| MeSH term | MeSH ID | Detail |
|---|---|---|
| Coronary Disease | D003327 | 70 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Leukemia, Basophilic, Acute | D015471 | 9 associated lipids |
| Gastrointestinal Diseases | D005767 | 20 associated lipids |
| Vomiting | D014839 | 21 associated lipids |
| Leukemia, Experimental | D007942 | 42 associated lipids |
| Bronchial Spasm | D001986 | 18 associated lipids |
| Obstetric Labor, Premature | D007752 | 9 associated lipids |
5S-HETE
5s-hete is a lipid of Fatty Acyls (FA) class. 5s-hete often locates in Microsomes.
Cross Reference
Introduction
To understand associated biological information of 5S-HETE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 5S-HETE
PubChem Associated disorders and diseases
What pathways are associated with 5S-HETE
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 5S-HETE?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
What lipids are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
What genes are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with 5S-HETE?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 5S-HETE
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chavis C et al. | A method for the measurement of plasma hydroxyeicosatetraenoic acid levels. | 1999 | Anal. Biochem. | pmid:10361015 |
| Fujita H et al. | Lipoxygenase inhibition decreases neointimal formation following vascular injury. | 1999 | Atherosclerosis | pmid:10525127 |
| Dadaian M and Westlund P | Albumin modifies the metabolism of hydroxyeicosatetraenoic acids via 12-lipoxygenase in human platelets. | 1999 | J. Lipid Res. | pmid:10224163 |
| Wen FQ et al. | Eicosanoid profile in cultured human pulmonary artery smooth muscle cells treated with IL-1 beta and TNF alpha. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9758210 |
| Ishihara K et al. | Inhibition of icosanoid production in MC/9 mouse mast cells by n-3 polyunsaturated fatty acids isolated from edible marine algae. | 1998 | Biosci. Biotechnol. Biochem. | pmid:9720225 |
| Capodici C et al. | Integrin-dependent homotypic adhesion of neutrophils. Arachidonic acid activates Raf-1/Mek/Erk via a 5-lipoxygenase- dependent pathway. | 1998 | J. Clin. Invest. | pmid:9649570 |
| Ghosh J and Myers CE | Inhibition of arachidonate 5-lipoxygenase triggers massive apoptosis in human prostate cancer cells. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9789062 |
| Fiedler J et al. | Exogenous leukotriene B4 (LTB4) inhibits human neutrophil generation of LTB4 from endogenous arachidonic acid during opsonized zymosan phagocytosis. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9765334 |
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| Hall LM and Murphy RC | Electrospray mass spectrometric analysis of 5-hydroperoxy and 5-hydroxyeicosatetraenoic acids generated by lipid peroxidation of red blood cell ghost phospholipids. | 1998 | J. Am. Soc. Mass Spectrom. | pmid:9879367 |
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| Yamazaki R et al. | Anti-inflammatory effect of YPE-01, a novel diarylheptanoid derivative, on dermal inflammation in mice. | 1998 | Inflamm. Res. | pmid:9628261 |
| Traianedes K et al. | 5-Lipoxygenase metabolites inhibit bone formation in vitro. | 1998 | Endocrinology | pmid:9645691 |
| Krischer SM et al. | Protein-facilitated export of arachidonic acid from pig neutrophils. | 1997 | J. Biol. Chem. | pmid:9099707 |
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| Hada T et al. | Discovery of 5R-lipoxygenase activity in oocytes of the surf clam, Spisula solidissima. | 1997 | Biochim. Biophys. Acta | pmid:9219894 |
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| Watanabe T et al. | Ebselen (DR3305) ameliorates delayed cerebral vasospasm in a canine two-hemorrhage model. | 1997 | Neurol. Res. | pmid:9329038 |
| Carty TJ et al. | Tenidap inhibits 5-lipoxygenase product formation in vitro, but this activity is not observed in three animal models. | 1997 | Inflamm. Res. | pmid:9197987 |
| Ghosh J and Myers CE | Arachidonic acid stimulates prostate cancer cell growth: critical role of 5-lipoxygenase. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9199209 |
| Tang DG et al. | Suppression of W256 carcinosarcoma cell apoptosis by arachidonic acid and other polyunsaturated fatty acids. | 1997 | Int. J. Cancer | pmid:9378543 |
| Foley TD | 5-HPETE is a potent inhibitor of neuronal Na+, K(+)-ATPase activity. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9199200 |
