| MeSH term | MeSH ID | Detail |
|---|---|---|
| Weight Loss | D015431 | 56 associated lipids |
| Choroidal Neovascularization | D020256 | 5 associated lipids |
| Carcinoma, Adenoid Cystic | D003528 | 3 associated lipids |
isoliquiritigenin
Isoliquiritigenin is a lipid of Polyketides (PK) class. Isoliquiritigenin is associated with abnormalities such as abnormal fragmented structure, Gastric ulcer, Gastric mucosa lesion, Peptic Ulcer and Wiskott-Aldrich Syndrome. The involved functions are known as Mass-to-Charge Ratio, Anabolism, Oxidation, inhibitors and Energy Absorption. Isoliquiritigenin often locates in Microsomes, Liver, Hepatic, Microsomes, Immune system and Vacuole. The associated genes with Isoliquiritigenin are P4HTM gene, BCL2 gene, AP1AR gene, oxytocin, 1-desamino-(O-Et-Tyr)(2)- and ODAM gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of isoliquiritigenin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with isoliquiritigenin?
isoliquiritigenin is suspected in Gastric mucosa lesion, Gastric ulcer, Peptic Ulcer, Nodule, Infertility and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with isoliquiritigenin
PubChem Associated disorders and diseases
What pathways are associated with isoliquiritigenin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with isoliquiritigenin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with isoliquiritigenin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with isoliquiritigenin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with isoliquiritigenin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with isoliquiritigenin?
Knock-out
Knock-out are used in the study 'Two activators of in vitro fertilization in mice from licorice.' (Tung NH et al., 2015).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with isoliquiritigenin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yan F et al. | Isoliquiritigenin suppresses human T Lymphocyte activation via covalently binding cysteine 46 of IκB kinase. | 2017 | Oncotarget | pmid:27626700 |
| Genthe JR et al. | Ventromorphins: A New Class of Small Molecule Activators of the Canonical BMP Signaling Pathway. | 2017 | ACS Chem. Biol. | pmid:28787124 |
| Gao F et al. | iRGD-modified lipid-polymer hybrid nanoparticles loaded with isoliquiritigenin to enhance anti-breast cancer effect and tumor-targeting ability. | 2017 | Int J Nanomedicine | pmid:28615942 |
| Hou C et al. | Synthetic Isoliquiritigenin Inhibits Human Tongue Squamous Carcinoma Cells through Its Antioxidant Mechanism. | 2017 | Oxid Med Cell Longev | pmid:28203317 |
| Yu H et al. | Effect of isoliquiritigenin for the treatment of atopic dermatitis-like skin lesions in mice. | 2017 | Arch. Dermatol. Res. | pmid:29026975 |
| Chen HY et al. | Isoliquiritigenin Induces Autophagy and Inhibits Ovarian Cancer Cell Growth. | 2017 | Int J Mol Sci | pmid:28934130 |
| Bueno-Silva B et al. | The effect of seasons on Brazilian red propolis and its botanical source: chemical composition and antibacterial activity. | 2017 | Nat. Prod. Res. | pmid:27701899 |
| Zeng J et al. | Isoliquiritigenin alleviates early brain injury after experimental intracerebral hemorrhage via suppressing ROS- and/or NF-κB-mediated NLRP3 inflammasome activation by promoting Nrf2 antioxidant pathway. | 2017 | J Neuroinflammation | pmid:28610608 |
| Köksal Z et al. | The inhibition effects of some natural products on lactoperoxidase purified from bovine milk. | 2017 | J. Biochem. Mol. Toxicol. | pmid:28594102 |
| Kim DH et al. | Isoliquiritigenin inhibits the proliferation of human renal carcinoma Caki cells through the ROS-mediated regulation of the Jak2/STAT3 pathway. | 2017 | Oncol. Rep. | pmid:28560439 |
| Yang HH et al. | Isoliquiritigenin Induces Cytotoxicity in PC-12 Cells In Vitro. | 2017 | Appl. Biochem. Biotechnol. | pmid:28488118 |
| Chen XY et al. | Reprogramming induced by isoliquiritigenin diminishes melanoma cachexia through mTORC2-AKT-GSK3β signaling. | 2017 | Oncotarget | pmid:28410220 |
| Boyapelly K et al. | Synthesis and Characterization of a Phosphate Prodrug of Isoliquiritigenin. | 2017 | J. Nat. Prod. | pmid:28252963 |
| Chi JH et al. | Isoliquiritigenin inhibits TNF-α-induced release of high-mobility group box 1 through activation of HDAC in human intestinal epithelial HT-29 cells. | 2017 | Eur. J. Pharmacol. | pmid:28012970 |
| Wu M et al. | Isoliquiritigenin decreases the incidence of colitis-associated colorectal cancer by modulating the intestinal microbiota. | 2016 | Oncotarget | pmid:27863401 |
| Wu CH et al. | Isoliquiritigenin induces apoptosis and autophagy and inhibits endometrial cancer growth in mice. | 2016 | Oncotarget | pmid:27708238 |
| Jin XY et al. | Isoliquiritigenin suppresses tumor necrosis factor-α-induced inflammation via peroxisome proliferator-activated receptor-γ in intestinal epithelial cells. | 2016 | Arch. Pharm. Res. | pmid:27539609 |
| Hsia SM et al. | Isoliquiritigenin as a cause of DNA damage and inhibitor of ataxia-telangiectasia mutated expression leading to G2/M phase arrest and apoptosis in oral squamous cell carcinoma. | 2016 | Head Neck | pmid:25580586 |
| Yang EJ et al. | The comparison of neuroprotective effects of isoliquiritigenin and its Phase I metabolites against glutamate-induced HT22 cell death. | 2016 | Bioorg. Med. Chem. Lett. | pmid:27815122 |
| Chen X et al. | Differentiation-inducing and anti-proliferative activities of isoliquiritigenin and all-trans-retinoic acid on B16F0 melanoma cells: Mechanisms profiling by RNA-seq. | 2016 | Gene | pmid:27461947 |