| MeSH term | MeSH ID | Detail |
|---|---|---|
| Carcinoma, Adenoid Cystic | D003528 | 3 associated lipids |
| Choroidal Neovascularization | D020256 | 5 associated lipids |
| Leiomyoma | D007889 | 8 associated lipids |
| Uterine Neoplasms | D014594 | 18 associated lipids |
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Weight Loss | D015431 | 56 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
isoliquiritigenin
Isoliquiritigenin is a lipid of Polyketides (PK) class. Isoliquiritigenin is associated with abnormalities such as abnormal fragmented structure, Gastric ulcer, Gastric mucosa lesion, Peptic Ulcer and Wiskott-Aldrich Syndrome. The involved functions are known as Mass-to-Charge Ratio, Anabolism, Oxidation, inhibitors and Energy Absorption. Isoliquiritigenin often locates in Microsomes, Liver, Hepatic, Microsomes, Immune system and Vacuole. The associated genes with Isoliquiritigenin are P4HTM gene, BCL2 gene, AP1AR gene, oxytocin, 1-desamino-(O-Et-Tyr)(2)- and ODAM gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of isoliquiritigenin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with isoliquiritigenin?
isoliquiritigenin is suspected in Gastric mucosa lesion, Gastric ulcer, Peptic Ulcer, Nodule, Infertility and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with isoliquiritigenin
PubChem Associated disorders and diseases
What pathways are associated with isoliquiritigenin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with isoliquiritigenin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with isoliquiritigenin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with isoliquiritigenin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with isoliquiritigenin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with isoliquiritigenin?
Knock-out
Knock-out are used in the study 'Two activators of in vitro fertilization in mice from licorice.' (Tung NH et al., 2015).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with isoliquiritigenin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yang N et al. | Glycyrrhiza uralensis flavonoids present in anti-asthma formula, ASHMIâ„¢, inhibit memory Th2 responses in vitro and in vivo. | 2013 | Phytother Res | pmid:23165939 |
| Zhang X et al. | Natural antioxidant-isoliquiritigenin ameliorates contractile dysfunction of hypoxic cardiomyocytes via AMPK signaling pathway. | 2013 | Mediators Inflamm. | pmid:24163504 |
| Lee YK et al. | Pharmacokinetics of isoliquiritigenin and its metabolites in rats: low bioavailability is primarily due to the hepatic and intestinal metabolism. | 2013 | Planta Med. | pmid:24108436 |
| Hirchaud F et al. | Isoliquiritigenin induces caspase-dependent apoptosis via downregulation of HPV16 E6 expression in cervical cancer Ca Ski cells. | 2013 | Planta Med. | pmid:24214831 |
| Hong H et al. | Rat α-Fetoprotein binding affinities of a large set of structurally diverse chemicals elucidated the relationships between structures and binding affinities. | 2012 | Chem. Res. Toxicol. | pmid:23013281 |
| Liu MM et al. | Discovery of flavonoid derivatives as anti-HCV agents via pharmacophore search combining molecular docking strategy. | 2012 | Eur J Med Chem | pmid:22445328 |
| Zhu L et al. | Licorice isoliquiritigenin suppresses RANKL-induced osteoclastogenesis in vitro and prevents inflammatory bone loss in vivo. | 2012 | Int. J. Biochem. Cell Biol. | pmid:22521613 |
| Chen G et al. | Mammalian target of rapamycin regulates isoliquiritigenin-induced autophagic and apoptotic cell death in adenoid cystic carcinoma cells. | 2012 | Apoptosis | pmid:21956714 |
| Lee JE et al. | Molecular signatures in response to Isoliquiritigenin in lymphoblastoid cell lines. | 2012 | Biochem. Biophys. Res. Commun. | pmid:22995316 |
| Muanprasat C et al. | Novel action of the chalcone isoliquiritigenin as a cystic fibrosis transmembrane conductance regulator (CFTR) inhibitor: potential therapy for cholera and polycystic kidney disease. | 2012 | J. Pharmacol. Sci. | pmid:22186622 |
| Fioravanti R et al. | Effects of polyphenol compounds on influenza A virus replication and definition of their mechanism of action. | 2012 | Bioorg. Med. Chem. | pmid:22743086 |
| Yang YM et al. | Decrease of microRNA-122 causes hepatic insulin resistance by inducing protein tyrosine phosphatase 1B, which is reversed by licorice flavonoid. | 2012 | Hepatology | pmid:22807119 |
| Khamsan S et al. | The isolation of bioactive flavonoids from Jacaranda obtusifolia H. B. K. ssp. rhombifolia (G. F. W. Meijer) Gentry. | 2012 | Acta Pharm | pmid:22750816 |
| Honda H et al. | Glycyrrhizin and isoliquiritigenin suppress the LPS sensor toll-like receptor 4/MD-2 complex signaling in a different manner. | 2012 | J. Leukoc. Biol. | pmid:22422925 |
| Hwang CK and Chun HS | Isoliquiritigenin isolated from licorice Glycyrrhiza uralensis prevents 6-hydroxydopamine-induced apoptosis in dopaminergic neurons. | 2012 | Biosci. Biotechnol. Biochem. | pmid:22451397 |
| Yuan X et al. | Isoliquiritigenin treatment induces apoptosis by increasing intracellular ROS levels in HeLa cells. | 2012 | J Asian Nat Prod Res | pmid:22694287 |
| Lee HK et al. | Inhibitory effects of Glycyrrhizae radix and its active component, isoliquiritigenin, on Aβ(25-35)-induced neurotoxicity in cultured rat cortical neurons. | 2012 | Arch. Pharm. Res. | pmid:22644857 |
| Chen X et al. | Isoliquiritigenin inhibits the growth of multiple myeloma via blocking IL-6 signaling. | 2012 | J. Mol. Med. | pmid:22648519 |
| Chen X et al. | Isoliquiritigenin-induced differentiation in mouse melanoma B16F0 cell line. | 2012 | Oxid Med Cell Longev | pmid:23304254 |
| Chen H et al. | NADPH oxidase-derived reactive oxygen species are involved in the HL-60 cell monocytic differentiation induced by isoliquiritigenin. | 2012 | Molecules | pmid:23147401 |