5S-HETE

5s-hete is a lipid of Fatty Acyls (FA) class. 5s-hete often locates in Microsomes.

Cross Reference

Introduction

To understand associated biological information of 5S-HETE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 5S-HETE?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 5S-HETE

MeSH term MeSH ID Detail
Coronary Disease D003327 70 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Arteriosclerosis D001161 86 associated lipids
Leukemia D007938 74 associated lipids
Leukemia, Basophilic, Acute D015471 9 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Vomiting D014839 21 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Bronchial Spasm D001986 18 associated lipids
Obstetric Labor, Premature D007752 9 associated lipids
Per page 10 20 | Total 16

PubChem Associated disorders and diseases

What pathways are associated with 5S-HETE

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 5S-HETE?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 5S-HETE?

There are no associated biomedical information in the current reference collection.

What lipids are associated with 5S-HETE?

There are no associated biomedical information in the current reference collection.

What genes are associated with 5S-HETE?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with 5S-HETE?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 5S-HETE

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Per page 10 20 50 100 | Total 789
Authors Title Published Journal PubMed Link
Kuzuya T et al. Altered lipoxygenase metabolites and leukocyte involvement in an acute occlusion-reperfusion model of canine myocardial infarction. 1987 Jpn. Circ. J. pmid:3112436
Green FA et al. Lipoxygenase products from polymorphonuclear leukocytes and epithelial cells of human saliva. 1987 Arch. Biochem. Biophys. pmid:3116937
Westcott JY et al. Eicosanoids in human ventricular cerebrospinal fluid following severe brain injury. 1987 Prostaglandins pmid:2835791
Brown ML et al. Ionophore-induced metabolism of phospholipids and eicosanoid production in porcine aortic endothelial cells: selective release of arachidonic acid from diacyl and ether phospholipids. 1987 Biochim. Biophys. Acta pmid:3115300
O'Flaherty JT and Nishihira J 5-Hydroxyeicosatetraenoate promotes Ca2+ and protein kinase C mobilization in neutrophils. 1987 Biochem. Biophys. Res. Commun. pmid:3689361
Nigam S Inhibition of lipoxygenase products by retinoids in human blood cells. 1987 Dermatologica pmid:3691909
Vacas MI et al. Involvement of 5-lipoxygenase pathway in norepinephrine stimulation of rat pineal melatonin synthesis. 1987 Neuroendocrinology pmid:3431657
Kimura Y et al. Effects of an active substance isolated from the roots of Angelica shkiokiana on leukotriene and monohydroxyeicosatetreaenoic acid biosyntheses in human polymorphonuclear leukocytes. 1987 Planta Med. pmid:2832866
Littner MR et al. cAMP levels from endogenous and exogenous arachidonic acid in isolated dog lung. 1987 J. Appl. Physiol. pmid:3040660
Taylor SM et al. Arachidonic and eicosapentaenoic acid metabolism in bovine neutrophils and platelets: effect of calcium ionophore. 1987 J. Leukoc. Biol. pmid:3040877
Takayama H et al. Preferential incorporation of eicosanoid precursor fatty acids into human umbilical vein endothelial cell phospholipids. 1987 Biochim. Biophys. Acta pmid:2825796
Piomelli D et al. Metabolites of arachidonic acid in the nervous system of Aplysia: possible mediators of synaptic modulation. 1987 J. Neurosci. pmid:3119791
