| Kempen EC et al. | Simultaneous quantification of arachidonic acid metabolites in cultured tumor cells using high-performance liquid chromatography/electrospray ionization tandem mass spectrometry. | 2001 | Anal. Biochem. | pmid:11673886 |
| Di Girolamo G et al. | [Effect of nonsteroidal antiinflammatory drugs on colonic lipoxygenase and cyclooxygenase activities from patients with colonic neoplasia]. | 2001 | Medicina (B Aires) | pmid:11721323 |
| Werz O et al. | p38 MAP kinase mediates stress-induced leukotriene synthesis in a human B-lymphocyte cell line. | 2001 | J. Leukoc. Biol. | pmid:11698504 |
| Avis I et al. | Five-lipoxygenase inhibitors can mediate apoptosis in human breast cancer cell lines through complex eicosanoid interactions. | 2001 | FASEB J. | pmid:11511519 |
| Spanbroek R et al. | IL-4 determines eicosanoid formation in dendritic cells by down-regulation of 5-lipoxygenase and up-regulation of 15-lipoxygenase 1 expression. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11320251 |
| O'Flaherty JT et al. | Protein kinases C translocation responses to low concentrations of arachidonic acid. | 2001 | J. Biol. Chem. | pmid:11328812 |
| Hwang SW et al. | Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10823958 |
| Grimminger F et al. | PAF-induced synthesis of tetraenoic and pentaenoic leukotrienes in the isolated rabbit lung. | 2000 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:10666110 |
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| Franchi A et al. | [Differential action of non-steroidal antiinflammatory drugs on human gallbladder cyclooxygenase and lipoxygenase]. | 2000 | Medicina (B Aires) | pmid:11188896 |
| Wächtershäuser A et al. | Expression of 5-lipoxygenase by human colorectal carcinoma Caco-2 cells during butyrate-induced cell differentiation. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10679282 |
| Halpern GM | Anti-inflammatory effects of a stabilized lipid extract of Perna canaliculus (Lyprinol). | 2000 | Allerg Immunol (Paris) | pmid:11094640 |
| Miller TA et al. | 5-HETE congeners as modulators of cell proliferation. | 2000 | Bioorg. Med. Chem. Lett. | pmid:10987416 |
| Wegmann M et al. | Effect of hydroxyeicosatetraenoic acids on furosemide-sensitive chloride secretion in rat distal colon. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10991970 |
| Spanbroek R et al. | 5-lipoxygenase expression in dendritic cells generated from CD34(+) hematopoietic progenitors and in lymphoid organs. | 2000 | Blood | pmid:11090070 |
| Powell WS et al. | Biological inactivation of 5-oxo-6,8,11,14-eicosatetraenoic acid by human platelets. | 1999 | Blood | pmid:9920859 |
| Myers CE and Ghosh J | Lipoxygenase inhibition in prostate cancer. | 1999 | Eur. Urol. | pmid:10325495 |
| Ding XZ et al. | Lipoxygenase inhibitors abolish proliferation of human pancreatic cancer cells. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10405349 |