MeSH term | MeSH ID | Detail |
---|---|---|
Leiomyoma | D007889 | 8 associated lipids |
Choroidal Neovascularization | D020256 | 5 associated lipids |
Carcinoma, Adenoid Cystic | D003528 | 3 associated lipids |
Isoliquiritigenin is a lipid of Polyketides (PK) class. Isoliquiritigenin is associated with abnormalities such as abnormal fragmented structure, Gastric ulcer, Gastric mucosa lesion, Peptic Ulcer and Wiskott-Aldrich Syndrome. The involved functions are known as Mass-to-Charge Ratio, Anabolism, Oxidation, inhibitors and Energy Absorption. Isoliquiritigenin often locates in Microsomes, Liver, Hepatic, Microsomes, Immune system and Vacuole. The associated genes with Isoliquiritigenin are P4HTM gene, BCL2 gene, AP1AR gene, oxytocin, 1-desamino-(O-Et-Tyr)(2)- and ODAM gene. The related experimental models are Knock-out.
To understand associated biological information of isoliquiritigenin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
isoliquiritigenin is suspected in Gastric mucosa lesion, Gastric ulcer, Peptic Ulcer, Nodule, Infertility and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with isoliquiritigenin
MeSH term | MeSH ID | Detail |
---|---|---|
Leiomyoma | D007889 | 8 associated lipids |
Choroidal Neovascularization | D020256 | 5 associated lipids |
Carcinoma, Adenoid Cystic | D003528 | 3 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Two activators of in vitro fertilization in mice from licorice.' (Tung NH et al., 2015).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Chen C et al. | Suppression of lung cancer progression by isoliquiritigenin through its metabolite 2, 4, 2', 4'-Tetrahydroxychalcone. | 2018 | J. Exp. Clin. Cancer Res. | pmid:30285892 |
Sechet E et al. | Natural molecules induce and synergize to boost expression of the human antimicrobial peptide β-defensin-3. | 2018 | Proc. Natl. Acad. Sci. U.S.A. | pmid:30275324 |
Zhang XR et al. | Isoliquiritigenin inhibits proliferation and metastasis of MKN28 gastric cancer cells by suppressing the PI3K/AKT/mTOR signaling pathway. | 2018 | Mol Med Rep | pmid:30066879 |
Zhang W et al. | Protective Effects of Isoliquiritigenin on LPS-Induced Acute Lung Injury by Activating PPAR-γ. | 2018 | Inflammation | pmid:29654430 |
Ji B et al. | Isoliquiritigenin blunts osteoarthritis by inhibition of bone resorption and angiogenesis in subchondral bone. | 2018 | Sci Rep | pmid:29379010 |
Genthe JR et al. | Ventromorphins: A New Class of Small Molecule Activators of the Canonical BMP Signaling Pathway. | 2017 | ACS Chem. Biol. | pmid:28787124 |
Gao F et al. | iRGD-modified lipid-polymer hybrid nanoparticles loaded with isoliquiritigenin to enhance anti-breast cancer effect and tumor-targeting ability. | 2017 | Int J Nanomedicine | pmid:28615942 |
Hou C et al. | Synthetic Isoliquiritigenin Inhibits Human Tongue Squamous Carcinoma Cells through Its Antioxidant Mechanism. | 2017 | Oxid Med Cell Longev | pmid:28203317 |
Yu H et al. | Effect of isoliquiritigenin for the treatment of atopic dermatitis-like skin lesions in mice. | 2017 | Arch. Dermatol. Res. | pmid:29026975 |
Chen HY et al. | Isoliquiritigenin Induces Autophagy and Inhibits Ovarian Cancer Cell Growth. | 2017 | Int J Mol Sci | pmid:28934130 |