Walenga RW et al. Analysis of blood HETE levels by selected ion monitoring with ricinoleic acid as the internal standard. 1987 Prostaglandins pmid:3432563
Hatzelmann A and Ullrich V Regulation of 5-lipoxygenase activity by the glutathione status in human polymorphonuclear leukocytes. 1987 Eur. J. Biochem. pmid:2824200
Webb DS and Roth JA Relationship of glucocorticoid suppression of arachidonic acid metabolism to alteration of neutrophil function. 1987 J. Leukoc. Biol. pmid:3027218
McColl SR et al. Modulation of human neutrophil LTA hydrolase activity by phorbol myristate acetate. 1987 Biochem. Biophys. Res. Commun. pmid:2820409
Parker CW Lipid mediators produced through the lipoxygenase pathway. 1987 Annu. Rev. Immunol. pmid:3036183
Green FA et al. Monohydroxyeicosatetraenoic acid and leukotriene production by the inflammatory cells of Xenopus laevis. 1987 J. Exp. Zool. pmid:2821155
Walstra P et al. 12-Lipoxygenase from bovine polymorphonuclear leukocytes, an enzyme with leukotriene A4-synthase activity. 1987 Biochem. Biophys. Res. Commun. pmid:2825701
Skoog MT et al. Glutathione peroxidase is neither required nor kinetically competent for conversion of 5-HPETE to 5-HETE in rat PMN lysates. 1986 Prostaglandins pmid:3086940
Johnson HM et al. Second messenger role of arachidonic acid and its metabolites in interferon-gamma production. 1986 J. Immunol. pmid:2877026
Lewis JG and Adams DO Enhanced release of hydrogen peroxide and metabolites of arachidonic acid by macrophages from SENCAR mice following stimulation with phorbol esters. 1986 Cancer Res. pmid:3019532
O'Flaherty JT et al. Metabolism of 5-hydroxyicosatetraenoate by human neutrophils: production of a novel omega-oxidized derivative. 1986 J. Immunol. pmid:3095426
Shimanuki T et al. A kinetic analysis of peritoneal fluid cytology and arachidonic acid metabolism after abrasion and reabrasion of rabbit peritoneum. 1986 J. Surg. Res. pmid:3463833
Flynn DL et al. Inhibition of 5-hydroxy-eicosatetraenoic acid (5-HETE) formation in intact human neutrophils by naturally-occurring diarylheptanoids: inhibitory activities of curcuminoids and yakuchinones. 1986 Prostaglandins Leukot Med pmid:3460103
Westcott JY et al. Analysis of 6-keto PGF1 alpha, 5-HETE, and LTC4 in rat lung: comparison of GM/MS, RIA, and EIA. 1986 Prostaglandins pmid:3550900
Rhee BG et al. Platelet modulation of polymorphonuclear leukocyte shear induced aggregation. 1986 Blood pmid:3000480
Schafer AI et al. Incorporation of platelet and leukocyte lipoxygenase metabolites by cultured vascular cells. 1986 Blood pmid:3002525
Beetens JR et al. Ketoconazole inhibits the biosynthesis of leukotrienes in vitro and in vivo. 1986 Biochem. Pharmacol. pmid:3006695
Kanaji K et al. Deficient induction of leukotriene synthesis in human neutrophils by lipoxygenase-deficient platelets. 1986 Blood pmid:3006834
Ono N et al. Pharmacological studies on proglumetacin maleate, a new non-steroidal anti-inflammatory drug (4). Mode of action on anti-inflammatory activity. 1986 Jpn. J. Pharmacol. pmid:3102823
Atluru D et al. Arachidonic acid inhibits 5-lipoxygenase in human T cells. 1986 Biochem. Biophys. Res. Commun. pmid:3008733
Nielsen OH et al. Release of leukotriene B4 and 5-hydroxyeicosatetraenoic acid during phagocytosis of artificial immune complexes by peripheral neutrophils in chronic inflammatory bowel disease. 1986 Clin. Exp. Immunol. pmid:3024887
Hadjiagapiou C and Spector AA 12-Hydroxyeicosatetraenoic acid reduces prostacyclin production by endothelial cells. 1986 Prostaglandins pmid:3532204
