isoliquiritigenin

Isoliquiritigenin is a lipid of Polyketides (PK) class. Isoliquiritigenin is associated with abnormalities such as abnormal fragmented structure, Gastric ulcer, Gastric mucosa lesion, Peptic Ulcer and Wiskott-Aldrich Syndrome. The involved functions are known as Mass-to-Charge Ratio, Anabolism, Oxidation, inhibitors and Energy Absorption. Isoliquiritigenin often locates in Microsomes, Liver, Hepatic, Microsomes, Immune system and Vacuole. The associated genes with Isoliquiritigenin are P4HTM gene, BCL2 gene, AP1AR gene, oxytocin, 1-desamino-(O-Et-Tyr)(2)- and ODAM gene. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of isoliquiritigenin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with isoliquiritigenin?

isoliquiritigenin is suspected in Gastric mucosa lesion, Gastric ulcer, Peptic Ulcer, Nodule, Infertility and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with isoliquiritigenin

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Precancerous Conditions D011230 48 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Glioma D005910 112 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Leiomyoma D007889 8 associated lipids
Per page 10 20 | Total 13

PubChem Associated disorders and diseases

What pathways are associated with isoliquiritigenin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with isoliquiritigenin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with isoliquiritigenin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with isoliquiritigenin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with isoliquiritigenin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with isoliquiritigenin?

Knock-out

Knock-out are used in the study 'Two activators of in vitro fertilization in mice from licorice.' (Tung NH et al., 2015).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with isoliquiritigenin

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Authors Title Published Journal PubMed Link
Cao L- et al. Isoliquiritigenin protects against triptolide-induced hepatotoxicity in mice through Nrf2 activation. 2016 Pharmazie pmid:29441915
Kong BJ et al. Properties and in vitro drug release of hyaluronic acid-hydroxyethyl cellulose hydrogels for transdermal delivery of isoliquiritigenin. 2016 Carbohydr Polym pmid:27178954
Wang Y et al. Isoliquiritigenin Inhibits Proliferation and Induces Apoptosis via Alleviating Hypoxia and Reducing Glycolysis in Mouse Melanoma B16F10 Cells. 2016 Recent Pat Anticancer Drug Discov pmid:26951491
Weis KE and Raetzman LT Isoliquiritigenin exhibits anti-proliferative properties in the pituitary independent of estrogen receptor function. 2016 Toxicol. Appl. Pharmacol. pmid:27702603
Du F et al. Isoliquiritigenin Attenuates Atherogenesis in Apolipoprotein E-Deficient Mice. 2016 Int J Mol Sci pmid:27869741
Gaur R et al. Drug Resistance Reversal Potential of Isoliquiritigenin and Liquiritigenin Isolated from Glycyrrhiza glabra Against Methicillin-Resistant Staphylococcus aureus (MRSA). 2016 Phytother Res pmid:27388327
Wu J et al. Simultaneous Determination of Multiple Components in Guanjiekang in Rat Plasma via the UPLC-MS/MS Method and Its Application in Pharmacokinetic Study. 2016 Molecules pmid:27999285
Chen X et al. Differentiation-inducing and anti-proliferative activities of isoliquiritigenin and all-trans-retinoic acid on B16F0 melanoma cells: Mechanisms profiling by RNA-seq. 2016 Gene pmid:27461947
Mahalingam S et al. Effects of isoliquiritigenin on ovarian antral follicle growth and steroidogenesis. 2016 Reprod. Toxicol. pmid:27773742
Park SJ et al. Isoliquiritigenin impairs insulin signaling and adipocyte differentiation through the inhibition of protein-tyrosine phosphatase 1B oxidation in 3T3-L1 preadipocytes. 2016 Food Chem. Toxicol. pmid:27117918