isoliquiritigenin

Isoliquiritigenin is a lipid of Polyketides (PK) class. Isoliquiritigenin is associated with abnormalities such as abnormal fragmented structure, Gastric ulcer, Gastric mucosa lesion, Peptic Ulcer and Wiskott-Aldrich Syndrome. The involved functions are known as Mass-to-Charge Ratio, Anabolism, Oxidation, inhibitors and Energy Absorption. Isoliquiritigenin often locates in Microsomes, Liver, Hepatic, Microsomes, Immune system and Vacuole. The associated genes with Isoliquiritigenin are P4HTM gene, BCL2 gene, AP1AR gene, oxytocin, 1-desamino-(O-Et-Tyr)(2)- and ODAM gene. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of isoliquiritigenin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with isoliquiritigenin?

isoliquiritigenin is suspected in Gastric mucosa lesion, Gastric ulcer, Peptic Ulcer, Nodule, Infertility and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with isoliquiritigenin

MeSH term MeSH ID Detail
Choroidal Neovascularization D020256 5 associated lipids
Weight Loss D015431 56 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Precancerous Conditions D011230 48 associated lipids
Lung Neoplasms D008175 171 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Leiomyoma D007889 8 associated lipids
Glioma D005910 112 associated lipids
Carcinoma, Adenoid Cystic D003528 3 associated lipids
Per page 10 20 | Total 13

PubChem Associated disorders and diseases

What pathways are associated with isoliquiritigenin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with isoliquiritigenin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with isoliquiritigenin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with isoliquiritigenin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with isoliquiritigenin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with isoliquiritigenin?

Knock-out

Knock-out are used in the study 'Two activators of in vitro fertilization in mice from licorice.' (Tung NH et al., 2015).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with isoliquiritigenin

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Authors Title Published Journal PubMed Link
Wu M et al. Isoliquiritigenin decreases the incidence of colitis-associated colorectal cancer by modulating the intestinal microbiota. 2016 Oncotarget pmid:27863401
Wu CH et al. Isoliquiritigenin induces apoptosis and autophagy and inhibits endometrial cancer growth in mice. 2016 Oncotarget pmid:27708238
Jin XY et al. Isoliquiritigenin suppresses tumor necrosis factor-α-induced inflammation via peroxisome proliferator-activated receptor-γ in intestinal epithelial cells. 2016 Arch. Pharm. Res. pmid:27539609
Cao L- et al. Isoliquiritigenin protects against triptolide-induced hepatotoxicity in mice through Nrf2 activation. 2016 Pharmazie pmid:29441915
Weis KE and Raetzman LT Isoliquiritigenin exhibits anti-proliferative properties in the pituitary independent of estrogen receptor function. 2016 Toxicol. Appl. Pharmacol. pmid:27702603
Molitor C et al. Aurone synthase is a catechol oxidase with hydroxylase activity and provides insights into the mechanism of plant polyphenol oxidases. 2016 Proc. Natl. Acad. Sci. U.S.A. pmid:26976571
Gaur R et al. Drug Resistance Reversal Potential of Isoliquiritigenin and Liquiritigenin Isolated from Glycyrrhiza glabra Against Methicillin-Resistant Staphylococcus aureus (MRSA). 2016 Phytother Res pmid:27388327
Yang EJ et al. The comparison of neuroprotective effects of isoliquiritigenin and its Phase I metabolites against glutamate-induced HT22 cell death. 2016 Bioorg. Med. Chem. Lett. pmid:27815122
Chen X et al. Differentiation-inducing and anti-proliferative activities of isoliquiritigenin and all-trans-retinoic acid on B16F0 melanoma cells: Mechanisms profiling by RNA-seq. 2016 Gene pmid:27461947
Mahalingam S et al. Effects of isoliquiritigenin on ovarian antral follicle growth and steroidogenesis. 2016 Reprod. Toxicol. pmid:27773742