Eskra JD et al. Solid-phase extraction and high-performance liquid chromatography analysis of lipoxygenase pathway products. 1986 Anal. Biochem. pmid:3010774
Kuhl P et al. Ebselen reduces the formation of LTB4 in human and porcine leukocytes by isomerisation to its 5S, 12R-6-trans-isomer. 1986 Prostaglandins pmid:3020614
Schröder JM Anthralin (1,8-dihydroxyanthrone) is a potent inhibitor of leukotriene production and LTB4-omega oxidation by human neutrophils. 1986 J. Invest. Dermatol. pmid:3021863
Scheffer J et al. Induction of inflammatory mediators from human polymorphonuclear granulocytes and rat mast cells by haemolysin-positive and -negative E. coli strains with different adhesins. 1986 Immunology pmid:2433215
Milvae RA et al. Involvement of lipoxygenase products of arachidonic acid metabolism in bovine luteal function. 1986 Biol. Reprod. pmid:3103701
Pickett WC and Douglas MB NaCN inhibits the stereospecific depletion of LTB4 by guinea pig polymorphonuclear leukocytes. 1986 Prostaglandins pmid:3012651
Skoog MT et al. 5-lipoxygenase from rat PMN lysate. 1986 Prostaglandins pmid:3012653
Erman A et al. Treatment with dexamethasone increases glomerular prostaglandin synthesis in rats. 1986 J. Pharmacol. Exp. Ther. pmid:3093672
McColl SR et al. Modulation by phorbol myristate acetate of arachidonic acid release and leukotriene synthesis by human polymorphonuclear leukocytes stimulated with A23187. 1986 Biochem. Biophys. Res. Commun. pmid:3026382
Laviolette M et al. Decreased leukotriene B4 synthesis in smokers' alveolar macrophages in vitro. 1986 J. Clin. Invest. pmid:3003154
Craven PA and DeRubertis FR Profiles of eicosanoid production by superficial and proliferative colonic epithelial cells and sub-epithelial colonic tissue. 1986 Prostaglandins pmid:3024236
Fondacaro JD Intestinal ion transport and diarrheal disease. 1986 Am. J. Physiol. pmid:2867681
Yamamoto S et al. Reactions of hydroperoxy-eicosatetraenoic acids with arachidonate 12- and 5-lipoxygenases purified from porcine leukocytes. 1986 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2949547
Richards CF et al. Specific incorporation of 5-hydroxy-6,8,11,14-eicosatetraenoic acid into phosphatidylcholine in human endothelial cells. 1986 Biochim. Biophys. Acta pmid:3004591
Ku EC et al. Effect of diclofenac sodium on the arachidonic acid cascade. 1986 Am. J. Med. pmid:3085488
König B et al. Role of Escherichia coli alpha-hemolysin and bacterial adherence in infection: requirement for release of inflammatory mediators from granulocytes and mast cells. 1986 Infect. Immun. pmid:2430890
Safayhi H et al. A novel biologically active seleno-organic compound--V. Inhibition by ebselen (PZ 51) of rat peritoneal neutrophil lipoxygenase. 1985 Biochem. Pharmacol. pmid:2990494
Lewis RA A presumptive role for leukotrienes in obstructive airways diseases. 1985 Chest pmid:2990824
Musch MW et al. Ionophore-stimulated lipoxygenase activity and histamine release in a cloned murine mast cell, MC9. 1985 Prostaglandins pmid:2408298
Kimura Y et al. Inhibition of the formation of 5-hydroxy-6,8,11,14-eicosatetraenoic acid from arachidonic acid in polymorphonuclear leukocytes by various coumarins. 1985 Biochim. Biophys. Acta pmid:3922420
Aisen PS et al. Circulating hydroxy fatty acids in familial Mediterranean fever. 1985 Proc. Natl. Acad. Sci. U.S.A. pmid:3919389
Kimura Y et al. Effects of stilbenes on arachidonate metabolism in leukocytes. 1985 Biochim. Biophys. Acta pmid:3922423
Johnson HG et al. 15-Hydroxyeicosatetraenoic acid is a potent inflammatory mediator and agonist of canine tracheal mucus secretion. 1985 Am. Rev. Respir. Dis. pmid:3923884
