isoliquiritigenin

Isoliquiritigenin is a lipid of Polyketides (PK) class. Isoliquiritigenin is associated with abnormalities such as abnormal fragmented structure, Gastric ulcer, Gastric mucosa lesion, Peptic Ulcer and Wiskott-Aldrich Syndrome. The involved functions are known as Mass-to-Charge Ratio, Anabolism, Oxidation, inhibitors and Energy Absorption. Isoliquiritigenin often locates in Microsomes, Liver, Hepatic, Microsomes, Immune system and Vacuole. The associated genes with Isoliquiritigenin are P4HTM gene, BCL2 gene, AP1AR gene, oxytocin, 1-desamino-(O-Et-Tyr)(2)- and ODAM gene. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of isoliquiritigenin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with isoliquiritigenin?

isoliquiritigenin is suspected in Gastric mucosa lesion, Gastric ulcer, Peptic Ulcer, Nodule, Infertility and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with isoliquiritigenin

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Precancerous Conditions D011230 48 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Glioma D005910 112 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Leiomyoma D007889 8 associated lipids
Per page 10 20 | Total 13

PubChem Associated disorders and diseases

What pathways are associated with isoliquiritigenin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with isoliquiritigenin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with isoliquiritigenin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with isoliquiritigenin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with isoliquiritigenin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with isoliquiritigenin?

Knock-out

Knock-out are used in the study 'Two activators of in vitro fertilization in mice from licorice.' (Tung NH et al., 2015).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with isoliquiritigenin

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Authors Title Published Journal PubMed Link
pmid:
Krishnaveni KS and Rao JV An isoflavone from Pterocarpus santalinus. 2000 Phytochemistry pmid:10724187
Kong LD et al. Inhibition of xanthine oxidase by liquiritigenin and isoliquiritigenin isolated from Sinofranchetia chinensis. 2000 Cell. Mol. Life Sci. pmid:10823249
Baba M et al. Saponins isolated from Allium chinense G. Don and antitumor-promoting activities of isoliquiritigenin and laxogenin from the same drug. 2000 Biol. Pharm. Bull. pmid:10823685
Iwashita K et al. Flavonoids inhibit cell growth and induce apoptosis in B16 melanoma 4A5 cells. 2000 Biosci. Biotechnol. Biochem. pmid:11055382
Shibata S A drug over the millennia: pharmacognosy, chemistry, and pharmacology of licorice. 2000 Yakugaku Zasshi pmid:11082698
Zubieta C et al. Structures of two natural product methyltransferases reveal the basis for substrate specificity in plant O-methyltransferases. 2001 Nat. Struct. Biol. pmid:11224575
Tanaka S et al. Influence of natural and synthetic compounds on cell surface expression of cell adhesion molecules, ICAM-1 and VCAM-1. 2001 Planta Med. pmid:11301853
Pan X et al. In vitro inhibition of rat monoamine oxidase by liquiritigenin and isoliquiritigenin isolated from Sinofranchetia chinensis. 2000 Acta Pharmacol. Sin. pmid:11501051
Ma J et al. Apoptosis induced by isoliquiritigenin in human gastric cancer MGC-803 cells. 2001 Planta Med. pmid:11731922