Negi S et al. |
Stable cellular models of nuclear receptor PXR for high-throughput evaluation of small molecules. |
2018 |
Toxicol In Vitro |
pmid:29933105
|
Chen J et al. |
Isoliquiritigenin Suppresses Osteosarcoma U2OS Cell Proliferation and Invasion by Regulating the PI3K/Akt Signalling Pathway. |
2018 |
Chemotherapy |
pmid:29936511
|
Liu X et al. |
Isoliquiritigenin Ameliorates Acute Pancreatitis in Mice via Inhibition of Oxidative Stress and Modulation of the Nrf2/HO-1 Pathway. |
2018 |
Oxid Med Cell Longev |
pmid:29854090
|
Nakamura S et al. |
Isoliquiritigenin Ameliorates Indomethacin-Induced Small Intestinal Damage by Inhibiting NOD-Like Receptor Family, Pyrin Domain-Containing 3 Inflammasome Activation. |
2018 |
Pharmacology |
pmid:29393276
|
Zhang B et al. |
Antineoplastic activity of isoliquiritigenin, a chalcone compound, in androgen-independent human prostate cancer cells linked to G2/M cell cycle arrest and cell apoptosis. |
2018 |
Eur. J. Pharmacol. |
pmid:29277717
|
Lin Y et al. |
Isoliquiritigenin inhibits the proliferation and induces the differentiation of human glioma stem cells. |
2018 |
Oncol. Rep. |
pmid:29251326
|
Yang Z et al. |
Autophagy participates in isoliquiritigenin-induced melanin degradation in human epidermal keratinocytes through PI3K/AKT/mTOR signaling. |
2018 |
Biomed. Pharmacother. |
pmid:29091873
|
Li Y et al. |
Drug interaction study of flavonoids toward CYP3A4 and their quantitative structure activity relationship (QSAR) analysis for predicting potential effects. |
2018 |
Toxicol. Lett. |
pmid:29753067
|
Lian D et al. |
Cathepsin B-Mediated NLRP3 Inflammasome Formation and Activation in Angiotensin II -Induced Hypertensive Mice: Role of Macrophage Digestion Dysfunction. |
2018 |
Cell. Physiol. Biochem. |
pmid:30359991
|
Chen C et al. |
Suppression of lung cancer progression by isoliquiritigenin through its metabolite 2, 4, 2', 4'-Tetrahydroxychalcone. |
2018 |
J. Exp. Clin. Cancer Res. |
pmid:30285892
|
Sechet E et al. |
Natural molecules induce and synergize to boost expression of the human antimicrobial peptide β-defensin-3. |
2018 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:30275324
|
Zhang XR et al. |
Isoliquiritigenin inhibits proliferation and metastasis of MKN28 gastric cancer cells by suppressing the PI3K/AKT/mTOR signaling pathway. |
2018 |
Mol Med Rep |
pmid:30066879
|
Zhang W et al. |
Protective Effects of Isoliquiritigenin on LPS-Induced Acute Lung Injury by Activating PPAR-γ. |
2018 |
Inflammation |
pmid:29654430
|
Ji B et al. |
Isoliquiritigenin blunts osteoarthritis by inhibition of bone resorption and angiogenesis in subchondral bone. |
2018 |
Sci Rep |
pmid:29379010
|
Chen X et al. |
Isoliquiritigenin protects against sepsis-induced lung and liver injury by reducing inflammatory responses. |
2018 |
Biochem. Biophys. Res. Commun. |
pmid:29180018
|
Yan F et al. |
Isoliquiritigenin suppresses human T Lymphocyte activation via covalently binding cysteine 46 of IκB kinase. |
2017 |
Oncotarget |
pmid:27626700
|
Genthe JR et al. |
Ventromorphins: A New Class of Small Molecule Activators of the Canonical BMP Signaling Pathway. |
2017 |
ACS Chem. Biol. |
pmid:28787124
|
Gao F et al. |
iRGD-modified lipid-polymer hybrid nanoparticles loaded with isoliquiritigenin to enhance anti-breast cancer effect and tumor-targeting ability. |
2017 |
Int J Nanomedicine |
pmid:28615942
|
Hou C et al. |
Synthetic Isoliquiritigenin Inhibits Human Tongue Squamous Carcinoma Cells through Its Antioxidant Mechanism. |
2017 |
Oxid Med Cell Longev |
pmid:28203317
|
Yu H et al. |
Effect of isoliquiritigenin for the treatment of atopic dermatitis-like skin lesions in mice. |
2017 |
Arch. Dermatol. Res. |
pmid:29026975
|
Chen HY et al. |
Isoliquiritigenin Induces Autophagy and Inhibits Ovarian Cancer Cell Growth. |
2017 |
Int J Mol Sci |
pmid:28934130
|
Chen T et al. |
The inhibitory effect of Isoliquiritigenin on the proliferation of human arterial smooth muscle cell. |
2017 |
BMC Pharmacol Toxicol |
pmid:28716056
|
Yerra VG et al. |
Isoliquiritigenin reduces oxidative damage and alleviates mitochondrial impairment by SIRT1 activation in experimental diabetic neuropathy. |
2017 |
J. Nutr. Biochem. |
pmid:28528294
|
Bueno-Silva B et al. |
The effect of seasons on Brazilian red propolis and its botanical source: chemical composition and antibacterial activity. |
2017 |
Nat. Prod. Res. |
pmid:27701899
|
Wu N et al. |
Construction of a chalcone reductase expression vector and transformation of soybean plants. |
2017 |
Mol Med Rep |
pmid:28901382
|
Kuang Y et al. |
Screening of hepatoprotective compounds from licorice against carbon tetrachloride and acetaminophen induced HepG2 cells injury. |