Farrar WL and Humes JL The role of arachidonic acid metabolism in the activities of interleukin 1 and 2. 1985 J. Immunol. pmid:3924998
Hirai A et al. Involvement of 5-lipoxygenase metabolites in ACTH-stimulated corticosteroidogenesis in rat adrenal glands. 1985 Prostaglandins pmid:3001830
Billah MM et al. Lipoxygenase products of arachidonic acid modulate biosynthesis of platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) by human neutrophils via phospholipase A2. 1985 J. Biol. Chem. pmid:3922982
Pakrasi PL et al. Cyclooxygenase and lipoxygenase pathways in the preimplantation rabbit uterus and blastocyst. 1985 Prostaglandins pmid:3923564
Ouwendijk RJ et al. Production of leukotrienes and prostaglandins by human ascites cells. 1985 Eur. J. Clin. Invest. pmid:3007158
Laychock SG Effects of hydroxyeicosatetraenoic acids on fatty acid esterification in phospholipids and insulin secretion in pancreatic islets. 1985 Endocrinology pmid:3926463
Dodge W and Thomas M The effect of 5-hydroxyeicosatetraenoic acid on the proliferation of granulocyte progenitors and embryonic fibroblasts of the chick. 1985 Biochem. Biophys. Res. Commun. pmid:4052072
Agins AP et al. Detection of a novel cyclooxygenase metabolite produced by human promyelocytic leukemia (HL-60) cells. 1985 Biochem. Biophys. Res. Commun. pmid:2982366
Capasso F et al. The role of calcium in eicosanoid production induced by ricinoleic acid or the calcium ionophore A23187. 1985 Prostaglandins pmid:2996053
Westcott JY and Murphy RC Effect of alcohols on arachidonic acid metabolism in murine mastocytoma cells and human polymorphonuclear leukocytes. 1985 Biochim. Biophys. Acta pmid:2982416
Williams JD et al. Intracellular retention of the 5-lipoxygenase pathway product, leukotriene B4, by human neutrophils activated with unopsonized zymosan. 1985 J. Immunol. pmid:2982947
Soberman RJ et al. Characterization and separation of the arachidonic acid 5-lipoxygenase and linoleic acid omega-6 lipoxygenase (arachidonic acid 15-lipoxygenase) of human polymorphonuclear leukocytes. 1985 J. Biol. Chem. pmid:3920219
Adesuyi SA et al. Lipoxygenase metabolism of arachidonic acid in brain. 1985 J. Neurochem. pmid:3928809
Mathur SN et al. Increased production of lipoxygenase products by cholesterol-rich mouse macrophages. 1985 Biochim. Biophys. Acta pmid:3931684
Chang J et al. Inhibition of platelet and neutrophil phospholipase A2 by hydroxyeicosatetraenoic acids (HETES). A novel pharmacological mechanism for regulating free fatty acid release. 1985 Biochem. Pharmacol. pmid:3994765
Shoam H and Razin E BW755C inhibits the 5-lipoxygenase in E-mast cells without affecting degranulation. 1985 Biochim. Biophys. Acta pmid:2413896
Fusco AC et al. Schistosoma mansoni: eicosanoid production by cercariae. 1985 Exp. Parasitol. pmid:3917929
O'Flaherty JT et al. Interactions of arachidonate metabolism and protein kinase C in mediating neutrophil function. 1985 Biochem. Biophys. Res. Commun. pmid:2985065
Pickett WC and Douglas MB Automated extraction and HPLC resolution of lipoxygenase and cyclooxygenase products utilizing high pressure column switching. 1985 Prostaglandins pmid:3919424
Turk J et al. Arachidonic acid metabolism in isolated pancreatic islets. III. Effects of exogenous lipoxygenase products and inhibitors on insulin secretion. 1985 Biochim. Biophys. Acta pmid:3919770
O'Flaherty JT Neutrophil degranulation: evidence pertaining to its mediation by the combined effects of leukotriene B4, platelet-activating factor, and 5-HETE. 1985 J. Cell. Physiol. pmid:2981891
