| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
isoliquiritigenin
Isoliquiritigenin is a lipid of Polyketides (PK) class. Isoliquiritigenin is associated with abnormalities such as abnormal fragmented structure, Gastric ulcer, Gastric mucosa lesion, Peptic Ulcer and Wiskott-Aldrich Syndrome. The involved functions are known as Mass-to-Charge Ratio, Anabolism, Oxidation, inhibitors and Energy Absorption. Isoliquiritigenin often locates in Microsomes, Liver, Hepatic, Microsomes, Immune system and Vacuole. The associated genes with Isoliquiritigenin are P4HTM gene, BCL2 gene, AP1AR gene, oxytocin, 1-desamino-(O-Et-Tyr)(2)- and ODAM gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of isoliquiritigenin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with isoliquiritigenin?
isoliquiritigenin is suspected in Gastric mucosa lesion, Gastric ulcer, Peptic Ulcer, Nodule, Infertility and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with isoliquiritigenin
PubChem Associated disorders and diseases
What pathways are associated with isoliquiritigenin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with isoliquiritigenin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with isoliquiritigenin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with isoliquiritigenin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with isoliquiritigenin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with isoliquiritigenin?
Knock-out
Knock-out are used in the study 'Two activators of in vitro fertilization in mice from licorice.' (Tung NH et al., 2015).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with isoliquiritigenin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yang YM et al. | Decrease of microRNA-122 causes hepatic insulin resistance by inducing protein tyrosine phosphatase 1B, which is reversed by licorice flavonoid. | 2012 | Hepatology | pmid:22807119 |
| Khamsan S et al. | The isolation of bioactive flavonoids from Jacaranda obtusifolia H. B. K. ssp. rhombifolia (G. F. W. Meijer) Gentry. | 2012 | Acta Pharm | pmid:22750816 |
| Fioravanti R et al. | Effects of polyphenol compounds on influenza A virus replication and definition of their mechanism of action. | 2012 | Bioorg. Med. Chem. | pmid:22743086 |
| Yuan X et al. | Isoliquiritigenin treatment induces apoptosis by increasing intracellular ROS levels in HeLa cells. | 2012 | J Asian Nat Prod Res | pmid:22694287 |
| Chen X et al. | Isoliquiritigenin inhibits the growth of multiple myeloma via blocking IL-6 signaling. | 2012 | J. Mol. Med. | pmid:22648519 |
| Lee HK et al. | Inhibitory effects of Glycyrrhizae radix and its active component, isoliquiritigenin, on Aβ(25-35)-induced neurotoxicity in cultured rat cortical neurons. | 2012 | Arch. Pharm. Res. | pmid:22644857 |
| Yang EJ et al. | Isoliquiritigenin isolated from Glycyrrhiza uralensis protects neuronal cells against glutamate-induced mitochondrial dysfunction. | 2012 | Biochem. Biophys. Res. Commun. | pmid:22538371 |
| Zhu L et al. | Licorice isoliquiritigenin suppresses RANKL-induced osteoclastogenesis in vitro and prevents inflammatory bone loss in vivo. | 2012 | Int. J. Biochem. Cell Biol. | pmid:22521613 |
| Li X et al. | A new flavonol from Oxytropis ochrocephala Bunge. | 2013 | Nat. Prod. Res. | pmid:22494026 |
| Hwang CK and Chun HS | Isoliquiritigenin isolated from licorice Glycyrrhiza uralensis prevents 6-hydroxydopamine-induced apoptosis in dopaminergic neurons. | 2012 | Biosci. Biotechnol. Biochem. | pmid:22451397 |
| Liu MM et al. | Discovery of flavonoid derivatives as anti-HCV agents via pharmacophore search combining molecular docking strategy. | 2012 | Eur J Med Chem | pmid:22445328 |
| Honda H et al. | Glycyrrhizin and isoliquiritigenin suppress the LPS sensor toll-like receptor 4/MD-2 complex signaling in a different manner. | 2012 | J. Leukoc. Biol. | pmid:22422925 |
| Shi Y et al. | Analgesic and uterine relaxant effects of isoliquiritigenin, a flavone from Glycyrrhiza glabra. | 2012 | Phytother Res | pmid:22389128 |
| Muanprasat C et al. | Novel action of the chalcone isoliquiritigenin as a cystic fibrosis transmembrane conductance regulator (CFTR) inhibitor: potential therapy for cholera and polycystic kidney disease. | 2012 | J. Pharmacol. Sci. | pmid:22186622 |
| Han B et al. | Determination of isoliquiritigenin and its distribution in mice by synchronous fluorescence spectrometry. | 2011 | Anal Sci | pmid:22076338 |
| Chen G et al. | Mammalian target of rapamycin regulates isoliquiritigenin-induced autophagic and apoptotic cell death in adenoid cystic carcinoma cells. | 2012 | Apoptosis | pmid:21956714 |
| Cho S et al. | Isoliquiritigenin, a chalcone compound, is a positive allosteric modulator of GABAA receptors and shows hypnotic effects. | 2011 | Biochem. Biophys. Res. Commun. | pmid:21945440 |
| Feldman M et al. | Comparative evaluation of two structurally related flavonoids, isoliquiritigenin and liquiritigenin, for their oral infection therapeutic potential. | 2011 | J. Nat. Prod. | pmid:21866899 |
| Cui FC et al. | Elucidation of the methyl transfer mechanism catalyzed by chalcone O-methyltransferase: a density functional study. | 2011 | J Comput Chem | pmid:21815175 |
| Yang H et al. | Isoliquiritigenin (4,2',4'-trihydroxychalcone): a new matrix-assisted laser desorption/ionization matrix with outstanding properties for the analysis of neutral oligosaccharides. | 2011 | Anal. Chim. Acta | pmid:21763807 |