2017 |
Phytomedicine |
pmid:28899510
|
Patricia Moreno-Londoño A et al. |
Isoliquiritigenin pretreatment attenuates cisplatin induced proximal tubular cells (LLC-PK1) death and enhances the toxicity induced by this drug in bladder cancer T24Â cell line. |
2017 |
Food Chem. Toxicol. |
pmid:28870684
|
Zeng J et al. |
Isoliquiritigenin alleviates early brain injury after experimental intracerebral hemorrhage via suppressing ROS- and/or NF-κB-mediated NLRP3 inflammasome activation by promoting Nrf2 antioxidant pathway. |
2017 |
J Neuroinflammation |
pmid:28610608
|
Köksal Z et al. |
The inhibition effects of some natural products on lactoperoxidase purified from bovine milk. |
2017 |
J. Biochem. Mol. Toxicol. |
pmid:28594102
|
Kim DH et al. |
Isoliquiritigenin inhibits the proliferation of human renal carcinoma Caki cells through the ROS-mediated regulation of the Jak2/STAT3 pathway. |
2017 |
Oncol. Rep. |
pmid:28560439
|
Yang HH et al. |
Isoliquiritigenin Induces Cytotoxicity in PC-12 Cells In Vitro. |
2017 |
Appl. Biochem. Biotechnol. |
pmid:28488118
|
Chen XY et al. |
Reprogramming induced by isoliquiritigenin diminishes melanoma cachexia through mTORC2-AKT-GSK3β signaling. |
2017 |
Oncotarget |
pmid:28410220
|
Boyapelly K et al. |
Synthesis and Characterization of a Phosphate Prodrug of Isoliquiritigenin. |
2017 |
J. Nat. Prod. |
pmid:28252963
|
Chi JH et al. |
Isoliquiritigenin inhibits TNF-α-induced release of high-mobility group box 1 through activation of HDAC in human intestinal epithelial HT-29 cells. |
2017 |
Eur. J. Pharmacol. |
pmid:28012970
|
Wu CH et al. |
Isoliquiritigenin induces apoptosis and autophagy and inhibits endometrial cancer growth in mice. |
2016 |
Oncotarget |
pmid:27708238
|
Jin XY et al. |
Isoliquiritigenin suppresses tumor necrosis factor-α-induced inflammation via peroxisome proliferator-activated receptor-γ in intestinal epithelial cells. |
2016 |
Arch. Pharm. Res. |
pmid:27539609
|
Cao L- et al. |
Isoliquiritigenin protects against triptolide-induced hepatotoxicity in mice through Nrf2 activation. |
2016 |
Pharmazie |
pmid:29441915
|
Kong BJ et al. |
Properties and in vitro drug release of hyaluronic acid-hydroxyethyl cellulose hydrogels for transdermal delivery of isoliquiritigenin. |
2016 |
Carbohydr Polym |
pmid:27178954
|
Wang Y et al. |
Isoliquiritigenin Inhibits Proliferation and Induces Apoptosis via Alleviating Hypoxia and Reducing Glycolysis in Mouse Melanoma B16F10 Cells. |
2016 |
Recent Pat Anticancer Drug Discov |
pmid:26951491
|
Liu S et al. |
Anti-osteoclastogenic activity of isoliquiritigenin via inhibition of NF-κB-dependent autophagic pathway. |
2016 |
Biochem. Pharmacol. |
pmid:26947453
|
Choi YH et al. |
Isoliquiritigenin ameliorates dextran sulfate sodium-induced colitis through the inhibition of MAPK pathway. |
2016 |
Int. Immunopharmacol. |
pmid:26771170
|
Peng F et al. |
Cytotoxic Evaluation against Breast Cancer Cells of Isoliquiritigenin Analogues from Spatholobus suberectus and Their Synthetic Derivatives. |
2016 |
J. Nat. Prod. |
pmid:26690274
|
Park SM et al. |
Isoliquiritigenin in licorice functions as a hepatic protectant by induction of antioxidant genes through extracellular signal-regulated kinase-mediated NF-E2-related factor-2 signaling pathway. |
2016 |
Eur J Nutr |
pmid:26593436
|
Yamaura K et al. |
Discovery of allosteric modulators for GABAA receptors by ligand-directed chemistry. |
2016 |
Nat. Chem. Biol. |
pmid:27526031
|
Weis KE and Raetzman LT |
Isoliquiritigenin exhibits anti-proliferative properties in the pituitary independent of estrogen receptor function. |
2016 |
Toxicol. Appl. Pharmacol. |
pmid:27702603
|
Gaur R et al. |
Drug Resistance Reversal Potential of Isoliquiritigenin and Liquiritigenin Isolated from Glycyrrhiza glabra Against Methicillin-Resistant Staphylococcus aureus (MRSA). |
2016 |
Phytother Res |
pmid:27388327
|
Peng F et al. |
The application of HPLC-MS/MS to studies of pharmacokinetics and interconversion of isoliquiritigenin and neoisoliquiritigenin in rats. |
2016 |
Biomed. Chromatogr. |
pmid:26577957
|
Chen X et al. |
Differentiation-inducing and anti-proliferative activities of isoliquiritigenin and all-trans-retinoic acid on B16F0 melanoma cells: Mechanisms profiling by RNA-seq. |
2016 |
Gene |
pmid:27461947
|
Mahalingam S et al. |
Effects of isoliquiritigenin on ovarian antral follicle growth and steroidogenesis. |
2016 |
Reprod. Toxicol. |
pmid:27773742
|
Park SJ et al. |
Isoliquiritigenin impairs insulin signaling and adipocyte differentiation through the inhibition of protein-tyrosine phosphatase 1B oxidation in 3T3-L1 preadipocytes. |
2016 |
Food Chem. Toxicol. |
pmid:27117918
|