| MeSH term | MeSH ID | Detail |
|---|---|---|
| Carcinoma, Adenoid Cystic | D003528 | 3 associated lipids |
| Choroidal Neovascularization | D020256 | 5 associated lipids |
| Leiomyoma | D007889 | 8 associated lipids |
| Uterine Neoplasms | D014594 | 18 associated lipids |
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Weight Loss | D015431 | 56 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
isoliquiritigenin
Isoliquiritigenin is a lipid of Polyketides (PK) class. Isoliquiritigenin is associated with abnormalities such as abnormal fragmented structure, Gastric ulcer, Gastric mucosa lesion, Peptic Ulcer and Wiskott-Aldrich Syndrome. The involved functions are known as Mass-to-Charge Ratio, Anabolism, Oxidation, inhibitors and Energy Absorption. Isoliquiritigenin often locates in Microsomes, Liver, Hepatic, Microsomes, Immune system and Vacuole. The associated genes with Isoliquiritigenin are P4HTM gene, BCL2 gene, AP1AR gene, oxytocin, 1-desamino-(O-Et-Tyr)(2)- and ODAM gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of isoliquiritigenin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with isoliquiritigenin?
isoliquiritigenin is suspected in Gastric mucosa lesion, Gastric ulcer, Peptic Ulcer, Nodule, Infertility and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with isoliquiritigenin
PubChem Associated disorders and diseases
What pathways are associated with isoliquiritigenin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with isoliquiritigenin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with isoliquiritigenin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with isoliquiritigenin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with isoliquiritigenin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with isoliquiritigenin?
Knock-out
Knock-out are used in the study 'Two activators of in vitro fertilization in mice from licorice.' (Tung NH et al., 2015).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with isoliquiritigenin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chowdhury SA et al. | Tumor-specificity and apoptosis-inducing activity of stilbenes and flavonoids. | 2005 May-Jun | Anticancer Res. | pmid:16158945 |
| Hsu YL et al. | Isoliquiritigenin inhibits cell proliferation and induces apoptosis in human hepatoma cells. | 2005 | Planta Med. | pmid:15729620 |
| Hsu YL et al. | Isoliquiritigenin induces apoptosis and cell cycle arrest through p53-dependent pathway in Hep G2 cells. | 2005 | Life Sci. | pmid:15878356 |
| De Bartolo L et al. | Effect of isoliquiritigenin on viability and differentiated functions of human hepatocytes maintained on PEEK-WC-polyurethane membranes. | 2005 | Biomaterials | pmid:15927248 |
| Bomati EK et al. | Structural elucidation of chalcone reductase and implications for deoxychalcone biosynthesis. | 2005 | J. Biol. Chem. | pmid:15970585 |
| Ma CJ et al. | One step isolation and purification of liquiritigenin and isoliquiritigenin from Glycyrrhiza uralensis Risch. using high-speed counter-current chromatography. | 2005 | J Chromatogr A | pmid:16007997 |
| Eggler AL et al. | Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2. | 2005 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16006525 |
| Cao Y et al. | Determination of liquiritigenin and isoliquiritigenin in Glycyrrhiza uralensis and its medicinal preparations by capillary electrophoresis with electrochemical detection. | 2004 | J Chromatogr A | pmid:15296407 |
| Hsu YL et al. | Isoliquiritigenin inhibits the proliferation and induces the apoptosis of human non-small cell lung cancer a549 cells. | 2004 | Clin. Exp. Pharmacol. Physiol. | pmid:15236626 |
| Herles C et al. | First bacterial chalcone isomerase isolated from Eubacterium ramulus. | 2004 | Arch. Microbiol. | pmid:15127184 |
| Takahashi T et al. | Isoliquiritigenin, a flavonoid from licorice, reduces prostaglandin E2 and nitric oxide, causes apoptosis, and suppresses aberrant crypt foci development. | 2004 | Cancer Sci. | pmid:15132774 |
| Basu NK et al. | Differential and special properties of the major human UGT1-encoded gastrointestinal UDP-glucuronosyltransferases enhance potential to control chemical uptake. | 2004 | J. Biol. Chem. | pmid:14557274 |
| Oguro S et al. | Probing biosynthesis of plant polyketides with synthetic N-acetylcysteamine thioesters. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15530429 |
| Ii T et al. | Induction of cell cycle arrest and p21(CIP1/WAF1) expression in human lung cancer cells by isoliquiritigenin. | 2004 | Cancer Lett. | pmid:15050731 |
| Sung MW and Li PC | Chemical analysis of raw, dry-roasted, and honey-roasted licorice by capillary electrophoresis. | 2004 | Electrophoresis | pmid:15490450 |
| Kanazawa M et al. | Isoliquiritigenin inhibits the growth of prostate cancer. | 2003 | Eur. Urol. | pmid:12706007 |
| Dixon RA and Sumner LW | Legume natural products: understanding and manipulating complex pathways for human and animal health. | 2003 | Plant Physiol. | pmid:12644640 |
| Wang YF et al. | [Studies on chemical constituents from the root of Polygonatum kingianum]. | 2003 | Zhongguo Zhong Yao Za Zhi | pmid:15015331 |
| Nerya O et al. | Glabrene and isoliquiritigenin as tyrosinase inhibitors from licorice roots. | 2003 | J. Agric. Food Chem. | pmid:12590456 |
| Martin HJ et al. | The inhibitory effects of flavonoids and antiestrogens on the Glut1 glucose transporter in human erythrocytes. | 2003 | Chem. Biol. Interact. | pmid:14642735 |