| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lung Neoplasms | D008175 | 171 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Weight Loss | D015431 | 56 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
| Uterine Neoplasms | D014594 | 18 associated lipids |
| Leiomyoma | D007889 | 8 associated lipids |
| Choroidal Neovascularization | D020256 | 5 associated lipids |
| Carcinoma, Adenoid Cystic | D003528 | 3 associated lipids |
isoliquiritigenin
Isoliquiritigenin is a lipid of Polyketides (PK) class. Isoliquiritigenin is associated with abnormalities such as abnormal fragmented structure, Gastric ulcer, Gastric mucosa lesion, Peptic Ulcer and Wiskott-Aldrich Syndrome. The involved functions are known as Mass-to-Charge Ratio, Anabolism, Oxidation, inhibitors and Energy Absorption. Isoliquiritigenin often locates in Microsomes, Liver, Hepatic, Microsomes, Immune system and Vacuole. The associated genes with Isoliquiritigenin are P4HTM gene, BCL2 gene, AP1AR gene, oxytocin, 1-desamino-(O-Et-Tyr)(2)- and ODAM gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of isoliquiritigenin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with isoliquiritigenin?
isoliquiritigenin is suspected in Gastric mucosa lesion, Gastric ulcer, Peptic Ulcer, Nodule, Infertility and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with isoliquiritigenin
PubChem Associated disorders and diseases
What pathways are associated with isoliquiritigenin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with isoliquiritigenin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with isoliquiritigenin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with isoliquiritigenin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with isoliquiritigenin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with isoliquiritigenin?
Knock-out
Knock-out are used in the study 'Two activators of in vitro fertilization in mice from licorice.' (Tung NH et al., 2015).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with isoliquiritigenin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yang N et al. | Glycyrrhiza uralensis flavonoids present in anti-asthma formula, ASHMIâ„¢, inhibit memory Th2 responses in vitro and in vivo. | 2013 | Phytother Res | pmid:23165939 |
| Li X et al. | A new flavonol from Oxytropis ochrocephala Bunge. | 2013 | Nat. Prod. Res. | pmid:22494026 |
| Foresti R et al. | Small molecule activators of the Nrf2-HO-1 antioxidant axis modulate heme metabolism and inflammation in BV2 microglia cells. | 2013 | Pharmacol. Res. | pmid:23942037 |
| Yuan X et al. | Involvement of endoplasmic reticulum stress in isoliquiritigenin-induced SKOV-3 cell apoptosis. | 2013 | Recent Pat Anticancer Drug Discov | pmid:22963151 |
| Lorusso V and Marech I | Novel plant-derived target drugs: a step forward from licorice? | 2013 | Expert Opin. Ther. Targets | pmid:23425066 |
| Simmler C et al. | Dynamic residual complexity of the isoliquiritigenin-liquiritigenin interconversion during bioassay. | 2013 | J. Agric. Food Chem. | pmid:23427769 |
| Lee SK et al. | The inhibitory effect of roasted licorice extract on human metastatic breast cancer cell-induced bone destruction. | 2013 | Phytother Res | pmid:23401151 |
| Hajirahimkhan A et al. | Evaluation of estrogenic activity of licorice species in comparison with hops used in botanicals for menopausal symptoms. | 2013 | PLoS ONE | pmid:23874474 |
| Chen H et al. | Isoliquiritigenin-induced effects on Nrf2 mediated antioxidant defence in the HL-60 cell monocytic differentiation. | 2013 | Cell Biol. Int. | pmid:23881796 |
| Zhao H et al. | Isoliquiritigen enhances the antitumour activity and decreases the genotoxic effect of cyclophosphamide. | 2013 | Molecules | pmid:23887720 |
| Chen YP et al. | Syntheses and evaluation of novel isoliquiritigenin derivatives as potential dual inhibitors for amyloid-beta aggregation and 5-lipoxygenase. | 2013 | Eur J Med Chem | pmid:23786711 |
| Zhang XY et al. | Preparation of isoliquiritigenin-loaded nanostructured lipid carrier and the in vivo evaluation in tumor-bearing mice. | 2013 | Eur J Pharm Sci | pmid:23624327 |
| Arai T et al. | Rikkunshito and isoliquiritigenin counteract 5-HT-induced 2C receptor-mediated activation of pro-opiomelanocortin neurons in the hypothalamic arcuate nucleus. | 2013 | Neuropeptides | pmid:23756052 |
| Yamada C et al. | Rikkunshito, a Japanese kampo medicine, ameliorates decreased feeding behavior via ghrelin and serotonin 2B receptor signaling in a novelty stress murine model. | 2013 | Biomed Res Int | pmid:24288687 |
| Robinson SJ et al. | Selected furanochalcones as inhibitors of monoamine oxidase. | 2013 | Bioorg. Med. Chem. Lett. | pmid:23860591 |
| Wang Z et al. | Dietary compound isoliquiritigenin inhibits breast cancer neoangiogenesis via VEGF/VEGFR-2 signaling pathway. | 2013 | PLoS ONE | pmid:23861918 |
| Li Y et al. | Isoliquiritigenin induces growth inhibition and apoptosis through downregulating arachidonic acid metabolic network and the deactivation of PI3K/Akt in human breast cancer. | 2013 | Toxicol. Appl. Pharmacol. | pmid:23747687 |
| Zhang X et al. | Natural antioxidant-isoliquiritigenin ameliorates contractile dysfunction of hypoxic cardiomyocytes via AMPK signaling pathway. | 2013 | Mediators Inflamm. | pmid:24163504 |
| Lee YK et al. | Pharmacokinetics of isoliquiritigenin and its metabolites in rats: low bioavailability is primarily due to the hepatic and intestinal metabolism. | 2013 | Planta Med. | pmid:24108436 |
| Hirchaud F et al. | Isoliquiritigenin induces caspase-dependent apoptosis via downregulation of HPV16 E6 expression in cervical cancer Ca Ski cells. | 2013 | Planta Med. | pmid:24214831 |