Kimura Y et al. Effects of stilbene derivatives on arachidonate metabolism in leukocytes. 1985 Biochim. Biophys. Acta pmid:3931689
Chang J et al. Modulation by hydroxyeicosatetraenoic acids (HETEs) of arachidonic acid metabolism in mouse resident peritoneal macrophages. 1985 Eur. J. Pharmacol. pmid:3920057
Beckman JK et al. Stimulation by lipoxygenase products of superoxide anion production in FMLP-treated neutrophils. 1985 Lipids pmid:2989652
Tavares IA et al. Effects of isoxicam and other non-steroidal anti-inflammatory drugs on arachidonic acid metabolism by rat peritoneal leucocytes. 1985 J. Pharm. Pharmacol. pmid:2864427
Koike K et al. 5-Hydroxyeicosatetraenoic acid increases prolactin release from rat anterior pituitary cells. 1985 Endocrinology pmid:3921344
Vanderhoek JY et al. Endogenous hydroxyeicosatetraenoic acids stimulate the human polymorphonuclear leukocyte 15-lipoxygenase pathway. 1985 J. Biol. Chem. pmid:3934160
Peters SP et al. Arachidonic acid metabolism in purified human lung mast cells. 1984 J. Immunol. pmid:6199420
Vanderhoek JY and Bailey JM Activation of a 15-lipoxygenase/leukotriene pathway in human polymorphonuclear leukocytes by the anti-inflammatory agent ibuprofen. 1984 J. Biol. Chem. pmid:6427221
Goldman DW and Goetzl EJ Heterogeneity of human polymorphonuclear leukocyte receptors for leukotriene B4. Identification of a subset of high affinity receptors that transduce the chemotactic response. 1984 J. Exp. Med. pmid:6323613
Dahinden CA et al. Stereospecificity of leukotriene B4 and structure-function relationships for chemotaxis of human neutrophils. 1984 J. Immunol. pmid:6086758
Samhoun MN and Piper PJ The combined use of isolated strips of guinea-pig lung parenchyma and ileum as a sensitive and selective bioassay for leukotriene B4. 1984 Prostaglandins pmid:6087419
Nakamura T et al. Appearance of 5-hydroxy eicosatetraenoic acid in cerebrospinal fluid after subarachnoid haemorrhage. 1984 Med. Biol. pmid:6471929
Marom Z et al. The effects of corticosteroids on mucous glycoprotein secretion from human airways in vitro. 1984 Am. Rev. Respir. Dis. pmid:6703486
Metz SA et al. Effects on glucose-induced insulin secretion of lipoxygenase-derived metabolites of arachidonic acid. 1984 Diabetes pmid:6319213
McCarty M Can dietary selenium reduce leukotriene production? 1984 Med. Hypotheses pmid:6323934
Razin E et al. An analysis of the relationship between 5-lipoxygenase product generation and the secretion of preformed mediators from mouse bone marrow-derived mast cells. 1984 J. Immunol. pmid:6330206
[Pathogenicity factors and defense mechanisms in infectious diseases]. 1984 Verh Dtsch Ges Inn Med pmid:6151760
Serhan CN et al. Formation of leukotrienes and hydroxy acids by human neutrophils and platelets exposed to monosodium urate. 1984 Prostaglandins pmid:6328582
Ritchie DM et al. Evaluation of calcium entry blockers in several models of immediate hypersensitivity. 1984 J. Pharmacol. Exp. Ther. pmid:6202868
Marom Z et al. Prostaglandin-generating factor of anaphylaxis induces mucous glycoprotein release and the formation of lipoxygenase products of arachidonate from human airways. 1984 Prostaglandins pmid:6091187
Henke DC et al. Analysis of leukotrienes, prostaglandins, and other oxygenated metabolites of arachidonic acid by high-performance liquid chromatography. 1984 Anal. Biochem. pmid:6091494
Grabbe J et al. Identification of chemotactic lipoxygenase products of arachidonate metabolism in psoriatic skin. 1984 J. Invest. Dermatol. pmid:6096449