MeSH term | MeSH ID | Detail |
---|---|---|
Colonic Neoplasms | D003110 | 161 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
Lung Neoplasms | D008175 | 171 associated lipids |
Isoliquiritigenin is a lipid of Polyketides (PK) class. Isoliquiritigenin is associated with abnormalities such as abnormal fragmented structure, Gastric ulcer, Gastric mucosa lesion, Peptic Ulcer and Wiskott-Aldrich Syndrome. The involved functions are known as Mass-to-Charge Ratio, Anabolism, Oxidation, inhibitors and Energy Absorption. Isoliquiritigenin often locates in Microsomes, Liver, Hepatic, Microsomes, Immune system and Vacuole. The associated genes with Isoliquiritigenin are P4HTM gene, BCL2 gene, AP1AR gene, oxytocin, 1-desamino-(O-Et-Tyr)(2)- and ODAM gene. The related experimental models are Knock-out.
To understand associated biological information of isoliquiritigenin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
isoliquiritigenin is suspected in Gastric mucosa lesion, Gastric ulcer, Peptic Ulcer, Nodule, Infertility and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with isoliquiritigenin
MeSH term | MeSH ID | Detail |
---|---|---|
Colonic Neoplasms | D003110 | 161 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
Lung Neoplasms | D008175 | 171 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Two activators of in vitro fertilization in mice from licorice.' (Tung NH et al., 2015).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Chowdhury SA et al. | Tumor-specificity and apoptosis-inducing activity of stilbenes and flavonoids. | 2005 May-Jun | Anticancer Res. | pmid:16158945 |
Zorko BA et al. | Effects of ILTG on DAPK1 promoter methylation in colon and leukemia cancer cell lines. | 2010 | Anticancer Res. | pmid:21036707 |
Traboulsi H et al. | The Flavonoid Isoliquiritigenin Reduces Lung Inflammation and Mouse Morbidity during Influenza Virus Infection. | 2015 | Antimicrob. Agents Chemother. | pmid:26248373 |
Chen G et al. | Mammalian target of rapamycin regulates isoliquiritigenin-induced autophagic and apoptotic cell death in adenoid cystic carcinoma cells. | 2012 | Apoptosis | pmid:21956714 |
Yang HH et al. | Isoliquiritigenin Induces Cytotoxicity in PC-12 Cells In Vitro. | 2017 | Appl. Biochem. Biotechnol. | pmid:28488118 |
Kape R et al. | Isoliquiritigenin, a strong nod gene- and glyceollin resistance-inducing flavonoid from soybean root exudate. | 1992 | Appl. Environ. Microbiol. | pmid:1622242 |
Welle R and Grisebach H | Phytoalexin synthesis in soybean cells: elicitor induction of reductase involved in biosynthesis of 6'-deoxychalcone. | 1989 | Arch. Biochem. Biophys. | pmid:2500065 |
Yu H et al. | Effect of isoliquiritigenin for the treatment of atopic dermatitis-like skin lesions in mice. | 2017 | Arch. Dermatol. Res. | pmid:29026975 |
Herles C et al. | First bacterial chalcone isomerase isolated from Eubacterium ramulus. | 2004 | Arch. Microbiol. | pmid:15127184 |
Jin XY et al. | Isoliquiritigenin suppresses tumor necrosis factor-α-induced inflammation via peroxisome proliferator-activated receptor-γ in intestinal epithelial cells. | 2016 | Arch. Pharm. Res. | pmid:27539609 |