4'-Methoxychalcone

4'-Methoxychalcone is a lipid of Polyketides (PK) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 41 references associated with 4'-Methoxychalcone in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 4'-Methoxychalcone

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4'-Methoxychalcone

MeSH term MeSH ID Detail
Lung Neoplasms D008175 171 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Total 2

NCBI Entrez Crosslinks

All references with 4'-Methoxychalcone

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Authors Title Published Journal PubMed Link
Hsieh CT et al. 2-Bromo-4'-methoxychalcone and 2-Iodo-4'-methoxychalcone Prevent Progression of Hyperglycemia and Obesity via 5'-Adenosine-Monophosphate-Activated Protein Kinase in Diet-Induced Obese Mice. 2018 Int J Mol Sci pmid:30223438
Han Y et al. Regulatory effects of 4-methoxychalcone on adipocyte differentiation through PPARγ activation and reverse effect on TNF-α in 3T3-L1 cells. 2017 Food Chem. Toxicol. pmid:28528971
Shakil NA et al. Microwave synthesis, characterization and bio-efficacy evaluation of novel chalcone based 6-carbethoxy-2-cyclohexen-1-one and 2H-indazol-3-ol derivatives. 2013 Eur J Med Chem pmid:23229055
Lim J et al. 4-methoxychalcone enhances cisplatin-induced oxidative stress and cytotoxicity by inhibiting the Nrf2/ARE-mediated defense mechanism in A549 lung cancer cells. 2013 Mol. Cells pmid:24046186
Kim YS et al. Methoxychalcone inhibitors of androgen receptor translocation and function. 2012 Bioorg. Med. Chem. Lett. pmid:22310230
Kumar V et al. Novel chalcone derivatives as potent Nrf2 activators in mice and human lung epithelial cells. 2011 J. Med. Chem. pmid:21539383
Burns AR et al. A predictive model for drug bioaccumulation and bioactivity in Caenorhabditis elegans. 2010 Nat. Chem. Biol. pmid:20512140
Montes-Avila J et al. Solution-phase parallel synthesis of substituted chalcones and their antiparasitary activity against Giardia lamblia. 2009 Bioorg. Med. Chem. pmid:19683930
Souza AM et al. Leishmania amazonensis growth inhibitors: biological and theoretical features of sulfonamide 4-methoxychalcone derivatives. 2009 Curr. Microbiol. pmid:19629593
Meng CQ et al. Discovery of novel heteroaryl-substituted chalcones as inhibitors of TNF-alpha-induced VCAM-1 expression. 2004 Bioorg. Med. Chem. Lett. pmid:15006393