| Grimminger F et al. | Synthesis of 4- and 5-series leukotrienes in the lung microvasculature challenged with Escherichia coli hemolysin: critical dependence on exogenous free fatty acid supply. | 1997 | Am. J. Respir. Cell Mol. Biol. | pmid:9070617 |
| Wheelan P and Murphy RC | Quantitation of 5-lipoxygenase products by electrospray mass spectrometry: effect of ethanol on zymosan-stimulated production of 5-lipoxygenase products by human neutrophils. | 1997 | Anal. Biochem. | pmid:9025916 |
| Zhang Y et al. | Synthesis of 5-oxo-6,8,11,14-eicosatetraenoic acid by human monocytes and lymphocytes. | 1996 | J. Leukoc. Biol. | pmid:8691070 |
| Cleland LG et al. | Dietary (n-9) eicosatrienoic acid from a cultured fungus inhibits leukotriene B4 synthesis in rats and the effect is modified by dietary linoleic acid. | 1996 | J. Nutr. | pmid:8648425 |
| Sozzani S et al. | Stimulating properties of 5-oxo-eicosanoids for human monocytes: synergism with monocyte chemotactic protein-1 and -3. | 1996 | J. Immunol. | pmid:8906847 |
| Edwin SS et al. | 5-Hydroxyeicosatetraenoic acid and human parturition. | 1996 | Prostaglandins | pmid:8873235 |
| Lin N et al. | Increased synthesis of specific eicosanoids in rejected corneal grafts. | 1996 | Curr. Eye Res. | pmid:9018436 |
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| Petrich K et al. | The suppression of 5-lipoxygenation of arachidonic acid in human polymorphonuclear leucocytes by the 15-lipoxygenase product (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid: structure-activity relationship and mechanism of action. | 1996 | Biochem. J. | pmid:8615788 |
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| Norgauer J et al. | Chemotactic 5-oxo-icosatetraenoic acids activate a unique pattern of neutrophil responses. Analysis of phospholipid metabolism, intracellular Ca2+ transients, actin reorganization, superoxide-anion production and receptor up-regulation. | 1996 | Eur. J. Biochem. | pmid:8665888 |
| Nakagawa Y and Ishii E | Changes in arachidonic acid metabolism and the aggregation of polymorphonuclear leukocytes in rats with streptozotocin-induced diabetes. | 1996 | Biochim. Biophys. Acta | pmid:8608172 |
| Shraga-Levine Z et al. | Arachidonic acid and lipoxygenase products stimulate protein kinase C beta mRNA levels in pituitary alpha T3-1 cell line: role in gonadotropin-releasing hormone action. | 1996 | Biochem. J. | pmid:8687415 |
| Hamer RR et al. | Dibenzoxepinone hydroxylamines and hydroxamic acids: dual inhibitors of cyclooxygenase and 5-lipoxygenase with potent topical antiinflammatory activity. | 1996 | J. Med. Chem. | pmid:8568814 |
| Sochanowicz B and Szumiel I | Arachidonic acid metabolism in murine lymphoma cell sublines differing in radiation sensitivity. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8951992 |
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| Kimura Y et al. | Effects of stilbenes isolated from medicinal plants on arachidonate metabolism and degranulation in human polymorphonuclear leukocytes. | 1995 | J Ethnopharmacol | pmid:7776662 |
| Powell WS et al. | 5-Oxo-6,8,11,14-eicosatetraenoic acid is a potent stimulator of human eosinophil migration. | 1995 | J. Immunol. | pmid:7706749 |
| Lehmann WD et al. | Quantitative lipoxygenase product profiling by gas chromatography negative-ion chemical ionization mass spectrometry. | 1995 | Anal. Biochem. | pmid:7710076 |
| Hamasaki Y et al. | Inhibition of leukotriene production by FK506 in rat basophilic leukemia-1 cells. | 1995 | Pharmacology | pmid:7538218 |
| Metzger K et al. | Lipoxygenase products in human saliva: patients with oral cancer compared to controls. | 1995 | Free Radic. Biol. Med. | pmid:7744301 |
| Kelefiotis D et al. | Eicosanoid-induced growth and signaling events in rat glomerular mesangial cells. | 1995 | Prostaglandins | pmid:7659782 |
| Romanelli F et al. | Arachidonic acid and its metabolites effects on testosterone production by rat Leydig cells. | 1995 | J. Endocrinol. Invest. | pmid:7615904 |
| Serhan CN | Leukocyte transmigration, chemotaxis, and oxygenated derivatives of arachidonic acid: when is chirality important? | 1995 | Am. J. Respir. Cell Mol. Biol. | pmid:7873189 |
| Wijkander J et al. | 5-Lipoxygenase products modulate the activity of the 85-kDa phospholipase A2 in human neutrophils. | 1995 | J. Biol. Chem. | pmid:7592874 |